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| 1 | Interaction of five anthraquinones from rhubarb with human organic anion transporter 1 (SLC22A6) and 3 (SLC22A8) and drug–drug interaction in rats显示文摘 | Liping Ma Lei Zhao Haihong Hu Yahong Qin Yicong Bian Huidi Jiang Hui Zhou Lushan Yu Su Zeng | 2014 | Journal of Ethnopharmacology2014，，3： | 1 |
| 2 | Comparison of enhancement techniques based on neural networks for attenuated voice signal captured by flexible vibration sensors on throats显示文摘Wearable flexible sensors attached on the neck have been developed to measure the vibration of vocal cords during speech.However,highfrequency attenuation caused by the frequency response of the flexible sensors and absorption of high-frequency sound by the skin are obstacles to the practical application of these sensors in speech capture based on bone conduction.In this paper,speech enhancement techniques for enhancing the intelligibility of sensor signals are developed and compared.Four kinds of speech enhancement algorithms based on a fully connected neural network(FCNN),a long short-term memory(LSTM),a bidirectional long short-term memory(BLSTM),and a convolutional-recurrent neural network(CRNN)are adopted to enhance the sensor signals,and their performance after deployment on four kinds of edge and cloud platforms is also investigated.Experimental results show that the BLSTM performs best in improving speech quality,but is poorest with regard to hardware deployment.It improves short-time objective intelligibility(STOI)by 0.18 to nearly 0.80,which corresponds to a good intelligibility level,but it introduces latency as well as being a large model.The CRNN,which improves STOI to about 0.75,ranks second among the four neural networks.It is also the only model that is able to achieves real-time processing with all four hardware platforms,demonstrating its great potential for deployment on mobile platforms.To the best of our knowledge,this is one of the first trials to systematically and specifically develop processing techniques for bone-conduction speed signals captured by flexible sensors.The results demonstrate the possibility of realizing a wearable lightweight speech collection system based on flexible vibration sensors and real-time speech enhancement to compensate for high-frequency attenuation. | Shenghan Gao Changyan Zheng Yicong Zhao Ziyue Wu Jiao Li Xian Huang | 2022 | Nanotechnology and Precision Engineering2022，5，1： | 0 |
| 3 | ESTIMATION OF ROCK-AGGREGATE VOLUME BASED ON PCA AND LM-OPTIMIZED NEURAL NETWORK显示文摘In granule processing industries,acquisition of particle size and shape parameters is a common procedure,and volumetric measurement is of great importance in dealing with particle sizing and gradation. To eradicate the major drawbacks with manual gauge,this paper proposes an optical approach using Back Propagation (BP) neural network to estimate the particle volume based on the two-Dimensional (2D) image information. To achieve the better network efficiency and structure simplicity,Principal Component Analysis (PCA) is adopted to reduce the dimensions of network inputs. To overcome the shortcomings of generic BP network for being slow to converge and vulnerable to being trapped in local minimum,Levenberg-Marquardt (LM) algorithm is applied to achieve a higher speed and a lower error rate. The real particle data is utilized in training and testing the presented network. The experimental result suggests that the proposed neural network is capable of estimating aggregate volume with satisfactory precision and superior to the generic BP network in terms of performance capacity. | Zhao Pan Chen Ken Wang Yicong Zhang Yun | 2009 | Journal of Electronics(China)2009，26，6： | 0 |
| 4 | How light affect the magnetotactic behavior and reproduction of ellipsoidal multicellular magnetoglobules?显示文摘Magnetotactic bacteria(MTB)synthesize intracellular magnetic organelles,magnetosomes,which consist of magnetic crystals that are enveloped in a membrane.Magnetosomes are organized into a chain(s)and confer on cells a magnetic dipolar moment.This magnetic property allows MTB cells to align and swim along geomagnetic field lines,a movement referred to as magnetotaxis.Some MTB species change their swim direction in response to illumination by UV,violet and blue light.Here we analyzed the polarity of morphology,magnetism,and motion in Mediterranean multicellular magnetotactic prokaryotes,also called,magnetoglobules or MMP.The magnetoglobules were assembled from 60-80 cells into an asymmetric ellipsoidal morphology with a relative narrow and large end.They swam dominantly northward,parallel to the direction of the magnetic field,with the narrow-end as the leading side.In response to a reversal in the direction of the magnetic field,they aligned quickly along the magnetic field lines and kept swimming northward.Interestingly,under constant illumination,385-nm UV light,magnetoglobules changed their swimming direction southward anti-parallel to the direction of the magnetic field,with the large-end as the leading side.The change from a northward to southward direction occurred along with an increase of swimming speed.A minimum of 35-mW/cm^(2) irradiance of UV light was sufficient to trigger the swimming re-orientation.UV radiation also triggered the unidirectional division of magnetoglobules.Together these results revealed a coordination of the polarity of magnetoglobule morphology,magnetic moment,and swimming orientation,in response to magnetic and optical stimuli.The UV triggered the reversal of magnetotaxis and magnetoglobule division indicating the ecological significance of light for multicellular magnetotactic prokaryotes. | Xinxin QIAN Yicong ZHAO Claire-Lise SANTINI Hongmiao PAN Tian XIAO Haitao CHEN Tao SONG Jinhua LI Francois ALBERTO Sophie BRUSTLEIN Long-Fei WU | 2021 | Journal of Oceanology and Limnology2021，39，6： | 0 |
| 5 | Characterization and diversity of magnetotactic bacteria from sediments of Caroline Seamount in the Western Pacific Ocean显示文摘Magnetotactic bacteria(MTB)are a group of microorganisms capable of orientating and swimming along magnetic fields because they contain intracellular biomineralized magnetosomes composed of magnetite(Fe 3 O 4)or/and greigite(Fe_(3)S_(4)).They are ubiquitous in freshwater,brackish,and marine habitats,and are cosmopolitan in distribution.However,knowledge of their occurrence and distribution in seamount ecosystems is limited.We investigated the diversity and distribution of MTB in the Caroline Seamount(CM4).The abundance of living MTB in 12 stations in depth varying from 90 to 1545 m was 1.1×10^(3)-43.7×10^(3) inds./dm 3.Despite diverse shapes of MTB observed,magnetotactic cocci were the dominant morphotype and could be categorized into two types:1)typical cocci that appeared to have peritrichous fl agella;and 2)those characterized by having a drop-shaped form and one bundle of fl agella located at the thin/narrow end of the cell.Transmission electron microscopy(TEM)analysis revealed that the magnetosomes formed by those magnetotactic cocci are magnetite(Fe 3 O 4)with octahedral crystal habit.A total of 41 operational taxonomic units(OTUs)of putative MTB(2702 reads)were acquired from nine stations,based on high-throughput sequencing.Of these,40 OTUs belonged to the Proteobacteria phylum and one belonged to the Nitrospirae phylum.We found apparent connectivity between the MTB populations on the Caroline and Kexue(Science in Chinese)seamounts,although the diversity of MTB on Caroline was much richer than on the Kexue Seamount.Our results imply that the unique topography of seamounts and other as-yet unclear environmental factors could lead to evolution of different fl agella arrangements in magnetotactic cocci,and the occurrence of octahedral magnetite magnetosomes. | Kaixuan CUI Wenyan ZHANG Jia LIU Cong XU Yicong ZHAO Si CHEN Hongmiao PAN Tian XIAO Long-Fei WU | 2021 | Journal of Oceanology and Limnology2021，39，6： | 0 |
| 6 | Observations on a magnetotactic bacteria-grazing ciliate in sediment from the intertidal zone of Huiquan Bay,China显示文摘Magnetotactic bacteria(MTB)are a group of prokaryotes having the ability to orient and swim along geomagnetic field lines because they contain intracellular magnetosomes that are synthesized through a biomineralization process.Magnetosomes have recently also been found in unicellular eukaryotes,which are referred to as magnetically responsive protists(MRPs).The magnetosomes have three origins in MRPs.In this study,we characterized a MTB-grazing ciliated MRP that was magnetically collected from intertidal sediment of Huiquan Bay,Qingdao,China.Based on 18S rRNA gene sequence analysis,the ciliated MRP was tentatively identified as Uronemella parafi lificum HQ.Using transmission electron microscopy,we observed that magnetosomes having 2-3 shapes were randomly distributed within this ciliate.Energydispersive X-ray spectroscopy and high-resolution transmission electron microscopy images of the magnetosomes were consistent with them being composed of magnetite.Magnetosomes having the same shape and mineral composition were also detected in MTB that occurred in the same environment as the ciliated MRP.Statistical analysis showed that the size and shape of the magnetosomes in the ciliated MRP were similar to those in MTB.The results suggest that this ciliated MRP can graze,ingest,and digest various types of MTB.It is certainly worth noting that this is the first record of MRPs in Asian aquatic sediment and suggesting they might be widely distributed.These results also support the assertion that MRPs probably contribute to the ecological cycles of iron,and expand possibilities for research into the mechanism of magnetoreception in eukaryotes. | Si CHEN Kaixuan CUI Wenyan ZHANG Yicong ZHAO Tian XIAO Hongmiao PAN Wuchang ZHANG Long-Fei WU | 2021 | Journal of Oceanology and Limnology2021，39，6： | 0 |
| 7 | Trajectory optimisation in electrical discharge machining of three-dimensional curved and twisted channels显示文摘Numerical control electrical discharge machining(NC EDM) is one of the most widely used machining technologies for manufacturing a closed blisk flow path, particularly for three-dimensional(3D) curved and twisted flow channels. In this process, tool electrode design and machining trajectory planning are the key factors affecting machining accessibility and efficiency. Herein, to reduce the difficulty in designing the electrode and its motion path in the closed curved and twisted channels, a heuristic search hybrid optimisation strategy based on channel grids is adopted to realise the initial electrode trajectory design search and optimised size reduction. By transferring the trajectory optimisation constraints from the complex free-form surface to numbered grids, the search is found to be more orderly and accurate. The two trajectory indicators, namely argument angle and minimum distance, are analysed separately for the optimised results of the adaptive learning particle swarm optimisation algorithm, demonstrating that they can meet the actual processing requirements.Experimental results of NC EDM indicate that the motion path generated by this design method can meet the machining requirements of 3D curved and twisted flow channels. | Jianshe ZHAO Yicong QIU Jian YUAN Chao LIU | 2022 | Chinese Journal of Aeronautics2022，35，4： | 0 |
| 8 | Stereodivergent Pd/Cu Catalysis for Asymmetric Desymmetric Alkylation of Allylic Geminal Dicarboxylates显示文摘AstereodivergentPd/Cucatalyst systemforasymmetric desymmetric alkylation of allylic geminal dicarboxylates has been developed,which was successfully applied to the asymmetric synthesis of β-hydroxycarbonylmotifs bearing a versatile carbon-carbon double bond in an enantio-and diastereodivergent manner.A wide scope of substrates including challenging alkylsubstituted,2-substituted,and3,3′-disubstitutedallylic species are compatible with this catalytic system,delivering the substituted products in high to excellent yieldsandwith excellent diastereo-(upto>20:1 dr)and enantioselectivities(up to>99%ee).Furthermore,the mechanism of this dual Pd/Cu catalytic system including:(1)the desymmetrization process ofgeminal dicarboxylates;(2)the origin of regioselectivity(branched or linear);(3)the enantio-and diastereoselectivity observed by changing the combinations of two chiral metal catalysts,have been carefully investigated by theoretical calculations. | Xiaohong Huo Ling Zhao Yicong Luo Yue Wu Yuwen Sun Guanlin Li Tatiana Gridneva Jiacheng Zhang Yong Ye Wanbin Zhang | 2022 | CCS Chemistry2022，4，5： | 0 |
| 9 | AGGREGATE IMAGE BASED TEXTURE IDENTIFICATION USING GRAY LEVEL CO-OCCURRENCE PROBABILITY AND BP NEURAL NETWORK显示文摘Classifying the texture of granules in 2D images has aroused manifold research atten-tion for its technical challenges in image processing areas.This letter presents an aggregate texture identification approach by jointly using Gray Level Co-occurrence Probability(GLCP) and BP neural network techniques.First, up to 8 GLCP-associated texture feature parameters are defined and computed, and these consequent parameters next serve as the inputs feeding to the BP neural network to calculate the similarity to any of given aggregate texture type.A finite number of aggregate images of 3 kinds, with each containing specific type of mineral particles, are put to the identification test, experimentally proving the feasibility and robustness of the proposed method. | Chen Ken Wang Yicong Zhao Pan Larry E. Banta Zhao Xuemei | 2009 | Journal of Electronics(China)2009，26，3： | 0 |
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