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| 1 | Efficacy and safety of a novel anti-HER2 therapeutic antibody RC48 in patients with HER2-overexpressing,locally advanced or metastatic gastric or gastroesophageal junction cancer:a single-arm phase II study显示文摘Background:Current treatment options for human epidermal growth factor receptor 2(HER2)-overexpressing gastric cancer at third-line have shown limited clinical benefit.Further,there is no specific treatment for HER2 immunohistochemistry(IHC)2+and fluorescence in-situ hybridization-negative patients.Here,we report the efficacy and safety of a novel anti-HER2 antibody RC48 for patients with HER2-overexpressing,advanced gastric or gastroesophageal junction cancer.Methods:Patients with HER2-overexpressing(IHC 2+or 3+),locally advanced or metastatic gastric or gastroesophageal junction cancer who were under at least second-line therapy were eligible and received RC482.5 mg/kg alone every 2 weeks.The primary endpoint was the objective response rate(ORR)assessed by an independent review committee.Secondary endpoints included progressionfree survival(PFS),overall survival(OS),duration of response,time to progression,disease control rate,and safety.Results:Of 179 patients screened,125 were eligible and received RC48 treatment.The ORR was 24.8%(95%confidence interval[CI]:17.5%-33.3%).The median PFS and OS were 4.1 months(95%CI:3.7-4.9 months)and 7.9 months(95%CI:6.7-9.9 months),respectively.The most frequently reported adverse events were decreased white blood cell count(53.6%),asthenia(53.6%),hair loss(53.6%),decreased neutrophil count(52.0%),anemia(49.6%),and increased aspartate aminotransferase level(43.2%).Serious adverse events(SAEs)occurred in 45(36.0%)patients,and RC48-related SAEs were mainly decreased neutrophil count(3.2%).Seven patients had adverse events that led to death were not RC48-related.Conclusions:RC48 showed promising activity with manageable safety,suggesting potential application in patients with HER2-overexpressing,advanced gastric or gastroesophageal junction cancer who have previously received at least two lines of chemotherapy. | Zhi Peng Tianshu Liu Jia Wei Airong Wang Yifu He Liuzhong Yang Xizhi Zhang Nanfeng Fan Suxia Luo Zhen Li Kangsheng Gu Jianwei Lu Jianming Xu Qingxia Fan Ruihua Xu Liangming Zhang Enxiao Li Yuping Sun Guohua Yu Chunmei Bai Yong Liu Jiangzheng Zeng Jieer Ying Xinjun Liang Nong Xu Chao Gao Yongqian Shu Dong Ma Guanghai Dai Shengmian Li Ting Deng Yuehong Cui Jianmin Fang Yi Ba Lin Shen | 2021 | Cancer Communications2021，41，11： | 29 |
| 2 | Self-template synthesis of double-layered porous nanotubes with spatially separated photoredox surfaces for efficient photocatalytic hydrogen production显示文摘Improving charge carriers separation to achieve high photoconversion efficiency in heterogeneous photocatalysts is highly desirable.Herein,heterostructured ZnS@CdS double-layered porous nanotubes(PNTs),in which the spatially separated reduction and oxidation reaction sites lie on the outer and inner shell,respectively,are fabricated through a robust self-template conversion strategy.After selective photo-deposition of Ni and CoO_x as dual cocatalysts,Ni nanoparticles as electron collectors and reduction reaction sites are loaded on the outer shell,while CoO_x nanoparticles as hole collectors and oxidation reaction sites are loaded on the inner shells.As a result,a novel CoO_x/ZnS@CdS/Ni photocatalyst is obtained and shows high visible-light-driven photocatalytic hydrogen production activity owing to the synergistic effect of self-template-derived thin mesoporous heterojunctions and photo-depositionderived spatially separated dual cocatalysts,which can significantly provide driving force for the ordered transfer of photogenerated electrons and holes toward opposite direction and promote the surface catalytic reaction.Additionally,the facile strategy can be broadened to the preparation of CoO_x/ZnSe@CdSe/NiPNTs with enhanced photocatalytic activity. | Yani Xin Yi Huang Kui Lin Yifu Yu Bin Zhang | 2018 | Science Bulletin2018，63，10： | 9 |
| 3 | "One Belt and One Road" and Free Trade Zones--China's New Opening-up Initiatives显示文摘一条带和带道路和自由贸易地区是策略发展了响应的二瓷器新洞起来改变了国内、国际的情形。这些策略的实现能向中国提供一个更健全的市场经济系统和更好的外部环境。进一步发展成一个高收入国家不能仅仅帮助中国,而且便于另外的发展中的国家的工业化和现代化。 | Justin Yifu Lin | 2015 | Frontiers of Economics in China-Selected Publications from Chinese Universities2015，10，4： | 9 |
| 4 | Wet-chemistry synthesis of cobalt carbide nanoparticles as highly active and stable electrocatalyst for hydrogen evolution reaction显示文摘转变金属碳化物(TMC ) nanomaterials 正在答应选择到磅,并且广泛地为电气化学的氢进化反应被用作异构的 electrocatalysts (她的) 。在这个工作,综合的导致溴化物的湿化学的策略公司 2 C nanoparticles (NP ) 被开发。如此的 NP 展出了高 electrocatalytic 活动(= 为 j = 的 181 mV 10 | Siwei Li Ce Yang Zhen Yin Hanjun Yang Yifu Chen Lili Lin Mengzhu Li Weizhen Li Gang HU Ding Ma | 2017 | Nano Research2017，10，4： | 7 |
| 5 | Seventy Years of Economic Development: A Review from the Angle of New Structural Economics显示文摘This review paper provides a new narrative by combing through the experiences of structural transformation among developing countries and discussing the roles of government and market in different contexts.Country performance has been influenced by the prevailing development thinking:the structuralism in the 1950s-1970s,which stresses an active government's role to overcome market failures for industrialization,and the neoliberalism in the 1980s-present,which advocates for eliminating government failures to build up a well-functioning market.We find that almost all countries failing by following structuralism in their industrialization and neoliberalism in their transition to a market economy,and the few countries successful in catching up have a few characteristics that go against the prevailing structuralism and neoliberalism.The new structural economics,generated from the experiences of successful East Asian economies and proposing active facilitating roles of government in a market economy to remove market failures,will gain traction and take root. | Justin Yifu Lin Yan Wang | 2020 | China & World Economy2020，28，4： | 7 |
| 6 | Visualization Research and Application of Water Quality Monitoring Data Based on ECharts显示文摘Water resources are one of the basic resources for human survival,and water protection has been becoming a major problem for countries around the world.However,most of the traditional water quality monitoring research work is still concerned with the collection of water quality indicators,and ignored the analysis of water quality monitoring data and its value.In this paper,by adopting Laravel and AdminTE framework,we introduced how to design and implement a water quality data visualization platform based on Baidu ECharts.Through the deployed water quality sensor,the collected water quality indicator data is transmitted to the big data processing platform that deployed on Tencent Cloud in real time through the 4G network.The collected monitoring data is analyzed,and the processing result is visualized by Baidu ECharts.The test results showed that the designed system could run well and will provide decision support for water resource protection. | Yifu Sheng Weida Chen Huan Wen Haijun Lin Jianjun Zhang | 2020 | Journal on Big Data2020，2，1： | 3 |
| 7 | Rural Informal Taxation in China:Historical Evolution and an Analytic Framework显示文摘The present paper examines the historical evolution of China's rural taxation system from the pre-reform period to the late 1990s. We propose that because of information asymmetry between the upper-level and the lower-level governments, local governments had to be granted some informal tax autonomy to fulfill the upper-level policy mandates. This easily led to excessive local informal taxation on farmers. As market liberalization of the grain sector progressed, the low-cost tax instruments implemented through the traditional approach of implicit taxation gradually eroded. Local governments in agricultural regions had to resort to informal fees collected directly from individual rural households while the more industrialized regions shifted to non-agricultural taxes that are less costly in terms of tax collection. Hence, political tension between farmers and local governments in agriculture- based regions emerged and rural tax reform became necessary. | Justin Yifu Lin Mingxing Liu | 2007 | China & World Economy2007，15，3： | 3 |
| 8 | Factors Affecting the Outlook for Medium-term to Long-term Growth in China显示文摘中国在时期 1978-2015 上完成了将近 10% 的平均 GDP 生长。然而,生长的如此的高水平多长罐头被支撑,特别当人均的 GDP 层次到达了中间收入的地位,和正常时,当他们成熟,经济的趋势是慢下来?这份报纸在中国为真实 GDP 生长在决定因素和眼界上考察最近的文学并且探讨一些关键问题,包括识别能支持在有利条件下面的继续的强壮的生长,以及冒险可能引起生长突然掉落的因素的供应方面因素。纸用一个生长财务框架考察生长的供应方面决定因素,并且也估计驾驶潜在的生长的主要要求方面因素,包括出口,大写的形成和家庭消费。 | Justin Yifu Lin Guanghua Wan Peter J. Morgan | 2016 | China & World Economy2016，24，5： | 3 |
| 9 | China's Growth Deceleration: Causes and Future Growth Prospect显示文摘China's growth decelerated substantially after 2010. This paper argues that the main cause for the deceleration is external and cyclical, China has a potential growth rate of 8%, the economy has good investment opportunities and resources, and China is likely to achieve a medium-high growth rate of around 6.5% in the coming years. The paper also examines the various structural reforms that can help China to release its growth potential and complete the transition to a well-functioning market economy. | Justin Yifu Lin | 2019 | Frontiers of Economics in China-Selected Publications from Chinese Universities2019，14，1： | 2 |
| 10 | Policy burden, privatization and soft budget constraint显示文摘 | Justin Yifu Lin Zhiyun Li | 2007 | Journal of Comparative Economics2007，，1： | 2 |
| 11 | Policy Burdens, Accountability and Soft Budget Constraint显示文摘 | Lin Justin Yifu Tan Guofu | 1999 | American Economic Review1999，89，2： | 1 |
| 12 | An Economics Theory of Institutional Change: Induced and Imposed Change 显示文摘 | Lin Justin Yifu | 1989 | Cato Journal1989，9，01： | 1 |
| 13 | Rural reform and agriculture growth in china显示文摘 | Justin Yifu Lin | 1992 | The American Economic Keview1992，，82： | 1 |
| 14 | Rural Reforms and Agricultur- al Growth in China显示文摘 | Justin Yifu Lin | 1992 | The American Economic Review1992，82，1： | 1 |
| 15 | Rural Reforms and Agricultural Growth in China显示文摘 | Justin Yifu Lin | 1992 | The American Economic Review1992，，82： | 1 |
| 16 | Industrial Dynamics, Endowment Structure and Economic Growth 显示文摘 | Ju Jiandong Lin Justin Yifu Wang Yong | 2015 | Journal of Money Economics2015，，： | 1 |
| 17 | Collectivization and China's Agricultural Crisis in 1959 - 1961 显示文摘 | JUSTIN Yifu Lin | 1990 | The Journal of Political Econo- my1990，98，6： | 1 |
| 18 | Rural reforms and agricultural growth in China 显示文摘 | LIN YIFU | 1992 | The American Economic Review1992，82，1： | 1 |
| 19 | Institution Reform and Dynamics of Agricultural Growth in China显示文摘 | Justin Yifu Lin | 1997 | Food policy1997，22，3： | 1 |
| 20 | Rural reforms and agricultural growth in China显示文摘 | JUSTIN YIFU LIN | 1992 | the Arnerican Economic Review1992，82，1： | 1 |
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