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| 1 | Infection-responsive long-term antibacterial bone plates for open fracture therapy显示文摘The infections in open fracture induce high morbidity worldwide.Thus,developing efficient anti-infective orthopedic devices is of great significance.In this work,we designed a kind of infection-responsive long-term antibacterial bone plates.Through a facile and flexible volatilization method,a multi-aldehyde polysaccharide derivative,oxidized sodium alginate,was crosslinked with multi-amino compounds,gentamycin and gelatin,to fabricate a uniform coating on Ti bone plates via Schiff base reaction,which was followed by a secondary crosslinking process by glutaraldehyde.The double-crosslinked coating was stable under normal condition,and could responsively release gentamycin by the triggering of the acidic microenvironment caused by bacterial metabolism,owning to the pH-responsiveness of imine structure.The thickness of the coating was ranging from 22.0μm to 63.6μm.The coated bone plates(Ti-GOGs)showed infection-triggered antibacterial properties(>99%)and high biocompatibility.After being soaked for five months,it still possessed efficient antibacterial ability,showing its sustainable antibacterial performance.The in vivo anti-infection ability was demonstrated by an animal model of infection after fracture fixation(IAFF).At the early stage of IAFF,Ti-GOGs could inhibit the bacterial infection(>99%).Subsequently,Ti-GOGs could promote recovery of fracture of IAFF.This work provides a convenient and universal strategy for fabrication of various antibacterial orthopedic devices,which is promising to prevent and treat IAFF. | Lujiao Zhang Yurun Yang Yan-Hua Xiong Yu-Qing Zhao Zongpeng Xiu Hui-Min Ren Kai Zhang Shun Duan Ying Chen Fu-Jian Xu | 2023 | Bioactive Materials2023，，7： | 2 |
| 2 | Flow-restricted Etching Method on Isotropic Substrates and Its Mechanism显示文摘With the development of analytical instrumentation to minimization,integration and automation,the microfluidic chips,which are more integrated,complex and diversified,have been applied widely on the manufacturing of analytical instrumentation.However,the present photolithography-based microfabrication technology,which is only able to pattern microchannels with simple inside structures,can not follow the rapid development of requirements.For solving the problem,a fabrication method based on the restricting effect of laminar flow is proposed for the micro etching on isotropic substrates.Experiments were conducted inside glass-based microchannels,in which certain etchant was used to form complicated microstructures.The flow parameters' effects on the aspect ratio,side wall profile and etching rate were revealed by the experiments.The experimental results reveal that the topography of micro structures patterned with the restricted flow etching method is mainly determined by the flowrates of separator and etchant.The computational fluid dynamics(CFD) model on the interface between multiple streams was established for the etching process,and analysis on the causes of various micro topographies was conducted based on the CFD simulation results.The experimental data consisted with the simulation results very well.The investigation depicted in this paper indicate that the flow restricted etching method provides sufficient references for the research and understanding on the mass transport at the liquid-liquid surface in the microchannel and can be used to pattern complex micro structures with high aspect ratios,meantime,it greatly enriches the microfabrication technology for microfluidic chips. | XIE Haibo ZHENG Yi FAN Yurun FU Xin YANG Huayong | 2010 | Chinese Journal of Mechanical Engineering2010，23，5： | 1 |
| 3 | Sorption and diffusion of ethanoi vapor in polybutadiene/acrylonitrile,polybutadiene/styrene and polybutadiene based polyurethanes显示文摘 | Yurun Yang Yongmin Huang Dening Wang Honglai Liu Chunpu Hu | 2004 | European Polymer Journal2004，，40： | 1 |
| 4 | Stress boundary layers in the viscoelastic flow past a cylinder in a channel:limiting solutions显示文摘The flow past a cylinder in a channel with the aspect ratio of 2: 1 for the upper convected Maxwell (UCM) fluid and the Oldroyd-B fluid with the viscosity ratio of 0.59is studied by using the Galerkin/Least-square finite element method and a p-adaptive refinement algorithm. A posteriori error estimation indicates that the stress-gradient error dominates the total error. As the Deborah number, De, approaches 0.8 for the UCM fluid and 0.9 for the Oldroyd-B fluid, strong stress boundary layers near the rear stagnation point are forming, which are characterized by jumps of the stress-profiles on the cylinder wall and plane of symmetry, huge stress gradients and rapid decay of the gradients across narrow thicknesses. The origin of the huge stress-gradients can be traced to the purely elongational flow behind the rear stagnation point, where the position at which the elongation rate is of 1/2De approaches the rear stagnation point as the Deborah number approaches the critical values. These observations imply that the cylinder problem for the UCM and Oldroyd-B fluids may have physical limiting Deborah numbers of 0.8 and 0.9, respectively. | Yurun Fan Huayong Yang Roger I. Tanner | 2005 | Acta Mechanica Sinica2005，21，4： | 1 |
| 5 | Characterizations of high-voltage vertically-stacked GaAs laser power converter显示文摘Six-junction vertically-stacked Ga As laser power converters(LPCs) with n^+-Ga As/p^+-Al0.37 Ga0.63 As tunnel junctions have been designed and grown by metal-organic chemical vapor deposition for converting the power of 808 nm lasers. The LPC chips are characterized by measuring current–voltage(I–V) characteristics under 808 nm laser illumination, and a maximum conversion efficiency ηc of 53.1% is obtained for LPCs with an aperture diameter of 2 mm at an input laser power of 0.5 W. In addition, the characteristics of the LPCs are analyzed by a standard equivalent-circuit model, and the reverse saturation current, ideality factor, series resistance and shunt resistance are extracted by fitting of the I–V curves. | Jie Huang Yurun Sun Yongming Zhao Shuzhen Yu Kuilong Li Jianrong Dong Jiping Xue Chi Xue Yang Ye | 2018 | Journal of Semiconductors2018，39，9： | 1 |
| 6 | Gas Permeability and Free Volume Hole Properties of Interpenetrating Polymer Network Studied by Positrons显示文摘A series of polyurethane/epoxy resin interpenetrating polymer networks (PU/ER IPN) were studied by positron annihilation lifetime spectroscopy (PALS). The effects of epoxy resin type and content on the free volume properties in IPN were investigated. We found that in PU/ER IPN, the free volume hole size and fractional free volume showed a negative deviation due to closer segmental chain packing through some chemical bonding between PU and epoxy resin. Direct relationship between the gas permeability and the free volume has been established based on the free volume theory. Experimental results revealed that the free volume plays an important role in determining the gas diffusion and permeability. | QI Ning GONG Wei WANG Zhifen WANG Bo YANG Yurun HU Chunpu | 2007 | Wuhan University Journal of Natural Sciences2007，12，2： | 0 |
| 7 | Toughening of vinyl ester resins by two-dimensional MXene nanosheets显示文摘Two-dimensional nanosheets are highly effective tougheners for vinyl ester resins.The toughening effect is related to the high specific surface area and unique two-dimensional planar structure of the nanosheets.In this study,a coupling agentγ-(2,3-epoxypropoxy)propytrimethoxysilane(Kh-560)was used to modify MXene nanosheets(M-MXene)for use in toughening vinyl ester resin.The mechanical properties,including the tensile strength,flexural strength,Young’s modulus and elongation,of neat vinyl ester resin and vinyl ester resin modified with MXene and M-MXene were investigated.The results showed that modification significantly improved the mechanical properties of the vinyl ester resin.The tensile and flexural strengths of the MXene-nanosheet-modified vinyl ester resin were 27.20%and 25.32%higher,respectively,than those of the neat vinyl ester resin.The coupling agent improved the interfacial compatibility between the MXene nanosheets and vinyl ester resin,which resulted in the tensile and flexural strengths of the M-MXene-nanosheet-modified vinyl ester resin being 52.57%and 54.60%higher,respectively,than those of the neat vinyl ester resin for a loading quantity of nanosheets of only 0.04 wt%,which is economically viable.The main mechanisms by which the nanosheets toughen the resin are crack deflection and crack pinning. | Yurun Dai Heng Fang Zong Lu Zhuohong Yang Yanying Wei | 2022 | Frontiers of Chemical Science and Engineering2022，16，11： | 0 |
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