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| 1 | Evaluation of patches for rotator cuff repair:A systematic review and meta-analysis based on animal studies显示文摘Based on the published animal studies,we systematically evaluated the outcomes of various materials for rotator cuff repair in animal models and the potentials of their clinical translation.74 animal studies were finally included,of which naturally derived biomaterials were applied the most widely(50.0%),rats were the most commonly used animal model(47.0%),and autologous tissue demonstrated the best outcomes in all animal models.The biomechanical properties of naturally derived biomaterials(maximum failure load:WMD 18.68[95%CI 7.71-29.66];P=0.001,and stiffness:WMD 1.30[95%CI 0.01-2.60];P=0.048)was statistically significant in the rabbit model.The rabbit model showed better outcomes even though the injury was severer compared with the rat model. | Jinwei Yang Yuhao Kang Wanlu Zhao Jia Jiang Yanbiao Jiang Bing Zhao Mingyue Jiao Bo Yuan Jinzhong Zhao Bin Ma | 2022 | Bioactive Materials2022，7，4： | 2 |
| 2 | Investigation into the Independent Metering Control Performance of a Twin Spools Valve with Switching Technology-controlled Pilot Stage显示文摘In hydraulic area,independent metering control(IMC)technology is an effective approach to improve system efficiency and control flexibility.In addition,digital hydraulic technology(DHT)has been verified as a reasonable method to optimize system dynamic performance.Integrating these two technologies into one component can combine their advantages together.However,few works focused on it.In this paper,a twin spools valve with switching technologycontrolled pilot stage(TSVSP)is presented,which applied DHT into its pilot stage while appending IMC into its main stage.Based on this prototype valve,a series of numerical and experiment analysis of its IMC performance with both simulated load and excavator boom cylinder are carried out.Results showed fast and robust performance of pressure and flow compound control with acceptable fluctuation phenomenon caused by switching technology.Rising time of flow response in excavator cylinder can be controlled within 200 ms,meanwhile,the recovery time of rod chamber pressure under suddenly changed condition is optimized within 250 ms.IMC system based on TSVSP can improve both dynamic performance and robust characteristics of the target actuator so it is practical in valve-cylinder system and can be applied in mobile machineries. | Qi Zhong Huiming Bao Yanbiao Li Haocen Hong Bin Zhang Huayong Yang | 2021 | Chinese Journal of Mechanical Engineering2021，34，5： | 1 |
| 3 | 肿瘤双自杀基因治疗系统pTRKH2-PsT/CD,pTRKH2-PsT/UPRT在厌氧婴儿双歧杆菌中的构建(英文)显示文摘Objective:We recombine the suicide gene CD,UPRT into plasmid pTRKH2 and clone the recombinant dual suicide gene therapy system into tumor-hypoxia-targeting vector Bifidobacterium infantis and characterize its function.Methods:CD gene,UPRT gene and lactic acid bacteria expression plasmid pTRKH2 were digested by restriction endonuclease BamH I and Sal I,and constructed recombinant plasmids pTRKH2/CD and pTRKH2/UPRT in E.coli.The recombinant plasmids were then transfected into Bifidobacterium Infantis by electroporation.Identification of pTRKH2/CD and pTRKH2/UPRT was processed by dual restriction endonuclease digesting and sequencing.RT-PCR and SDS-PAGE were used to examine the expression of CD and UPRT genes at RNA and protein levels.The killing effects on Melanoma B16-F10 cells by pTRKH2/CD and pTRKH2/UPRT suicide gene therapy system with 5-FC were examined by MTT assay.Results:The CD gene and UPRT gene was successfully recombined into lactic acid bacteria expression plasmid pTRKH2.After dual endonuclease digestion of plasmid purified from the positively transfected E.coli,two fragments of 6.9 Kb and 1.3 Kb were found for CD gene and two fragments of 6.9 Kb and 620 bp were found for UPRT gene.The sequencing of CD gene and UPRT gene proved consistent sequences with Genebank published data.A fragment of 1.3 Kb for CD gene and fragment of 620 bp for UPRT gene was found in recombinant Bifidobacterium by RT-PCR.A 52 KDa protein for CD gene was identified in whole-cell protein of recombinant Bifidobacterium and a 26 KDa protein for UPRT gene was identified in supernatant fluid of recombinant Bifidobacterium.The survival rate of tumor cells treated by extracts from culture of recombinant Bifidobacterium with 5-FC showed a strong killing effects of pTRKH2/CD and pTRKH2/UPRT dual suicide gene therapy system on Melanoma B16-F10 cells.Conclusion:CD gene and UPRT gene are successfully inserted into pTRKH2 and transfected into tumor-hypoxia-targeting vector Bifidobacterium Infantis.This dual suicide gene therapy system shows a high efficiency for tumor cells killing. | Zhuhua Li Peng Ye Yanbiao Yang Guangyu Ran Shuren Wang | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，7： | 1 |
| 4 | Investigation of Co_3O_4 nanorods supported Pd anode catalyst for methanol oxidation in alkaline solution显示文摘A Co3O4 nanorod supported Pd electro-catalyst for the methanol electro-oxidation(MEO) has been fabricated by the combination of hydrothermal synthesis and microwave-assisted polyol reduction processes. The crystallographic property and microstructure have been characterized using XRD, SEM and TEM. The results demonstrate that Pd nanoparticles(Pd NPs) with a narrow particle size distribution(3-5 nm) are uniformly deposited onto the surface of Co3O4 nanorods. Electrochemical measurements show that this catalyst having a larger electrochemically active surface area and a more negative onset-potential exhibits enhanced catalytic activity of 504 m A/mg Pd for MEO comparing with the Pd/C catalyst(448 m A/mg Pd). The dependency of log I against logv reveals that MEO on Pd-Co3O4 electrode is under a diffusion control.Electrochemical impedance spectroscopy(EIS) measurement agrees well with the CV results. The minimum charge transfer resistance of MEO on Pd-Co3O4 is observed at-0.05 V, which coincides with the potential of MEO peak. | Yanbiao Ren Shichao Zhang Hua Fang Xin Wei Puheng Yang | 2014 | Journal of Energy Chemistry2014，23，6： | 0 |
| 5 | Breeding and Promotion of Dunyu 107,a High-yielding and Stable-yielding Maize Variety显示文摘Dunyu 107 is a new maize variety bred by the Gansu Dunhuang Seed Group Co.,Ltd.with the self-bred excellent inbred line HA189 as the female parent and HB38 as the male parent.The variety has early maturity,tolerance to dense planting,lodging resistance,good yielding stability,good comprehensive resistance and suitability for mechanized harvesting.It passed the national approval in 2019 and has great market potential and application value. | Jikun GUO Zhibin YAN Yang XI Yanbiao YAN Xiang LI | 2020 | Asian Agricultural Research2020，12，7： | 0 |
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