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    题名 作者 年代 出处 被引量
1Downregulation of thioredoxin reductase 1 expression in the substantia nigra pars compacta of Parkinson's disease mice显示文摘Because neurons are susceptible to oxidative damage and thioredoxin reductase 1 is extensively distributed in the central nervous system and has antioxidant properties,we speculated that the enzyme may be involved in the pathogenesis of Parkinson’s disease.A Parkinson’s disease model was produced by intraperitoneal injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine into C57BL/6 mice.Real-time reverse transcription-PCR,western blot analysis and colorimetric assay showed that the levels of thioredoxin reductase 1 mRNA and protein were decreased,along with a significant reduction in thioredoxin reductase activity,in the midbrain of Parkinson’s disease mice compared with normal mice.Immunohistochemical staining revealed that the number of thioredoxin reductase 1-positive neurons in the substantia nigra pars compacta of Parkinson’s disease mice was significantly decreased compared with normal mice.These experimental findings suggest that the expression of thioredoxin reductase 1 in the substantia nigra pars compacta of Parkinson’s disease mice is significantly decreased,and that the enzyme may be associated with disease onset.Zihua Liu Yuhong Jing Jie Yin Jiying Mu Tingting Yao Liping Gao 2013Neural Regeneration Research2013,8,35:2
2Preparation and characterization of porous chitosan membranes and the localization of the activity of urease immobilized on it by SEM and X-ray microanalysis显示文摘MA XIAOLI YAO ZIHUA SHI DAGANG 2005Chemical Journal on Internet2005,7,6:1
3Synthesis and characterization of Y2O3 : Eu nanopowder via EDTA complexing sol-gel process显示文摘Zhai Yongqing Yao Zihua Ding Shiwen Qiu Mande Zhai Jian 2003Materials Letters2003,,57:1
4Synthesis of PBA/PMSAN core-shell graft copolymer and its application as a processing aid for PVC显示文摘Gao Jungang Li Zhiting Yao Zihua 1995Polymer1995,36,6:1
5Total reflection angle X-ray microanalysis of microdroplets in SEM显示文摘Yao Zihua 1997Trace and Microprobe Techniques1997,15,4:1
6Grazing-exit X-ray microanalysis of Sr-doped BaTiO3 ceramic dielectric material surface显示文摘Qiu Mande Yao Zihua 2006The Proceedings of the China Association for Science and Technology2006,3,2:1
7The Electromagnetic Characteristics of UWB Signal Transmitting Through a Lossy Dielectric Slab 显示文摘CHEN Zhenqi YAO Richard and GUO Zihua 2004IEEE VTC2004,,:1
8Total reflection angle X-ray microanalysis of microdroplets in SEM显示文摘Yao zihua 1997J Trace and Microprobe Techniques1997,15,4:1
9Development of an amperometric biosensor based on glucose oxidase immobilized through silica sol-gel film onto Prussian Blue modified electrode显示文摘LI Tao YAO Zihua DING Ling 2004Sens Actuators:B2004,101,12:1
10Synthesis of CaO2 in Aqueous at Room Temperature and Its Application in Wastewater Treatment 显示文摘Zhai yongqing Ding shiwen Yao zihua et ol 2003Acta Scientiarum Naturalium Universitatis Sunyat- seni2003,42,:1
11Synthesis and Characterization of Y2O3:Eu Nanopowder via EDTA Complexing Sol-Gel Process显示文摘Zhai Yongqing Yao Zihua Ding Shiwen 2003Materials Letters2003,57,19:1
12Study on papainimmobilization on a macroporous polymer carrier显示文摘DING Liang YAO Zihua LI Tong 2003Turk J Chem2003,27,5:1
13Performance analysis of delayed acknowledgment scheme in UWB-based high-rate WPAN 显示文摘CHEN HONGYUAN GUO ZIHUA YAO R Y 2006IEEE Transactions on Vehicular Technology2006,55,2:1
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