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| 1 | 急诊经皮冠状动脉介入治疗与远端血栓保护装置PercuSurge Guardwire联合治疗急性心肌梗死(英文)显示文摘目的 评价远端血栓保护装置PercuSurgeGuardwire在急性心肌梗死 (AMI)的高危急诊经皮冠状动脉介入 (PCI)治疗中预防远端血栓栓塞并发症的临床疗效及安全性。方法 92例AMI患者为研究对象 ,其中 4 7例在急诊PCI过程中联合应用PercuSurgeGuardwire装置(PercuSurge组 ) ,平均年龄 (6 1 4± 7 1)岁 ;另 4 5例进行常规无PercuSurgeGuardwire保护的急诊PCI (对照组 ) ,平均年龄 (6 4 9± 8 3)岁。比较两组急诊PCI术后即刻冠状动脉TIMI血流及院内、 30天主要心脏不良事件发生率。结果 全部病例均成功植入血管支架并放置PercuSurgeGuardwire保护装置。平均阻滞球囊直径 (4 5± 0 5 )mm ,平均阻滞时间 (8 7± 5 9)min。PercuSurge组术后TIMI 3级血流率显著高于对照组 (95 74与 86 6 7% ,P <0 0 5 ) ,无血流事件发生率显著降低 (0 %与 6 6 7% ,P <0 0 5 )。并发症包括 :血管夹层 1例 (2 13% ) ,远端小血管血栓栓塞 1例 (2 13% )。随访全部患者 ,PercuSurge组院内及 30天心脏不良事件发生率均显著低于对照组 (分别为 2 13%与13 33% ,2 13%与 8 89% ,P值均小于 0 0 5 )。结论 联合应用PercuSurgeGuarwire远端保护装置在AMI患者的急诊PCI过程中可安全有效地预防远端血栓栓塞并发症的发生 。 | 李浪 刘唐威 Tan Huay Cheem Lim Yean Teng | 2004 | 中华急诊医学杂志2004，13，9： | 12 |
| 2 | 远端保护装置FilterWire EX^(TM)在冠状动脉旁路移植术后大隐静脉桥病变介入治疗中的临床效果显示文摘目的 远端血栓栓塞是冠状动脉旁路移植术后大隐静脉桥的介入治疗过程中常见的并发症,本研究在大隐静脉桥病变的介入治疗中应用新颖的FilterWire EXTM远端保护装置,评价其临床疗效与安全性。方法 选择73例冠状动脉旁路移植术后大隐静脉桥病变患者为研究对象。其中39例患者在FiherWire EXTM的保护下行介入治疗(FilterWire EXTM组),而另34例患者进行无保护的常规介入治疗(对照组)。比较两组患者介入治疗前后的FIMI血流,院内及30 d心脏不良事件发生率。结果 Filter-Wire EXTM在全部病例均成功释放。FiherWire EXTM组经皮冠状动脉介入治疗后TIMI3级血流发生率显著高于对照组(89.74%比76.47%,P<0.05),“无血流”(TIMI 0/1级血流)或“慢血流”(TIMI 2级血流)发生率显著低于对照组(分别为2.56%比8.82%及7.69%比14.70%,P<0.05),院内及30 d心脏不良事件发生率均显著降低(7.69%比17.65%及5.13%比14.71%,P<0.05);未见与装置有关的并发症。结论 在大隐静脉桥病变的介入治疗中联合应用FilterWire EXTM远端保护装置可安全有效,简便易行地预防远端血栓栓塞并发症的发生,显著降低患者院内及30 d心脏不良事件发生率。 | 李浪 Tan Huay Cheem Teo Swee Guan Lim Yean Teng | 2004 | 中华心血管病杂志2004，32，7： | 4 |
| 3 | Feasibility and accuracy of coronary imaging in elderly patients using the 64-row multi-detector computed tomography: a correlation study with conventional coronary angiography显示文摘Background Elderly patients generally have higher occurrence of coronary calcification, increased heart rate and difficulty with prolonged breath-holding. The aim of our study was to investigate the feasibility and accuracy of using 64-row multi-detector computed tomography (MDCT) in the assessment of coronary artery stenoses in elderly patients. Methods One hundred and fifty two patients with suspected or known coronary artery disease were divided into 4 groups according to their age (Group A: 40-49 years,n=34; Group B: 50-59 years, n=57; Group C: 60-69 years, n=48; Group D: 70 years and above; n=13). Coronary CT angiography (CTA) using a 64-row MDCT was performed and the findings were compared with that of conventional coronary angiography (CCA).Using axial images, multi-planar reconstructions (MPR) and maximum intensity projections (MIP), coronary segments of lumen diameter = 1.5mm were analyzed for the presence of significant stenosis (= 50% ). Results Percentages of poor image quality from coronary CTA preventing reliable correlations with CCA were 21%, 14%, 19% and 62% in Groups A to D respectively. Patients in Group D had significantly higher calcium scores compared with the other groups (P<0.001). In patients where CTA images were of acceptable quality, percentages of accurate correlations with CCA were 89.8%, 93.4%, 86.6% and 78.0% for Groups A to D respectively.There were no significant difference in serum creatinine, heart rate and contrast volume between the 4 groups. Conclusions The 64-row MDCT coronary angiography was less accurate and feasible for patients aged 70 years or above due to heavy coronary calcification and inability to perform a satisfactory breath-hold. However, a high diagnostic accuracy with the MDCT is possible in patients aged less than 70 years. | Chee Khoon LIEW Sze Piaw CHIN Tiong Kiam ONG Seyfarth Tobias Yean Yip FONG Choon Kiat ANG Houng Bang LIEW Rapaee ANNUAR Kui Hian SIM | 2006 | Journal of Geriatric Cardiology2006，3，1： | 4 |
| 4 | Diabetic muscle infarction in end-stage renal disease: A scoping review on epidemiology, diagnosis and treatment显示文摘Diabetic muscle infarction(DMI) refers to spontaneous ischemic necrosis of skeletal muscle among people with diabetes mellitus, unrelated to arterial occlusion. People with DMI may have coexisting end-stage renal disease(ESRD) but little is known about its epidemiology and clinical outcomes in this setting. This scoping review seeks to investigate the characteristics, clinical features, diagnostic evaluation, management and outcomes of DMI among people with ESRD. Electronic database (Pub Med/MEDLINE, CINAHL, SCOPUS and and EMBASE) searches were conducted for ('diabetic muscle infarction' or 'diabetic myonecrosis') and('chronic kidney disease' or 'renal impairment' or 'dialysis' or 'renal replacement therapy' or 'kidney transplant ') from January 1980 to June 2017. Relevant cases from reviewed bibliographies in reports retrieved were also included. Data were extracted in a standardized form. A total of 24 publications with 41 patients who have ESRD were included. The mean age at the time of presentation with DMI was 44.2 years. Type 2 diabetes was present in 53.7% of patients while type 1 in 41.5%. In this cohort, 60.1% were receiving hemodialysis, 21% on peritoneal dialysis and 12.2% had kidney transplantation. The proximal lower limb musculature was the most commonly affected site. Muscle pain and swelling were the most frequent manifestation on presentation. Magnetic resonance imaging (MRI) provided the most specific findings for DMI. Laboratory investigation findings are usually non-specific. Non-surgical therapy is usually used in the management of DMI. Short-term prognosis of DMI is good but recurrence occurred in 43.9%. DMI is an uncommon complication in patients with diabetes mellitus, including those affected by ESRD. In comparison with unselected patients with DMI, the characteristics and outcomes of those with ESRD are generally similar. DMI may also occur inkidney transplant recipients, including pancreas-kidney transplantation. MRI is the most useful diagnostic investigation. Non-surgical treatment involving analgesia, optimization of glycemic control and initial bed rest can help to improve recovery rate. However, recurrence of DMI is relatively frequent. | Tuck Yean Yong Kareeann Sok Fun Khow | 2018 | World Journal of Nephrology2018，7，2： | 4 |
| 5 | Decomposition and Reformulation of Banxia Baizhu Tianma Decoction:A Vasodilatory Approach显示文摘Objective To decompose and reformulate Banxia Baizhu Tianma Decoction(BBT) in order to optimize its ratio for vasodilatory effect.The fingerprints of these six component herbs were also studied via Tri-step FTIR analysis.Methods The herbal components of BBT were extracted separately with different solvents,such as 95%ethanol,50%ethanol,and distilled water.The vasodilatory effect of the extracts was studied using the in vitro pre-contracted aortic ring model.Among these extracts,the water extracts of Pinellia ternata[PT(W)]and Citri reticulatae[CR(W)],50%ethanol extracts of Castrodia elata[GE(50)]and Clycyrrhiza uralensis[GU(50)],and 95%ethanol extracts of Atractylodes macrocephala[AM(E)],and Poria cocos[PC(E)]were selected for the orthogonal stimulus-response compatibility group study due to their high effectiveness in vasodilation.Results The best combination ratio(G2) was GE(50),GU(50),AM(E),PC(E),CR(W),and PT(W) at EC_0,EC_5,EC_5,EC_5,EC_5,and EC_5,with EC_(50) of(0.06 ± 0.01) mg/mL.Comparison between the vasodilatory effects of extracts derived from G2 and BBT were also studied.From the results,the 50%ethanol extract following G2 ratio was found to be most potent extract with the highest vasodilatory effect compared with other extracts derived from G2 or BBT,with EC_(50) of(0.05 ±0.005) mg/mL.Conclusion The optimum ratio and appropriate extraction method for the new BBT formulae are obtained.G2 is determined as the best formulae with the highest potency in producing the vasodilatory effect on isolated rat aortic rings.The results obtained suggest that 50%ethanol is found to be the best solvent to extract the vasoactive compounds of G2 in order to exhibit the highest efficacy of vasodilatory effect. | Chu Shan Tan Yean Chun Loh Yung Sing Ch'ng Mariam Ahmad Mohd.Zaini Asmawi Mun Fei Yam | 2017 | Chinese Herbal Medicines2017，9，2： | 3 |
| 6 | 紫杉醇洗脱支架在冠心病介入治疗中的临床应用显示文摘目的观察紫杉醇洗脱支架(商品名TAXUS)治疗冠心病的疗效及安全性。方法选择77例冠心病患者,包括36例稳定型心绞痛、40例急性冠状动脉综合征、1例急性心肌梗死,对其92处病变(1处A型病变.91处B型和C型病变)植入92枚TAXUS。于术后住院期间、术后30日及12个月检查手术部位再狭窄及心脏不良事件。结果全部病例成功植入TAXUS;术前靶病变狭窄程度为(77±10)%,术后残余狭窄程度为(6.2±0.8)%;目标血管的参考直径及长度分别为(3.6±0.4)mm和(15.0±2.0)mm,植入支架的平均直径及长度分别为(3.2±0.4)mm和(24±15)mm。术后30日发生支架内再狭窄1例,术后第4日亚急性血栓形成1例,6个月在观察终点发生支架边缘再狭窄1例。再狭窄发生率2.6%,心脏不良事件发生率3.9%,靶血管血运重建率3.3%。结论TAXUS可有效地预防冠心病介入治疗术后再狭窄,心脏不良事件发生率低。 | 李浪 Lim Yean Teng Tan Huay Cheem 刘唐威 | 2005 | 岭南心血管病杂志2005，11，3： | 2 |
| 7 | An Investigation of Direct Condensation of Steam Jet in Subcooled Water显示文摘 | MOON H C YEAN S K JEE W P | 1996 | Heat Mass Transfer1996，23，7： | 1 |
| 8 | A pentaplex PCR assay for the rapid detection of methicillinresistant Staphylococcus aureus and PantonValentine Leuocidin显示文摘 | AlTalib H Yean C Y AlKhateeb A | 2009 | BMC Microbiol2009，9，： | 1 |
| 9 | A critical review on the recent progress of synthesizing techniques and fabrication of TiO 2 -based nanotubes photocatalysts显示文摘 | Yean Ling Pang Steven Lim Hwai Chyuan Ong Wen Tong Chong | 2014 | Applied Catalysis A, General2014，，： | 1 |
| 10 | Adsorption of arsenic to magnetite nanoparticles: effect of particle concentration, pH, ionic strength, and temperature 显示文摘 | Shipley H J Yean S Kan A T | 2009 | Environmental Toxicology and Chemistry2009，28，3： | 1 |
| 11 | Increased serum levels of interleukin - 6 and yon Willenbrand Factor in early phase of a- cute coronary sYndrome in a young and multiethnic Malaysian pop- ulation 显示文摘 | Wen Ni Tiong Alan Yean Yip Fong | 2012 | Heart Asia2012，4，： | 1 |
| 12 | A numerical study of the Hampson-type miniature Joule-Thomson cryocooler 显示文摘 | Tui Tong Chua Wang Xiaolin Hwee Yean Teo | 2006 | International Journal of Heat and Mass Transfer2006，49，： | 1 |
| 13 | Sons, Daughters, and Inter-Generational Support in Taiwan 显示文摘 | Lee Yean Ju William Parish and Robert Willis | 1994 | American Journal of Sociology1994，99，4： | 1 |
| 14 | Oral paricalcitol versus oral calcitriol in continuous ambulatory peritoneal dialysis patients with secondary hyperparathyroidism显示文摘 | Jamaluddin EJ Gafor AH Yean LC | 2014 | Clin Exp Nephrol2014，18，3： | 1 |
| 15 | Molecular weights of lignosulphonate and carbohydrate leached from sulfite chemimechanical pulp显示文摘 | WILLIS J W YEAN W Q GORING D A L | 1987 | Journal of Wood Chemistry Technology1987，7，2： | 1 |
| 16 | Hemoglobin variants detec- ted by hemoglobin Alc (HbAlc) analysis and the effects on HbAle measurements显示文摘 | Nasir NM Thevarajah M Yean CY | 2010 | Int J Diabetes Dev Ctries2010，30，2： | 1 |
| 17 | Anxiety and Depression in Patients with Coronary Heart Disease: A Study in a Tertiary flospital显示文摘 | 8o Siew Eng Loo Chee Yean Srijit Das | 2011 | Iran J Med Sci2011，36，： | 1 |
| 18 | Inhibition of tumor invasion of smooth muscle cell layers by recombinant human metalloproteinase inhibitor显示文摘 | Declerck YV Yean TD Chan D | 1991 | Cancer Res1991，51，8： | 1 |
| 19 | Model for Fostering Trust and Building Relationships in China' s Construction Industry 显示文摘 | Xiao - Hua Jin Florence Yean Yng Ling | 2005 | Journal of Construction Engineering and Management2005，131，11： | 1 |
| 20 | Effect of magnetite particle size on adsorption and desorption of arsenite and arsenate显示文摘 | YEAN S CONG L YAVUZ C T | 2005 | Materials Research2005，20，12： | 1 |
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