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| 1 | Human enamel thickness and ENAM polymorphism显示文摘The tooth enamel development gene, enamelin(ENAM), showed evidence of positive selection during a genome-wide scan of human and primate DNA for signs of adaptive evolution. The current study examined the hypothesis that a single-nucleotide polymorphism(SNP) C14625T(rs7671281) in the ENAM gene identified in the genome-wide scan is associated with a change in enamel phenotype. African Americans were selected as the target population, as they have been reported to have a target SNP frequency of approximately 50%, whereas non-Africans are predicted to have a 96% SNP frequency. Digital radiographs and DNA samples from 244 teeth in 133 subjects were analysed, and enamel thickness was assessed in relation to SNP status,controlling for age, sex, tooth number and crown length. Crown length was found to increase with molar number, and females were found to have thicker enamel. Teeth with larger crowns also had thicker enamel, and older subjects had thinner enamel.Linear regression and generalized estimating equations were used to investigate the relationship between enamel thickness of the mandibular molars and ENAM SNP status; enamel in subjects with the derived allele was significantly thinner(P = 0.040)when the results were controlled for sex, age, tooth number and crown length. The derived allele demonstrated a recessive effect on the phenotype. The data indicate that thinner dental enamel is associated with the derived ENAM genotype. This is the first direct evidence of a dental gene implicated in human adaptive evolution as having a phenotypic effect on an oral structure. | Diane M Daubert Joanna L Kelley Yuriy G Udod Carolina Habor Chris G Kleist Ilona K Furman Igor N Tikonov Willie J Swanson Frank A Roberts | 2016 | International Journal of Oral Science2016，8，2： | 2 |
| 2 | Analysis of trace elements in scalp hair of healthy people,hyperplasia and breast cancer patients with XRF method显示文摘 | YURIY K VALENTINA K ALEXANDER C | 2000 | Nuclear Lnstruments and Methods in Physics Research A2000，448，12： | 1 |
| 3 | An investigation of co-fired varistor-ferrite materials 显示文摘 | Aran R Yurii G K Ramesh R | 2004 | Journal of the European Ceramic Society2004，24，： | 1 |
| 4 | Mechanical reinforcement of polymers using carbon nanotubes显示文摘 | JONATHAN N COLEMAN UMAR KHAN YURII K GUN'KO | 2006 | 18(6):689 -7062006，18，6： | 1 |
| 5 | Recent advances in re- search on carbon nanotube-polymer composites 显示文摘 | Michele T Byrne Yurii K Gun' ko | 2010 | Adv Mater2010，22，： | 1 |
| 6 | Acoustic analogue of electronic Bloch oscillations and resonant Zener tunne- ling in ultrasonic superlattices显示文摘 | Helios S A Yuriy A K Jose S D | 2007 | Physical Review Let- ters2007，98，13： | 1 |
| 7 | Kinetics and mechanism of thermal decomposition显示文摘 | Anatolii I K Yurii I R Georgii B M | 1999 | Propellant Explosives Pyrotechnics1999，24，1： | 1 |
| 8 | Multifunctioual magnetic-fluorescent nanocomposites for biomedical applications显示文摘 | Serena A C Yury P R Yurii K G | 2008 | Nanoscale Res Lett2008，3，： | 1 |
| 9 | RAP80/UIMC1 as cancer-associated antigen: Alternative splice variants and their immu- nogenicity显示文摘 | Yuriy V S Ekaterina P K Svetlana V K | 2007 | Cancer Lett2007，255，2： | 1 |
| 10 | Recent advances in research on carbon nanotube polymer composites显示文摘 | Michele T B Yurii K Gun' ko | 2010 | Adv Mater2010，22，15： | 1 |
| 11 | Kinetics and mechanism of thermal decomposition显示文摘 | Anatolii I K Yurii I R Georgii B M | 1999 | Propellant Explosives Pyrotechnics1999，24，： | 1 |
| 12 | Recent advances in research on carbon nanotube-polymer composites显示文摘 | Michele T B Yurii K G | 2010 | Advance Materials2010，22，15： | 1 |
| 13 | A procedure for meaningful unsupervised clustering and its application for solvent classification显示文摘 | Yaroslava P Yuriy K | 2014 | Central European Journal of Chemistry2014，12，5： | 1 |
| 14 | Microstructural Aspects of Grain Growth Kinetics in Non-oriented Electrical Steels显示文摘 | Yuriy S Frantisek K | 2005 | Materials Characterization2005，，55： | 1 |
| 15 | An investigation of cofired varistor-ferrite materials显示文摘 | ARAN R YURII G K RAMESH R | 2004 | Journal of the European Ceramic Society2004，24，7： | 1 |
| 16 | Microstructural aspects of grain growth kinetics in non-oriented electrical steels 显示文摘 | Yuriy S Frantisek K | 2005 | Materials Characterization2005，55，： | 1 |
| 17 | Atomic force microscopy studies of living cells: visualization of motility,division, aggregation, transformation and apoptosis 显示文摘 | Yurii G K Alexander J M Alexander M | 1997 | J Struc Biol1997，120，： | 1 |
| 18 | Small but strong, A review of the mechanical properties of carbon nano- tube显示文摘 | Jonathan N Coleman Umar Khan Yurii K Gun'ko | 2006 | Carbon2006，44，： | 1 |
| 19 | Mechanical rein- forcement of polymers using carbon nanotubes 显示文摘 | Jonathan N Coleman Umar Khan Yurii K Gun' ko | 2006 | Advanced Materi- als2006，18，6： | 1 |
| 20 | Structure of the O-polysaccharide of Aeromonas hydrophila O:34; a case of random O-acetylation of 6-deoxy-L-talose 显示文摘 | Yuriy A K Alexander S S Sofya N S | 2002 | Carbohydr Res2002，337，15： | 1 |
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