|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of Zuogui pill and Yougui pill on osteoporosis: a randomized controlled trial显示文摘OBJECTIVE: To evaluate the effect and safety of Zuogui pill and Yougui pill, classic Yin and Yang tonic formula(CYYTF), in the treatment of osteoporosis and the underlying mechanism.METHODS: Participants aged 55 to 75 with osteoporosis and Kidney deficiency in Traditional Chi-nese Medicine(TCM) will be included and randomly allocated into two groups: treatment group and control group. Participants in the treatment group were treated with Zuogui pill or Yougui pill TCM formula granule, while the control group received placebo. Primary outcomes are the lumbar spine on bone mineral density(BMD)(L1-4) and femoral BMD. Secondary outcomes include pain intensity,health-related quality of life(HRQo L), bone turnover markers and safety.RESULTS: Totally 200 patients were enrolled from December 2014 to April 2016 from four hospitals.There were no statistically significant differences between the two groups at baseline(P > 0.05) and it was good to comparability. Statistically significant differences between the two groups were observed for the lumbar BMD(L1-4), pain VAS scores and HRQo L at six months and twelve months and femoral BMD at twelve months(P < 0.05), but no significant differences for femoral BMD and bone turnover markers at six months(P > 0.05). Moreover, significant difference was observed at different time before and after treatment in terms of lumbar spine(L1-4) BMD, femoral BMD, pain VAS scores and health-related quality of life, and there was an crossover effect between the time and groups before and after treatment. In additional, in the treatment group, 8 patients lost to follow-up and 3 patients had adverse events(AEs) and in the control group, 10 patients lost to follow-up and 2 patients had AEs. No remarkable differences were observed between the two groups with regard to AEs, lost rate and safety(P > 0.05).CONCLUSION: Zuogui pill or Yougui pill could improve BMD, ease pain, relieve Kidney deficiencysyndrome, improve the quality of life osteoporosis patients, inhibit bone conversion and regulate the coupling balance of bone formation and bone resorption, but long-term efficacy should be confirmed by a longer term follow-up and larger of samples clinical randomized controlled trials. | Li Wenxiong Zhang Kuaiqiang Liu Zhu Liu Li Cheng Yan Yin Jichao Sun Yindi Yang Feng | 2018 | Journal of Traditional Chinese Medicine2018，38，1： | 3 |
| 2 | Therapeutic Effect Analysis of Sodium Aescinate Tablets on Knee Osteoarthritis Combined with Synovitis显示文摘Objective:To observe therapeutic effect of sodium aescinate Tablets on knee osteoarthritis complicated with synovitis.Methods:86 patients with knee osteoarthritis combined with synovitis treated in the Honghui Hospital Affiliated to Xi’an Jiaotong University from January 2018 to December 2019 were randomly divided into control group and intervention group,with 43 cases in each group.The control group was given routine treatment,and the intervention group was given sodium aescinate Tablets orally on the basis of routine treatment,twice a day,2 tablets each time.The curative effect was evaluated after 2 weeks of treatment.The knee pain and joint function of the two groups were evaluated by Visual Analogue Scale(VAS)and Western Ontario and McMaster Universities Arthritis Index(WOMAC),and the clinical effects of the two groups were compared.Results:Before treatment,there was no significant difference in general information,VAS and WOMAC scores between the two groups(P>0.05).After treatment,the VAS and WOMAC scores of the two groups were both lower than those before treatment,and the difference was statistically significant(P<0.05).The vas and WOMAC scores of the intervention group were lower than those of the control group(VAS,1.87±0.79 vs 3.38±0.81).In this study,sodium aescinate tablets were applied to the treatment of KOA combined with synovitis.The results showed that the intervention group was better than the control group in alleviating knee pain,improving joint function and improving clinical efficacy,and the difference was statistically significant.The total effective rate of the intervention group was higher than that of the control group(100%vs 86.05%),and the difference was statistically significant(P<0.05).Conclusion:Sodium aescinate tablet in the treatment of knee osteoarthritis combined with synovitis can effectively alleviate knee pain,improve joint function and improve clinical efficacy. | Xueqin Zeng Baohui Wang Liang Li Tao Lei Huajian Liu Yindi Sun | 2021 | Journal of Clinical and Nursing Research2021，5，6： | 0 |
| 3 | Advance in Nutritional Status and Intervention after Spinal Cord Injury显示文摘Spinal cord injury(SCI)is a common disease in spinal surgery.SCI affects the metabolism of patients and changes their lifestyle.Nutritional problems may occur,which may be manifested as insufficient or overnutrition.Nutrition status is related to many complications and final outcome after SCI.In this paper,the nutritional status of patients with SCI and the progress of nutritional intervention were reviewed by comprehensive domestic and foreign literature.Medical staff should routinely screen and evaluate the nutrition of patients after SCI operation,and provide comprehensive nutritional intervention such as diet,exercise and dietary supplement. | Xueqin Zeng Jie Xiang Lu Dong Bo Dong Yindi Sun | 2021 | Journal of Clinical and Nursing Research2021，5，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员