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| 1 | Hepatitis B virus prevalence and transmission risk factors in inflammatory bowel disease patients at Clementino Fraga Filho university hospital显示文摘AIM: To evaluate the prevalence of hepatitis B virus (HBV) infection in inflammatory bowel disease (IBD) patients that followed up in our hospital and try to identify the possible risk factors involved in this infection transmission. METHODS: This was a cross-sectional study for which 176 patients were selected according to their arrival for the medical interview. All these patients had already IBD diagnosis. The patient was interviewed and a questionnaire was filled out. RESULTS: In the group of 176 patients whom we examined, we found that 17% (30) were anti-HBc positive. Out of 30 patients with positive anti-HBc, 2.3% (4) had positive HBsAg and negative HBV-DNA. In an attempt to identify the possible HBV infection transmission risk factors in IBD patients, it was observed that 117 patients had been submitted to some kind of surgical procedure, but only 24 patients had positive anti-HBc (P = 0.085). It was also observed that surgery to treat IBD complications was not a risk factor for HBV infection transmission, since we did not get a statically significant P value. However, IBDpatients that have been submitted to surgery to treat IBD complications received more blood transfusions then patients submitted to other surgical interventions (P = 0.015). CONCLUSION: There was a high incidence of positive anti-HBc (17%) and positive HBsAg (2.3%) in IBD patient when compared with the overall population (7.9%). | Yolanda Faia Manhes Tolentino Homero Soares Fogaa Cyrla Zaltman Lia Laura Lewis Ximenes Henrique Sérgio Moraes Coelho | 2008 | World Journal of Gastroenterology2008，14，20： | 10 |
| 2 | Zika virus intrauterine infection causes fetal brain abnormality and microcephaly:tip of the iceberg Ultrasound Obstet Gynecol显示文摘 | Oliveira Melo A S Malinger G Ximenes R | 2016 | 47(1):6-72016，47，1： | 1 |
| 3 | Initial description of the presumed congenital Zika syndrome显示文摘 | Miranda-Filho Ode B Martelli CM Ximenes RA | 2016 | Am J Public Health2016，106，4： | 1 |
| 4 | Polarographic determination of nitrate in vegetables显示文摘 | Ximenes M I N Rath S Reyes F G R | 2000 | Talanta2000，51，1： | 1 |
| 5 | Effect of endodontic irrigation with 1% sodium hypochlorite and 17% EDTA on primary teeth: a scanning electron microscope analysis 显示文摘 | Ximenes M Triches TC Beltrame AP | 2013 | Gen Dent2013，61，2： | 1 |
| 6 | Organoch lorinepes ticides and polychlorinated biphenyls in soil and water samples in the Northeastern part of Sao Paulo State,Brazil显示文摘 | Rissato S R Galhiane M S Ximenes V F | 2006 | Chemosphere2006，65，： | 1 |
| 7 | Clinical efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor prognostic factors显示文摘 | Westhovens R Robles M Ximenes A C | 2009 | Ann Rheum Dis2009，68，12： | 1 |
| 8 | Pertussis may be the cause of prolonged cough in adolescents and adults in the interepidemic period显示文摘 | Pimentel AM Baptista PN Ximenes RA | 2015 | Braz J Infect Dis2015，19，1： | 1 |
| 9 | Neutrophils as a spe- cific target for melatonin and kynuramines effects on cytokine re- lease显示文摘 | Silva SO Rodrigues MR Ximenes VF | 2004 | J Neuroimmuno12004，156，12： | 1 |
| 10 | The decomposition of woodproducts in landfills in Sydney, Australia显示文摘 | Ximenes F A Gardner W D Cowie A L | 2008 | Waste Management2008，28，11： | 1 |
| 11 | Randomised controlled trial of tetanus treatment with antitetanus immunoglobul in by the intrathecal or intramuscular route显示文摘 | Miranda-Filho DB Ximenes RA Barone AA | 2004 | BMJ2004，328，7440： | 1 |
| 12 | Lignin monomer composition affects Arabidopsis cell wall degradability after liquid hot wa- ter pretreatment显示文摘 | Li X Ximenes E Kim Y | 2010 | Biotechnol Biofuels2010，3，： | 1 |
| 13 | Psychometric assess- ment of the Brazilian version of the Breastfeeding Self - Efficacy Scale显示文摘 | Orid MO Ximenes LB Almeida PC | 2009 | Public Health Nursing2009，26，6： | 1 |
| 14 | An analytical study of first-and third-order chromatic aberrations for Hutter's electrostatic immersion lenses显示文摘 | Liu Z Ximen J J | 1999 | Optik1999，10，11： | 1 |
| 15 | Inhibition of cellulases by phenols显示文摘 | Ximenes E Kim Y Mosier N | 2010 | Enzyme and Microbial Technology2010，46，34： | 1 |
| 16 | Smoking increases the risk of relapse after successful tuberculosis treatment 显示文摘 | d'Arc Lyra Batista J de F6tima Pessoa Militao de Albuquerque M de Alencar Ximenes RA | 2008 | Int J Epide- miol2008，37，4： | 1 |
| 17 | Chemiluminescent determination of leukocyte alkaline phosphatase: an advantageous alternative to the cytochemical assay显示文摘 | Kanegae MP Ximenes VF Falcao RP | 2007 | J Clin Lab Anal2007，21，： | 1 |
| 18 | Fatigue reliability and inspection of TLP tendon system显示文摘 | Ximenes M C C | | 0，，02： | 1 |
| 19 | Organochlorine pesticides and polychlorinated biphenyls in soil and water samples in the northeastern part of Sao Paulo State,Brazil显示文摘 | Galhiane MS Ximenes VF | 2006 | Chemosphere2006，65，11： | 1 |
| 20 | Antiglycation and antioxidant activities of the crude extract and saponin fraction of Tribulus terrestris before and after microcapsule release显示文摘Objective:The present study investigated antiglycation and antioxidant activities of crude dry extract and saponin fraction of Tribulus terrestris.It also developed a method of microencapsulation and evaluated antiglycation and antioxidant activities of crude dry extract and saponin fraction before and after microcapsule release.Methods:Antiglycation activity was determined by relative electrophoretic mobility(REM),free amino groups and inhibition of advanced glycation end-product(AGE)formation.Antioxidant activity was determined by 2,2-diphenyl-1-picrylhydrazyl(DPPH),ferric ion-reducing antioxidant power(FRAP),nitric oxide(NO)and thiobarbituric acid reactive species(TBARS)tests.Microcapsules were prepared using maltodextrin as wall material and freeze-drying as encapsulation technique.Morphological characterization of microcapsules was evaluated by scanning electron microscopy,and encapsulation efficiency and microcapsule release were determined by total saponins released.Antiglycation and antioxidant assays were performed using crude dry extract and saponin fraction of T.terrestris before and after release.Results:Saponin fraction showed an increase of 32.8%total saponins.High-performance liquid chromatography-mass spectrometry analysis showed the presence of saponins in the obtained fraction.Antiglycation evaluation by REM demonstrated that samples before and after release presented antiglycation activity similar to bovine serum albumin treated with aminoguanidine.Additionally,samples inhibited AGE formation,highlighting treatment with saponin fraction after release(89.89%).Antioxidant tests demonstrated antioxidant activity of the samples.Crude dry extract before encapsulation presented the highest activities in DPPH(92.00%)and TBARS(32.49%)assays.Saponin fraction before encapsulation in FRAP test(499μmol Trolox equivalent per gram of dry sample)and NO test(15.13μmol nitrite formed per gram of extract)presented the highest activities.Conclusion:This study presented antiglycation activity of crude dry extract and saponin fraction of T.terrestris,besides it demonstrated promising antioxidant properties.It also showed that the encapsulation method was efficient and maintained biological activity of bioactive compounds after microcapsule release.These results provide information for further studies on antidiabetic and antiaging potential,and data for new herbal medicine and food supplement formulations containing microcapsules with crude extract and/or saponin fraction of T.terrestris. | Célia Cristina Malaguti Figueiredo Amanda da Costa Gomes Filipe Oliveira Granero Joao Luiz Bronzel Junior Luciana Pereira Silva Valdecir Farias Ximenes Regildo Márcio Goncalves da Silva | 2022 | Journal of Integrative Medicine2022，20，2： | 1 |
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