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9篇 您的检索式:作者名="XlAO Yu"
    题名 作者 年代 出处 被引量
1Preparation of folate-conjugated starch nanoparticles and its application to tumor-targeted drug delivery vector显示文摘Anion starch nanoparticles (StNP) were prepared in water-in-oil microemulsion. Folate modi-fied with PEG was conjugated to the surface of StNP to obtain the folate-conjugated starch nanoparticles (FA-PEG/StNP). The average diameter of FA-PEG/ StNP determined by AFM and Zeta-Sizer apparatus was about 130 nm. Doxorubicin (DOX)-loaded FA- PEG/StNP was obtained via infiltrating combination. The result of UV spectrophotometer showed that the saturation concentration of DOX-loaded FA-PEG/ StNP was 28 μg/mg, which was effective for the con-trolled release of anticancer drug DOX. The cell ex-periments showed that the Lc50 of DOX-loaded FA-PEG/StNP and DOX-loaded StNP was higher than that of DOX, which indicates that FA-PEG/StNP and StNP can decrease the toxicity of DOX; while the lethal rate of DOX-loaded FA-PEG/StNP was 3 times that of DOX-loaded StNP with the same quantity of DOX, which indicates that FA in FA-PEG/StNP is ef-fective for improving the targeting function of nanoparticles, thus enhancing the inhibition effect of anticancer drug to cancer cell. This work demon-strates that the FA-PEG/StNP system is a potentially useful system for the targeted delivery of anticancer drug DOX.XlAO Suyao TONG Chunyi LIU Xuanming YU Danmi LIU Qiaoling XUE Changgang TANG Dongyin ZHAO Lijian 2006Chinese Science Bulletin2006,51,14:12
2No association between LRP5 gene polymorphisms and bone and obesity phenotypes in Chinese maleoffspring nuclear families显示文摘Jin-bo YU Yao-hua KE Jin-wei HE Hao ZHANG Wei-wei HU Yun-qiu HU Miao LI Yu-juan LIU Jie-mei GU Wen-zhen FU Gao GAO Hua YUE Wen-jin XlAO Zhen-lin ZHANG 2010Acta Pharmacologica Sinica2010,31,11:3
3Di- rect-detection optical orthogonal frequency division multi- plexing system with new training sequence 显示文摘ZOU Wei-gang YU Jian-jun XlAO Jiang-nan 2012Fre- quenz2012,66,1:1
4Direct electrochemistry of myoglohin based on ionic liquid-clay composite films显示文摘Dai Z Xlao Y Yu X Z 2009Biosensors and Bioelectronics2009,24,:1
5Flipp- ed-exponential Nyquis pulse technique to optimize the PAPR in optical direct detection OFDM system显示文摘XlAO Jiang-nan YU Jian-jun CAO Zi-zheng 2013Op- tics Communications2013,286,:1
6Real-time target recognition system simulation based on laser near-field detection 显示文摘YU Xiao-liang MA Hui-min XlAO Jian 2009Optoelectron Lett2009,5,4:1
7Heterodyne de- tection and transmission of 60-Gbaud PDM-QPSK signal with SE of 4b/s/Hz显示文摘LI Xin-ying XlAO Jiang-nan YU Jian-jun 2014Optics Express2014,22,8:1
8Synthesis of polyoxometalate-polymer hybrid polymers and their hybrid vesicular assembly显示文摘HAN Yaokun XlAO Yu ZHANG Zijian 2009Macromolecules2009,42,17:1
9A 1 Gb/s CMOS optical receiver with regulated cascode scheme显示文摘XlAO Xin-dong MAO Lu-hong YU Chang-liang Journal of Optoelectronics : Laser0,21,4:1
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