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11篇 您的检索式:作者名="YAO Baozhen"
    题名 作者 年代 出处 被引量
1Transit network design based on travel time reliability显示文摘Baozhen Yao Ping Hu Xiaohong Lu Junjie Gao Mingheng Zhang 2013Transportation Research Part C2013,,:2
2A method for measuring the thickness of transparent oil film on wa- ter surface with laser trigonometry 显示文摘Lu Qieni Ge Baozhen Yao Wenda 2011Opt Lasers Eng2011,49,1:1
3An improved ant colonyoptimization for vehicle routing problem显示文摘Yu Bin Yang Zhong-Zhen Yao Baozhen 2009European Journal of Operational Research2009,,196:1
4An improved ant colony opti- mization for vehicle routing problem 显示文摘Yu Bin Yang Zhangzhen Yao Baozhen 2009European Journal of Operational Research2009,196,1:1
5An Improved Ant Colony Optimization for Vehicle Routing Problem显示文摘Yu Bin Yang Zhongzhen Yao Baozhen 2009European Journal of Operational2009,196,1:1
6An improved ant Colony optimization for vehiCle routing problem显示文摘Yu B Yang Z Z Yao Baozhen 2009European Journal of Operational ResearCh2009,196,1:1
7An improved ant colony optimization for vehicle routing problem显示文摘Bin Yu Zhong-Zhen Yang Baozhen Yao 2008European Journal of Operational Research2008,,:1
8Diagnosis of Hepatocellular Carcinoma by Using Methylation Specific-PCR显示文摘To find a more sensitive and earlier diagnostic marker for hepatocellular carcinoma,methylation-profils of CpG islands in the promoter of eleven genes in hepatocellular carcinoma(HCC) carcinoma and pericarcinoma tissues from ten patients were examined by using methylation-specific PCR (MSP) method. MSP was used to detect the methylation of p16,p53,Secreted frizzled-related protein 1 (SFRP1) and SFRP2 promoters. Meanwhile,plasma alpha-fetoprotein (AFP) levels in 53 patients were also determined. The results showed that HCC was closely correlated to methylation in promoter of tumor-suppressing gene p16,p53,SFRP1 and SFRP2. The results suggest that methylation of SFRP2 promoter is possible a better marker for diagnosis of HCC than plasma Alpha-fetoprotein (AFP) levels. The false negative of SFRP1 and SFRP2 are perfectly complementary. If SFRP1 and SFRP2 were both considered as a complementary positive marker at the same time,the accurate rate for diagnosis of HCC is 100%.LIU Yanhong WU Junzhu HU Xinqian HUANG Nian YAO Baozhen GONG Zuojiong 2007Wuhan University Journal of Natural Sciences2007,12,3:1
9Transit net- work design based on travel time reliability 显示文摘YAO Baozhen HU Ping LU Xiaohong 2014Transpor- tation Research Part C: Emerging Technologies2014,43,3:1
10A method for measuring the thickness of transparent oil film on water surface using laser trigonometry显示文摘Lu Qieni Ge Baozhen Yao Wenda 2011Optics and Lasers in Engineering2011,49,1:1
11Gestational dexamethasone exposure impacts hippocampal excitatory synaptic transmission and learning and memory function with transgenerational effects显示文摘The formation of learning and memory is regulated by synaptic plasticity in hippocampal neurons.Here we explored how gestational exposure to dexamethasone,a synthetic glucocorticoid commonly used in clinical practice,has lasting effects on offspring's learning and memory.Adult offspring rats of prenatal dexamethasone exposure(PDE)displayed significant impairments in novelty recognition and spatial learning memory,with some phenotypes maintained transgenerationally.PDE impaired synaptic transmission of hippocampal excitatory neurons in offspring of F1 to F3 generations,and abnormalities of neurotransmitters and receptors would impair synaptic plasticity and lead to impaired learning and memory,but these changes failed to carry over to offspring of F5 and F7 generations.Mechanistically,altered hippocampal miR-133a-3p-SIRT1-CDK5-NR2B signaling axis in PDE multigeneration caused inhibition of excitatory synaptic transmission,which might be related to oocyte-specific high expression and transmission of miR-133a-3p.Together,PDE affects hippocampal excitatory synaptic transmission,with lasting consequences across generations,and CDK5 in offspring's peripheral blood might be used as an early-warning marker for fetal-originated learning and memory impairment.Mingcui Luo Yiwen Yi Songqiang Huang Shiyun Dai Lulu Xie Kexin Liu Shuai Zhang Tao Jiang Tingting Wang Baozhen Yao Hui Wang Dan Xu 2023Acta Pharmaceutica Sinica B2023,13,9:0
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