2篇
您的检索式：作者名="Yu‑Shu Feng"
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| 1 | L‑Tyrosine Metabolic Pathway in Microorganisms and Its Application in the Biosynthesis of Plant‑Derived Natural Products显示文摘L-tyrosine,an aromatic amino acid,is an important upstream precursor for the synthesis of a series of valuable natural products such as flavonoids and phenolic acids.In recent years,regulation of the L‑tyrosine metabolic pathway has been devoted to enhancing the production of L-tyrosine and the derived bioactive compounds in microorganisms,usually by increasing the supply of precursors,blocking competitive routes,and modulating the transport system.Here,we reviewed the strategies to promote L-tyrosine production in microbial hosts and the common strategies to produce bioactive compounds in engineered Escherichia coli and Saccharomyces cerevisiae to better understand and utilize the L-tyrosine metabolic pathway for microbial overproduction of diverse valuable aromatic compounds in the future. | Yi‑Wen Zhang Feng Nie Xiao‑Yu Zheng Shu‑Juan Zhao | 2022 | World Journal of Traditional Chinese Medicine2022，8，3： | 0 |
| 2 | Tackling barriers to scale up human papillomavirus vaccination in China:progress and the way forward显示文摘The human papillomavirus(HPV)vaccine is the first vaccine developed specifically targeting the prevention of cervical cancer.For more than 15 years,China has expedited a series of efforts on research and development of the domestically manufactured HPV vaccines,producing local population-based evidence,promoting free HPV vaccination from pilots,and launching action plans to tackle barriers in the scale-up of HPV vaccination.To further roll out the HPV vaccination program in China,several challenges should be addressed to support the steps forward.The availability of more locally manufactured HPV vaccines,pricing negotiation and local evidence supporting the efficacy of one-dose schedule would greatly alleviate the continued supply and financial constraints in China.Meanwhile,more attention should be paid to girls living in low-resource areas and males to ensure equal access to the HPV vaccination.Furthermore,linkage to secondary prevention and further real-world monitoring and evaluation are warranted to inform effective cervical cancer prevention strategies in the post-vaccine era. | Xue‑Lian Zhao Shang‑Ying Hu Jia‑Wei Hu Hong‑Hao Wang Tian‑Meng Wen Yu‑Shu Feng You‑Lin Qiao Fang‑Hui Zhao Yong Zhang | 2023 | Infectious Diseases of Poverty2023，12，5： | 0 |
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