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| 1 | Shape-controlled synthesis of submicro-sized cuprous oxide octahedral显示文摘 | Xie Yi Xun Fen | 2003 | Inorganic Chemistry Communications2003，，6： | 1 |
| 2 | Effect of JIN's 3-needle technique and motor function training on upper extremities motor recovery of cerebral apoplexy induced hemiplegia 显示文摘 | ZHUANG Li xing XU Shi fen ZHUANG Xun | 2009 | World Journal of Acupuncture-M oxibustion (WJAM)2009，19，4： | 1 |
| 3 | 肝肠循环因子FGF15/19调节胆汁酸代谢从而控制肝脏尺寸大小与肝癌发生显示文摘文章简介肝脏是人体的一个重要代谢器官,它的大小相对于整个个体大小始终维持在一个合适的比例。肝脏如何感知生长起始和停止是肝脏发育、再生以及癌症生物学中一个有待解决的基本科学问题。近年来研究发现,Hippo信号通路在从果蝇到哺乳动物个体的器官发育及大小调控中都起着至关重要的作用。然而具体何种外部因子在调控Hippo信号通路来维持肝脏大小稳态及抑制癌症发生,一直是领域内未解决的问题。 | 姬素渊 刘清许 张世浩 陈青花 王聪 Weiji Zhang Chen Xiao Yuxi Li Cheng Nian Jiaxin Li Junhong Li Jing Geng Lixin Hong Changchuan Xie Ying He Xing Chen Xun Li Zhen-Yu Yin Han You Kwang-Huei Lin Qiao Wu Chundong Yu Randy L.Johnson Li Wang Lanfen Chen Fen Wang 周大旺 | 2020 | 科学新闻2020，，2： | 1 |
| 4 | Large area^(3)He tube array detector with modular design for multi‑physics instrument at CSNS显示文摘The multi-physics instrument(MPI)is the first user cooperative instrument at the China Spallation Neutron Source(CSNS).It was designed to explore the structures of complex materials at multiple scales based on the neutron total scattering technique.This imposes the requirements for the detector,including a high detection efficiency to reduce the measurement time and a large solid angle coverage to cover a wide range of momentum transfers.To satisfy these demands,a large-area array of 3He-filled linear position-sensitive detectors(LPSDs)was constructed,each with a diameter of 1 inch and pressure of 20 atm.It uses an orbicular layout of the detector and an eight-pack module design for the arrangement of 3He LPSDs,covering a range of scattering angles from 3°to 170°with a total detector area of approximately 7 m2.The detector works in air,which is separated from the vacuum environment to facilitate installation and maintenance.The characteristics of the MPI detector were investigated through Monte Carlo(MC)simulations using Geant4 and experimental measurements.The results suggest that the detectors are highly efficient in the wavelength range of the MPI,and an efficiency over 25%is achievable for above 0.1 A neutrons.A minimal position resolution of 6.4 mm full width at half maximum(FWHM)along the tube length was achieved at a working voltage of 2200 V,and a deviation below 2 mm between the real and measured positions was attained in the beam experiment.The detector module exhibited good consistency and an excellent counting rate capacity of up to 80 kHz,which satisfied the requirements of experiments with a high event rate.Observations of its operation over the past year have shown that the detector works steadily in sample experiments,which allows the MPI to serve the user program successfully. | Lin Zhu Jian‑Rong Zhou Yuan‑Guang Xia Liang Xiao Hong Luo Xiao‑Juan Zhou Wen‑Qin Yang Bei‑Ju Guan Xing‑Fen Jiang Yan‑Feng Wang Hong Xu Hai‑Yun Teng Li‑Xin Zeng Jia‑Jie Li Lei Hu Ke Zhou Yong‑Xiang Qiu Pei‑Xun Shen Jun Xu Li‑Jiang Liao Xiao‑Zhuang Wang Gui‑An Yang Huai‑Chan Chen Ju‑Ping Xu Zhi‑Duo Li Song‑Lin Wang Jian Zhuang Yu‑Bin Zhao Jun‑Rong Zhang Wen Yin Zhi‑Jia Sun Yuan‑Bo Chen | 2023 | Nuclear Science and Techniques2023，34，1： | 0 |
| 5 | Notoginsenoside Ft1 inhibits colorectal cancer growth by increasing CD8+T cell proportion in tumor-bearing mice through the USP9X signaling pathway显示文摘The management of colorectal cancer(CRC)poses a significant challenge,necessitating the development of innovative and effective therapeutics.Our research has shown that notoginsenoside Ft1(Ng-Ft1),a small molecule,markedly inhibits subcutaneous tumor formation in CRC and enhances the proportion of CD8+T cells in tumor-bearing mice,thus restraining tumor growth.Investigation into the mechanism revealed that Ng-Ft1 selectively targets the deubiquitination enzyme USP9X,undermining its role in shieldingβ-catenin.This leads to a reduction in the expression of downstream effectors in the Wnt signaling pathway.These findings indicate that Ng-Ft1 could be a promising small-molecule treatment for CRC,working by blocking tumor progression via the Wnt signaling pathway and augmenting CD8^(+)T cell prevalence within the tumor environment. | FENG Yutao LI Yuan MA Fen WU Enjiang CHENG Zewei ZHOU Shiling WANG Zhengtao YANG Li SUN Xun ZHANG Jiwei | 2024 | Chinese Journal of Natural Medicines2024，22，4： | 0 |
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