|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Cholecystokinin octapeptide antagonizes apoptosis in human retinal pigment epithelial cells显示文摘Although cholecystokinin octapeptide-8 is important for neurological function, its neuroprotective properties remain unclear. We speculated that cholecystokinin octapeptide-8 can protect human retinal pigment epithelial cells against oxidative injury. In this study, retinal pigment epithelial cells were treated with peroxynitrite to induce oxidative stress. Peroxynitrite triggered apoptosis in these cells, and increased the expression of Fas-associated death domain, Bax, caspase-8 and Bcl-2. These changes were suppressed by treatment with cholecystokinin octapeptide-8. These results suggest that cholecystokinin octapeptide-8 can protect human retinal pigment epithelial cells against apoptosis induced by peroxynitrite. | Yuan Liu Yueling Zhang Zhaohui Gu Lina Hao Juan Du Qian Yang Suping Li Liying Wang Shilei Gong | 2014 | Neural Regeneration Research2014，9，14： | 2 |
| 2 | Separation of bio-oil by molecular distillation显示文摘 | Shurong Wang Yueling Gu Qian Liu | 2009 | Fuel Process Technol2009，90，5： | 1 |
| 3 | UBE3A alleviates isoproterenol-induced cardiac hypertrophy through the inhibition of the TLR4/MMP-9 signaling pathway显示文摘Cardiac hypertrophy is considered to be a leading factor in heart function-related deaths.In this study,we explored the potential mechanism underlying cardiac hypertrophy induced by isoproterenol.Our results showed that isoproterenol induced cardiac hypertrophy in AC16 cells,as reflected by the increased cell surface area and increased hypertrophic markers,which was accompanied by increased ubiquitin-protein ligase E3a(UBE3A)expression.Moreover,UBE3A knockdown by siRNAs accelerated cardiac hypertrophy,suggesting that increased UBE3A expres sion induced by isoproterenol might be a protective response and UBE3A might be a protective factor against cardiac hypertrophy.Our study also revealed that UBE3A knockdown increased the protein expression of the TLR4/MMP-9 pathway that has been shown to be associated with cardiac hypertrophy,which suggested that UBE3A-mediated protection is likely to be associated with the blockade of the TLR4/MMP-9 signaling pathway.UBE3A might be thus a potential target gene for the treatment of cardiac hypertrophy. | Yanfei Li Linlin Ma Sijie Gu Jiewen Tian Yilin Cao Zi Jin Jingyi Chen Bingbing Gu Jiayin Tu Zhixiao Wang Xinming Li Zhongping Ning Yueling Jin | 2020 | Acta Biochimica et Biophysica Sinica2020，52，1： | 1 |
| 4 | Separation of bio-oil by molecular distillation显示文摘 | Wang Shurong Gu Yueling Liu Qian | 2009 | Fuel Processing Tech- nology2009，90，： | 1 |
| 5 | Separation ofbio-oil by molecular distillation显示文摘 | Wang Shurong Gu Yueling Liu Qian | 2009 | Fuel Processing Technology2009，90，： | 1 |
| 6 | Separation of bio-oil by molecular distillation显示文摘 | Shurong Wang Yueling Gu Qian Liu Yan Yao Zuogang Guo Zhongyang Luo Kefa Cen | 2009 | Fuel Processing Technology2009，，5： | 1 |
| 7 | Separation Characteristics of Biomass Pyrolysis Oil in Molecu- lar Distillation 显示文摘 | Zuogang Guo Shurong Wang Yueling Gu Guohui Xu Xin Li Zhongyang Luo | 2010 | Separation and Purification Technology2010，76，1： | 1 |
| 8 | Research on biomass fast pyrolysis for liquid fuel显示文摘 | Yueling Gu Kefa Cen | 2004 | Biomass & bioenergy2004，26，： | 1 |
| 9 | Separation characteristics of biomass pyrolysis oil in molecular distiUation显示文摘 | GUO Zuogang WANG Shurong GU Yueling | 2010 | Separation and Purification Technology2010，76，1： | 1 |
| 10 | Separation of bio-oil by molecular distillation显示文摘 | WANG Shurong GU Yueling LIU Qian | 2009 | Fuel Processing Technology2009，90，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员