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| 1 | Dual Functions of Microglia in Ischemic Stroke显示文摘Ischemic stroke is a leading cause of morbidity and mortality worldwide. Resident microglia are the principal immune cells of the brain, and the first to respond to the pathophysiological changes induced by ischemic stroke. Traditionally, it has been thought that microglial activation is deleterious in ischemic stroke, and therapies to suppress it have been intensively explored. However,increasing evidence suggests that microglial activation is also critical for neurogenesis, angiogenesis, and synaptic remodeling, thereby promoting functional recovery after cerebral ischemia. Here, we comprehensively review the dual role of microglia during the different phases of ischemic stroke, and the possible mechanisms controlling the post-ischemic activity of microglia. In addition, we discuss the dynamic interactions between microglia and other cells, such as neurons, astrocytes, oligodendrocytes,and endothelial cells within the brain parenchyma and the neurovascular unit. | Chuan Qin Luo-Qi Zhou Xiao-Tong Ma Zi-Wei Hu Sheng Yang Man Chen Dale B. Bosco Long-Jun Wu Dai-Shi Tian | 2019 | Neuroscience Bulletin2019，35，5： | 64 |
| 2 | REE geochemistry of suspended sediments from the rivers around the Yellow Sea and provenance indicators显示文摘Rare earth element (REE) compositions of the suspended sediments from the rivers around the Yellow Sea were different in that Korean river sediments (Han, Keum and Yeongsan Rivers) yield stronger fractionations than Chinese river sediments (Changjiang, Huanghe and Yalujiang), shown by obvious enrichments of LREE (light rare earth element) relative to UCC (upper continental crust). Variations of source rock compositions in the drainage basins are responsible for the differences of REE compositions between the river sediments. REE fractionation parameters including (La/Yb)UCC and (Gd/Yb)UCC as well as the ratios of La/Sc and Th/Sc can be treated as proper proxies for identifying the Chinese river sediments from those Korean river matters, and furthermore, for studying the provenances and paleoenvironmental changes of the marginal seas of China. | YANG Shouye LI Congxian C. B. Lee T. K. Na | 2003 | Chinese Science Bulletin2003，48，11： | 30 |
| 3 | RHEOCASTING OF A356 ALLOY BY LOW SUPERHEAT POURING WITH A SHEARING FIELD显示文摘A novel semi-solid slurry-making process was developed, which was a controlled nucleation and growth technique using a specially designed rotational barrel. Experimental study was undertaken to investigate the effects of pouring temperature and rotation speed of barrel on the microstructure of A356 alloy. Localized rapid cooling, combined with vigorous mixing during the initial stage of solidification enhanced wall nucleation and nuclei survival. High nuclei density combined with a much gradual cooling afterwards led to the formation of the near-ideal semi-solid slurry under a large processing window for the pouring temperature. Primary phase presented in mean equivalent diameter of 50-70μm and shape factor of 0.812-0.847, and featured zero-entrapped eutectic. | H.M. Guo X.J. Yang B. Hu | 2006 | Acta Metallurgica Sinica(English Letters)2006，19，5： | 20 |
| 4 | Analysis of ground vibrations due to underground trains by 2.5D finite/infinite element approach显示文摘The 2.5D finite/infinite element approach is adopted to study wave propagation problems caused by underground moving trains.The irregularities of the near field, including the tunnel structure and parts of the soil, are modeled by the finite elements, and the wave propagation properties of the far field extending to infinity are modeled by the infinite elements.One particular feature of the 2.5D approach is that it enables the computation of the three-dimensional response of the half-space, taking into account the load-moving effect, using only a two-dimensional profile.Although the 2.5D finite/infinite element approach shows a great advantage in studying the wave propagation caused by moving trains, attention should be given to the calculation aspects, such as the rules for mesh establishment, in order to avoid producing inaccurate or erroneous results.In this paper, some essential points for consideration in analysis are highlighted, along with techniques to enhance the speed of the calculations.All these observations should prove useful in making the 2.5D finite/infinite element approach an effective one. | Hsiao-Hui Hung Y. B. Yang | 2010 | Earthquake Engineering and Engineering Vibration2010，9，3： | 15 |
| 5 | First report of a novel abluminal groove filled biodegradable polymer rapamycin-eluting stent in de novo coronary artery disease: results of the first in man FIREHAWK trial显示文摘 | QIAN Jie XU Bo Alexandra J. Lansky YANG Yue-jin QIAO Shu-bin WU Yong-jian CHEN Jue HU Feng-huan YANG Wei-xian Gary S. Mintz Martin B. Leon GAO Run-lin | 2012 | Chinese Medical Journal2012，，6： | 14 |
| 6 | The interaction of versican with its binding partners显示文摘Versican belongs to the family of the large aggregating chondroitin sulfate proteoglycans located primarily within theextracellular matrix (ECM). Versican, like other members of its family, has unique N- and C-terminal globular regions,each with multiple motifs. A large glycosaminoglycan-binding region lies between them. This review will begin byoutlining these structures, in the context of ECM proteoglycans. The diverse binding partners afforded to versican byvirtue of its modular design will then be examined. These include ECM components, such as hyaluronan, type Icollagen, tenascin-R, fibulin-1, and -2, fibrillin-1, fibronectin, P- and L-selectins, and chemokines. Versican also binds tothe cell surface proteins CD44, integrin β1, epidermal growth factor receptor, and P-selectin glycoprotein ligand-1.These multiple interactors play important roles in cell behaviour, and the roles of versican in modulating such processesare discussed. | Yao Jiong WU David P. LA PIERRE Jin WU Albert J. YEE Burton B. YANG | 2005 | Cell Research2005，15，7： | 13 |
| 7 | Genome-wide Scan for Seed Composition Provides Insights into Soybean Quality Improvement and the Impacts of Domestication and Breeding显示文摘优秀特点的复杂基因建筑学妨碍了努力在大豆修改种子营养素。染色体宽的协会研究为种子作文被进行,包括蛋白质,油,丰满的酸,和氨基酸,用有一个高密度的 SNP 数组的 313 多样的大豆 germplasm 就职 genotyped。87 个 chromosomal 区域的一个总数被识别与种子作文被联系,解释基因变化的 8%-89% 。已知的功能的候选人基因 GmSAT1, AK-HSDH, SACPD-C,和 FAD3A,和通常认为的 MtN21 nodulin, FATB,和 steroid-5 -- 涉及 N 2 固定,氨基酸生合成,和丰满的酸新陈代谢的 reductase 在主要效果的 loci 被发现。另外的 germplasm 就职的进一步的分析显示这些主要效果的 loci 受到了驯服或现代繁殖选择,并且突变而产生之遗传的变体和分布与地理区域相关。我们也表明与种子重量有关并且到全部的蛋白质的氨基酸集中有一个不同基因基础。这帮助揭开在种子之中的复杂关系的深入的基因机制加重。因此,我们的学习不仅为大豆营养素改进提供珍贵基因和标记,份量上和品质上,而且进在驯服期间优秀、引起的大豆的改变的提议卓见。 | Jiaoping Zhang Xianzhi Wang Yaming Lu Siddhi J. Bhusal Qijian Song Perry B. Cregan Yang Yen Michael Brown Guo-Liang Jiang | 2018 | Molecular Plant2018，11，3： | 12 |
| 8 | Evaluating the Effect of Tillage on Carbon Sequestration Using the Minimum Detectable Difference Concept显示文摘Three long-term field trials in humid regions of Canada and the USA were used to evaluate the influence of soil depth and sample numbers on soil organic carbon (SOC) sequestration in no-tillage (NT) and moldboard plow (MP) corn (Zea mays L.) and soybean (Glycine max L.) production systems. The first trial was conducted on a Maryhill silt loam (Typic Hapludalf) at Elora, Ontario, Canada, the second on a Brookston clay loam (Typic Argiaquoll) at Woodslee, Ontario, Canada, and the third on a Thorp silt loam (Argiaquic Argialboll) at Urbana, Illinois, USA. No-tillage led to significantly higher SOC concentrations in the top 5 cm compared to MP at all 3 sites. However, NT resulted in significantly lower SOC in sub-surface soils as compared to MP at Woodslee (10-20 cm, P = 0.01) and Urbana (20-30 cm, P < 0.10). No-tillage had significantly more SOC storage than MP at the Elora site (3.3 Mg C ha-1) and at the Woodslee site (6.2 Mg C ha-1) on an equivalent mass basis (1350 Mg ha-1 soil equivalent mass). Similarly, NT had greater SOC storage than MP at the Urbana site (2.7 Mg C ha-1) on an equivalent mass basis of 675 Mg ha-1 soil. However, these differences disappeared when the entire plow layer was evaluated for both the Woodslee and Urbana sites as a result of the higher SOC concentrations in MP than in NT at depth. Using the minimum detectable difference technique, we observed that up to 1500 soil sample per tillage treatment comparison will have to be collected and analyzed for the Elora and Woodslee sites and over 40 soil samples per tillage treatment comparison for the Urbana to statistically separate significant differences in the SOC contents of sub-plow depth soils. Therefore, it is impracticable, and at the least prohibitively expensive, to detect tillage-induced differences in soil C beyond the plow layer in various soils. | X. M. YANG C. F. DRURY M. M. WANDER B. D. KAY | 2008 | Pedosphere2008，18，4： | 11 |
| 9 | SIMULATION ON HEATING PROCESS IN ULTRASONIC WELDING OF PLASTICS显示文摘The energy conversion during ultrasonic plastic welding is analyzed on the basis of the theory of vis- coelastic mechanics,.The temperature field and the temperature change of the ABS specimen with ener- gy director during ultrasonic welding is simulated with finite element method(FEM). In the simu- lation process,the melting of the energy energy is also considered. The calculation results are in good agreement with the temperature measurement results, which proves that the simulation results are reli- able. | S. Q. Yang Z. Dong J. C. Yan and J. B. Ju( National Key Laboratory of Advanced Welding Production Technology, HIT, Harbin 150001, China) | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，1： | 10 |
| 10 | Nature:研究鉴定出蛋白Nlrp9b抵抗轮状病毒感染机制显示文摘轮状病毒(rotavirus)是婴儿和儿童罹患肠胃炎和腹泻的一种最为常见的原因,每年导致全世界大约21.5万人死亡。它是高度传染性的和潜在致命性的。这种病毒特异性地感染宿主小肠中的肠上皮细胞,并且已进化出抵抗干扰素和NF-KB信号的策略来躲避免疫系统,这就提出一个问题:其他的宿主因子是否参与肠道粘膜中的抗病毒反应。不过,针对体内(特别是通过NLR炎性体)检测和限制肠道病毒的机制,人们知之甚少。 | Shu Zhu, Zheng Wei, Noah W. Palm, Yi Yang, Hua Yu, Hua-Bing Li, Geng Wang, Xuqiu Lei, Marcel R. de Zoete, Jun Zhao, Yunjiang Zheng, Haiwei Chen, Liang Shan, Richard A. Flavell Siyuan Ding, Ningguo Feng, Harry B. Greenberg Siyuan Ding, Harry B. Greenberg Penghua Wang, Yujiao Zhao Wen Pan, Jun Lu Jun Zhao, Yuval Kluger Kellie A. Jurado, Clara Abraham, Erol Fikrig Erol Fikrig, Richard A. Flavell | 2017 | 现代生物医学进展2017，17，27： | 10 |
| 11 | Gly(82)Ser polymorphism of the receptor for advanced glycation end products is associated with an increased risk of gastric cancer in a Chinese population显示文摘 | Gu, H.J. Yang, L. Sun, Q. M. Zhou, B. Tang, N. P. Cong, R. H. Zeng, Y. Wang, B. | 2008 | 南京医科大学学报(自然科学版)2008，28，9： | 9 |
| 12 | Efficacy and safety of FIREHAWK abluminal groove filled biodegradable polymer sirolimus-eluting stents for the treatment of long coronary lesions: nine-month angiographic and one-year clinical results from TARGET I trial lona cohort显示文摘 | XU Bo GAO Run-lin ZHANG Rui-yan WANG Hai-chang LI Zhan-quan YANG Yue-jin MA Chang-sheng HAN Ya-ling Alexandra J. Lansky HUO Yong LI Wei Martin B. Leon | 2013 | Chinese Medical Journal2013，，6： | 8 |
| 13 | Catalysis of Dissolved and Adsorbed Iron in Soil Suspension for Chromium(VI) Reduction by Sulfide显示文摘The kinetics of Cr(VI) reduction by sulfide in soil suspensions with various pHs, soil compositions, and Fe(II) concentrations was examined using batch anaerobic experimental systems at constant temperature. The results showed that the reaction rate of Cr(VI) reduction was in the order of red soil < yellow-brown soil < chernozem and was proportional to the concentration of HCl-extractable iron in the soils. Dissolved and adsorbed iron in soil suspensions played an important role in accelerating Cr(VI) reduction. The reaction involved in the Cr(VI) reduction by Fe(II) to produce Fe(III), which was reduced to Fe(II) again by sulfide, could represent the catalytic pathway until about 70% of the initially present Cr(VI) was reduced. The catalysis occurred because the one-step reduction of Cr(VI) by sulfide was slower than the two-step process consisting of rapid Cr(VI) reduction by Fe(II) followed by Fe(III) reduction by sulfide. In essence, Fe(II)/Fe(III) species shuttle electrons from sulfide to Cr(VI), facilitating the reaction. The effect of iron, however, could be completely blocked by adding a strong Fe(II)-complexing ligand, 1,10-phenanthroline, to the soil suspensions. In all the experiments, initial sulfide concentration was much higher than initial Cr(VI) concentration. The plots of lnc[Cr(VI)] versus reaction time were linear up to approximately 70% of Cr(VI) reduction, suggesting a first-order reaction kinetics with respect to Cr(VI). Elemental sulfur, the product of sulfide oxidation, was found to accelerate Cr(VI) reduction at a later stage of the reaction, resulting in deviation from linearity for the lnc[Cr(VI)] versus time plots. | LAN Ye-Qing YANG Jun-Xiang B. DENG | 2006 | Pedosphere2006，16，5： | 7 |
| 14 | Relationships between Regional Indian Summer Monsoon Rainfall and Eurasian Snow Cover显示文摘RelationshipsbetweenRegionalIndianSummerMonsoonRainfallandEurasianSnowCoverB.Parthasarathy(IndianinstituteofTropicalMeteorolo... | B. Parthasarathy Song Yang | 1995 | Advances in Atmospheric Sciences1995，12，2： | 7 |
| 15 | Latest Wuchiapingian to Earliest Triassic Conodont Zones and δ13 Ccarb Isotope Excursions from Deep-Water Sections in Western Hubei Province, South China显示文摘Deep-water facies sections have advantages of recording complete information across the Permian-Triassic boundary(PTB). Here we present a detailed study on the conodont biostratigraphy and carbon isotope profile ranges from the Wuchiapingian-Changhsingian boundary(WCB) to the PTB of two deep-water facies sections at Zhuqiao and Shiligou in the Middle Yangtze region, western Hubei, South China. Fifteen species and three genera are identified. Eight conodont zones are recognized which in ascending order are the Clarkina orientalis, C. wangi, C. subcarinata, C. changxingensis, C. yini, C. meishanensis, Hindeodus parvus and Isarcicella isarcica zones. The onset of deposition of the deep-water siliceous strata of Dalong Formation in western Hubei began in the Late Wuchiapingian and persisted to the Late Changhsingian. Carbon isotope negative excursions occur near both the WCB and PTB in both sections. The WCB δ13 Ccarb negative excursion is in the C. orientalis and C. wangi zones. The PTB δ13 Ccarb negative excursion began in the C. yini Zone and extended to the I. isarcica Zone. The absence of several Changhsingian zones may indicate the difficulty of extracting conodonts from siliceous strata or the presence of an intra-Changhsingian hiatus. | Bo Yang Hanxiao Li Paul B. Wignall Haishui Jiang Zhijun Niu Qian Ye Qiong Wu Xulong Lai | 2019 | Journal of Earth Science2019，30，5： | 5 |
| 16 | The Characterization of Sputtered Zr-Ge-N Thin Films as Diffusion Barriers Between Copper and Silicon显示文摘The main purpose of the present micro-structural analysis by transmission electron microscopy(TEM)and X-ray diffraction(XRD)was to investigate whether amorphous Zr-Ge-N films are a potential candidate as a diffusion barrier for Cu wiring used in Si devices.The Zr-Ge-N films were prepared by a radio frequency(RF)reactive magnetron sputter-deposition technique using N2 and Ar mixed gas,and the film structure was found to be sensitive to the gas flow ratio of N2 vs.Ar during sputtering.Polycrystalline Zr-Ge-N films were obtained when the N2/(Ar+N2)ratio was smaller than 0.2 and amorphous-like Zr-Ge-N films were obtained when the ratio was larger than 0.3.Diffusion barrier test was performed by annealing the Cu/Zr-Ge-N/Si film stack under Ar atmosphere.The deposited Zr-Ge-N(C)films remained amorphous even after high temperature annealing.The Cu diffusion profile in the film was assessed by the Auger electron spectroscopy(AES).The results indicate that Cu diffusion was minimal in amorphous Zr-Ge-N(C)films even at high annealing temperatures of 800℃. | Yang, J. J. Liu, B. Liao, X. D. Jiao, G. H. Xu, K. W. | 2012 | 稀有金属材料与工程2012，41，S1： | 5 |
| 17 | Termination of polymorphic ventricular tachycardia storm by catheter ablation in a patient with cardiomyopathy induced by incessant idiopathic left ventricular tachycardia显示文摘 | Shan, Q. J. Chen, M. L. Xu, D. X. Zou, J. G. Yang, B. Chen, C. Cao, K. J. | 2007 | 南京医科大学学报(自然科学版)2007，27，10： | 5 |
| 18 | Catalytic Properties of Pt Cluster-Decorated CeO2 Nanostructures显示文摘磅的一致的簇在 capping-agent-free CeO2 nanooctahedra 和 nanorods 使用电子横梁(电子横梁) 的表面上被扔了蒸发。磅 nanocluster 层的范围能被调整电子横梁蒸发时间控制。产生电子横梁在 CeO2 表面上蒸发了磅 nanocluster 层有在磅和 CeO2 之间的干净表面和干净接口。CeO2 nanocrystals 的二种类型上的磅的不同生长行为被观察,与 CeO2 nanooctahedra 上的磅的取向附生的生长和 CeO2 nanorods 上的磅的随机的生长。CeO2 nanocrystals 的二种不同类型上的磅簇的结构被为模型反应把他们用作催化剂学习了并且比较。加氢反应的结果清楚地在两催化剂显示出磅簇的干净、类似的化学表面。这些催化剂的支持依赖者活动被公司氧化表明。因为氧空缺的更高的集中, Pt/CeO2 nanorods 在 CeO2 nanorods 与 Pt/CeO2 nanooctahedra 相比显示出许多更高的活动。除氢作用反应的结构依赖者选择显示 CeO2 nanorods 和 nanooctahedra 上的磅的结构是不同的。因为金属免职行为被强壮的金属金属氧化物相互作用调制, Thes 差别产生。 | Lin Feng Dat Tien Hoang Chia-Kuang Tsung Wenyu Huang Sylvia Hsiao-Yun Lo Jennifer B. Wood Hungta Wang dinyao Tang Peidong Yang | 2011 | Nano Research2011，4，1： | 5 |
| 19 | Phosphate limitation of phytoplankton growth in the Changjiang Estuary显示文摘Laboratory experiments of bioassay with Pltaeodaetytum tricornutum, Chatoceros didymus, Chaetoreros calcitraus and Heterogtoea sp. sampled from the Changjiang Estuary in spring and summer, 1986, indicated that both N and P limit phytoplankton growth in the medium with N : P ranged between 8-30, and N limits phytoplankton production in the medium with N: P<8, while P is the limitary nutrient in the N : P>30. Generally, N : P in the Changjiang Estuary waters is 2 times higher than Redfield ratio. The bioassay experiments with high N : P water samples collected from Changjiang Estuary show that phytoplankton production is limited by P. Phytopiankton appears to give priority to the uptake of P at all periods of time. And the optimum N:P for phytoplankton growth is determined to be 18. | Hu Minghui, Yang Yiping, Xu Chunling and P. J. Harrison Oceanography Department of Xiamen University, Xiamen, ChinaSub-bureau of East China Sea, State Oceanic Administration, Shanghai, ChinaOceanography Department, U. B. C. , Canada | 1990 | Acta Oceanologica Sinica1990，9，3： | 4 |
| 20 | A Bayesian Network Approach for Offshore Risk Analysis Through Linguistic Variables显示文摘This paper presents a new approach for offshore risk analysis that is capable of dealing with linguistic probabilities in Bayesian networks(BNs).In this paper,linguistic probabilities are used to describe occurrence likelihood of hazardous events that may cause possible accidents in offshore operations.In order to use fuzzy information,an f-weighted valuation function is proposed to transform linguistic judgements into crisp probability distributions which can be easily put into a BN to model causal relationships among risk factors.The use of linguistic variables makes it easier for human experts to express their knowledge,and the transformation of linguistic judgements into crisp probabilities can significantly save the cost of computation,modifying and maintaining a BN model.The flexibility of the method allows for multiple forms of information to be used to quantify model relationships,including formally assessed expert opinion when quantitative data are lacking,or when only qualitative or vague statements can be made.The model is a modular representation of uncertain knowledge caused due to randomness,vagueness and ignorance.This makes the risk analysis of offshore engineering systems more functional and easier in many assessment contexts.Specifically,the proposed f-weighted valuation function takes into account not only the dominating values,but also the α-level values that are ignored by conventional valuation methods.A case study of the collision risk between a Floating Production,Storage and Off-loading(FPSO) unit and the authorised vessels due to human elements during operation is used to illustrate the application of the proposed model. | Ren J. Wang J. Jenkinson I. Xu D. L. Yang J. B. | 2007 | China Ocean Engineering2007，21，3： | 4 |
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