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| 1 | Isolation and initial characterization of GW5, a major QTL associated with rice grain width and weight显示文摘谷物重量是庄稼谷物产量的一个主要决定因素并且被自然地发生的量的特点 loci (QTL ) 控制。我们更早识别了控制米饭谷物宽度和重量的主要 QTL, GW5,它在米饭染色体 5 上被印射到一个再结合热点。获得 GW5 怎么控制米饭谷物宽度的更好的理解,我们进行了这个地点的好印射并且揭开在米饭栽培变种 Asominori 与增加的谷物宽度联系的 1 212-bp 删除,与苗条谷物米饭 IR24 比较。另外, 46 米饭栽培变种的 genotyping 分析表明这删除高度与谷物宽度显型被相关,建议 GW5 删除可能在米饭驯服期间被选择了。GW5 编码对原子核局部性的 144 氨基酸的新奇原子蛋白质。而且,我们证明 GW5 身体上在酵母与 polyubiquitin 交往二混血儿的试金。一起,我们的结果建议 GW5 代表主要 QTL 内在的米饭宽度和重量,并且它多半在 ubiquitin-proteasome 小径行动在种子开发期间调整房间分割。这研究提供新奇卓见进控制米饭谷物开发的分子的机制并且建议 GW5 能为庄稼的产量很高的繁殖用作一个潜在的工具。 | Jianfeng Weng Suhai Gu Xiangyuan Wan He Gao Tao Guo Ning Su Cailin Lei Xin Zhang Zhijun Cheng Xiuping Guo Jiulin Wang Ling Jiang Huqu Zhai Jianmin Wan | 2008 | Cell Research2008，18，12： | 248 |
| 2 | Safety threshold of high-speed railway pier settlement based on train-track-bridge dynamic interaction显示文摘This paper presents a method to determine the safety threshold of bridge pier settlement in high-speed railways.An analytical expression of the mapping relationship between the pier settlement and the rail deformation is derived theoretically for the double block ballastless track-bridge system.By adopting the superposition of the track random irregularity and the rail deformation caused by the pier settlement as the excitation inputs,the variations of vehicle dynamics indices with pier settlement are comparatively analyzed.Then,the safety threshold of the bridge pier settlement is obtained according to the limit of vehicle running safety and ride comfort indices of the high-speed trains.Results show that the dynamics indices of different trains have different sensitivities to the pier settlement,and the train CRH2C is the most sensitive one among all the types of Chinese high-speed trains.When passing through the bridges in common span with pier settlement at the speed of 250–350 km/h,the trains suffer the low-frequency excitations,and the vertical acceleration of car body is most sensitive to the pier settlement of all the dynamics indices.When the car body vertical acceleration just exceeds the allowable limit,the critical settlement value is 23.4 mm,which is much bigger than the pier differential settlement limit in the current code for Chinese high-speed railways. | CHEN Zhao Wei ZHAI Wan Ming CAI Cheng Biao SUN Yu | 2015 | Science China(Technological Sciences)2015，58，2： | 26 |
| 3 | Isolation and characterization of dengue virus serotype 2 from the large dengue outbreak in Guangdong, China in 2014显示文摘Dengue has been well recognized as a global public health threat,but only sporadic epidemics and imported cases were reported in recent decades in China.Since July 2014,an unexpected large dengue outbreak has occurred in Guangdong province,China,resulting in more than 40000 patients including six deaths.To clarify and characterize the causative agent of this outbreak,the acute phase serum from a patient diagnosed with severe dengue was subjected to virus isolation and high-throughput sequencing(HTS).Traditional real-time RT-PCR and HTS with Ion Torrent PGM detected the presence of dengue virus serotype 2(DENV-2).A clinical DENV-2 isolate GZ05/2014 was obtained by culturing the patient serum in mosquito C6/36 cells.The complete genome of GZ05/2014 was determined and deposited in Gen Bank under the access number KP012546.Phylogenetic analysis based on the complete envelope gene showed that the newly DENV-2 isolate belonged to Cosmopolitan genotype and clustered closely with other Guangdong strains isolated in the past decade.No amino acid mutations that are obviously known to increase virulence or replication were identified throughout the genome of GZ05/2014.The high homology of Guangdong DENV-2 strains indicated the possibility of establishment of local DENV-2 circulation in Guangdong,China.These results help clarify the origin of this epidemic and predict the future status of dengue in China. | ZHAO Hui ZHAO Ling Zhai JIANG Tao LI Xiao Feng FAN Hang HONG Wen Xin ZHANG Yu ZHU Qin YE Qing TONG Yi Gang CAO Wu Chun ZHANG Fu Chun QIN Cheng Feng | 2014 | Science China(Life Sciences)2014，57，12： | 21 |
| 4 | Inhibition of KLF7-Targeting Micro RNA 146b Promotes Sciatic Nerve Regeneration显示文摘A previous study has indicated that Krüppel-like factor 7(KLF7), a transcription factor that stimulates Schwann cell(SC) proliferation and axonal regeneration after peripheral nerve injury, is a promising therapeutic transcription factor in nerve injury. We aimed to identify whether inhibition of micro RNA-146 b(mi R-146 b)affected SC proliferation, migration, and myelinated axon regeneration following sciatic nerve injury by regulating its direct target KLF7. SCs were transfected with mi RNA lentivirus, mi RNA inhibitor lentivirus, or KLF7 si RNA lentivirus in vitro. The expression of mi R146 b and KLF7,as well as SC proliferation and migration, were subsequently evaluated. In vivo, an acellular nerve allograft(ANA) followed by injection of GFP control vector or a lentiviral vector encoding an mi R-146 b inhibitor was used to assess the repair potential in a model of sciatic nerve gap. mi R-146 b directly targeted KLF7 by binding to the 30-UTR, suppressing KLF7. Up-regulation of mi R-146 b and KLF7 knockdown significantly reduced the proliferation and migration of SCs, whereas silencing mi R-146 b resulted in increased proliferation and migration. KLF7 protein was localized in SCs in which mi R-146 b was expressed in vivo.Similarly, 4 weeks after the ANA, anti-mi R-146 b increased KLF7 and its target gene nerve growth factor cascade, promoting axonal outgrowth. Closer analysis revealed improved nerve conduction and sciatic function index score, and enhanced expression of neurofilaments, P0(anti-peripheral myelin), and myelinated axon regeneration. Our findings provide new insight into the regulation of KLF7 by mi R-146 b during peripheral nerve regeneration and suggest a potential therapeutic strategy for peripheral nerve injury. | Wen-Yuan Li Wei-Ting Zhang Yong-Xia Cheng Yan-Cui Liu Feng-Guo Zhai Ping Sun Hui-Ting Li Ling-Xiao Deng Xiao-Feng Zhu Ying Wang | 2018 | Neuroscience Bulletin2018，34，3： | 19 |
| 5 | Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma显示文摘Esophageal squamous cell carcinoma(ESCC)is a poor-prognosis cancer type with limited understanding of its molecular etiology.Using 508 ESCC genomes,we identified five novel significantly mutated genes and uncovered mutational signature clusters associated with metastasis and patients’outcomes.Several functional assays implicated that NFE2L2 may act as a tumor suppressor in ESCC and that mutations in NFE2L2 probably impaired its tumor-suppressive function,or even conferred oncogenic activities.Additionally,we found that the NFE2L2 mutations were significantly associated with worse prognosis of ESCC.We also identified potential noncoding driver mutations including hotspot mutations in the promoter region of SLC35E2 that were correlated with worse survival.Approximately 5.9%and 15.2%of patients had high tumor mutation burden or actionable mutations,respectively,and may benefit from immunotherapy or targeted therapies.We found clinically relevant coding and noncoding genomic alterations and revealed three major subtypes that robustly predicted patients’outcomes.Collectively,we report the largest dataset of genomic profiling of ESCC useful for developing ESCC-specific biomarkers for diagnosis and treatment. | Yongping Cui Hongyan Chen Ruibin Xi Heyang Cui Yahui Zhao Enwei Xu Ting Yan Xiaomei Lu Furong Huang Pengzhou Kong Yang Li Xiaolin Zhu Jiawei Wang Wenjie Zhu Jie Wang Yanchun Ma Yong Zhou Shiping Guo Ling Zhang Yiqian Liu Bin Wang Yanfeng Xi Ruifang Sun Xiao Yu Yuanfang Zhai Fang Wang Jian Yang Bin Yang Caixia Cheng Jing Liu Bin Song Hongyi Li Yi Wang Yingchun Zhang Xiaolong Cheng Qimin Zhan Yanhong Li Zhihua Liu-Show | 2020 | Cell Research2020，30，10： | 19 |
| 6 | Analysis on Dry Matter Production Characteristics of Super Hybrid Rice显示文摘Six middle-season indica hybrid rice combinations, including five super hybrid rice combinations with the high yield about 10.5 t/ha and a check hybrid rice combination Shanyou 63 with a yield potential about 9.5 t/ha, were used as materials to study the dry matter production characteristics. The super hybrid rice showed a high ability in dry matter production and accumulation and its yield enhanced with the increase of dry matter accumulation. The advantage period of dry matter production in the super hybrid rice was mainly at the middle and late growth stages compared with the check. The grain yield had no significant correlation with the dry matter accumulation before the elongation stage while had a significantly positive correlation with the dry matter accumulation from the elongation to maturity stages in super hybrid rice. There were more dry matter in vegetative organs at the heading stage in the super hybrid rice but its contribution to yield (apparent conversion percentage) was averagely 4.3 percent points lower than that in the check. For crop growth rate (CGR), the comparative advantage of super hybrid rice was at the middle and late stages, especially after flowering. Moreover, as the rising of leaf area index (LAI) and leaf area duration (LAD), CGR enhanced. The total LAD and the mean of LAD per day of super hybrid rice was about 14.79% and 10.31% higher than those of the check, respectively. The results indicate that the high yield of super hybrid rice mostly comes from the products of photosynthesis after heading, which is shown by the increased CGR at middle and later stages. It is suggested that LAD character might be used to better explain the advantage in the dry matter production of super hybrid rice than LAI. | WU Wen-ge ZHANG Hong-cheng QIAN ZHAI Chao-qun DAI Qi-gen Ying-fei CHENG Ye Wu Gui-cheng | 2008 | Rice science2008，15，2： | 16 |
| 7 | Study of glue extrusion after endoscopic N-butyl-2-cyanoacrylate injection on gastric variceal bleeding显示文摘AIM:To investigate glue extrusion after endoscopic N-butyl-2-cyanoacrylate injection on gastric variceal bleeding and to evaluate the long-term efficacy and safety of this therapy.METHODS:A total of 148 cirrhotic patients in our hospital with esophagogastric variceal bleeding(EGVB) were included in this study.N-butyl-2-cyanoacrylate was mixed with lipiodol in a 1:1 ratio and injected as a bolus of 1-3 mL according to variceal size.Patients underwent endoscopic follow-up the next week,fourth week,second month,fourth month,and seventh month after injection and then every 6 mo to determine the cast shape.An abdominal X-ray fi lm and ultrasound or computed tomographic scan were also carried out in order to evaluate the time of variceal disappearance and complete extrusion of the cast.The average follow-up time was 13.1 mo.RESULTS:The instantaneous hemostatic rate was 96.2%.Early re-bleeding after injection in 9 cases(6.2%) was estimated from rejection of adhesive.Late re-bleeding occurred in 12 patients(8.1%) at 2-18 mo.The glue cast was extruded into the lumen within one month in 86.1% of patients and eliminated within one year.Light erosion was seen at the injection position and mucosa edema in the second week.The glue casts were extruded in 18 patients(12.1%) after one week and in 64 patients(42.8%) after two weeks.All kinds of glue clumping shapes and colors on endoscopic examination were observed in 127 patients(86.1%) within one month,including punctiform,globular,pillar and variform.Forty one patients(27.9%) had glue extrusion after 3 mo and 28 patients(28.9%) after six months.The extrusion time was not related to the injection volume of histoacryl.Obliteration was seen in 70.2%(104 cases) endoscopically.The main complication was re-bleeding resulting from extrusion.The prognosis of the patients depended on the severity of the underlying liver disease.CONCLUSION:Endoscopic injection of cyanoacrylate is highly effective for gastric varices bleeding.The glue clump shape is correlated with anatomic structure of vessels.The time of extrusion was not related to dosage of the glue. | Yan-Mei Wang Liu-Fang Cheng Nan Li Kai Wu Jun-Shan Zhai Ya-Wen Wang | 2009 | World Journal of Gastroenterology2009，15，39： | 13 |
| 8 | Guiding-controlling technology of coal seam hydraulic fracturing fractures extension显示文摘Aiming at the uncontrollable problem of extension direction of coal seam hydraulic fracturing,this study analyzed the course of fractures variation around the boreholes in process of hydraulic fracturing,and carried out the numerical simulations to investigate the effect of artificial predetermined fractures on stress distribution around fractured holes.The simulation results show that partial coal mass occurs relatively strong shear failure and forms weak surfaces,and then fractures extended along the desired direction while predetermined fractures changed stress distribution.Directional fracturing makes the fractures link up and the pressure on coal mass is relieved within fractured regions.Combining deep hole controlling blasting with hydraulic fracturing was proposed to realize the extension guiding-controlling technology of coal seam fractures.Industrial experiments prove that this technology can avoid local stress concentration and dramatically widen the pressure relief scope of deep hole controlling blasting.The permeability of fractured coal seam increased significantly,and gas extraction was greatly improved.Besides,regional pressure relief and permeability increase was achieved in this study. | Zhai Cheng Li Min Sun Chen Zhang Jianguo Yang Wei Li Quangui | 2012 | International Journal of Mining Science and Technology2012，22，6： | 12 |
| 9 | Effect of roadway turnings on gas explosion propagation characteristics in coal mines显示文摘In order to reveal the effect of turnings on explosion propagation, experiments were performed in three different pipes (single bend, U-shaped pipe and Z-shaped pipe). Flame and pressure transducers were used to track the velocity at the explosion front. When the pipes were filled with methane, the explosion strength was significantly enhanced due to the turbulence induced by increasing the number of turnings, while the flame speed (S f) and peak overpressure (DP max) increased dramatically. In addition, the strength of the explosion increased in violence as a function of the number of turnings. However, when the bend was without methane, the turnings weakened the strength of the explosion compared with the ordinary pipe, shown by the decrease in the values of DP max and S f . In addition, the propagation characteristics in a U-shaped pipe were similar to those in a Z-shaped pipe and the values of DP max and S f were also close. The results show that the explosion propagation characteristics largely depend on gas distribution in the pipes and the number of turnings. The different directions of the turnings had no effect. | Zhu Chuanjie Lin Baiquan Ye Qing Zhai Cheng | 2011 | Mining Science and Technology2011，21，3： | 12 |
| 10 | Genome Characteristics and Evolution of Pseudorabies Virus Strains in Eastern China from 2017 to 2019显示文摘Since late 2011,outbreaks of pseudorabies virus(PRV)have occurred in southern China causing major economic losses to the pig industry.We previously reported that variant PRV forms and recombination in China could be the source of continued epidemics.Here,we analyzed samples from intensive pig farms in eastern China between 2017 and 2019,and sequenced the main glycoproteins(gB,gC,gD,and gE)to study the evolution characteristics of PRV.Based on the gC gene,we found that PRV variants belong to clade 2 and detected a founder effect during by the PRV epidemic.In addition,we detected inter-and intra-clade recombination;in particular,inter-clade recombination in the gB genes of strains FJ-ZXF and FJ-W2,which were recombinant with clade 1 strains.We also found specific amino-acid changes and positively selected sites,possibly associated with functional changes.This analysis of the emergence of PRV in China illustrates the need for continuous monitoring and the development of vaccines against specific variants of PRV. | Xiaofeng Zhai Wen Zhao Kemang Li Cheng Zhang Congcong Wang Shuo Su Jiyong Zhou Jing Lei Gang Xing Haifeng Sun Zhiyu Shi Jinyan Gu | 2019 | Virologica Sinica2019，34，6： | 12 |
| 11 | Variable frequency of pulse hydraulic fracturing for improving permeability in coal seam显示文摘Variable frequency,a new pattern of pulse hydraulic fracturing,is presented for improving permeability in coal seam.A variable frequency pulse hydraulic fracturing testing system was built,the mould with triaxial loading was developed.Based on the monitor methods of pressure sensor and acoustic emission,the trials of two patterns of pulse hydraulic fracturing of single frequency and variable frequency were carried out,and at last fracturing mechanism was analyzed.The results show that the effect of variable frequency on fracture extension is better than that of single frequency based on the analysis of macroscopic figures and AE.And the shortage of single frequency is somewhat remedied when the frequency is variable.Under variable frequency,the pressure process can be divided into three stages:low frequency band,pressure stability band and high frequency band,and rupture pressure of the sample is smaller than that of the condition of single frequency.Based on the Miner fatigue theory,the effect of different loading sequences on sample rupture is discussed and the results show that it is better to select the sequence of low frequency at first and then high frequency.Our achievements can give a basis for the improvement and optimization of the pulse hydraulic fracturing technology. | Li Quangui Lin Baiquan Zhai Cheng Ni Guanhua Peng Shen Sun Chen Cheng Yanying | 2013 | International Journal of Mining Science and Technology2013，23，6： | 12 |
| 12 | Plasma-induced nanowelding of a copper nanowire network and its application in transparent electrodes and stretchable conductors显示文摘铜 nanowires (Cu NW ) 由于他们的突出的电的性质和低费用为电子学作为积木吸引了增加的注意。然而,无所不在地在 Cu NW 的表面上存在的器官的残余和氧化物层阻碍好内部电线的接触。象热退火和酸处理那样的通常使用的方法经常导致 nanowire 损坏。此处,在房间温度的氢血浆处理被表明了为同时的表面在连接清洗并且选择焊接 Cu NW 有效。有优秀光电的性能的透明电极(19 O 汯獹獩琠浥数慲畴敲漠 ??? ‰ ???????璪?? | Ranran Wang Haitao Zhai Tao Wang Xiao Wang Yin Cheng Liangjing Shi Jing Sun | 2016 | Nano Research2016，9，7： | 11 |
| 13 | A new technology for coal and gas control based on the in situ stress distribution and the roadway layout显示文摘An auxiliary gas control technology is described that can reduce coal and gas outburst accidents when there is no existing protective coal seam and gas pre-draining is not effective.Numerical simulation methods were used to study the stress distribution ahead of the roadway face for different in situ stresses.The results from the simulation can then provide a new gas control technology.The results show that a high stress concentration,high stresses,and high displacement gradients appear ahead of the roadway face when the maximum in situ stress is aligned perpendicular to the roadway axis.The risk of gas outburst is higher when the stresses decrease rapidly over distance and when the release of more energy occurs immediately after driving the roadway.The gas outburst risk is much smaller when the in situ stress is aligned parallel to the roadway axis.During design of the coal mine most of the coal roadways should be arranged to parallel the maximum in situ stress.This will decrease the outburst risk in general and may be considered a new gas outburst prevention method. | Yang Wei Lin Baiquan Zhai Cheng Li Xianzhong Sun Xin Zhang Chao | 2012 | International Journal of Mining Science and Technology2012，22，2： | 11 |
| 14 | Effect of High Suspension and Low Incision Surgery Based on Traditional Ligation of Chinese Medicine in Treatment of Mixed Haemorrhoids:A Multi-centre,Randomized,Single-Blind,Non-inferiority Clinical Trial显示文摘Objective:To observe the clinical effect of high suspension and low incision(HSLI)surgery on mixed haemorrhoids,compared with Milligan-Morgan haemorrhoidectomy.Methods:A multi-centre,randomized,singleblind,non-inferiority clinical trial was performed.Participants with mixed haemorrhoids from Xiyuan Hospital of China Academy of Chinese Medical Sciences,Beijing Rectum Hospital,Air Force Medical Center of People's Liberation Army of China,and Puyang Hospital of Traditional Chinese Medicine were enrolled from September 2016 to March 2018.By using a blocked randomization scheme,participants were assigned to two groups.The experimental group was treated with HSLI,while the control group was treated with Milligan-Morgan haemorrhoidectomy.The primary outcome was the clinical effect evaluated at 12 weeks after operation.The secondary outcomes included the number of haemorrhoids treated during the operation,pain scores,use of analgesics,postoperative oedema,wound healing,incidence of anal stenosis,anorectal manometry after operation,as well as surgical duration,length of stay and total hospitalization expenses.A safety evaluation was also conducted.Results:In total,246 eligible participants were enrolled,with 123 cases in each group.There was no significant difference in the clinical effect between the two groups(100.00% vs.99.19%,P>0.05).Compared with the control group,the number of external haemorrhoids treated during the operation and the pain scores after operation were significantly reduced in the experimental group(P<0.05 or P<0.01);the patient number with wound healing at 2 weeks after operation and the functional length of anal canal at 12 weeks after operation were significantly increased in the experimental group(P<0.05).There was no significant difference in the incidence of anal stenosis,the numbers of patients using analgesics and patients with postoperative oedema between the two groups after operation(P>0.05).The surgical duration and length of stay in the experimental group were significantly longer than those in the control group,and the total hospitalization expense was significantly higher than that in the control group(all P<0.05).No adverse events were reported in either group during the whole trial or follow-up period.Conclusion:HSLI had the advantages of preserving the skin of anal canal completely,alleviating postsurgical pain and promoting rapid recovery after operation.(Registration No.Chi CTR1900022883). | JIA Xiao-qiang CAO Wei-wei QUAN Long-fang ZHAO Wei-bing CHENG Fang JIA Shan FENG Liu-quan WEI Xu-feng XIE Zhen-nian WANG Dong XU Chun-yan CUI Chun-hui CAI Xing-juan HE Lan-ye WANG Zhan-jun TIAN Ying SHI Shu-min SUN Si-miao SU Liang ZHAI Meng-fan | 2021 | Chinese Journal of Integrative Medicine2021，27，9： | 11 |
| 15 | Over-production of nitric oxide by oxidative stress- induced activation of the TGF-β1/PI3K/Akt pathway in mesangial cells cultured in high glucose显示文摘 | Yun-peng ZHAI Qian LU Yao-wu LIU Qian CHENG Ya-qin WEI Fan ZHANG Cheng-lin LI Xiao-xing YIN | 2013 | Acta Pharmacologica Sinica2013，34，4： | 11 |
| 16 | A numerical simulation of the influence initial temperature has on the propagation characteristics of, and safe distance from, a gas explosion显示文摘A model roadway with a cross-sectional area of 80 mm 80 mm and a length of 100 m was used to estimate the overpressure, the temperature, the density, and the combustion rate during an explosion. Auto-ReaGas software was used for the calculations and the initial temperatures were 248, 268, 308, or 328 K. The methaneair mixture had a fuel concentration of 9.5% and the tunnel had a filling ratio of 10%. The results show that the safe distance necessary to avoid harm from the shock wave increases with increasing initial temperature. The distance where the peak overpressure begins to rise, and where the maximum value occurs, increases as the initial temperature increases. These are almost linear functions of the initial temperature. At locations before shock wave attenuation has occurred increasing the initial temperature linearly increases the maximum temperature at each point following along the tunnel. At the same time, the peak overpressure, the maximum density, and the maximum combustion rate decrease linearly. How-ever, after the shock wave has attenuated the attenuation extent of the peak overpressure decreases with an increase in initial temperature. The influence of the initial temperature on the explosion propagation depends on the combined effects of inhibiting and enhancing factors. The research results can provide a theoretical guidance for gas explosion disaster relief and treatment in underground coal mines. | Jiang Bingyou Lin Baiquan Shi Shulei Zhu Chuanjie tiu Qian Zhai Cheng | 2012 | International Journal of Mining Science and Technology2012，22，3： | 10 |
| 17 | Application of pressure relief and permeability increased by slotting a coal seam with a rotary type cutter working across rock layers显示文摘Pressure relief to increase permeability significantly improves gas extraction efficiency from coal seams.In this paper we report results from simulations using FLAC 3D code to analyze changes in coal displacement and stress after special drill slots were formed.We investigated the mechanism of pressure relief and permeability increase in a high-gas and low-permeability coal seam through the modeling of gas flow.This allows the development of the technology.Slotting across rock layers in the coal seam with a rotary type cutter was then applied in the field.The results show that pressure relief and permeability increases from slotting the coal seam can increase the transport and the fracture of the coal.This expands the range of pressure relief from the drilling and increases the exposed area of the seam.The total quantity of gas extracted from slotted bore holes was three times that seen with ordinary drilling.The concentration of gas extracted from the slotted drills was from two to three times that seen using ordinary drills.The gas flow was stable at 80%.Improved permeability and more efficient gas extraction are the result of the slotting.The roadway development rate is increased by 30-50% after gas drainage.This technology diminishes the lag between longwall production and roadway development and effectively prevents coal and gas outburst,which offers the prospect of broad application. | Shen Chunming Lin Baiquan Meng Fanwei Zhang Qizhi Zhai Cheng | 2012 | International Journal of Mining Science and Technology2012，22，4： | 10 |
| 18 | Influence of pulse magneto-oscillation on the efficiency of grain refiner显示文摘 | Tian-Yu Liu Jie Sun Cheng Sheng Qi-Xin Wang Yun-Hu Zhang Li-Juan Li Hong-Gang Zhong Qi-Jie Zhai | 2017 | Advances in Manufacturing2017，5，2： | 10 |
| 19 | Study on 'fracturing-sealing' integration technology based on high-energy gas fracturing in single seam with high gas and low air permeability显示文摘To improve the gas extraction efficiency of single seam with high gas and low air permeability,we developed the'fracturing-sealing'integration technology,and carried out the engineering experiment in the3305 Tunliu mine.In the experiment,coal seams can achieve the aim of antireflection effect through the following process:First,project main cracks with the high energy pulse jet.Second,break the coal body by delaying the propellant blasting.Next,destroy the dense structure of the hard coal body,and form loose slit rings around the holes.Finally,seal the boreholes with the'strong-weak-strong'pressurized sealing technology.The results are as follows:The average concentration of gas extraction increases from8.3%to 39.5%.The average discharge of gas extraction increases from 0.02 to 0.10 m^3/min.The tunneling speeds up from 49.5 to 130 m/month.And the permeability of coal seams improves nearly tenfold.Under the same conditions,the technology is much more efficient in depressurization and antireflection than common methods.In other words,it will provide a more effective way for the gas extraction of single seam with high gas and low air permeability. | Zhang Chao Lin Baiquan Zhou Yan Zhai Cheng Zhu Chuanjie | 2013 | International Journal of Mining Science and Technology2013，23，6： | 10 |
| 20 | Pulsating hydraulic fracturing technology in low permeability coal seams显示文摘Based on the difficult situation of gas drainage in a single coal bed of high gas content and low permeability, we investigate the technology of pulsating hydraulic pressure relief, the process of crank plunger movement and the mechanism of pulsating pressure formation using theoretical research, mathematical modeling and field testing. We analyze the effect of pulsating pressure on the formation and growth of fractures in coal by using the pulsating hydraulic theory in hydraulics. The research results show that the amplitude of fluctuating pressure tends to increase in the case where the exit is blocked, caused by pulsating pressure reflection and frictional resistance superposition, and it contributes to the growth of fractures in coal. The crack initiation pressure of pulsating hydraulic fracturing is 8 MPa, which is half than that of normal hydraulic fracturing; the pulsating hydraulic fracturing influence radius reaches 8 m.The total amount of gas extraction is increased by 3.6 times, and reaches 50 L/min at the highest point.The extraction flow increases greatly, and is 4 times larger than that of drilling without fracturing and 1.2times larger than that of normal hydraulic fracturing. The technology provides a technical measure for gas drainage of high gas content and low permeability in the single coal bed. | Wang Wenchao Li Xianzhong Lin Baiquan Zhai Cheng | 2015 | International Journal of Mining Science and Technology2015，25，4： | 9 |
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