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| 1 | Effect of Exogenous Ghrelin on Cell Differentiation Antigen 40 Expression in Endothelial Cells显示文摘Ghrelin 是为生长荷尔蒙促泌素受体(GHSR ) 用作自然配体的大脑勇气肽。它也在心血管的系统富有地存在。以便在动脉粥样硬化的发展评估 ghrelin 的可能的角色,房间区别抗原 40 的表示(CD40 ) 上的 ghrelin 的效果被学习。人的脐的静脉 endothelial 房间(HUVEC ) line-ECV 304 与 ghrelin 的不同集中被预先对待, des 酰 ghrelin 或[d-Lys ]-GHRP-6 (一个 ghrelin 受体对手) ,然后与肿瘤坏死 factor-alpha (TNF-alpha ) 和干扰素鲸鱼群妈(TFN-gamma ) 导致了。CD40 的 mRNA 层次被反向的抄写聚合酶链反应分析,并且在房间的 CD40 蛋白质的表情被流动 cytometry (FCM ) 并且西方的弄污测量。结果证明外长的 ghrelin 能显著地禁止 TNF-alpha/IFN-gamma 在以一种集中依赖者方式的 HUVEC 房间的导致的 CD40 表示。当与 ghrelin 的 1000 ng/ml 对待时,在房间的 CD40 的 mRNA 水平被约77%减少,但是当与 ghrelin 的 1000 ng/ml 和 1000 ng/ml 对待时[ d-Lys ]-GHRP-6,在房间的 CD40 的 mRNA 水平被减少由仅仅42%,建议那[ d-Lys ] -GHRP-6 能在这些房间抵抗 ghrelin 的禁止的效果。然而, CD40 表示没被 des 酰 ghrelin 在 1000 ng/ml 禁止。在 FCM 并且进一步的西方的弄污检测的蛋白质表示分析的结果证实了这些结果。我们的结果在心血管的系统建议了那, ghrelin 不仅有反煽动性的效果,而且有重要免疫可以通过 GHSR-1a 受体被调停的规章的效果。 | Min ZHANG Fang YUAN Hui CHEN Xingbiao QIU Weiyi FANG | 2007 | Acta Biochimica et Biophysica Sinica2007，39，12： | 8 |
| 2 | Inhibition of proliferation and apoptosis of vascular smooth muscle cells by ghrelin显示文摘在动脉粥样硬化的发展评估 ghrelin 的可能的角色,它肿瘤上的效果脉管的光滑的肌肉房间(VSMC ) 的坏死因素(TNF )-α-induced 增长和 apoptosis 被调查。老鼠 VSMC 是有 ghrelin 的不同集中然后与 TNF-α 的 pretreated。VSMC 增长被 3-(4,5-dimethylthiazol-2-yl ) 测量 -2,5-diphenyl tetrazolium 溴化物试金和流动 cytometry 方法。Apoptosis 用 propidium 碘化物和 Annexin-V 标记方法被检测。外长的 ghrelin (10-1000 ng/ml ) 显著地以一种集中依赖者方式禁止了 VSMC 的 TNF-α-induced 增长。有 1000 ng/ml ghrelin 的处理在禁止 VSMC 增长率和增殖的房间的表示是很有效的原子抗原。然而,有 des 酰 ghrelin 的处理影响了既不增长也不 PCNA 表示。相反, VSMC 的 TNF-α-induced apoptosis 被 ghrelin 和 des 酰 ghrelin 在集中依赖者礼貌禁止,与为在 1000 ng/ml 的两混合物观察的最大的抑制。总起来说,我们的结果建议 ghrelin 禁止了老鼠 VSMC 的增长和 apoptosis。而且,以前的效果被生长荷尔蒙促泌素受体类型 la 受体可能调停,当后者效果可以通过另外的受体被调停时。 | Min Zhang Fang Yuan Hua Liu Hui Chen Xingbiao Qiu Weiyi Fang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，9： | 8 |
| 3 | A transformer-based Siamese network and an open optical dataset for semantic change detection of remote sensing images显示文摘Recent change detection(CD)methods focus on the extraction of deep change semantic features.However,existing methods overlook the fine-grained features and have the poor ability to capture long-range space–time information,which leads to the micro changes missing and the edges of change types smoothing.In this paper,a potential transformer-based semantic change detection(SCD)model,Pyramid-SCDFormer is proposed,which precisely recognizes the small changes and fine edges details of the changes.The SCD model selectively merges different semantic tokens in multi-head self-attention block to obtain multiscale features,which is crucial for extraction information of remote sensing images(RSIs)with multiple changes from different scales.Moreover,we create a well-annotated SCD dataset,Landsat-SCD with unprecedented time series and change types in complex scenarios.Comparing with three Convolutional Neural Network-based,one attention-based,and two transformer-based networks,experimental results demonstrate that the Pyramid-SCDFormer stably outperforms the existing state-of-the-art CD models and obtains an improvement in MIoU/F1 of 1.11/0.76%,0.57/0.50%,and 8.75/8.59%on the LEVIR-CD,WHU_CD,and Landsat-SCD dataset respectively.For change classes proportion less than 1%,the proposed model improves the MIoU by 7.17–19.53%on Landsat-SCD dataset.The recognition performance for small-scale and fine edges of change types has greatly improved. | Panli Yuan Qingzhan Zhao Xingbiao Zhao Xuewen Wang Xuefeng Long Yuchen Zheng | 2022 | International Journal of Digital Earth2022，15，1： | 2 |
| 4 | Application of Hirota' s bilinear formalism to the Toeplitz lattice-some special soliton- like solutions 显示文摘 | HU Xingbiao MA Wenxiu | 2002 | Phys Lett A2002，，293： | 1 |
| 5 | Application of Hirota's bilinear formalism to the Toeplitz lattice-some special soliton-like solutions显示文摘 | HU Xingbiao MA Wenxiu | 2002 | Phys Lett A2002，293，： | 1 |
| 6 | Pfaffianization of the differential-difference KP equation显示文摘 | ZHAO JUNXIAO LI CHUNXIA HU XINGBIAO | 2004 | J Phys Soc Japan2004，73，： | 1 |
| 7 | New type of KP equation with self-consistent sources and its bilinear B~klund transformation显示文摘 | Hu Xingbiao Wang Hongyan | 2007 | Inverse Problems2007，23，4： | 1 |
| 8 | A (2 + 1 ) -dimensional Sasa-Satsuma equation with self-consistent source显示文摘 | Wang Hongyan Hu Xingbiao Tam H W | 2007 | J Phys Soc Jpn2007，76，02： | 1 |
| 9 | A hydroxyl radical detection system using gas expansion and fast gating laser-induced fluorescence techniques显示文摘An OH radical measurement instrument based on Fluorescence Assay by Gas Expansion(FAGE)has been developed in our laboratory.Ambient air is introduced into a low-pressure fluorescence cell through a pinhole aperture and irradiated by a dye laser at a high repetition rate of 8.5 k Hz.The OH radical is both excited and detected at 308 nm using A-X(0,0)band.To satisfy the high efficiency needs of fluorescence collection and detection,a 4-lens optical system and a self-designed gated photomultiplier(PMT)is used,and gating is actualized by switching the voltage applied on the PMT dynodes.A micro channel photomultiplier(MCP)is also prepared for fluorescence detection.Then the weak signal is accumulated by a photon counter in a specific timing.The OH radical excitation spectrum range in the wavelength of 307.82–308.2 nm is detected and the excited line for OH detection is determined to be Q_1(2)line.The calibration of the FAGE system is researched by using simultaneous photolysis of H_2O and O_2.The minimum detection limit of the instrument using gated PMT is determined to be 9.4×10~5molecules/cm^3,and the sensitivity is 9.5×10^(-7)cps/(OH·cm^(-3)),with a signal-to-noise ratio of 2 and an integration time of 60 sec,while OH detection limit and the detection sensitivity using MCP is calculated to be 1.6×10~5molecules/cm^3and 2.3×10^(-6)cps/(OH·cm^(-3)).The laboratory OH radical measurement is carried out and results show that the proposed system can be used for atmospheric OH radical measurement. | Hao Chen Renzhi Hu Pinhua Xie Xingbiao Xing Liuyi Ling Zhiyan Li Fengyang Wang Yihui Wang Jianguo Liu Wenqing Liu | 2018 | Journal of Environmental Sciences2018，30，3： | 1 |
| 10 | Construction of dKP and BKP equations with self-consistent sources显示文摘 | Hu Xingbiao Wang Hongyan | | 0，，05： | 1 |
| 11 | A (2 + 1)-dimensional Sasa-Satsuma equation with self-consistent sources显示文摘 | Wang Hongyan Hu Xingbiao Tam H W | | 0，，02： | 1 |
| 12 | New type of KP equation with self-consistent sources and its bilinear B(a)cklund transformation显示文摘 | Hu Xingbiao Wang Hongyan | | 0，，04： | 1 |
| 13 | Nonlocal Lie-Backlund Symmetries and Olver Symmetries of the KdV Equation显示文摘Starting from a special nonlocal Lie Backlund symmetry of the KdV,mKdV,potential mKdV and singularity manifold equation system,three sets of higher order nonlocal Olver syiniuetries are reobtained.The soliton solutions of these models can also be obtained from the finite Lie-Backlund transformations. | LOU Senyue HU Xingbiao | 1993 | Chinese Physics Letters1993，10，10： | 1 |
| 14 | An approach to generate superextensions of integrable systems显示文摘 | Hu Xingbiao | 1997 | Journal of Physics A: Mathematical and Gen- eral1997，30，2： | 1 |
| 15 | The Hirota-Satsuma coupled KdV equation and a coupled ito system revisited显示文摘 | Hon wah TAM Ma Wenxiu Hu Xingbiao | 2000 | Journal of the Physical Society of Japan2000，69，1： | 1 |
| 16 | Application of Hirota's bilinear formalism to the Toeplitz lattice-some special soliton-like solutions显示文摘 | Xingbiao H U Wenxiu M A | 2002 | Phys Lett A2002，293，： | 1 |
| 17 | Design and Implementation of the Platform for Multimedia Resource Sharing based on Cloud Technology显示文摘 | Ling Yang Xingbiao Zi | 2014 | International Journal of Technology Management2014，，7： | 0 |
| 18 | Coupled modified Kd V equations, skew orthogonal polynomials, convergence acceleration algorithms and Laurent property显示文摘In this paper, we show that the coupled modified Kd V equations possess rich mathematical structures and some remarkable properties. The connections between the system and skew orthogonal polynomials,convergence acceleration algorithms and Laurent property are discussed in detail. | Xiangke Chang Yi He Xingbiao Hu Shihao Li Hon-wah Tam Yingnan Zhang | 2018 | Science China Mathematics2018，61，6： | 0 |
| 19 | THE EFFECT OF ACUPUNCTURE ON PREVENTION AND TREATMENT OF ISCHEMIC ARRHYTHMIA AND THE RELATION BETWEEN EFFECT OF ACUPUNCTURE AND CHOLINERGIC MUSCARINE-LIKE RECEPTORS显示文摘For investigating the effect of acupuncture on ischemic arrhythmia and its mech-anism, adult albino rats with ligated anterior descending branch of coronary artery as experimentalmodel were treated with or without acupuncture, and others with imitative operation but without bothcoronary artery ligation and acupuncture treatment were used as control. It was found in acupuncturegroup that the fibrillation-liability of ischemic myocardium was efficiently decreased, the affinity ofAch-M receptors on membranes of ischemic myocardium was markedly increased, and the tolerance ofischemic myocardium to atropine was elevated in the experiment of atropine inducing fibrillation.These results indicate that acupuncture may play a therapeutic role on ischemic arrhythmia throughactivating the activity of muscarine-like receptors of cholinergic nervous system. | Guan Xinmin Zhang Jian Shi Bo** Ouyang Xingbiao, Research Department of Acupuncture Anesthesia Mechanism & Department of Neurobiology, Tongji Medical University, Wuhan 430030, China Department of Physiology, Jinzhou School of Health, Jinzhou, Liaoning Province, China | 1993 | World Journal of Acupuncture-Moxibustion1993，3，1： | 0 |
| 20 | Recent Development in Symmetries and Integrability of Difference Equations显示文摘 | Xingbiao HU Qingping LIU Senyue LOU Changzheng QU Youjin ZHANG | 2013 | Frontiers of Mathematics in China2013，8，5： | 0 |
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