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| 1 | Associating liver partition and portal vein ligation for staged hepatectomy: the current role and development显示文摘BACKGROUND: Associating liver partition and portal vein ligation for staged hepatectomy(ALPPS) has recently been developed to induce rapid liver hypertrophy and reduce posthepatectomy liver failure in patients with insufficient future liver remnant(FLR). ALPPS is still considered to be in an early developmental phase because surgical indications and techniques have not been standardized. This article aimed to review the current role and future developments of ALPPS.DATA SOURCES: Studies were identified by searching MEDLINE and Pub Med for articles from January 2007 to October 2016 using the keywords 'associating liver partition and portal vein ligation for staged hepatectomy' and 'ALPPS'. Additional papers were identified by a manual search of references from key articles.RESULTS: ALPPS induces more hypertrophy of the FLR in less time than portal vein embolization or portal vein ligation.The benefits of ALPPS include rapid hypertrophy 47%-110% of the liver over a median of 6-16.4 days, and 95%-100% completion rate of the second stage of ALPPS. The main criticisms of ALPPS are centered on its high morbidity and mortality rates. Morbidity rates after ALPPS have been reported to be 15.3%-100%, with ≥ the Clavien-Dindo grade III morbidity of 13.6%-44%. Mortality rates have been reported to be 0%-29%.The important questions to ask even if oncologic long-term results are acceptable are: whether the gain in quality and quantity of life can be off balance by the substantial risks of morbidity and mortality, and whether stimulation of rapid liver hypertrophy also accelerates rapid tumor progression and spread. Up till now, the documentations of the ALPPS procedure come mainly from case series, and most of these series include heterogeneous groups of malignancies. The numbers are also too small to separately evaluate survival for different tumor etiologies.CONCLUSIONS: Currently, knowledge on ALPPS is limited, and prospective randomized studies are lacking. From the reported preliminary results, safety of the ALPPS procedure remains questionable. ALPPS should only be used in experienced, high-volume hepatobiliary centers. | Wan Yee Lau Eric CH Lai Stephanie HY Lau | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，1： | 16 |
| 2 | Improving PBLs in the International Medical University: defining the 'good' PBL facilitator显示文摘 | Yee HY Radhakrishnan A Ponnudurai G | 2006 | Med Teach2006，28，6： | 1 |
| 3 | Papillomas of the external ear canal: report of ten cases in Chinese patients with HPV in situ hybridization显示文摘 | Wang S Yee H Wen HY | 2009 | Head Neck Path&2009，5，3： | 1 |
| 4 | Inhibitory effects of luteolin isolated from Ixeris sonchifolia Hance on the proliferation of HepG2 human hepatocellular carcinoma ceils显示文摘 | Yee SB Lee JH Chung HY | 2003 | Archives of Pharmacal Research2003，26，2： | 1 |
| 5 | A new filter papermethod to measure capillary blood lead level in children 显示文摘 | Srivuthana K Yee HY Bhambhani K | 1996 | ArchPediatr Adolesc Med1996，150，5： | 1 |
| 6 | Cap polyposis: A rare cause of rectal bleeding in children显示文摘AIM: To evaluate the clinicopathological features and treatment outcomes of cap polyposis in the pediatric population. METHODS: All pediatric patients with histologically proven diagnosis of cap polyposis were identified from our endoscopy and histology database over a 12 year period from 2000-2012 at our tertiary pediatric center, KK Women's and Children's Hospital in Singapore. The case records of these patients were retrospectively reviewed. The demographics, clinical course, laboratory results, endoscopic and histopathological features, treatments, and outcomes were analyzed. The study protocol was approved by the hospital institutional review board. The histological slides were reviewed by a pediatric histopathologist to confirm the diagnosis of cap polyposis. RESULTS: Eleven patients were diagnosed with cap polyposis. The median patient age was 13 years (range 5-17 years); the sample included 7 males and 4 females. All of the patients presented with bloody stools. Seven patients (63%) had constipation, while 4 patients (36%) had diarrhea. All of the patients underwent colonoscopy and polypectomies (excluding 1 patient who refused polypectomy). The macroscopic findings were of polypoid lesions covered by fibrinopurulent exudates with normal intervening mucosa. The rectum was the most common involvement site (n = 9, 82%), followed by the rectosigmoid colon (n = 3, 18%). Five (45%) patients had fewer than 5 polyps, and 6 patients (65%) had multiple polyps. Histological examination of these polyps showed surface ulcerations with a cap of fibrin inflammatory exudate. Four (80%) patients with fewer than 5 polyps had complete resolution of symptoms following the polypectomy. One patient who did not consent to the polypectomy had resolution of symptoms after being treated with sulphasalazine. All 6 patients with multiple polyps experienced recurrence of bloody stools on follow-up (mean = 28 mo). CONCLUSION: Cap polyposis is a rare and underrecognised cause of rectal bleeding in children. Our study has characterized the disease phenotype and treatment outcomes in a pediatric cohort. | Jia Hui Li May Ying Leong Kong Boo Phua Yee Low Ajmal Kader Veena Logarajah Lin Yin Ong Joyce HY Chua Christina Ong | 2013 | World Journal of Gastroenterology2013，19，26： | 1 |
| 7 | Management of bile duct injury after laparoscopic cholecystectomy:a review 显示文摘 | Wan Yee Lau Eric CH Lai Stephanie HY Lau | 2010 | ANZ J Surg2010，80，1： | 1 |
| 8 | Management of bile duet injury after laparoscopic choleeysteetomy: a review 显示文摘 | Wan Yee Lau Eric CH Lai Stephanie HY Lau | 2010 | ANZ J Surg2010，80，1： | 1 |
| 9 | An improved capillary blood-filter paper-graphite furnace atomic absorption spectrometric method for lead screening 显示文摘 | Yee HY Holtrop TG | 1997 | J Anal Toxicol1997，21，2： | 1 |
| 10 | A new filter paper method to measure capillary blood lead level in children 显示文摘 | Srivuthana K Yee HY Bhambhani K | 1996 | Arch pediatr Adolesc Med1996，150，5： | 1 |
| 11 | Inhibitory effects of lutsolin isolated from ixexissonchifolia hance on the proliferation of HepG2 human hepatocellular carcinoma cells显示文摘 | Yee SB Lee JH Chung HY | 2003 | Arch Pharm Res2003，26，2： | 1 |
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