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		题名	作者	年代	出处	被引量
	1	Differential reactivity of mouse monoclonal anti-HBs antibodies with recombinant mutant HBs antigens显示文摘AIM: To investigate the reactivity of a panel of 8 mouse anti-hepatitis B surface antigen (HBsAg) monoclonal antibodies (mAbs) using a collection of 9 recombinant HBsAg mutants with a variety of amino acid substitutions mostly located within the “a” region.METHODS: The entire HBs genes previously cloned into a mammalian expression vector were transiently transfected into COS7 cells. Two standard unmutated sequences of the ayw and adw subtypes served as controls. Secreted mutant proteins were collected and measured by three commercial diagnostic immunoassays to assess transfection efficiency. Reactivity of anti-HBs mAbs with mutated HBsAgs was determined by sandwich enzyme-linked immunosorbent assay (ELISA).RESULTS: Reactivity of anti-HBs mAbs with mutated HBsAgs revealed different patterns. While three mutants reacted strongly with all mAbs, two mutants reacted weakly with only two mAbs and the remaining proteins displayed variable degrees of reactivity towards different mAbs. Accordingly, four groups of mAbs with different but overlapping reactivity patterns could be envisaged. One group consisting of two mAbs (37C5-S7 and 35C6-S11) was found to recognize stable linear epitopes conserved in all mutants. Mutations outside the “a” determinant at positions 120 (P→S), 123(T→N) and 161(M→T) were found to affect reactivity of these mAbs.CONCLUSION: Our findings could have important implications for biophysical studies, vaccination strategies and immunotherapy of hepatitis B virus (HBV) mutants.	Azam Roohi Yaghoub Yazdani Jalal Khoshnoodi Seyed Mohammad Jazayeri William F Carman Mahmood Chamankhah Manley Rashedan Fazel Shokri	2006	World Journal of Gastroenterology2006，12，33：	4
	2	Life history andpopulation growth parameters of Neoseiulus californicus(Acari:Phytoseiidae)fed on Thrips tabaci(Thysanoptera:Thripidae)in laboratory conditions显示文摘	HASAN R YAGHOUB F KARIM K	2009	Systematic&AppliedAcarology2009，14，：	1
	3	Bottom-up effect of different host plants on Plutella xylostella (Lepidoptera: Plutellidae): A life-table study on Canola显示文摘	Mahmoud S Yaghoub F Javad K	2010	Journal of Economic Entomology2010，103，6：	1
	4	Determination of chlorophenols in water samples using simultaneous dispersive liquid-liquid microextraction and derivatization fol- lowed by gas chromatography-electron-capture detection 显示文摘	NAZIR F YAGHOUB A MOHAMMAD-REZA MH	2007	J Chromatogr A2007，1157，1：	1
	5	Cysteamine pre - treatment reduces pentylenetetrazol - induced plasticity and epileptiform discharge in the CA1 region of rat hippocampal slices显示文摘	Mohammad R Yaghoub F Saeed S	2002	Brain Res2002，955，：	1

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