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| 1 | Characterization of heavy-chain antibody gene repertoires in Bactrian camels显示文摘Camelids are the only mammals that can produce functional heavy-chain antibodies(HCAbs).Although HCAbs were discovered over 30 years ago,the antibody gene repertoire of Bactrian camels remains largely underexplored.To characterize the diversity of variable genes of HCAbs(VHHs),germline and rearranged VHH repertoires are constructed.Phylogenetics analysis shows that all camelid VHH genes are derived from a common ancestor and the nucleotide diversity of VHHs is similar across all camelid species.While species-specific hallmark sites are identified,the non-canonical cysteines specific to VHHs are distinct in Bactrian camels and dromedaries compared with alpacas.Though low divergence at the germline repertoire between wild and domestic Bactrian camels,higher expression of VHHs is observed in some wild Bactrian camels than that of domestic ones.This study not only adds our understanding of VHH repertoire diversity across camelids,but also provides useful resources for HCAb engineering. | Yuexing Liu Li Yi Yixue Li Zhen Wang Jirimutu | 2023 | Journal of Genetics and Genomics2023，50，1： | 2 |
| 2 | C1q/TNF-Related Proteins, A Family of Novel Adipokines, Induce Vascular Relaxation Through the Adiponectin Receptor-1/AMPK/eNOS/Nitric Oxide Signaling Pathway显示文摘 | Qijun Zheng Yuexing Yuan Wei Yi Wayne Bond Lau Yajing Wang Xiaoliang Wang Yang Sun Bernard L. Lopez Theodore A. Christopher Jonathan M. Peterson G. William Wong Shiqiang Yu Dinghua Yi Xin-Liang Ma | 2011 | Arteriosclerosis Thrombosis and Vascular Biology2011，，11： | 1 |
| 3 | Photoinduced Terminal Fluorine and Ti^(3+)in TiOF_(2)/TiO_(2)Heterostructure for Enhanced Charge Transfer显示文摘As an effective way to enhance the photo/electrocatalytic performance of titanium dioxide(TiO_(2))is to explore the positive roles of doped fluorine sites in the fluorinated TiO_(2)systems,which,currently still lacks the direct experimental evidence due to the complexity of the species involved.Herein,we have fabricated TiOF_(2)/TiO_(2)with interfacial bridging fluorine(Ti2-F)via a coherent phase transition through hydrothermal synthesis.Nuclear magnetic resonance and electron paramagnetic resonance characterization have provided strong evidence of the transformation of the doped fluorine from Ti2-F to Ti1-F and the subsequent generation of Ti^(3+)at the interface of the TiOF_(2)and TiO_(2)under UV-visible(UV-vis)light irradiation.Density functional theory(DFT)calculations and photo/electrochemical measurements further confirmed the electron donor behavior of the Ti^(3+).The benefit is a significantly enhanced charge transfer efficiency in TiOF_(2)/TiO_(2),which not only resulted in improved performances for the photodegradation of acetone being 5.5 times higher than the commercial TiO_(2)but also supported high capacity for sodium-ion storage.Thus,the TiOF_(2)/TiO_(2)with Ti2-F provided a perfect structure to investigate the roles of fluorine sites in fluorinated TiO_(2)systems and their interaction with material properties. | Jie Hu Yi Lu Xiao-Long Liu Christoph Janiak Wei Geng Si-Ming Wu Xiao-Fang Zhao Li-Ying Wang Ge Tian Yuexing Zhang Bao-Lian Su Xiao-Yu Yang | 2020 | CCS Chemistry2020，2，6： | 0 |
| 4 | Extraction of Eugenol from Essential Oils by In Situ Formation of Deep Eutectic Solvents:A Green Recyclable Process显示文摘Eugenol is extensively utilized in chemical industry.In actual production,it is mainly separated from clove essential oils(EOs)through acid-base solutions.In this work,a simple,rapid and effective extraction process was developed for the extraction of eugenol from EOs samples by directly forming deep eutectic solvents(DESs)without using acid-base solutions.The proposed process is designed to dissolve EOs in n-hexane and eugenol was highly selective extracted into DESs with tetrabutylammonium chloride(TBAC).Hydrogen bonds in DESs can be broken by addition of water,resulting in a separation of the two phases,thus obtaining a hydrophobic yellowish eugenol in the upper layer.The quaternary ammonium salt in the lower aqueous solution can be reused after recovery.The most determining influence factors such as the structure of quaternary ammonium salt,the mole ratio of quaternary ammonium salt to eugenol and the amount of n-hexane were investigated.The forming conditions of DESs were studied by Box-Behnken design(BBD).Experiment was carried out under the optimal conditions and good experimental result was demonstrated by the developed process,a high extraction recovery of 92.51% and the purity was about 98.50%,which verifies the excellent performance for the proposed process. | Lingqi Shen Xiangzi Jin Zhihui Zhang Yuexing Yi Jingyu Zhang Zuguang Li | 2024 | Journal of Analysis and Testing2024，8，1： | 0 |
| 5 | Responsive switchable deep eutectic solvents:A review显示文摘Deep eutectic solvents(DESs)have drawn considerable attention as a new type of green solvent since they were reported.Subsequent studies have shown that DESs have the potential to be used as“designable”solvents,which means that the precursors of DESs with different structures and properties can be screened to customize DESs for specific functions.Researchers have found that during the sample preparation process involving DESs,the specific properties of some“smart”DESs can be switched by directing external driving forces,leading to a reversible phase transition of the target solution.These'smart'DESs are called switchable deep eutectic solvents(SDESs).The advent of SDES simplifies the sample pretreatment steps,reduces the use of organic solvents,and makes solvents easy to recycle,which matches the concept of green and sustainable chemistry.Compared with the number of previous experimental studies,the reviews and summaries on SDESs are rare.Therefore,this review made a summary of the concept and research progress of SDESs based on some related works in the past decade,including composition and type,characterization,switching mechanism,etc.It is expected to provide a certain reference and guidance for the subsequent in-depth research of SDESs in the analytical sample pretreatment. | Jingyu Zhang Shang Li Liping Yao Yuexing Yi Lingqi Shen Zuguang Li Hongdeng Qiu | 2023 | Chinese Chemical Letters2023，34，5： | 0 |
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