|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Bone Morphogenetic Protein (BMP) signaling in development and human diseases显示文摘Bone Morphogenetic Proteins(BMPs)are a group of signaling molecules that belongs to the Transforming Growth Factor-b(TGF-b)superfamily of proteins.Initially discovered for their ability to induce bone formation,BMPs are now known to play crucial roles in all organ systems.BMPs are important in embryogenesis and development,and also in maintenance of adult tissue homeostasis.Mouse knockout models of various components of the BMP signaling pathway result in embryonic lethality or marked defects,highlighting the essential functions of BMPs.In this review,we first outline the basic aspects of BMP signaling and then focus on genetically manipulated mouse knockout models that have helped elucidate the role of BMPs in development.A significant portion of this review is devoted to the prominent human pathologies associated with dysregulated BMP signaling. | Richard N.Wang Jordan Green Zhongliang Wang Youlin Deng Min Qiao Michael Peabody Qian Zhang Jixing Ye Zhengjian Yan Sahitya Denduluri Olumuyiwa Idowu Melissa Li Christine Shen Alan Hu Rex C.Haydon Richard Kang James Mok Michael J.Lee Hue L.Luu Lewis L.Shi | 2014 | Genes & Diseases2014，1，1： | 47 |
| 2 | Immobilization of TiO_2 nanoparticles on activated carbon fiber and its photodegradation performance for organic pollutants显示文摘The immobilization of titanium dioxide (TiO 2 ) on activated carbon fiber (ACF), (TiO 2 /ACF), was accomplished by sol–gel-adsorption method followed by calcination at temperatures varying from 300 to 600 °C in an argon atmosphere. The material properties were determined by scanning electron microscope (SEM), X-ray diffraction (XRD) and nitrogen adsorption. The photodegradation behavior of TiO 2 /ACF was investigated in aqueous solutions using phenol and methyl orange (MO) as target pollutants. The effects of calcination temperature, photocatalyst dosage, initial solution pH and radiation time on the degradation of organic pollutants were studied. It was found that organic pollutants could be removed rapidly from water by the TiO 2 /ACF photocatalyst and the sample calcined at 500 °C exhibited the highest removal efficiency. Kinetics analysis showed that the photocatalytic degradation reaction can be described by a first-order rate equation. In addition, the possibility of cyclic usage of the photocatalyst was also confirmed. Moreover, TiO 2 is tightly bound to ACF and can be easily handled and recovered from water. It can therefore be potentially applied for the treatment of water contaminated by organic pollutants. | Shuhua Yao Jinyang Li Zhongliang Shi | 2010 | Particuology2010，8，3： | 22 |
| 3 | Insulin-like growth factor(IGF)signaling in tumorigenesis and the development of cancer drug resistance显示文摘One of the greatest obstacles to current cancer treatment efforts is the development of drug resistance by tumors.Despite recent advances in diagnostic practices and surgical interventions,many neoplasms demonstrate poor response to adjuvant or neoadjuvant radiation and chemotherapy.As a result,the prognosis for many patients afflicted with these aggressive cancers remains bleak.The insulin-like growth factor(IGF)signaling axis has been shown to play critical role in the development and progression of various tumors.Many basic science and translational studies have shown that IGF pathway modulators can have promising effects when used to treat various malignancies.There also exists a substantial body of recent evidence implicating IGF signaling dysregulation in the dwindling response of tumors to current standard-of-care therapy.By better understanding both the IGF-dependent and-independent mechanisms by which pathway members can influence drug sensitivity,we can eventually aim to use modulators of IGF signaling to augment the effects of current therapy.This review summarizes and synthesizes numerous recent investigations looking at the role of the IGF pathway in drug resistance.We offer a brief overview of IGF signaling and its general role in neoplasia,and then delve into detail about the many types of human cancer that have been shown to have IGF pathway involvement in resistance and/or sensitization to therapy.Ultimately,our hope is that such a compilation of evidence will compel investigators to carry out much needed studies looking at combination treatment with IGF signaling modulators to overcome current therapy resistance. | Sahitya K.Denduluri Olumuyiwa Idowu Zhongliang Wang Zhan Liao Zhengjian Yan Maryam K.Mohammed Jixing Ye Qiang Wei Jing Wang Lianggong Zhao Hue H.Luu | 2015 | Genes & Diseases2015，2，1： | 21 |
| 4 | UKF-based multi-sensor passive tracking with active assistance显示文摘A new synergy tracking method of infrared and ra dar is presented. To improve tracking accuracy, the unscented Kalman filter (UKF ), which has better nonlinear approximation ability, is adopted. In addition, to reduce the possibility of radar being locked-on by adverse electronic support measure (ESM), radar is under the intermittent-working state. After radar is tu rned off, the possible target position is estimated by a set of time polynomials , which is constructed based on the sufficient observations done before radar is turned off, the estimated values from time polynomials are compared with the cu rrent observation values from infrared to determine the time when radar is turne d on. Simulation results show the method has a good tracking accuracy and effect ively reduces the possibility of radar being locked-on by adverse ESM. | Li Anping Jing Zhongliang Hu Shiqiang | 2006 | Journal of Systems Engineering and Electronics2006，17，2： | 20 |
| 5 | TGF-β promotes invasion and metastasis of gastric cancer cells by increasing fascinl expression via ERK and JNK signal pathways显示文摘 | Hua Fu Zhongliang Hu Jifang Wen Kuansong Wang Ying Liu | 2009 | Acta Biochimica et Biophysica Sinica2009，41，8： | 19 |
| 6 | Inter-annual variations in vegetation and their response to climatic factors in the upper catchments of the Yellow River from 2000 to 2010显示文摘在黄河的上面的集水在有气候因素的植被和他们的关联理解变化,中国,从 2000 ~ 2010 的规范的差别植被索引(NDVI ) 时间系列数据基于 MOD13Q1 产品被收集。变化, Theil 参议员中部的趋势分析和 Mann-Kendall 测试的系数被联合调查轻快特征和植被的趋势特征。气候数据集合然后被用来在植被和气候变化分析在变化之间的关联。以时间的变化,在这个学习区域的植被从 2000 ~ 2010 稍微改善了,尽管轻快特征比在 20062010 在 20002005 是更大的。以空间变化,相对稳定并且有一个显著地增加的趋势的植被说明学习区域的最大的部分。它的空间分发高度与高度被相关,它在这个区域从大约 2000 ~ 3000 m 。显示出一个显著地减少的趋势的高度波动的植被和植被主要与水力发出的电力开发在水库附近并且在河的活动范围被散布。有一个相对稳定、显著地减少的趋势的植被和有高度波动和显著地增加的趋势的植被广泛地被驱散。关于到气候变化的植被的反应,大约 2030% 植被与气候的因素有重要关联,在大多数区域的关联是积极的:有降水的区域作为关键影响因素占超过 10% 区域;有温度的区域作为关键影响因素占不到 10% 区域;并且有降水和温度的区域作为一起影响因素的钥匙占大约 5% 全部的区域。超过 70% 植被与气候的因素有不足道的关联。 | CAO Ran JIANG Weiguo YUAN Lihua WANG Wenjie LV Zhongliang CHEN Zheng | 2014 | Journal of Geographical Sciences2014，24，6： | 19 |
| 7 | Constraints on the age of the Tuchengzi Formation by LA-ICP-MS dating in northern Hebei-western Liaoning, China显示文摘Accurately determining the age of the Tuchengzi Formation has direct influence on confirming the boundary between the Jurassic and the Cretaceous systems in northern Hebei-western Liaoning, and on related geological problems in China. However, the Tuchengzi Formation mainly consists of sedi-mentary rocks, with a poor fossil record and especially lack of index fossils. The Tuchengzi Formation is also lack of the type of volcanic rocks that can provide an isotopic age. Therefore, the age of the Tuchengzi Formation has been uncertain. Based on our systematic dating of the tuff interbedded in the Tuchengzi Formation of Chengde and Jinlingsi-Yangshan basins in northern Hebei-western Liaoning, combined with the dating results of previous researchers, here we suggest that the age range of the Tuchengzi Formation in northern Hebei-western Liaoning is from 147 Ma to 136 Ma. It implied that the Tuchengzi Formation was mainly formed in the Early Cretaceous. | ZHANG Hong WEI ZhongLiang LIU XiaoMing LI Dong | 2009 | Science China Earth Sciences2009，52，4： | 18 |
| 8 | Effect of N and P addition on soil organic C potential mineralization in forest soils in South China显示文摘Atmospheric nitrogen deposition is at a high level in some forests of South China. The effects of addition of exogenous N and P on soil organic carbon mineralization were studied to address: (1) if the atmospheric N deposition promotes soil C storage through decreasing mineralization; (2) if the soil available P is a limitation to organic carbon mineralization. Soils (0-10 cm) was sampled from monsoon evergreen broad-leaved forest (MEBF), coniferous and broad-leaved mixed forest (CBMF), and Pinus massoniana forest (PMF) in Dinghushan Biosphere Reserve (located in Guangdong Province, China). The soils were incubated at 25°C for 45 weeks, with addition of N (NH4NO3 solution) or P (KH2PO4 solution). CO2-C emission and the inorganic N (NH4+-N and NO3?-N) of the soils were determined during the incubation. The results showed that CO2-C emission decreased with the N addition. The addition of P led to a short-term sharp increase in CO2 emission after P application, and the responses of CO2-C evolution to P addition in the later period of incubation related to forest types. Strong P inhibition to CO2 emission occurred in both PMF and CBMF soils in the later incubation. The two-pool kinetic model was fitted well to the data for C turnover in this experiment. The model analysis demonstrated that the addition of N and P changed the distribution of soil organic C between the labile and recalcitrant pool, as well as their mineralization rates. In our experiment, soil pH can not completely explain the negative effect of N addition on CO2-C emission. The changes of soil inorganic N during incubation seemed to support the hypothesis that the polymerization of added nitrogen with soil organic compound by abiotic reactions during incubation made the added nitrogen retard the soil organic carbon mineralization. We conclude that atmospheric N deposition contributes to soil C accretion in the three subtropical forest ecosystems, however, the shortage of soil available P in CBMF and PMF may also retard soil organic C mineralization. | OUYANG, Xuejun ZHOU, Guoyi HUANG, Zhongliang ZHOU, Cunyu LI, Jiong SHI, Junhui ZHANG, Deqiang | 2008 | Journal of Environmental Sciences2008，20，9： | 17 |
| 9 | LA-ICP-MS Zircon U-Pb Geochronology of Quartz Porphyry from the Niutougou Gold Deposit in Songxian County,Henan Province显示文摘The Niutougou gold deposit,located in the center of the Xiong'ershan gold district,western Henan Province,is a large gold deposit with many quartz porphyries found in the area.Based on the field geological investigation of quartz porphyry of Niutougou gold deposit and by using the cathodoluminescence(CL) images analysis and in situ LA-ICP-MS U-Pb isotope dating method of zircons,the inner structure,trace element compositions and U-Pb age of the zircons separated from quartz porphyry were analyzed and determined.Cathodoluminescence(CL) images of zircons show clear magmatic zonations.Trace element analyses of zircons reveal that all zircons show high concentrations of Th,U,and HREE,and the REE patterns of depletion in LREE,with a positive Ce anomaly.Zircon LA-ICP-MS U-Pb dating results show that the quartz porphyry in the Niutougou gold deposit was formed at 159.71±0.99 Ma(about 160 Ma),belonging to the product of magmatic activity in late Middle Jurassic.Combined with the geological characteristics of the Niutougou gold deposit,the formation age of the quartz porphyry and the analysis of the formation age of the granite body exposed in the Niutougou gold deposit,the study suggests that the metallogenic epoch of the Niutougou gold deposit may be Yanshanian in age. | WANG Zhongliang GONG Qingjie SUN Xiang WU Fafu WANG Weixing | 2012 | Acta Geologica Sinica(English Edition)2012，86，2： | 17 |
| 10 | Experimental investigation of the influence of electric field on frost layer growth under natural convection condition显示文摘直接电流(DC ) 的影响一个冷垂直盘子上的霜的厚度和团上的电场被调查。生长有或没有电场的存在被拿,并且结果的霜层的相片证明电走在霜厚度上有强烈影响。霜厚度和霜质量上的冷板温度和周围的温度的影响也与电场在自然传送对流条件下面被调查。试验性的结果证明冷板温度在霜层厚度,而是它对霜质量的影响上有很强壮的效果是次要的;对霜团的影响或周围的温度在霜厚度上是比那更明显的。 | ZHANG Xinhua, LIU Zhongliang, WANG Jieteng, GOU Yujun, MENG Sheng and MA Chongfang Key Laboratory of Enhanced Heat Transfer and Energy Conservation, Ministry of Education Key Laboratory of Heat Transfer and Energy Conversion, Beijing Education Commission, Beijing University of Technology, Beijing 100022, China | 2006 | Progress in Natural Science:Materials International2006，16，4： | 16 |
| 11 | A numerical study of rock burst development and strain energy release显示文摘We consider rock burst to be a dynamic disaster similar to earthquakes,rapid land sliding,or coal mine gas dynamic disasters.Multi-scale mechanical principles imply the same mechanism of damage evolution proceeds the catastrophe.Damage may occur at various scales from a meso-scopic scale to a macroscopic,or engineering scale.Rock burst is a catastrophe at the scale of the engineering structure,such as a tunnel cross section or the work face of a long wall mine.It results from dynamic fracture of the structure where microscopic damage nucleates,expands,and finally propagates into a macroscopic sized fracture band.Rock burst must,therefore,undergo a relatively long development,or gestation,time before its final appearance.In this paper,a study of rock burst within a deeply buried tunnel by numerical methods is described.The results show that during rock burst gestation the distributed microscopic damage in the rock surrounding the tunnel localizes,intersects,and then evolves into a set of concentrated ''V'' shaped damage bands.These concentrated damage bands propagate in the direction of maximum shear as shearing slide bands take shape.Rock burst happens within the wedge separated by the shear bands from the native tunnel rock.An analysis of the wedge fracture shows that the unloading effects result in rock burst and rapid release of the strain energy.The implications for rock burst prediction in tunnels are that:(1) rock burst develops in the upper arch corners of in the tunnel cross section prior to developing in other zones,so good attention must be paid there;(2) all monitoring,prevention,and treatment of rock burst should be done during the gestation phase;(3) the shear bands contain abundant information concerning the physics and mechanics of the process and they are the foundation of physical and mechanical monitoring of acoustic emission,micro seismic events,stress,and the like.Thus a special study of the shearing mechanism is required. | Wang Li Lu ZhongLiang Gao Qian | 2012 | International Journal of Mining Science and Technology2012，22，5： | 16 |
| 12 | The versatile functions of Sox9 in development,stem cells,and human diseases显示文摘The transcription factor Sox9 was first discovered in patients with campomelic dysplasia,a haploinsufficiency disorder with skeletal deformities caused by dysregulation of Sox9 expression during chondrogenesis.Since then,its role as a cell fate determiner during embryonic development has been well characterized;Sox9 expression differentiates cells derived from all three germ layers into a large variety of specialized tissues and organs.However,recent data has shown that ectoderm-and endoderm-derived tissues continue to express Sox9 in mature organs and stem cell pools,suggesting its role in cell maintenance and specification during adult life.The versatility of Sox9 may be explained by a combination of posttranscriptional modifications,binding partners,and the tissue type in which it is expressed.Considering its importance during both development and adult life,it follows that dysregulation of Sox9 has been implicated in various congenital and acquired diseases,including fibrosis and cancer.This review provides a summary of the various roles of Sox9 in cell fate specification,stem cell biology,and related human diseases.Ultimately,understanding the mechanisms that regulate Sox9 will be crucial for developing effective therapies to treat disease caused by stem cell dysregulation or even reverse organ damage. | Alice Jo Sahitya Denduluri Bosi Zhang Zhongliang Wang Liangjun Yin Zhengjian Yan Richard Kang Lewis L.Shi James Mok Michael J.Lee Rex C.Haydon | 2014 | Genes & Diseases2014，1，2： | 16 |
| 13 | Response of grain yield to plant density and nitrogen rate in spring maize hybrids released from 1970 to 2010 in Northeast China显示文摘The objective of this study was to identify the response of grain yield to plant density and nitrogen rate in spring maize hybrids released from 1970 to 2010 and grown extensively in Northeast China.Twenty-one hybrids were grown for 2 years in Northeast China at densities of 30,000,52,500,75,000,and 97,500 plants ha^(-1)and N application levels of 0,150,300,and 450 kg N ha^(-1).Irrespective of density or nitrogen application rate,grain yields both per plant and per unit area were significantly higher for newer than older hybrids.As plant density increased from 30,000 to 97,500 plant ha^(-1),yield per plant of 1970 s,1980 s,1990 s,and 2000 s hybrids decreased by 50%,45%,46%,and 52%,respectively.The response of grain yield per unit area to plant density was curvilinear.The estimated optimum plant densities were about 58,000,49,000,65,000,and 65,000 plants ha^(-1)for hybrids released in the 1970 s,1980s,1990 s,and 2000 s,respectively.The theoretical optimum densities for the hybrids released from the 1970 s to the 2000 s increased by 1750 plants ha^(-1)decade^(-1).Nitrogen fertilization significantly increased grain yields per plant and per unit area for all hybrids.The theoretical optimum N application rates for high yield for hybrids released in the 1970 s and 1980 s were about 280 and 360 kg ha^(-1),and the hybrids from the 1990 s and 2000 s showed highest yield at 330 kg ha^(-1)N.No significant difference in the grain yields of 2000 s hybrids between the N levels of 150 to 450 kg ha^(-1)was found.Significant yield gains per plant and per unit area were found,with average increases of 17.9 g plant^(-1)decade^(-1)and936 kg ha^(-1)decade^(-1)over the period 1970–2010,respectively.Yield gains were attributed mainly to increased yield per plant,contributed by increases in kernel number per ear and1000-kernel weight.The rates of lodging and barren plants of newer hybrids were significantly lower than those of older ones,especially at high plant density. | Chunrong Qian Yang Yu Xiujie Gong Yubo Jiang Yang Zhao Zhongliang Yang Yubo Hao Liang Li Zhenwei Song Weijian Zhang | 2016 | The Crop Journal2016，4，6： | 15 |
| 14 | World-class Xincheng gold deposit: An example from the giant Jiaodong gold province显示文摘The Jiaodong gold deposits are currently the most important gold resources(with Au reserves of>4000 t) in China,and the leading gold-producing country globally(with Au production of ~428 t in2013).Jiaodong is also considered as perhaps the only world-class to giant gold accumulation on the planet where relatively young gold ores(ca.130-120 Ma) were deposited in rocks that are 2 Ga older.The Xincheng world-class high-grade gold deposit,with a proven reserve of >200 t gold,is one of the largest deposits in the giant gold province of the Jiaodong Peninsula.It is located in the northwestern part of the jiaobei Uplift,and hosted by ca.132-123 Ma Xincheng quartz monzonites and monzogranites.Ore zones are structurally controlled by the NE-trending and NW-dipping Jiaojia Fault and subsidiary faults,and are mainly restricted to the footwall of the fault.The dominant disseminated- and stockworkstyle ores are associated with strong sericitization,silicification,sulfidation and K-feldspathization,and minor carbonate wallrock alteration halos.The four mineralization stages are pyrite-quartz-sericite(stage 1),quartz-pyrite(stage 2),quartz-polysulfide(stage 3) and quartz-carbonate(stage 4).Gold occurs dominantly as electrum,with lesser amounts of sulfide-hosted native gold and rare native silver and argentite,normally associated with pyrite,chalcopyrite,galena and sphalerite:the latter with proven resources of about 105 t Ag,713 t Cu,and 5100 t S.There are three types of ore-related fluid inclusions:type 1 aqueous-carbonate(H_2O-CO_2),type 2aqueous(liquid H_2O+vapor H_2O),and type 3 CO_2(liquid CO_2 and vapor CO_2) inclusions.Homogenization temperatures range from 221 to 304℃ for type 1 inclusions,with salinities of 2.4-13.3 wt.%NaCl eq.,and bulk densities of 0.858-1.022 g/cm^3.The δ^(34)S_(CDT) values of hydrothermal sulfides are 4.3-10.6‰and δ^(18)O values of hydrothermal quartz have a median value of 13.0‰.δD values of fluid inclusions in hydrothermal quartz have a median value of-75‰.Calculated δ^(18)Owater has a median value of 5.2‰.The timing of gold mineralization at the Xincheng gold deposit is younger than 123±1 Ma,and likely between 120.9 and 119.9 Ma.A minerals system genetic model for the probable epizonal orogenic Xincheng deposit suggests an initial medium temperature,CO_2-rich,and low salinity H_2O-CO_2 deeply sourced metamorphic ore fluid associated with dehydration and decarbonization of subducting Paleo-Pacific lithosphere.The Jiaojia Fault constrained the migration of ore-forming fluids and metals at the brittle-ductile transition.Fluid immiscibility,caused by episodic pressure drops,led to significant high-grade gold deposition in the giant Xincheng gold deposit. | Liqiang Yang Jun Deng Ruipeng Guo Lin'nan Guo Zhongliang Wang Binghan Chen XudongWang | 2016 | Geoscience Frontiers2016，7，3： | 14 |
| 15 | Water regime-nitrogen fertilizer incorporation interaction:Field study on methane and nitrous oxide emissions from a rice agroecosystem in Harbin, China显示文摘Water regime and nitrogen(N) fertilizer are two important factors impacting greenhouse gases(GHG) emission from paddy field, whereas their effects have not been well studied in cold region. In this study, we conducted a two-year field experiment to study the impacts of water regime and N fertilizer on rice yields and GHG emissions in Harbin, China, a cold region located in high latitudes. Our results showed that intermittent irrigation significantly decreased methane(CH_4) emission compared with continuous flooding, however,the decrement was far lower than the global average level. The N_2O emissions were very small when flooded but peaked at the beginning of the disappearance of floodwater. The N fertilizer treatments increased CH_4 emissions at low level(75 kg N/ha). But both CH_4 and N_2O emissions were uninfluenced at the levels of 150 kg N/ha and 225 kg N/ha. Rice yields increased under intermittent irrigation and were highest at the level of 150 kg N/ha. From our results, we recommended that the intermittent irrigation and 150 kg N/ha as the ideal water regime-nitrogen fertilizer incorporation for this area to achieve low GHG emissions without impacting rice yields. | Wenjun Dong Jia Guo Lijun Xu Zhifeng Song Jun Zhang Ao Tang Xijuan Zhang Chunxu Leng Youhong Liu Lianmin Wang Lizhi Wang Yang Yu Zhongliang Yang Yilei Yu Ying Meng Yongcai Lai | 2018 | Journal of Environmental Sciences2018，30，2： | 12 |
| 16 | Principle and practice of coupling support of double yielding shell of soft rock roadway under high stress显示文摘In order to ensure the safety and stability of the soft rock roadway under high stress, based on the characteristics of the surrounding rock deformation and failure, this paper presented the support technology‘‘coupling support of double yielding shell'', then gave the design method of inner and outer shells and analyzed the principle and requirements of the support technology by taking the -850 m east belt roadway of Qujiang coal mine as the background. The field application results show that the support technology can control the soft rock roadway deformation better under high stress. The displacement between roadway sides was 851 mm, the displacement of the roof was 430 mm, and the displacement of the floor was 510 mm. | Li Chong Wang Zhongliang Liu Tao | 2014 | International Journal of Mining Science and Technology2014，24，4： | 10 |
| 17 | Deformation of freezing water droplets on a cold copper surface显示文摘Freezing processes of water and peanut oil droplets on a cold surface are investigated in this paper. We observed during our experiments that the base surface of a water droplet that is in direct contact with the cold surface keeps its original shape, but the other part of the droplet shows an obvious growth along the direction normal to the base surface. One small protrusion appears on the top of the water droplet at the end of the freezing process. The experimental observations also show that no obvious shape change happens during the freezing of peanut oil droplets. It is postulated that the effects of sur- face tension and volume dilatation resulted from liquid-to-solid phase change cause the shape change and protrusions formation. Based on this postulation, a physical and mathematical model is developed. The results of the model of a water droplet’s freezing process correspond with our experimental observations. The observed phenomenon that frost-growth speed on the protrusion is higher than that on the other part of the water droplet is also analyzed. | WANG Jieteng LIU Zhongliang GOU Yujun ZHANG Xinhua CHENG Shuiyuan | 2006 | Science China(Technological Sciences)2006，49，5： | 9 |
| 18 | Near-perfect fidelity polarization-encoded multilayer optical data storage based on aligned gold nanorods显示文摘Encoding information in light polarization is of great importance in facilitating optical data storage(ODS)for information security and data storage capacity escalation.However,despite recent advances in nanophotonic techniques vastly en-hancing the feasibility of applying polarization channels,the data fidelity in reconstructed bits has been constrained by severe crosstalks occurring between varied polarization angles during data recording and reading process,which gravely hindered the utilization of this technique in practice.In this paper,we demonstrate an ultra-low crosstalk polarization-en-coding multilayer ODS technique for high-fidelity data recording and retrieving by utilizing a nanofibre-based nanocom-posite film involving highly aligned gold nanorods(GNRs).With parallelizing the gold nanorods in the recording medium,the information carrier configuration minimizes miswriting and misreading possibilities for information input and output,respectively,compared with its randomly self-assembled counterparts.The enhanced data accuracy has significantly im-proved the bit recall fidelity that is quantified by a correlation coefficient higher than 0.99.It is anticipated that the demon-strated technique can facilitate the development of multiplexing ODS for a greener future. | Linwei Zhu Yaoyu Cao Qiuqun Chen Xu Ouyang Yi Xu Zhongliang Hu Jianrong Qiu Xiangping Li | 2021 | Opto-Electronic Advances2021，4，11： | 9 |
| 19 | Highly expressed BMP9/GDF2 in postnatal mouse liver and lungs may account for its pleiotropic effects on stem cell differentiation,angiogenesis,tumor growth and metabolism显示文摘Bone morphogenetic protein 9(BMP9)(or GDF2)was originally identified from fetal mouse liver cDNA libraries.Emerging evidence indicates BMP9 exerts diverse and pleiotropic functions during postnatal development and in maintaining tissue homeostasis.However,the expression landscape of BMP9 signaling during development and/or in adult tissues remains to be analyzed.Here,we conducted a comprehensive analysis of the expression landscape of BMP9 and its signaling mediators in postnatal mice.By analyzing mouse ENCODE transcriptome datasets we found Bmp9 was highly expressed in the liver and detectable in embryonic brain,adult lungs and adult placenta.We next conducted a comprehensive qPCR analysis of RNAs isolated from major mouse tissues/organs at various ages.We found that Bmp9 was highly expressed in the liver and lung tissues of young adult mice,but decreased in older mice.Interestingly,Bmp9 was only expressed at low to modest levels in developing bones.BMP9-associated TGFβ/BMPR type I receptor Alk1 was highly expressed in the adult lungs.Furthermore,the feedback inhibitor Smads Smad6 and Smad7 were widely expressed in mouse postnatal tissues.However,the BMP signaling antagonist noggin was highly expressed in fat and heart in the older age groups,as well as in kidney,liver and lungs in a biphasic fashion.Thus,our findings indicate that the circulating BMP9 produced in liver and lungs may account for its pleiotropic effects on postnatal tissues/organs although possible roles of BMP9 signaling in liver and lungs remain to be fully understood. | Wei Liu Zhongliang Deng Zongyue Zeng Jiaming Fan Yixiao Feng Xi Wang Daigui Cao Bo Zhang Lijuan Yang Bin Liu Mikhail Pakvasa William Wagstaff Xiaoxing Wu Huaxiu Luo Jing Zhang Meng Zhang Fang He Yukun Mao Huiming Ding Yongtao Zhang Changchun Niu Rex C.Haydon Hue H.Luu Jennifer Moriatis Wolf Michael J.Lee Wei Huang Tong-Chuan He Yulong Zou | 2020 | Genes & Diseases2020，7，2： | 9 |
| 20 | Stress wave propagation in supporting bolts:A test for bolt support quality显示文摘A test method for the non-destructive determination of bolt length,anchoring length,and bolt body force is described.This addresses the problems of low accuracy,limited number of data,and untimely warning signs encountered with existing test methods.Numerical simulations of the bolt,resin,and rock system show that the length accuracy when using the velocity wave is lower than when using the acceleration wave.It is accepted practice to use the acceleration wave for length tests because of improved signal to noise ratios of the waveforms.Laboratory and in situ underground tests showed that the precision of the measurements meets field requirements.Using this method the anchor properties of each single bolt and,thus,the safety of the entire roadway support may be evaluated. | Wu Rui Xu Jinhai Li Chong Zhou Baojing Ma Qianqian Wang Zhongliang | 2012 | International Journal of Mining Science and Technology2012，22，4： | 9 |
您所在的机构暂未开通此部分的功能，请联系管理员