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2篇 您的检索式：作者名="Yoshiki Seto"

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		题名	作者	年代	出处	被引量
	1	Development of self-micellizing solid dispersion system employing amphipathic copolymer for the improvement of dissolution and oral bioavailability of cyclosporine A显示文摘The main objective of the present study is to develop a selfmicellizing solid dispersion(SMSD)system of cyclosporine A(CsA)using an amphiphilic copolymer,poly[MPC-co-BMA](pMB)to improve the biopharmaceutical properties of CsA(Fig.1A).Unlike conventional carrier compounds,pMB would perform the bifunctional ability as both polymeric carrier of solid dispersion system and solubilizer derived from a high micellizing property,which could be considered beneficial for the production of highly water soluble formulation of poorly water soluble compound[1].Improvement in the aqueous solubility has been believed to be a key consideration for acquiring potent pharmacological effects of BCS class II drug like CsA.	Hiroki Suzuki Hideyuki Sato Yoshiki Kojo Takahiro Mizumoto Kayo Yuminoki Naohumi Hashimoto Yoshiki Seto Satomi Onoue	2016	Asian Journal of Pharmaceutical Sciences2016，11，1：	0
	2	Photosafety testing of dermally-applied chemicals based on photochemical and cassette-dosing pharmacokinetic data显示文摘Drug-induced phototoxicity is elicited by exposure of skin and/or eyes to topical or systemic administration of chemicals,followed by exposure to sunlight.For photosafety testing,a new screening strategy,employing in vitro photochemical/photobiological and in vivo cassette-dosing pharmacokinetic(PK)studies,was proposed[1,2].The screening system provided reliable phototoxic predictions of tested chemicals at least within the same chemical series;however,the applicability of the proposed strategy is not fully understood.	Hiroto Ohtake Yukiko Suzuki Masashi Kato Yoshiki Seto Satomi Onoue	2016	Asian Journal of Pharmaceutical Sciences2016，11，1：	0

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