5篇
您的检索式：作者名="Yingfeng Shao"
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| 1 | A novel method for preparation of hollow and solid carbon spheres显示文摘 | Boyang Liu Dechang Jia Jiancun Rao Qiangchang Meng Yingfeng Shao | 2008 | Bulletin of Materials Science2008，，5： | 1 |
| 2 | A sensitivity-based approach for pruning architecture of Madalines显示文摘 | Xiaoqin Zeng Jing Shao Yingfeng Wang Shuiming Zhong | 2009 | Neural Computing and Applications2009，，8： | 1 |
| 3 | A sensitivity-based approach for pruning architecture of Madalines显示文摘 | Xiaoqin Zeng Jing Shao Yingfeng Wang Shuiming Zhong | 2009 | Neural Computing and Applications2009，，8： | 1 |
| 4 | Bladder microenvironment actuated proteomotors with ammonia amplification for enhanced cancer treatment显示文摘Enzyme-driven micro/nanomotors consuming in situ chemical fuels have attracted lots of attention for biomedical applications.However,motor systems composed by organism-derived organics that maximize the therapeutic efficacy of enzymatic products remain challenging.Herein,swimming proteomotors based on biocompatible urease and human serum albumin are constructed for enhanced antitumor therapy via active motion and ammonia amplification.By decomposing urea into carbon dioxide and ammonia,the designed proteomotors are endowed with self-propulsive capability,which leads to improved internalization and enhanced penetration in vitro.As a glutamine synthetase inhibitor,the loaded L-methionine sulfoximine further prevents the conversion of toxic ammonia into non-toxic glutamine in both tumor and stromal cells,resulting in local ammonia amplification.After intravesical instillation,the proteomotors achieve longer bladder retention and thus significantly inhibit the growth of orthotopic bladder tumor in vivo without adverse effects.We envision that the as-developed swimming proteomotors with amplification of the product toxicity may be a potential platform for active cancer treatment. | Hao Tian Juanfeng Ou Yong Wang Jia Sun Junbin Gao Yicheng Ye Ruotian Zhang Bin Chen Fei Wang Weichang Huang Huaan Li Lu Liu Chuxiao Shao Zhili Xu Fei Peng Yingfeng Tu | 2023 | Acta Pharmaceutica Sinica B2023，13，9： | 0 |
| 5 | Entropic pressure between fluctuating membranes in multilayer systems显示文摘Gaining insights into the fluctuation-induced entropic pressure between membranes that mediates cell adhesion and signal transduction is of great significance for understanding numerous physiological processes driven by intercellular communication.Although much effort has been directed toward investigating this entropic pressure,there still exists tremendous controversy regarding its quantitative nature,which is of primary interest in biophysics,since Freund challenged the Helfrich’s well-accepted results on the distance dependence.In this paper,we have investigated the entropic pressure between fluctuating membranes in multilayer systems under pressure and tension through theoretical analysis and Monte Carlo simulations.We find that the scaling relations associated with entropic pressure depend strongly on the magnitude of the external pressures in both bending rigidityand surface tension-dominated regimes.In particular,both theoretical and computational results consistently demonstrate that,in agreement with Helfrich,the entropic pressure p decays with inter-membrane separations c as p^c^(–3)for the tensionless multilayer systems confined by small external pressures.However,our results suggest that the entropic pressure law follows to be p^c^(–1)and p^c^(–3),respectively,in the limit of large and small thermal wavelengths for bending fluctuations of the membranes in a tensionindependent manner for the case of large external pressures. | Long Li Xiaohuan Wang Yingfeng Shao Wei Li Fan Song | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，12： | 0 |
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