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| 1 | Defects and interface states related photocatalytic properties in reduced and subsequently nitridized Fe_3O_4/TiO_2显示文摘The Fe_3O_4@TiO_2 catalyst was reduced in a mixed H_2/N_2 atmosphere at temperatures of 400, 600, 800 and 1000?C in order to produce the oxygen vacancies(O_v) and Ti^(3+); Simultaneously, Fe_3O_4 was reduced to Fe, a strongly magnetic material, beneficial for the magnetic separation after the photo-degradation.The optimal catalyst was obtained at the reducing temperature of 800?C, which possesses the good photocatalytic performance and recycled activities; Moreover, its saturation magnetization Msis highest,reaching 23.8 emu g^(-1) which improves the magnetic separability. This optimal catalyst was subsequently treated in the NH_3 atmosphere at temperatures of 500, 600 and 700?C, aiming to investigate the effects of N-doping in TiO_2. The 600?C treated catalyst exhibited the optimal photocatalytic performance. The factors that affect the photocatalytic performance are revealed and discussed in detail, including the ratio of Ovand N dopant in TiO_2 as well as the interface states between TiO_2 and the magnetic particles. | Chang Liu Xiang Zhu Peng Wang Yisen Zhao Yongqing Ma | 2018 | Journal of Materials Science & Technology2018，34，6： | 3 |
| 2 | Statin treatment for unruptured intracranial aneurysms study: a study protocol for a double-blind, placebocontrolled trial显示文摘background and purpose A large proportion of patients with unruptured intracranial aneurysm(IA)are not suitable for surgical clipping and endovascular treatment.For these patients,anti-inflammatory medications are worth exploring due to inflammation of aneurysmal wall being a major factor in higher risk of rupture.Statin has been proven to reduce inflammation of atherosclerosis and maybe a suitable candidate.This study aimed to evaluate whether atorvastatin will reduce inflammatory of the aneurysm wall measured by the signal index of aneurysm wall enhancement.Methods and analysis The Statin Treatment for UnruptureD Intracranial anEurysms Study is a single-centre,phase 2,randomised,controlled,double-blind clinical trial.60 patients with unruptured IAs with aneurysm wall enhancement will be enrolled in Beijing Tiantan Hospital.The patients will be randomised to receive atorvastatin 20 mg or placebo orally per day for 12 months.The primary outcome will be the change in aneurysm wall enhancement measured by the signal index during the 12 months treatment with atorvastatin.The secondary study outcomes will be the change in aneurysm wall enhancement measured by the signal index at 3 months,the changes in aneurysmal morphology and inflammation-related factors(C reactive protein,tumour necrosis factor-α,interleukin-1βand interleukin-6)at 3 and 12 months.This study is the first to explore the role of atorvastatin in reducing inflammation in unruptured IA,which could lay the groundwork for future phase III trial.Ethics and dissemination Beijing Tiantan Hospital’s Ethics committee approved the research and written informed consents would be obtained from all participant or representative included in this study. | Wenqiang Li Yisen Zhang Zhongbin Tian Wei Zhu Jian Liu Ying Zhang Xinjian Yang De-Cai Tian | 2020 | Stroke & Vascular Neurology2020，5，4： | 2 |
| 3 | Endovascular treatment of bilateral intracranial vertebral artery aneurysms: an algorithm based on a 10- year neurointerventional experience显示文摘Background The management of bilateral intracranial vertebral artery dissecting aneurysms(IVADAs)is controversial,and requires the development of endovascular treatment modalities and principles.We aim to investigate the endovascular treatment strategy and outcomes of bilateral IVADAs.Methods We identified all bilateral IVADAs at a high-volume neurointerventional centre over a 10-year period(from January 2009 to December 2018).Radiographic and clinical data were recorded,and a treatment algorithm was derived.Results Twenty-seven patients with bilateral IVADAs(54 IVADAs in total,51 unruptured,3 ruptured)were diagnosed.Four patients(14.8%)received single-stage endovascular treatment,12 patients(44.4%)with staged endovascular treatment and 11 patients(40.8%)with unilateral endovascular treatment of bilateral IVADAs.Thirty-six IVADAs(85.7%)have complete obliteration at the follow-up angiography.Two of three ruptured IVADAs with stent-assisted coiling recanalised,and had further recoiling.Three patients(11.1%)have intraprocedural or postprocedural complications(two in single-stage and one in staged).Twenty-five patients(92.6%)had a favourable clinical outcome,and two patients(7.4%,all in single-stage)showed an unfavourable clinical outcome at follow-up.For the patients with unilateral reconstructive endovascular treatment,the contralateral untreated IVADAs were stable and had no growth or ruptured during follow-up period.None of all IVADAs had rebleeding during the clinical follow-up.Conclusions Endovascular treatment can be performed in bilateral IVADAs with high technical success,high complete obliteration rates and acceptable morbidity/mortality.Contralateral IVADAs had low rates of aneurysm growth and haemorrhage when treated in a staged/delayed fashion. | Yisen Zhang Zhongbin Tian Wei Zhu Jian Liu Yang Wang Kun Wang Ying Zhang Xinjian Yang Wenqiang Li | 2020 | Stroke & Vascular Neurology2020，5，3： | 2 |
| 4 | Significant flow velocity reduction at the intracranial aneurysm neck after endovascular treatment leads to favourable angiographic outcome:a prospective study显示文摘Background With widely usage of flow diverter in intracranial aneurysm treatment,some previously used predictors may not be effective in evaluating the recurrence risk.We aimed to comprehensively re-evaluate the predictors of intracranial aneurysm outcome with various endovascular treatment methods and devices.Methods This is a prospective registered study.We analysed 6-month and 18-month follow-up angiographic data from the prospective study.Data on patient demographics,aneurysm morphology and type of treatment were recorded.Patient-specific haemodynamic simulations were performed.An unfavourable angiographic outcome was defined as recurrence of aneurysm in cases with coiling or stent-assisted coiling,patency of aneurysm in cases with flow diverters or retreatment during follow-up.Results In total,165 patients(177 intracranial aneurysms)with at least one angiographic follow-up data were analysed.For the short-term(6-month)results,after univariate analysis,the demographic,morphological and treatment-related factors did not achieve significantly statistical differences.The reduction ratio(RR)of velocity at aneurysm neck after embolisation was significantly lower in the unfavourable angiographic group than the favourable angiographic outcome group(p=0.002).After the Cox regression analysis,the RR of velocity at aneurysm neck was the only independent factor associated with favourable angiographic outcome(OR 0.028;p=0.001)and had an acceptable area under the curve(0.714)with a clear cut-off value(46.14%).Similarly,for the analysis of midterm(18-month)results,the RR of velocity at the aneurysm neck was the only independent significant factor for the unfavourable angiographic outcome(OR 0.050;p=0.017).The area under the curve was 0.754 and the cut-off value was 48.20%.Conclusions The haemodynamics showed an independent effect on angiographic follow-up results and may provide helpful suggestions for clinical practice in the future. | Zhongbin Tian Jian Liu Jay Kumar Wenqiang Li Yisen Zhang Ying Zhang Kun Wang Shengzhang Wang Zeguang Ren Xinjian Yang | 2021 | Stroke & Vascular Neurology2021，6，3： | 1 |
| 5 | Numerical study of soil collapse behavior by discrete element modelling显示文摘 | S.H. Liu D.A. Sun Yisen Wang | 2003 | Computers and Geotechnics2003，，5： | 1 |
| 6 | Treatment for Expansive Soil Channel Slope with Soilbags显示文摘 | Sihong Liu Fuqing Bai Yisen Wang Shan Wang Zhuo Li | 2013 | Journal of Aerospace Engineering2013，，： | 1 |
| 7 | Seasonal linkage of the Southern Hemisphere extratropical climate variability to two types of ENSO显示文摘This study uses the Climate Forecast System Reanalysis(CFSR) to investigate the responses of the Southern Hemisphere(SH) extratropical climate to two types of El Nino–Southern Oscillation(ENSO)-the eastern Pacific(EP) type and the central Pacific(CP) type in different seasons. The responses are denoted by the anomalies of climate variables associated with one-standard-deviation increase in the Nino3 or Nino4 index. The results show that in austral spring the differences in the ENSO-related anomaly(ERA) patterns of atmospheric circulation between the EP ENSO period(1979–1998) and CP ENSO period(1999–2010) are mainly associated with the change in the ENSO-PSA2 relationship. Such differences affect the ERA fields of surface air temperature and mixed layer temperature, and finally result in significant differences in sea-ice concentration anomalies in the Atlantic sector. In austral summer, significant correlation exists between the variations of SAM and both of the variations of Nino3 and Nino4 in 1979–1998, while the correlation between SAM and Nino4 disappears in 1999–2010. For all seasons, the strength of the climate ERAs depend on if there are close relationship between ENSO and the major climate variation modes of the SH extratropics. For the climate variables, the ERA patterns of surface air temperature are generally controlled by surface wind anomalies and mirrored by the mixed layer temperature anomalies. The mixed layer depth anomalies are primarily modulated by surface heat flux anomalies and occasionally by anomalous wind. There are strikingly strong anomalies of surface heat flux in the autumn of 1979–1998 related to the Nino3 variation, the period when there is only significant correlation between ENSO and PSA2. There are no evidence that the SH extratropical climate variability induced by Nino3 variations are stronger in the EP-ENSO period, and that variability induced by Nino4 variations are stronger in the CP-ENSO period. | Zhongpeng Wang Zhaoru Zhang Meng Zhou Hailong Liu Yisen Zhong Xiaoqiao Wang | 2020 | Acta Oceanologica Sinica2020，39，1： | 1 |
| 8 | Industrialization progress and challenges of cultivated meat显示文摘With its more sustainable production mode and higher healthy food supplying,cultivated meat is gradually regarded as the promising alternative meat food in future by human beings.Most of the countries in the planet had participated in the cut-throat competition for sustainable protein searching,especially for the regions with low food self-sufficiency rate.In this paper,by reviewing the commercial market participation,product development stage,and technical research progress related to cultivated meat in detail,we demonstrated the industrialization progress of cultivated meat and explored the challenges of cultivated meat in the near future.1)Seeded cell and serum free medium were the basic raw materials,which were directly related to the food safety regulation,production cost control and productivity improvement;2)Bioreactor and regulation were the cornerstone of industrialization,which were closely related to the capacity expansion,product marketing;3)Technological improvements in taste,texture,safety,scale,cost were the foundation of realizing product iterative upgrade and market acceptance. | Jiaqi Cai Shouwei Wang Yingying Li Shengyan Dong Jun Liang Yisen Liu Shilei Li | 2024 | Journal of Future Foods2024，4，2： | 1 |
| 9 | Treatment for expansive soil channel slope with soilbags显示文摘 | LIU SIHONG BAI FUQINC WANG YISEN | 2013 | Journal of Aerospace Engineering2013，26，4： | 1 |
| 10 | Hemodynamic analysis for endovascular treatment in small unruptured intracranial aneurysms:a matched comparison study of flow diverter versus LVIS显示文摘Background:We compared the treatment of small unruptured intracranial aneurysms(UIAs)with flow diverter and LVIS-assisted coiling to determine the effects of hemodynamic changes caused by different stent and coil packing in endovascular treatment.Methods:Fifty-one UIAs in 51 patients treated with pipeline embolization device(PED)were included in this study and defined as the PED group.We matched controls 1:1 and enrolled 51 UIAs who were treated with LVIS stent,which were defined as the LVIS group.Computational fluid dynamics were performed to assess hemodynamic alterations between PED and LVIS.Clinical analysis was also performed between these two groups after the match.Results:There was no difference in procedural complications between the two groups(P=0.558).At the first angiographic follow-up,the complete occlusion rate was significantly higher in the LVIS group compared with that in the PED group(98.0%vs.82.4%,P=0.027).However,during the further angiographic follow-up,the complete occlusion rate in the PED group achieved 100%,which was higher than that in the LVIS group(98.0%).Compared with the LVIS group after treatment,cases in the PED group showed a higher value of velocity in the aneurysm(0.03±0.09 vs.0.01±0.01,P=0.037)and WSS on the aneurysm(2.32±5.40 vs.0.33±0.47,P=0.011).Consequently,the reduction ratios of these two parameters also showed statistical differences.These parameters in the LVIS group showed much higher reduction ratios.However,the reduction ratio of the velocity on the neck plane was comparable between two groups.Conclusions:Both LVIS and PED were safe and effective for the treatment of small UIAs.However,LVIS-assisted coiling produced greater hemodynamic alterations in the aneurysm sac compared with PED.The hemodynamics in the aneurysm neck may be a key factor for aneurysm outcome. | Jian Liu Wenqiang Li Yisen Zhang Kun Wang Xinjian Yang Ying Zhang | 2022 | Chinese Neurosurgical Journal2022，8，2： | 0 |
| 11 | Mutational spectrum of syndromic genes in sporadic brain arteriovenous malformation显示文摘Background:Brain arteriovenous malformations(BAVMs)are abnormal vessels that are apt to rupture,causing lifethreatening intracranial hemorrhage(ICH).The estimated prevalence of BAVMs is 0.05%among otherwise healthy individuals.In this study,we aim to investigate the mutational spectrum of syndromic genes in sporadic BAVM.Methods:We recruited a cohort of 150 patients with BAVM and performed whole-exome sequencing on their peripheral blood DNA.To explore the mutational spectrum of syndromic genes in sporadic brain arteriovenous malformation,we selected six genes according to the Online Mendelian Inheritance in Man(OMIM)and literature.All variants in the six candidate genes were extracted and underwent filtering for qualifying variants.Results:There are a total of four patients with rare variants in hereditary hemorrhagic telangiectasia-related genes.In addition,we identified two patients have the variant of RASA1 gene in our database,which are also rare mutations that are absent from population databases.However,we did not find any patients with GNAQ mutations in our database.Conclusions:In conclusion,we demonstrated that variants in syndromic vascular malformations play important roles in the etiology of sporadic BAVM. | Kun Wang Mingqi Zhang Sen Zhao Zhixin Xie Yisen Zhang Jian Liu Ying Zhang Xinjian Yang Nan Wu | 2022 | Chinese Neurosurgical Journal2022，8，2： | 0 |
| 12 | Ultrafast growth of wafer-scale fold-free bilayer graphene显示文摘Bilayer graphene provides a versatile platform for exploring a variety of intriguing phenomena and shows much promise for applications in electronics,optoelectronics,etc.Controlled growth of large-area bilayer graphene is therefore highly desired yet still suffers from a slow growth rate and poor layer uniformity.Meanwhile,graphene wrinkles,including folds and ripples,form during cooling due to the thermal contraction mismatch between graphene and the metal substrates,and have been far from suppressed or eliminated,especially in bilayer graphene,which would greatly degrade the extraordinary properties of graphene.Here we report the ultrafast growth of wafer-scale fold-free bilayer graphene by chemical vapor deposition.Through well-tuning the alloy thickness and strain regulation of the single-crystal CuNi(111)/sapphire,the full coverage of a 2-inch fold-free bilayer graphene wafer via mainly isothermal segregation has been achieved as fast as 30 s.The tensile-strained CuNi(111)film reduces the thermal contraction mismatch and suppresses the formation of graphene folds during cooling,which is directly observed through in situ optical microscopy.The ultraflat bilayer graphene exhibits wafer-scale uniformity in electrical performance and enhanced mechanical property comparable to the exfoliated ones.Our results offer a promising route for largescale production of bilayer graphene and enable its various applications. | Jilin Tang Yuechen Wang Yuwei Ma Xiaoyin Gao Xin Gao Ning Li Yani Wang Shishu Zhang Liming Zheng Bing Deng Rui Yan Yisen Cao Ronghua Zhang Lianming Tong Jin Zhang Peng Gao Zhongfan Liu Xiaoding Wei Hongtao Liu Hailin Peng | 2023 | Nano Research2023，16，7： | 0 |
| 13 | Statistical characteristics of mesoscale eddies on the continental slope in the northern South China Sea显示文摘The continental slope in the northern South China Sea(SCS) is rich in mesoscale eddies which play an important role in transport and retention of nutrients and biota. In this study, we investigate the statistical properties of eddy distributions and propagation in a period of 24 years between 1993 and 2016 by using the altimeter data. A total of 147 eddies are found in the continental slope region(CSR), including 70 cyclonic eddies(CEs) and 77 anticyclonic eddies(ACEs). For those eddies that appear in the CSR, the surrounding areas of Dongsha Islands(DS) and southwest of Taiwan(SWT) are considered as the primary sources, where eddies generated contribute more than 60% of the total. According to the spatial distribution of eddy relative vorticity, eddies are weakening as propagating westward. Although both CEs and ACEs roughly propagate along the slope isobaths, there are discrepancies between CEs and ACEs. The ACEs move slightly faster in the zonal direction, while the CEs tend to cross the isobaths with large bottom depth change. The ACEs generally move further into the basin areas after leaving the CSR while CEs remain around the CSR. The eddy propagation on the continental slope is likely to be associated with mean flow at a certain degree because the eddy trajectories have notable seasonal signals that are consistent with the seasonal cycle of geostrophic current. The results indicate that the eddy translation speed is statistically consistent with geostrophic velocity in both magnitude and direction. | Zi Cheng Meng Zhou Yisen Zhong Zhaoru Zhang Hailong Liu Lei Zhou | 2020 | Acta Oceanologica Sinica2020，39，3： | 0 |
| 14 | Risk factors for periprocedural ischemic stroke following endovascular treatment of intracranial aneurysms显示文摘Background:The aim of this study was to comprehensively evaluate the risk factors of periprocedural ischemic stroke associated with endovascular treatment of intracranial aneurysms using a real-world database.Methods:From August 2016 to March 2017,167 patients were enrolled.Univariate analysis and multivariate logistic regression analysis were used to examine the risk factors for periprocedural ischemic stroke.Results:Among the 167 cases,periprocedural ischemic stroke occurred in 20 cases(11.98%).After univariate analysis,the ischemic group had a higher proportion of large(≥10 mm)aneurysms than the control group(45.0%vs.23.1%,p=0.036).The incidence of periprocedural ischemic stroke was higher in cases treated by flow diverter(21.6%)or stent-assisted coiling(11.8%)than in cases treated by coiling only(2.7%),and the differences were statistically significant(p=0.043).After multivariate logistic regression analysis,treatment modality was the independent risk factor for periprocedural ischemic stroke.Compared with the coiling-only procedure,flow diverter therapy was associated with a significantly higher rate of periprocedural ischemic stroke(OR 9.931;95%CI 1.174-84.038;p=0.035).Conclusions:Aneurysm size and treatment modality were associated with periprocedural ischemic stroke.Larger aneurysms were associated with increased risk of periprocedural ischemic stroke.Flow diverter therapy was associated with significantly more periprocedural ischemic stroke than the coiling procedure alone. | Yisen Zhang Chao Wang Zhongbin Tian Wei Zhu Wenqiang Li Xinjian Yang Jian Liu Ying Zhang | 2022 | Chinese Neurosurgical Journal2022，8，1： | 0 |
| 15 | Mesoporous Cu_(3−x)Zn_(x)(BTC)_(2)nanocubes synthesized in deep eutectic solvent and their catalytic performances显示文摘To develop high-performance metal-organic frameworks(MOFs)for catalysis is of great importance.Here,we synthesized the mesoporous Cu_(3−x)Zn_(x)(BTC)_(2)(BTC=benzene-1,3,5-tricarboxylate)nanocubes in a deep eutectic solvent of ZnCl_(2)/ethylene glycol solution.The route can proceed at room temperature and the reaction time needed is shortened to be 30 min,which is superior to the conventional solvothermal route that usually needs high temperature and long reaction time.The formation mechanism of the mesoporous Cu_(3−x)Zn_(x)(BTC)_(2)nanocubes in deep eutectic solvent(DES)was investigated by in situ synchrotron X-ray diffraction/small angle X-ray scattering/X-ray absorption fine structure conjunction technique.The mesoporous Cu_(3−x)Zn_(x)(BTC)_(2)nanocubes exhibit high catalytic activity and reusability for cyanosilylation reaction of benzaldehyde and aerobic oxidation reaction of benzylic alcohol. | Jingyang Hu Jianling Zhang Xiuniang Tan Xiuyan Cheng Zhuizhui Su Lixiong Qian Mingzhao Xu Yufei Sha Yanyue Wang Yisen Yang Yunpeng Liu Guang Mo Xueqing Xing Zhonghua Wu | 2023 | Nano Research2023，16，3： | 0 |
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