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4篇 您的检索式:作者名="Xu Yuansen"
    题名 作者 年代 出处 被引量
13D bioprinting of integral ADSCs-NO hydrogel scaffolds to promote severe burn wound healing显示文摘Severe burns are challenging to heal and result in significant death throughout the world.Adiposederived mesenchymal stem cells(ADSCs)have emerged as a promising treatment for fullthickness burn healing but are impeded by their low viability and efficiency after grafting in vivo.Nitric oxide(NO)is beneficial in promoting stem cell bioactivity,but whether it can function effectively in vivo is still largely unknown.In this study,we bioprinted an efficient biological scaffold loaded with ADSCs and NO(3D-ADSCs/NO)to evaluate its biological efficacy in promoting severe burn wound healing.The integral 3D-ADSCs/NO hydrogel scaffolds were constructed via 3D bioprinting.Our results shown that 3D-ADSCs/NO can enhance the migration and angiogenesis of Human Umbilical Vein Endothelial Cells(HUVECs).Burn wound healing experiments in mice revealed that 3D-ADSCs/NO accelerated the wound healing by promoting faster epithelialization and collagen deposition.Notably,immunohistochemistry of CD31 suggested an increase in neovascularization,supported by the upregulation of vascular endothelial growth factor(VEGF)mRNA in ADSCs in the 3D biosystem.These findings indicated that 3D-ADSC/NO hydrogel scaffold can promote severe burn wound healing through increased neovascularization via the VEGF signalling pathway.This scaffold may be considered a promising strategy for healing severe burns.Yu Wu Tangzhao Liang Ying Hu Shihai Jiang Yuansen Luo Chang Liu Guo Wang Jing Zhang Tao Xu Lei Zhu 2021Regenerative Biomaterials2021,8,3:2
2Design aspects of CMOS compatible on chip antenna for applications of contact - less smart card 显示文摘Ni Hao Xu Yuansen 2003Chinese Journal of Semiconductors2003,24,5:1
3On the stress characteristics of graphite anode in commercial pouch lithium-ion battery显示文摘Dongren Liu Ying Wang Yuansen Xie Liping He Jie Chen Kai Wu Rui Xu Yan Gao 2013Journal of Power Sources2013,,:1
4A Novel Magnetic Bead-based Biosensor Using Flip Chip Bonding Techniques显示文摘Based on flip-chip packaging,a novel approach towards integrated magnetic bio-separator was designed.The magnetic field and the force on the bead were simulated and analyzed,leading to the optimization of the fabrication parameters of the micro-magnetic unit.The planar coil as an electromagnet was fabricated through electroplating on a single seed layer. The PDMS microfluidic channel was bonded on the inverse side after Si etching.The results presented in this paper provide a novel design and fabrication to approach a microfluidic bio-separation system with magnetic beads.Bin Wang Xiang Chen Qinghui Jin Jianlong Zhao Yuansen Xu 2006稀有金属材料与工程2006,35,A03:0
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