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| 1 | Precision in Liver Surgery显示文摘 | Jiahong Dong ShiZhong Yang Jianping Zeng Shouwang Cai Wenbin Ji Weidong Duan Aiqun Zhang Weizheng Ren Yinzhe Xu Jingwang Tan Xiangyang Bu Ning Zhang Xuedong Wang Xianqiang Wang Xiangfei Meng Kai Jiang Wanqing Gu Zhiqiang Huang | 2013 | Semin Liver Dis2013,,03: | 2 |
| 2 | GOLM1 restricts colitis and colon tumorigenesis by ensuring Notch signaling equilibrium in intestinal homeostasis显示文摘Intestinal epithelium serves as the first barrier against the infections and injuries that mediate colonic inflammation.Colorectal cancer is often accompanied with chronic inflammation.Differed from its well-known oncogenic role in many malignancies,we present here that Golgi membrane protein 1(G0LM1,also referred to as GP73)suppresses colorectal tumorigenesis via maintenance of intestinal epithelial barrier.G0LM1 deficiency in mice conferred susceptibility to mucosal inflammation and colitis-induced epithelial damage,which consequently promoted colon cancer.Mechanistically,depletion of G0LM1 in intestinal epithelial cells(lECs)led to aberrant Notch activation that interfered with IEC differentiation,maturation,and lineage commitment in mice.Pharmacological inhibition of Notch pathway alleviated epithelial lesions and restrained pro-tumorigenic inflammation in G0LM1-deficient mice.Therefore,G0LM1 maintains IEC homeostasis and protects against colitis and colon tumorigenesis by modulating the equilibrium of Notch signaling pathway. | Yang Pu Ya Song Mengdi Zhang Caifeng Long Jie Li Yanan Wang Yinzhe Xu Fei Pan Na Zhao Xinyu Zhang Yanan Xu Jianxin Cui Hongying Wang Yan Li Yong Zhao Di Jin Hongbing Zhang | 2021 | Signal Transduction and Targeted Therapy2021,6,5: | 2 |
| 3 | Recovery of catechin compounds from Korean tea by solvent extraction 显示文摘 | Kyung H R Yinzhe J | 2006 | Bioresource Technology2006,97,5: | 1 |
| 4 | Fast local rerouting for handling transient link failures显示文摘 | Srihari Nelakuditi Sanghwan Lee Yinzhe Yu Zhi-Li Zhang Chen-Nee Chuah | 2007 | IEEE/ACM Transactions on Networking (TON)2007,,2: | 1 |
| 5 | Jujube preservation using chitosan film with nano-silicon dioxide显示文摘 | Youwei Yu Shaoying Zhang Yinzhe Ren Hui Li Xiaona Zhang Jinhua Di | 2012 | Journal of Food Engineering2012,,3: | 1 |
| 6 | Precision of future experiments measuring primordial tensor fluctuation显示文摘Recently the second phase of Background Imaging of Cosmic Extragalactic Polarization(BICEP2)claimed a detection of the tensor-to-scalar ratio(r)of primordial fluctuation at 5σconfidence level.If it is true,this large and measurable amplitude(r0.2)of B-mode polarization indicates that it is possible to measure the shape of CMB B-mode polarization with future experiments.Given the current understanding of the experimental noise and foreground contamination,we forecast the precision of r and the tensor spectral index ntmeasurements from Planck,Spider and POLARBEAR with ntas a free parameter.We quantitatively determine the signal-to-noise of the measurement in r-ntparameter space for the three experiments.The forecasted signal-to-noise ratio of the B-mode polarization somewhat depends on nt,but strongly depends on the true value of r. | WANG Yi MA YinZhe | 2014 | Science China(Physics,Mechanics & Astronomy)2014,57,8: | 1 |
| 7 | Jujube preservation using chitosan film with nano-silicon dioxide显示文摘 | YU Youwei ZHANG Shaoying REN Yinzhe | 2012 | Journal of Food Engineering2012,113,: | 1 |
| 8 | Jujube preservation using chitosan film with nano-silicon dioxide 显示文摘 | Youwei Yu Shaoying Zhang Yinzhe Ren | 2012 | Journal of Food Engineering2012,113,3: | 1 |
| 9 | A facile approach to construct three-dimensional oriented chitosan scaffold显示文摘 | Yinzhe Li Youxiang Dao Wu KAI ZHEANG Qiaoling Hu | | 0,,: | 1 |
| 10 | Bioorthogonal microglia-inspired mesenchymal stem cell bioengineering system creates livable niches for enhancing ischemic stroke recovery via the hormesis显示文摘Mesenchymal stem cells(MSCs)experience substantial viability issues in the stroke infarct region,limiting their therapeutic efficacy and clinical translation.High levels of deadly reactive oxygen radicals(ROS)and proinflammatory cytokines(PC)in the infarct milieu kill transplanted MSCs,whereas low levels of beneficial ROS and PC stimulate and improve engrafted MSCs’viability.Based on the intrinsic hormesis effects in cellular biology,we built a microglia-inspired MSC bioengineering system to transform detrimental high-level ROS and PC into vitality enhancers for strengthening MSC therapy.This system is achieved by bioorthogonally arming metabolic glycoengineered MSCs with microglial membrane-coated nanoparticles and an antioxidative extracellular protective layer.In this system,extracellular ROSscavenging and PC-absorbing layers effectively buffer the deleterious effects and establish a microlivable niche at the level of a single MSC for transplantation.Meanwhile,the infarct’s inanimate milieu is transformed at the tissue level into a new living niche to facilitate healing.The engineered MSCs achieved viability five times higher than natural MSCs at seven days after transplantation and exhibited a superior therapeutic effect for stroke recovery up to 28 days.This vitality-augmented system demonstrates the potential to accelerate the clinical translation of MSC treatment and boost stroke recovery. | Jianpei Xu Yinzhe Sun Yang You Yuwen Zhang Dan Huang Songlei Zhou Yipu Liu Shiqiang Tong Fenfen Ma Qingxiang Song Chengxiang Dai Suke Li Jigang Lei Zhihua Wang Xiaoling Gao Jun Chen | 2024 | Acta Pharmaceutica Sinica B2024,14,3: | 0 |