|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Isolation and characterization of bipotent liver progenitor cells from adult mouse显示文摘 | Li WL Su J Yao YC Tao XR Yan YB Yu HY Wang XM Li JX Yang YJ Lau JT HuYP | 2006 | 中国生物学文摘2006，20，5： | 26 |
| 2 | Cloning and expression of MXR7 gene in human HCC tissue显示文摘AIM To clone and identify the whole cDNA ofMXR7 gene and to find out its expression inhuman HCC,and normal tissues.METHODS The DNA primers were designed andsynthesized according to the whole cDNAsequence of MXR? gene.The cDNA of humanHCC was taken as the template while the cDNA ofMXR7 gene was synthesized by polymerasechain reaction(PCR).Recombinant DNAconforming to reading frame was constructed byconnecting purified PCR product of the cDNA ofMXR? gene with expression vector pGEX-5X-1 offusion protein.The plasmid MXRT/pGEX-5X-1was identified by sequencing.Using 32p labeledMXR? cDNA as probe,MXR7 mRNA expressionwas detected by Northern blot analysis in 12different human normal tissues,7 preoperativelyuntreated non-liver tumor tissues,30preoperatively untreated HCC,theparacancerous liver tissues and 12 normal livertissues samples.RESULTS Restriction enzyme and sequenceanalysis confirmed that the insertion sequence invector pGEX-5X-1 was the same as the cDNAsequence of MXR7 gene.Northern blot analysisshowed no expression of MXR? mRNA in 12 kindsof normal human tissues including liver,7 tumortissues in other sites and 12 normal livertissues,the frequencies of MXR7 mRNA expression in HCC and paracancerous livertissues were 76.6% and 13.3%,respectively.The frequency of MXR7 mRNA expression in HCCwithout elevation of serum AFP and in HCC<5cm was 90%(9/10)and 83.3%(5/6),respectively.CONCLUSION MXR7 mRNA is highly expressedin human HCC,which is specific and occurs at anearly stage of HCC,suggesting MXR7 mRNA canbe a tumor biomarker for HCC.The detection ofMXR7 mRNA expression in the biopsied livertissue is helpful in discovering early subclinicalliver cancer in those with negative serum AFP. | Zhou XP Wang HY Yang GS Chen ZJ Li BA Wu MC | 2000 | World Journal of Gastroenterology2000，6，1： | 23 |
| 3 | Byakangelicin induces cytochrome P450 3A4 expression via transactivation of pregnane X receptors in human hepatocytes显示文摘 | Yang, JA Luan, XF Gui, HY Yan, P Yang, DF Song, XL Liu, W Hu, G Yah, BF | 2011 | 南京医科大学学报(自然科学版)2011，31，4： | 8 |
| 4 | Heat shock proteins reduce alpha-synuclein aggregation induced by MPP+ in SK-N-SH cells.显示文摘 | Fan GH Zhou HY Yang H Chert SD | 2006 | 中国生物学文摘2006，20，9： | 6 |
| 5 | NEOARCTIN A FROM ARCTIUM LAPPA L显示文摘NEOARCTIN A FROM ARCTIUM LAPPAL ￥HaiYanWANG1andJunShanYANG(1InstituteofMedicinalPlantDevelopment,ChineseAcademyofMedicalScien... | Wang, HY Yang, JS | 1995 | Chinese Chemical Letters1995，6，3： | 6 |
| 6 | 一种新的皮肤活力检测方法的研究显示文摘目的探索一种四氮唑盐法(WST1)对皮肤活力检测及其对储存异体皮质量鉴定的效果。方法以四氮唑盐法对猪皮片和人皮片活力进行了实验性检测。对试剂的剂量、反应时间、皮片厚度,皮片面积、皮片重量等实验条件的选择进行了研究。结果以直径为10mm,厚度为03mm的小皮片,试剂剂量为20μl,在37℃下孵化3小时为最佳实验条件。结论WST1试剂可用于皮肤细胞活力及异体皮质量的检测。 | 贾晓明 Yang,HY | 1999 | 中华外科杂志1999，37，3： | 5 |
| 7 | TLR-3启动子区功能性基因多态性与骨关节炎的相关性:两阶段病例对照研究显示文摘骨关节炎(osteoarthritis,OA)被认为是多因素疾病,目前有关其遗传因素的研究涉及了遗传方式及基因组的潜在突变位置等。最近的报道显示,Toll样受体(toll-like receptor,TLR)家族与OA的发生发展关系密切。单核苷酸多态性(single nucleotide polymorphisms,SNPs)在TLR基因中普遍存在,并对TLR功能产生影响。前期研究证实,TLR-9基因的(-1486T/C)启动子多态性与末期膝OA有关,而作为同属于核内体TLR、均以病原相关分子方式来识别病毒和细菌核酸的TLR-3,7,8,其功能性基因多态性是否与中国汉族人群膝OA有关,是本研究的主要目的。 | Yang HY Lee HS Lee CH 白朝晖 章莹 | 2013 | 中国骨科临床与基础研究杂志2013，5，6： | 3 |
| 8 | Intraspinal transplantation of CD34+ human umbilical cord blood cells after spinal cord hemisection injury improves functional recovery in adult rats显示文摘 | Zhao,ZM Li,HJ Liu,HY Lu,SH Yang,RC Zhang,QJ Han,ZC | 2005 | 中国生物学文摘2005，19，3： | 2 |
| 9 | Amniotic membrane transplantation for ocular surface reconstruction in patients with chemical and thermal burns 显示文摘 | Shimazaki J Yang HY Tsubota K | 1997 | Ophthalmology1997，104，12： | 2 |
| 10 | Cloning and identification of an angiostatic molecule IP-10/crg-2显示文摘AIM To obtain human and murine cDNAsencoding IFN--y inducible protein 10 (lP--10) andcytokine responsive gene--2 (Crg-2).METHODS The encoding genes of lP-10 and Crg2 were amplified by RT--PCR from Cultured humanfibroblast cells and Balb/ c mouse liver treatedby IFN-y and TNF-a, respectively, and clonedinto plasmids of PUC19 and PGEM3Zf(+ ).RESULTS The nucleotide sequences ot theamplified DNA were confirmed by endonucleasesdigestion and sequencing.CONCLUSION Recombinant lP-10/ crg--2 geneclones with 306 hp and 314 hp inserts wereestablished for further research on biologicalactivities and ligands of hiP-10/mCrg--2. | Liu ZG Yang JH An HZ Wang HY He FT Han ZY Han Y Wu HP Xiao B Fan DM | 1999 | World Journal of Gastroenterology1999，5，3： | 2 |
| 11 | A Facile Procedure for the oxidative Coupling of 2-Naphthol and 2-Naphthalenethiol in Solid State显示文摘The oxidation of 2-naphthol and 2-naphthalenethiol to 1,1’ -bi-2-naphthol and bis-2naphthyl disulfide respectively has been carried out in excellent yields in solid state in the presence of Fe3+-montmorillonite or alumina-supported FeCl3. | Li, TS Zhang, ZH Yang, F Duan, HY Li, BZ Tewari, BB | 1998 | Chinese Chemical Letters1998，9，7： | 2 |
| 12 | One-year soy isuflavone sup- plementation prevents early postmenopausal bone loss but withou a dose - dependent effect 显示文摘 | Huang HY Yang HP Yang HT | 2006 | Journal of Nutritional Biochemistry2006，17，8： | 1 |
| 13 | Amnoitic membrane transplantation for ocular surface reconstruction in patients with chemical and thermal burns显示文摘 | Yang HY Tsubota K | 1997 | Ophthalmology1997，104，12： | 1 |
| 14 | Amniotic membrane transplantation for ocular surface reconstruction in patients with chemical and thermal burns显示文摘 | Shimazaki J Yang HY Tsubota K | 1997 | Ophthalmology1997，104，12： | 1 |
| 15 | Monoclonal T cell proliferation and plaque instability in acute coronary syndromes显示文摘 | Liuzzo G Goronzy JJ Yang HY | 2000 | Circulation2000，101，25： | 1 |
| 16 | A note on the causal relationship between energy and GDP in Taiwan显示文摘 | YANG HY | 2000 | Energy Economics2000，22，3： | 1 |
| 17 | Early identification of lepto- spirosis as an ignored cause of muhiple organ dysfunction syndrome 显示文摘 | Yang HY Yen TH Lin CY | 2012 | Shock2012，38，1： | 1 |
| 18 | Amniotic membrane transplatation for ocular surface reconstmtion in patients with chemical and thermal bums显示文摘 | Swimazaki J Yang HY Tsubota K | 1997 | Ophthalmology1997，104，11： | 1 |
| 19 | The p73 gene is less involved in the development but involved in the progression of neuroblastoma 显示文摘 | Piao HY Chen YZ | 2000 | Int J Mol Med2000，5，4： | 1 |
| 20 | Refractory hypertension and anemia in end-stage renal disease:An unusual manifestation of Kimura's disease显示文摘 | Yang HY Lin CC | 2003 | Ren Fail2003，5，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员