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| 1 | Public health implications of Yersinia enterocolitica investigation:an ecological modeling and molecular epidemiology study显示文摘Background Yersinia enterocolitica has been sporadically recovered from animals,foods,and human clinical samples in various regions of Ningxia,China.However,the ecological and molecular characteristics of Y.enterocolitica,as well as public health concerns about infection in the Ningxia Hui Autonomous Region,remain unclear.This study aims to analyze the ecological and molecular epidemiological characteristics of Y.enterocolitis in order to inform the public health intervention strategies for the contains of related diseases.Methods A total of 270 samples were collected for isolation[animals(n=208),food(n=49),and patients(n=13)],then suspect colonies were isolated and identified by the API20E biochemical identification system,serological tests,biotyping tests,and 16S rRNA-PCR.Then,we used an ecological epidemiological approach combined with machine learning algorithms(general linear model,random forest model,and eXtreme Gradient Boosting)to explore the associations between ecological factors and the pathogenicity of Y.enterocolitis.Furthermore,average nucleotide identity(ANI)estimation,single nucleotide polymorphism(SNP),and core gene multilocus sequence typing(cgMLST)were applied to characterize the molecular profile of isolates based on whole genome sequencing.The statistical test used single-factor analysis,Chi-square tests,t-tests/ANOVA-tests,Wilcoxon rank-sum tests,and Kruskal–Wallis tests.Results A total of 270 isolates of Yersinia were identified from poultry and livestock(n=191),food(n=49),diarrhoea patients(n=13),rats(n=15),and hamsters(n=2).The detection rates of samples from different hosts were statistically different(χ^(2)=22.636,P<0.001).According to the relatedness clustering results,270 isolates were divided into 12 species,and Y.enterocolitica(n=187)is a predominated species.Pathogenic isolates made up 52.4%(98/187),while non-pathogenic isolates made up 47.6%(89/187).Temperature and precipitation were strongly associated with the pathogenicity of the isolates(P<0.001).The random forest(RF)prediction model showed the best performance.The prediction result shows a high risk of pathogenicity Y.enterocolitica was located in the northern,northwestern,and southern of the Ningxia Hui Autonomous Region.The Y.enterocolitica isolates were classified into 54 sequence types(STs)and 125 cgMLST types(CTs),with 4/O:3 being the dominant bioserotype in Ningxia.The dominant STs and dominant CTs of pathogenic isolates in Ningxia were ST429 and HC100_2571,respectively.Conclusions The data indicated geographical variations in the distribution of STs and CTs of Y.enterocolitica isolates in Ningxia.Our work offered the first evidence that the pathogenicity of isolates was directly related to fluctuations in temperature and precipitation of the environment.CgMLST typing strategies showed that the isolates were transmitted to the population via pigs and food.Therefore,strengthening health surveillance on pig farms in high-risk areas and focusing on testing food of pig origin are optional strategies to prevent disease outbreaks. | Yuan Yue Jinxin Zheng Mei Sheng Xiang Liu Qiong Hao Shunxian Zhang Shuai Xu Zhiguo Liu Xuexin Hou Huaiqi Jing Yang Liu Xuezhang Zhou Zhenjun Li | 2023 | Infectious Diseases of Poverty2023，12，2： | 1 |
| 2 | Analytical model of parallel thermoelectric generator显示文摘 | Liang Gaowei Zhou Jiemin Huang Xuezhang | 2011 | Applied En- ergy2011，，88： | 1 |
| 3 | Robust architecture of 2D nano Mg-based borohydride on graphene with superior reversible hydrogen storage performance显示文摘Efficient technical strategies to synthesize hydrides with high capacity and favorable reversibility are significant for the development of novel energy materials.Herein,nano Mg-based borohydride,Mg(BH_(4))_(2),with robust architecture was designed and prepared by confining on graphene through a solution selfconfinement method.The Mg(BH_(4))_(2) confined on graphene displays a wrinkled 2D nano layer morphology within 8.8 nm thickness.Such 2D nano Mg(BH_(4))_(2) can start dehydrogenation at 67.9℃ with a high capacity of 12.0 wt.%,which is 190.5℃ lower than pristine Mg(BH_(4))_(2).The isothermal dehydrogenation tests and kinetics fitting results indicate the 2D nano Mg(BH_(4))_(2) possesses much-enhanced dehydrogenation kinetics of 31.3 kJ/mol activation energy,which is only half of pristine Mg(BH_(4))_(2).The thermodynamics of the 2D nano Mg(BH_(4))_(2) is also verified by PCT tests,of which Gibbs free energy value for the confined 2D nano Mg(BH_(4))_(2) is estimated to be-18.01 kJ/mol H_(2),lower than-16.36 kJ/mol H_(2) of pristine Mg(BH_(4))_(2).Importantly,the reversibility of the confined 2D nano Mg(BH_(4))_(2) is significantly enhanced to over 90%capacity retention with relatively kinetics stability during 10 cycles.The mechanism analyses manifest that Mg(BH_(4))_(2) exhibits stable 2D nano morphology during 10 cyclic tests,resulting in the greatly reduced H diffusion path and the improved de/rehydrogenation kinetics of the 2D nano Mg(BH_(4))_(2).Based on theoretical calculations of Mg(BH_(4))_(2) and the intermediate MgB12H12 confined on graphene,the charge transfer status of both samples is modified to facilitate de/rehydrogenation,thus leading to the significant thermodynamic improvements of the reversible hydrogen storage performances for 2D nano Mg(BH_(4))_(2).Such investigation of the Mg-based borohydride will illuminate prospective technical research of energy storage materials. | Xuancheng Wang Yuxiao Jia Xuezhang Xiao Panpan Zhou Jiapeng Bi Jiacheng Qi Ling Lv Fen Xu Lixian Sun Lixin Chen | 2023 | Journal of Materials Science & Technology2023，，15： | 0 |
| 4 | A review of classical hydrogen isotopes storage materials显示文摘Hydrogen storage alloys(HSAs)are attracting widespread interest in the nuclear industry because of the generation of stable metal hydrides after tritium absorption,thus effectively preventing the leakage of radioactive tritium.Commonly used HSAs in the hydrogen isotopes field are Zr2M(M=Co,Ni,Fe)alloys,metallic Pd,depleted U,and ZrCo alloy.Specifically,Zr2M(M=Co,Ni,Fe)alloys are considered promising tritium-getter materials,and metallic Pd is utilized to separate and purify hydrogen isotopes.Furthermore,depleted U and ZrCo alloy are well suited for storing and delivering hydrogen isotopes.Notably,all the aforementioned HSAs need to modulate their hydrogen storage properties for complex operating conditions.In this review,we present a comprehensive overview of the reported modification methods applied to the above alloys.Alloying is an effective amelioration method that mainly modulates the properties of HSAs by altering their local geometrical/electronic structures.Besides,microstructural modifications such as nano-sizing and nanopores have been used to increase the specific surface area and active sites of metallic Pd and ZrCo alloys for enhancing de-/hydrogenation kinetics.The combination of metallic Pd with support materials can significantly reduce the cost and enhance the pulverization resistance.Moreover,the poisoning resistance of ZrCo alloy is improved by constructing active surfaces with selective permeability.Overall,the review is constructive for better understanding the properties and mechanisms of hydrogen isotope storage alloys and provides effective guidance for future modification research. | Yang Liu Zhiyi Yang Panpan Zhou Xuezhang Xiao Jiacheng Qi Jiapeng Bi Xu Huang Huaqin Kou Lixin Chen | 2024 | Materials Reports(Energy)2024，4，1： | 0 |
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