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| 1 | Dynamic and ultrastructural study of sphincter of Oddi in early-stage cholelithiasis in rabbits with hypercholesterolemia显示文摘AIM To study the relationship between pre-formation of gallstone and the kinetics and ultra-structure of sphincter of Oddi.METHODS Adult female rabbits were used anddivided into 3 groups,and fed with either normalor high cholesterol diet for four or eight weeks.Each group contained eight rabbits.Themanometry of sphincter of Oddi,biliarycineradiography,gallbladder volumemeasurement and ultrastructure observationunder electron microscope were performed.RESULTS In groups Ⅰ and Ⅱ,the basalpressure in low-pressure ampulla or highpressure zone of sphincter of Oddi waselevated,the amplitude of phasic contractionwas decreased and the volume of gallbladderwere increased,with a significant difference(P<0.01)from those of control.Gallstones werefound in group Ⅱ rabbits(7/8).Undercineradiography,low-pressure ampulla showeda spasmodic status without apparent peristalticcontraction.Under electron microscope,insidethe muscular cells of sphincter of Oddi,loosening of microfilament and swelling ofplasmosomes which congregated at the top wereobserved.The amount showed no obviouschange under nitric oxide synthase(NOS)stain.CONCLUSION Twisting of the microfilamentand disarrangement of kink macula densa insidethe muscular ceils suggested that the sphincterof Oddi was under spasmodic status.Theimpaired diastolic function caused andaggravated the stasis of cystic bile.Theswelling plasmosome could be one of theimportant factors in elevating the tonic pressureof sphincter of Oddi. | Wei JG Wang YC Du F Yu HJ | 2000 | World Journal of Gastroenterology2000，6，1： | 19 |
| 2 | Sedation and safety of propofol for therapeutic endoscopic retrograde cholangiopancreatography显示文摘Endoscopic retrograde cholangiopancrea tography(ERCP) is the most complex gastrointestinal procedure,which needs patients’ cooperation. The aim of this study was to observe the quality and safey of sedation with propofol in patients undergoing therapeutic ERCP. METHODS:Seventy patients who had undergone therapeutic ERCP were randomly divided into two groups.One group, given intravenously propofol, and the other sedated with routine method, served as the control. Blood pressure, heart rate,oxygen saturation were monitored and cardiorespiratory event was observed. Patient cooperation,performance, recovery time and amnesia served as variables postoperation. RESULTS:Blood pressure elevated in four patients in the propofol group, less than in the control group(P<0.01). Seven patients showed decreased blood pressure after administration of propofol,but none in the control group (P<0.01). Twelve patients in the control group showed mild or significant resistance, but none in the propofol group (P<0.01). The time for performance in the propofol group(P<0.05) was shorter than in the control group. Patient recovery was quicker in the propofol group than in the control group (P<0.01). The degree of amnesia better in the propofol group than in the control group ( P<0.01). The degree of amnesia was also better in the propofol group than in the control group (P<0.01). CONCLUSIONS:Propofol proves to be an excellent sedative for therapeutic ERCP. Being effective and safe, it shows a shorter ERCP duration but quick recovery and better amnesia. It is better than other routine sedatives. | Digestive Department (Chen WX, Lin HJ, Gu Q, Zhong XQ, Yu CH, Li YM and Gu ZY) and Department of Intensive Care Unit (Zhang WF), First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003 , China | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 10 |
| 3 | Application of carbazole compounds in study of hydrocarbon migration显示文摘IN recent years, studies on nitrogen compounds have been widely carried out by overseas schol-are, and achievements have been obtained spec1ally in the application of carbazoles to thestudy of hydrocarbon migration. But in China, few people work on this research area. | Liu, LF Xu, XD Mao, DF Yu, HJ | 1997 | Chinese Science Bulletin1997，42，23： | 6 |
| 4 | Inhibition of autophagy enhances cisplatin cytotoxicity through endoplasmic reticulum stress in human cervical cancer cells显示文摘 | Xu Yj Yu HM Qin HJ | 2012 | Cancer Lett2012，314，2： | 1 |
| 5 | In vitro and in vivo anti - inflam- matory activities of Polygonum hydropiper methanol extract 显示文摘 | Yang YY Yu T Jang HJ | 2012 | J Ethnopharmaco12012，39，2： | 1 |
| 6 | Role of MyD88 in TLR agonist-induced functional alterations of human adipose tissue-derived mesenchymal stem cells显示文摘 | Yu S Cho HH Joo HJ | 2008 | Mol Cell Biochem2008，317，12： | 1 |
| 7 | Prognostic significance of heat shock proteins in urothelial carcinoma of the urinary bladder显示文摘 | Yu HJ Chang YH Pan CC | 2013 | Histopathology2013，62，5： | 1 |
| 8 | Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus显示文摘 | Youn BS Yu KY Park HJ | 2004 | J Clin Endocrinol Metab2004，89，1： | 1 |
| 9 | Urachal remnant diseases: spectrum ofCT and US ndings显示文摘 | Yu JS Kim KW Lee HJ | 2001 | Radiographics2001，21，8： | 1 |
| 10 | hTERT promotes the in- vasion of telomerase-negative tumor cells in vitro显示文摘 | Yu ST Chen L Wang HJ | 2009 | Int J Oncol2009，35，2： | 1 |
| 11 | Analyzing fatal cases of Chinese patients with primary antineutrophil cytoplasmic antibodies-associated renal vasculitis:a 10-year retrospective study显示文摘 | Chen YX Yu HJ Zhang W | 2008 | Kidney Blood Press Res2008，31，5： | 1 |
| 12 | Site-saturated mutagenesis of histidine 234 of Saccha- romyces cerebisiae oxidosqualene-lanosterol cyclase demonstrates dual functions in cyclization and rear- rangement reactions显示文摘 | Wu TK Liu YT Chang CH Yu MT Wang HJ | 2006 | 128(19):6414-64192006，128，19： | 1 |
| 13 | Topicaladministration of peroxiredoxin-6 on the cornea suppresses in-flammation and neovascularization induced by ultraviolet radia-tion显示文摘 | Shi H Yu HJ Wang HY Wang WT Jin SH Zhu P | 2012 | /nuesf Ophthalmol Vis SW2012，53，13： | 1 |
| 14 | Comparison of the effects of human β-defensin 3,vancomycin,and clindamycin on Staphylococcus aureus biofilm formation显示文摘 | Huang Q Yu HJ Liu GD | | 0，，01： | 1 |
| 15 | Pharmacognostical studies on 'Ho-Jang' (III) 显示文摘 | Chi HJ Choi JR Yu SC | 1982 | Korean JPharmaeogn1982，13，： | 1 |
| 16 | Cervical disc prosthesis replacement and interbody fusion: a comparative study显示文摘 | Peng FS Yu HJ | 2008 | Int Orthop2008，1，： | 1 |
| 17 | Urachal remnant diseases:spectrum ofCT and US ngings显示文摘 | Yu JS Kim KW Lee HJ | 2001 | Radioraphics2001，21，9： | 1 |
| 18 | Clara cell 10-kDa protein inhibits T 《sub 》 H 《/sub 》 17 responses through modulating dendritic cells in the seuing of allergic rhinitis显示文摘 | Liu Y Yu HJ Wang N | | 0，，02： | 1 |
| 19 | A biodegradable triblock copolymer poly ( ethylene glycol )-b-poly ( L-lactide ) -b-poly ( L-lysine) : Synthesis, self-assembly, and RGD peptide modification 显示文摘 | Deng C Chen XS Yu HJ | 2007 | Polymer2007，411，1： | 1 |
| 20 | Relationship between soil erosion and distance to roadways in undeveloped areas of China显示文摘 | Shi XZ Wang K Warner ED Yu DS Wang HJ Yang RW Liang Y Shi DM | 2008 | Catena2008，72，： | 1 |
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