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| 1 | High doses of α-galactosylceramide potentiate experimental autoimmune encephalomyelitis by directly enhancing Th17 response显示文摘伪 - Galactosylceramide (伪 - GC ) 广泛地被知道激活不变的自然漂亮 T (iNKT ) 压制髓磷脂的房间抗原特定的 Th1 回答,保护易受影响的老鼠免于试验性的自体免疫的脑脊髓炎(EAE ) 。这里,我们表明那高加重,而非改善的伪 - GC 开 EAE 的意外发现。当与高剂量的伪 - GC 对待的 MOG35-55-specific T 房间被变成 na 时,类似的结果被观察 ? ve syngeneic 接受者老鼠。进一步的学习证明伪 - GC 的高剂量直接通过 STAT3 的 phosphorylation 和 NF-魏 B 的激活由 CD4+CD44+ 记忆 T 房间的激活提高 Th17 和 Th1 反应。不同于由伪 - GC 的低剂量的 iNKT 房间的激活,伪 - GC 的高剂量直接交往了, CD1d 在 T 房间上表示了并且激活 Th17 和 Th1 房间。而且,介绍抗原的房间(APC ) 主要表示 CD1d1,而 CD4+ T 房间快车 CD1d2 的多数。由 RNAi 的 CD1d1 或 CD1d2 基因表示击倒分别地防碍 iNKT 或 Th17/Th1 房间的激活。因此,伪 - GC 处理能改善或变得更坏由雇佣取决于剂量的 APC 或 Th17/Th1 房间的 EAE 使用了。 | Gaochao Qian Xia Qin Ying Qin Zang Baoxue Ge Taylor B Guo Bing Wan Lei Fang Jingwu Z Zhang | 2010 | Cell Research2010，20，4： | 3 |
| 2 | Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore显示文摘 | Tian Tian Xiaorun Li Yingying Liu Chengliang Wang Xing Liu Guoqiang Bi Xuan Zhang Xuebiao Yao Z Hong Zhou Jianye Zang | 2018 | Cell Research2018，28，3： | 2 |
| 3 | Structural and PL Properties of Cu-doped ZnO Films显示文摘 | Peng X P Xu J Z Zang H | 2008 | Journal of Luminescence2008，128，： | 1 |
| 4 | Influence of Fe203 doping on mi- crostructural and electrical properties of ZnO - Pr O based varistor ceramic materials显示文摘 | Peng Z Fu X Zang Y | 2010 | Journal of Alloys and Com- pounds2010，508，2： | 1 |
| 5 | Enhanced specific immune responses by CpG DNA in mice immunized with recombinant hepatitis B surface antigen and HB vaccine 显示文摘 | Zang X He P Hu Z | 2011 | Virol J2011，8，： | 1 |
| 6 | Electrochemical detection of dopamine using water-soluble sulfonated graphene显示文摘 | Li S J He J Z Zang M J | 2013 | Electro- chimica Acta2013，102，： | 1 |
| 7 | Semi-infinite linear programming:A unified approach to digital filter design with timeand frequency-domain specifications显示文摘 | Nordebo S Zang Z | 1999 | IEEE Trans Circuit and Systems Ⅱ:Analog and Digital SignalProcessing1999，46，6： | 1 |
| 8 | Coverage-dependentstructures of cobalt-phthalocyanine molecules adsorbedon Cu(001) surface显示文摘 | Guo Q M Qin Z H Zang K | 2010 | Langmuir2010，26，11： | 1 |
| 9 | miR-155 inhibits the sensitiv- ity of lung cancer cells to cisplatin via negative regulation of Apaf-1 expression 显示文摘 | Zang YS Zhong YF Fang Z | 2012 | Cancer Gene Ther2012，19，11： | 1 |
| 10 | Nitrogen doping in cuprous oxide films synthesized by radical oxidation at low temperature显示文摘 | ZANG Z NAKAMURA A TEMMYO J | 2013 | Materials Letters2013，92，3： | 1 |
| 11 | Experimental investigation of the immunoregulatory and anti- inflammatory effects of the traditional Chinese medicine ' Li-Yan Zhi- Ke Granule' for relieving chronic pharyngitis in rats显示文摘 | Sun Y Zang Z Xu X Zhang Z Zhong L Zan W Zhao Y Sun L | 2011 | Molecular Biology Reports2011，38，1： | 1 |
| 12 | Structural insights into histone demethylation by JMJD2 family members显示文摘 | Chen Z Zang J Whetstine J | 2006 | Cell2006，125，4： | 1 |
| 13 | 查看详情显示文摘 | Wang W N Li Y P Wu Q H Wang C Zang X H Wang Z | | 0，，03： | 1 |
| 14 | Bum injury promotes antigendriven Th2-type responses in vivo 显示文摘 | Guo Z Kavanagh E Zang Y | 2003 | J Immunol2003，171，8： | 1 |
| 15 | Migration,speciation and distribution of heavy metals in an oil-polluted soil affected by crude oil extraction processes显示文摘 | FU X W CUI Z J ZANG G L | 2014 | Environmental Science:Processes & Impacts2014，16，7： | 1 |
| 16 | Direction of Departure (DOD) and Direction of Arrival (DOA) Estimation in MIMO Radar with Reduced- Dimension MUSIC 显示文摘 | ZANG X F XU L Y XU D Z | 2010 | IEEE Commun Letters2010，14，12： | 1 |
| 17 | Normobaric hypoxia training causes more weight loss than normoxia training after a 4-week residential camp for obese young adults显示文摘 | Kong Z Zang Y Hu Y | 2014 | Sleep Breath2014，18，3： | 1 |
| 18 | Effect of aluminum on mi- crostructure of HP40 steel 显示文摘 | LIU Z Y LA P Q ZANG L | 2007 | Journal of Iron and Steel Re- search International2007，14，5： | 1 |
| 19 | Differential proteomics identificationof HSP90 as potential serum biomarker in hepatocellular carcinoma bytwo-dimensional electrophoresis and mass spectrometry 显示文摘 | SUN Y ZANG Z XU X | 2010 | Int J MolSci2010，11，4： | 1 |
| 20 | 查看详情显示文摘 | Wang L Zang X H Chang Q Y Zhang G J Wang C Wang Z | | 0，，： | 1 |
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