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| 1 | Proteomics in China:Ready for prime time显示文摘Proteomics is a newborn science focusing on the comprehensive systematic analysis of all proteins in molecule machineries,organelles,cells,tissues,organs or intact organisms.It has been becoming one of the focuses in life sciences and cutting-edge techniques in biotechnologies in the 21st century.During the last decade,proteomics in China has developed much faster than other developing fields in the life sciences.This review article briefly retrospects the origin and development of proteomics in China,and provides an overview of representative scientific progress and perspectives. | GAO Xue1,ZHANG XueLi1,ZHENG JunJie1 & HE FuChu1,2 1 State Key Laboratory of Proteomics,Beijing Proteome Research Center,Beijing Institute of Radiation Medicine,Beijing 102206,China 2 Institutes of Biomedical Sciences,Fudan University,Shanghai 200032,China | 2010 | Science China(Life Sciences)2010，53，1： | 10 |
| 2 | New progress of microbial prospecting of oil and gas in China:Taking the Satellite Oilfield in Daqing as an example显示文摘The Microbial Prospecting of Oil and Gas(MPOG) is applied to the matured development area in the Satellite Oilfield in Daqing for the first time. And with the MPOG,the hydrocarbon accumulation regulation controlled by faults is interpreted,and the matured development area is extended out to western part. At the same time,four microbial anomalies are discovered. The MPOG results were verified by the hydrocarbon-bearing conditions of the 10 drilled wells within the following half a year,and the consistent rate is up to 80%,which add about 300×104 t of the explored petroleum-in-place. Through study and successful application of MPOG to the Satellite Oilfield,the basis of the application from the exploration to development field is substantially established,and standard system of microbial anomaly is more precisely built for the Satellite Oilfield,which provided an effective explanatory item for the studied and adjacent region,even for the whole Songliao Basin,and also a new technique for complicated reservoirs,especially for the later stage development of litho-reservoirs in China. Therefore,it must have profound influence upon the oil and gas exploration,especially upon the remaining oil,extension and reserves addition of the developed area in China. | YUAN ZhiHua1,ZHANG YuQing1,ZHAO Qing1,JIANG HuFu2,LIU YunYan2,LUO ZhongHua2,LI Xue1,WANG ShiTou1,LI Bo1,PAN GuoHui2,GAO XingYou2 & ZHANG GuoLiang2 1 Geochemistry Department of Yangtze University,Key Laboratory of Oil & Gas Resource and Exploration Technique of Ministry of Education of China,Jingzhou 434023,China 2 The 8th Oil Recovery Plant of Daqing Oilfield Co. Ltd.,PetroChina,Daqing 163515,China | 2009 | Science China Earth Sciences2009，52，S1： | 5 |
| 3 | Human Causes of Aeolian Desertification in Northern China显示文摘Aeolian desertification has rapidly developed in the past 50 years in Northern China,covered an area of 0.386 million km2 by 2000,affected nearly 170 million population,and caused the direct and indirect economic loss of about $6.75(U.S.dollar) billion per year.Here we present several lines of evidence to demonstrate that human activities guided by policy shifts have been a major force to drive aeolian desertification via changes in land-use patterns and intensity.It is suggested that the desertification can be curbed or even reversed by adopting prevention and control measures with ecologically sound land-use practices in China. | Tao Wang1*,Xian Xue1,Yiqi Luo2,3,Xuhui Zhou2,Bao Yang1,Wanqun Ta1,Wei Wu4,Lihua Zhou1,Qingwei Sun1,XunmingWang1,Halin Zhao1,Xueyong Zhao1 1.Key Laboratory of Desert and Desertification,Cold and Arid Regions Environmental and Engineering Research Insti-tute,Chinese Academy of Sciences,Lanzhou Gansu 730000,China 2.Department of Botany and Microbiology,University of Oklahoma,Norman,Oklahoma 73019-0245,USA 3.School of Life Sciences,Fudan University,Shanghai 200433,China 4.Institute of Tibetan Plateau Research,Chinese Academy of Sciences,Beijing 100085,China | 2008 | Research in Cold and Arid Regions2008，，1： | 3 |
| 4 | miRNA and nasopharyngeal carcinoma显示文摘MicroRNAs(miRNAs) constitute a family of small non-coding RNA molecules 22-25 nucleotides in length.miRNAs control the expression of target genes at the post-transcriptional level by inhibiting translation or by degrading target mRNA through binding to complementary sequences in the 3'-untranslated regions.Recent studies have demonstrated that miRNAs are intimately involved in processes leading to nasopharyngeal carcinoma,such as the Epstein-Barr virus-encoded latent membrane protein 1 activated signal transduction pathways,gene-regulatory networks,mitosis,tumor angiogenesis,invasion and migration.Exploring the relationship between miRNAs and the development of nasopharyngeal carcinoma,will further the understanding of this cancer and provide new avenues for diagnosis and treatment. | ZHAO LuQing1,2,3,CHEN Xue1,2,3 & CAO Ya1,2,3 1 Key Laboratory of Carcinogenesis and Invasion,Ministry of Education,Changsha 410078,China 2 Key Laboratory of Carcinogenesis,Ministry of Health,Changsha 410078,China 3 Cancer Research Institute,Xiangya School of Medicine,Central South University,Changsha 410078,China | 2011 | Chinese Science Bulletin2011，56，8： | 2 |
| 5 | On 3D simulation of moving objects in a digital earth system显示文摘'How do the rescue helicopters find out an optimized path to arrive at the site of a disaster as soon as possible?' or 'How are the flight procedures over mountains and plateaus simulated?' and so on.In this paper a script language on spatial moving objects is presented by abstracting 3D spatial moving objects' behavior when implementing moving objects simulation in 3D digital Earth scene,which is based on a platform of digital China named 'ChinaStar'.The definition of this script language,its morphology and syntax,its compiling and mediate language generating,and the behavior and state control of spatial moving objects are discussed emphatically.In addition,the language's applications and implementation are also discussed. | WENG JingNong1,WU Lun2,HUANG Jian1,WANG Yang1,YANG Xue1 & HU Bin1 1 College of Software,Beihang University,Beijing 100191,China 2 Institute of Geographical Information System and Remote Sensing,Peking University,Beijing 100871,China | 2008 | Science China(Technological Sciences)2008，51，S2： | 2 |
| 6 | Effect of Cryogenic Treatments on Mechanical Properties of 2A11 Aluminum Alloy显示文摘 | Junjie Wang Xiaodai Xue1 Zhenqiang Yang | | 0，，10： | 1 |
| 7 | The Antimicrobial Activity of Wool Fabrics Treated with Crosslinking Agents and Polyhexamethylene Biguanide显示文摘In this study,we used citric acid(CA)as a crosslinking agent,mixed with polyhexamethylene biguanide,to perform a pad-dry-cure treatment on wool fabrics to study its antimicrobial effects and physical properties. | ZHAO Xue1,HE JIN-xin1,ZHAN Yi-zhen2(1.College of Chemistry & Chemical Engineering Donghua University,Shanghai 201620,China)(2.Saintyear Holding Group Company,Hangzhou 311221,China) | 2009 | China Textile2009，，5： | 1 |
| 8 | A simple method of synthesizing multi-wall carbon nanotubes/SnO core/shell nanostructure显示文摘Multi-wall carbon nanotubes(MWNTs)/SnO core/shell nanosturcture was synthesized by a simple solution-based method,in which SnCl2 was solved in distilled water containing dispersed MWNTs,then stired,filtered and washed in ambient atmosphere,finally dryed in air at 90 ℃ for 6 h.The MWNTs/SnO core/shell nanostructure was characterized by X-ray diffraction(XRD),transmission electron microscopy(TEM).It is found that surface defects of MWNTs are necessary for the deposition of SnO.The mechanism of the SnO nanocoating formation through the hydrolysis of SnCl2 in water(4SnCl2+2H2OSn4(OH)2Cl6+2HCl) was presented. | SUN Xue1),CHU Yi2),WANG Dawei3),DU Jinhong3),ZHANG Baoyou2),and WANG Fuping1)1) School of Science,Harbin Institute of Technology,Harbin 150001,China 2) School of Materials Science and Engineering,Harbin Institute of Technology,Harbin 150001,China 3) Shenyang National Laboratory for Materials Science,Institute of Metal Research,Chinese Academy of Sciences,Shenyang 110016,China | 2007 | Rare Metals2007，26，S1： | 0 |
| 9 | Anti-diarrheal and spasmolytic activities study of 3,4-Dihydro-2-(4-Morpholinylmethy)-1(2H)-Naphthalenone(CY)显示文摘Objective To investigate the spasmolytic and anti-diarrheal activities of 3,4-dihydro-2-(4-morpholinylmethy)-1(2H)-naphthalenone(CY),which was first synthesized by Welch,Willard M et al.in 1977.Methods The spasmolytic effects of CY were tested on isolated rabbit small intestine at the concentration of 0.01 to 3 mM;the diarrheal-index was evaluated on diarrhea mice to study the anti-diarrheal activities of CY.Results CY(0.1-1 mM)inhibited spontaneous motility of rabbit small intestine and at the concentration of 0.01 to 3 mM CY inhibited the contractile response of rabbit small intestine and colon induced by acetylcholine(10-2 mg·mL-1),high K+(60 mM)and BaCl2(1 mg·mL-1).When tested against calcium channel blocked in rabbit small intestine and colon,CY caused a rightward shift in the Ca2+ dose-response curves,similar to that produced by verapamil,a well-known calcium antagonist.CY could inhibit the diarrhea induced by castor oil,MgSO4 and liquid paraffin and LD50 of CY is 277.2 mg·kg-1.Conclusions CY may produce its spasmolytic and anti-diarrheal effects as a calcium antagonist. | WEI Wei1,FU Shou-ting1,LI Xue1,WEN Min1,HU Chun2(1.Department of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China 2.Department of Organic Chemistry,Shenyang Pharmaceutical University,Shenyang 110016,China) | 2008 | 沈阳药科大学学报2008，25，S1： | 0 |
| 10 | Association between the-1562 C/T polymorphism in the MMP-9 promoter and phenotype of esophageal squamous cell carcinoma in northern Chinese population显示文摘Objective To conduct a case-control study on the association of the nucleotide polymorphisms in the promoter region of the matrix metalloproteinase-9(MMP-9)gene with phenotype of esophageal cancer.Methods All subjects were unrelated residents in northern regions of China.Polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP)analysis was used to determine the MMP-9 genotypes.Results The overall distribution of genotypes in the patients was not different from that in the controls(OR=0.77,95% CI=0.45-1.34;P=0.36).There were no significant differences between the patients and the control subjects in terms of the distributions of sex and age,smoking status,alcohol dependence,pickled diet status,or history of environmental exposure.The patients were further examined with stratifications by age,sex,grade,depth of tumor invasion,lymphatic invasion,venous invasion and TNM staging.The results showed no pronounced association among the stratifications.Conclusion There is no significant association between the MMP-9 single nucleotide polymorphism genotypes and phenotype of esophageal cancer. | Peng Xia1,Dong-Min Chang1,Cheng-Xue Dang1,Lei Meng1,Hua Xue1,Yang Liu2 1.Department of Surgical Oncology,the First Affiliated Hospital,Medical School of Xi’an Jiaotong University,Xi’an 710061 2.Institute of Proteomics and Systems Biology,Zhongshan Hospital of Fudan University,Shanghai 200032,China. | 2010 | Journal of Pharmaceutical Analysis2010，22，1： | 0 |
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