|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Technological development and engineering applications of novel steel-concrete composite structures显示文摘In view of China's development trend of green building and building industrialization,based on the emerging requirements of the structural engineering community,the development and proposition of novel resourcesaving high-performance steel-concrete composite structural systems with adequate safety and durability has become a kernel development trend in structural engineering.This paper provides a state of the art review of China's cutting-edge research and technologies in steel-concrete composite structures in recent years,including the building engineering,the bridge engineering and the special engineering.This paper summarizes the technical principles and applications of the long-span bi-directional composite structures,the long-span composite transfer structures,the comprehensive crack control technique based on uplift-restricted and slip-permitted (URSP)connectors,the steel plate concrete composite (SPCC)strengthen technique,and the innovative composite joints.By improving and revising traditional structure types, the comprehensive superiority of steel-concrete composite structures is well elicited.The research results also indicate that the high-performance steel-concrete composite structures have a promising popularizing prospect in the future. | Jianguo NIE Jiaji WANG Shuangke GOU Yaoyu ZHU Jiansheng FAN | 2019 | Frontiers of Structural and Civil Engineering2019，13，1： | 9 |
| 2 | Clerodenoids A-F:C-ring Aromatized and/or Rearranged Abietane Diterpenoids from Clerodendrum chinense var.simplex显示文摘Main observation and conclusion As part of our continuing efforts toward the discovery of the biologically active diterpenoids from medicinal plants,six new C-ring aromatized abietane diterpenoids,clerodenoids A-F(1-6),were isolated from Clerodendrum chinense. | Jingjing Qi Yan Zhang Qunfang Liu Hongchun Liu Yaoyue Fan Jianmin Yue | 2021 | Chinese Journal of Chemistry2021，39，7： | 1 |
| 3 | A novel long-term intravenous combined with local treatment with human amnion-derived mesenchymal stem cells for a multidisciplinary rescued uremic calciphylaxis patient and the underlying mechanism显示文摘Calciphylaxis is a rare disease characterized histologically by microvessel calcification and microthrombosis,with high mortality and no proven therapy.Here,we reported a severe uremic calciphylaxis patient with progressive skin ischemia,large areas of painful malodorous ulcers,and mummified legs.Because of the worsening symptoms and signs refractory to conventional therapies,treatment with human amnion-derived mesenchymal stem cells(hAMSCs)was approved.Preclinical release inspections of hAMSCs,efficacy,and safety assessment,including cytokine secretory ability,immunocompetence,tumorigenicity,and genetics analysis in vitro,were introduced.We further performed acute and long-term hAMSC toxicity evaluations in C57BL/6 mice and rats,abnormal immune response tests in C57BL/6 mice,and tumorigenicity tests in neonatal Balbc-nu nude mice.After the preclinical research,the patient was treated with hAMSCs by intravenous and local intramuscular injection and external supernatant application to the ulcers.When followed up to 15 months,the blood-based markers of bone and mineral metabolism improved,with skin soft tissue regeneration and a more favorable profile of peripheral blood mononuclear cells.Skin biopsy after 1-month treatment showed vascular regeneration with mature noncalcified vessels within the dermis,and 20 months later,the re-epithelialization restored the integrity of the damaged site.No infusion or local treatment-related adverse events occurred.Thus,this novel long-term intravenous combined with local treatment with hAMSCs warrants further investigation as a potential regenerative treatment for uremic calciphylaxis due to effects of inhibiting vascular calcification,stimulating angiogenesis and myogenesis,anti-inflammatory and immune modulation,multidifferentiation,re-epithelialization,and restoration of integrity. | Lianju Qin Jing Zhang Yujie Xiao Kang Liu Yugui Cui Fangyan Xu Wenkai Ren Yanggang Yuan Chunyan Jiang Song Ning Xiaoxue Ye Ming Zeng Hanyang Qian Anning Bian Fan Li Guang Yang Shaowen Tang Zhihong Zhang Juncheng Dai Jing Guo Qiang Wang Bin Sun Yifei Ge Chun Ouyang Xueqiang Xu Jing Wang Yaoyu Huang Hongqing Cui Jing Zhou Meilian Wang Zhonglan Su Yan Lu Di Wu Jingping Shi Wei Liu Li Dong Yinbing Pan Baiqiao Zhao Ying Cui Xueyan Gao Zhanhui Gao Xiang Ma Aiqin Chen Jie Wang Meng Cao Qian Cui Li Chen Feng Chen Youjia Yu Qiang Ji Zhiwei Zhang Mufeng Gu Xiaojun Zhuang Xiaolin Lv Hui Wang Yanyan Pan Ling Wang Xianrong Xu Jing Zhao Xiuqin Wang Cuiping Liu Ningxia Liang Changying Xing Jiayin Liu Ningning Wang | 2022 | Journal of Molecular Cell Biology2022，14，2： | 1 |
| 4 | Fe_(3)O_(4) Nanoparticle‑modified Multi‑walled Carbon Nanotubes for the Determination of Synthetic Pyrethroids in Human Blood显示文摘In this study,a sensitive and rapid magnetic solid‑phase microextraction(MSPE)procedure based on Fe_(3)O_(4) nanoparticle‑modified,multi‑walled carbon nanotubes combined with a gas chromatography/electron capture detector(GC/ECD)was developed to quantify pyrethroids in human blood samples.This study compared liquid-liquid extraction and solid‑phase extraction methods and found that the MSPE‑GC/ECD method had many advantages,such as high recovery rate,high extraction efficiency,high detection sensitivity,low limit of detection,and simple operation.It can meet the actual requirements for the determination of synthetic pyrethroids in human blood. | Cui Yanhua Shen Weidong Yang Fan Pan Yaoyue Zhang Suling Yao Weixuan | 2019 | Journal of Forensic Science and Medicine2019，5，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员