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| 1 | Electropharmacological properties of telmisartan in blocking hKvl.5 and HERG potassium channels expressed on Xenopus laevis oocytes^1显示文摘瞄准:这研究的目的是调查 telmisartan 的禁止的行动,一种选择血管收缩素 II 类型 1 个受体对手,在 hKv1.5 和人的 ether-a-go-go-related 上,基因(HERG ) 隧道在 Xenopus laevis 卵母细胞上表示了。方法:hKv1.5 和 HERG 隧道在 Xenopus laevis 卵母细胞上被表示并且用 2-microelectrode 电压学习了夹钳技术。结果:在 hKv1.5 隧道, telmisartan 生产了电压依赖者和集中依赖者抑制;封锁的功效在山峰和 1.5 s 结束脉搏电流是不同的,它是 7.75%± 2 .39%( 一半最大的抑制集中[IC 50]=2.25 ± 0.97 μmol/L ) 并且在 1 μmol/L telmisartan 的 52.64%± 3 .77%(IC 50=0.82 ± 0.39 μmol/L ) 分别地。同时, telmisartan 加速了在里面隧道的激活。然而, telmisartan 为 HERG 隧道(IC 50=24.35 ± 5.06 μmol/L ) 展出了一种低亲密关系;封锁是电压依赖者和集中依赖者。Telmisartan 优先地堵住了开状态的 HERG 隧道。释放的慢时间常数被加速(n=6, P<0.05 ) ,它与“ foot-in-the-door ”不一致效果。结论:Telmisartan 堵住在治疗学的剂量的血浆集中层次包含开、使 \O 失去活性的状态的 hKv1.5 钾隧道;而 HERG 隧道的封锁仅仅在在上发生,血浆集中在开、靠近状态的隧道治疗学的剂量并且优先地铺平。 | Dan-na TU Yu-hua LIAO An-ruo ZOU Yi-mei DU Qi RUN Xian-pei WANG Lu LI | 2008 | Acta Pharmacologica Sinica2008，29，8： | 10 |
| 2 | Relationship Between Coleoptile Length and Drought Resistance and Their QTL Mapping in Rice显示文摘By using a set of recombinant inbred line(RIL)population involving in 195 lines derived from a cross of Zhenshan 97B (lowland variety)and IRAT109(upland variety),the correlation analysis between coleoptile length(CL)and drought resistance index (DRI)and their QTL identification were conducted.There existed a significantly positive relationship between CL and DRI with the correlation coefficient of 0.2206**under water stress conditions.Under normal and water stress conditions,a total of eleven and four QTLs for CL and DRI,respectively,were detected on chromosomes 1,2,4,5,6,7,9,11 and 12 by using a linkage map including 213 SSR markers,which explained 4.84%to 22.65%of phenotypic variance.Chromosomes 1 and 9 possessing the QTLs for DRI harbored simultaneously QTLs for CL,and qCL9 shared the same chromosome location with qDRI9(RM160-RM215).Comparing the QTLs related to drought resistance in other studies,QTLs for CL and DRI were located in the same or adjacent marker interval as those related to root traits,such as number,dry weight,depth,and length of root.Moreover,sixteen and three pairs of epistatic loci for CL and DRI were found,which accounted for 56.17%and 11.93%of the total variation in CL and DRI,respectively. | HU Song-ping YANG Hua ZOU Gui-hua LIU Hong-yan LIU Guo-lan MEI Han-wei CAI Run LI Ming-shou LUO Li-jun | 2007 | Rice science2007，14，1： | 4 |
| 3 | Comparison of linear and nonlinear analysis in estimating the Thomas model parameters for methylene blue adsorption onto natural zeolite in fixed-bed eolumn显示文摘 | HAN Run Ping WANG Yi ZOU Wei Hua | 2007 | J Hazard Mater2007，145，12： | 1 |
| 4 | Near-/mid-field effect of color mixing for single phosphor-converted light-emitting diode package 显示文摘 | HU Run YU Shan ZOU Yong ZHENG Hai WANG Fei LIU Sheng LUO Xiao-bing | 2013 | IEEE Photonics Technology Letters2013，25，3： | 1 |
| 5 | Nitric oxide-mediated immunosuppressive effect of Human amniotic membrane-derived mesenchymal stem cells on the viability and migration of microglia显示文摘 | Ke Yan Run Zhang Lei Chen Fanfan Chen Yi Liu Lingmei Peng Haitao Sun Weiyi Huang Chengmei Sun Bingke Lv Feng Li Yingqian Cai Yanping Tang Yuxi Zou Mouxuan Du Lingsha Qin Hengzhu Zhang Xiaodan Jiang | 2014 | Brain Research2014，，： | 1 |
| 6 | Highly textural lamellar mesostructured magnesium hydroxide via a cathodic electrodeposition process 显示文摘 | ZOU Guanglong LIU Run CHEN Weixiang | 2007 | Mater Lett2007，61，10： | 1 |
| 7 | Additive manufacturing of sodalite monolith for continuous heavy metal removal from water sources显示文摘Herein,we present a simple strategy for preparing monolithic sodalite adsorbents via sequential additive manufacturing and post-treatments.In detail,the method includes(i)3D printing of cylindrical monoliths using clay as the base material;(ii)thermal activation of the 3D-printed clay monoliths by calcination(to produce reactive alumina and silica species and enable mechanical stabilization);(iii)conversion of the activated clay monoliths to hierarchical porous sodalite monoliths via hydrothermal alkaline treatment.Parametric studies on the effect of calcination temperature,alkaline concentration and hydrothermal treatment time on the property of the resulting materials(such as phase composition and morphology)at different stages of preparation was conducted.Under the optimal conditions(i.e.,calcination temperature of 850℃,NaOH concentration of 3.3 mol·L^(-1),reaction temperature of 150℃,and reaction time of 6 h),a high-quality pure sodalite monolith was obtained,which possesses a relatively high BET surface area(58 m^(2)·g^(-1))and hierarchically micro-meso-macroporous structure.In the proposed application of continuous removal of heavy metals(chromium ion as the model)from wastewater,the developed 3D-printed sodalite monolith showed excellent Cr^(3+)removal performance and fast kinetics(~98%removal efficiency within 25 cycles),which outperformed the packed bed using sodalite pellets(made by extrusion). | Hengyu Shen Run Zou Yangtao Zhou Xing Guo Yanan Guan Duo Na Jinsong Zhang Xiaolei Fan Yilai Jiao | 2022 | Chinese Journal of Chemical Engineering2022，35，2： | 1 |
| 8 | Seasonal pattern of re- production of Hizikia fusiforme (Sargassaceae, Phaeo- phyta) from Nanao Island, Shantou, China显示文摘 | Zou D H Gao K S Run Z X | 2006 | J App Phyeol2006，18，： | 1 |
| 9 | Seasonal pattern of reproduction of Hizikia fusiforme (Sargassaceae, Phaeophyta) from Nanao Island, Shantou, China显示文摘 | Zou D H Gao K S Run Z X | 2006 | J Appl Phycol2006，18，2： | 1 |
| 10 | Study on the Reaction of α-Thiobenzoylthioformylmorpholine显示文摘The reactions of α - thiobenzoylthioformylmorpholine and compounds bearing amino group, such as diamine, aminoguanidine, semicarbazide and phenylacetylene have been explored. | Run Sheng ZENG Jian Ping ZOU Ai Feng WANG Zhong ELU(Department of Chemistry, Suzhou University, Suzhou 215006) | 1997 | Chinese Chemical Letters1997，8，11： | 0 |
| 11 | Advances in nuclear detection and readout techniques显示文摘“A Craftsman Must Sharpen His Tools to Do His Job,”said Confucius.Nuclear detection and readout techniques are the foundation of particle physics,nuclear physics,and particle astrophysics to reveal the nature of the universe.Also,they are being increasingly used in other disciplines like nuclear power generation,life sciences,environmental sciences,medical sciences,etc.The article reviews the short history,recent development,and trend of nuclear detection and readout techniques,covering Semiconductor Detector,Gaseous Detector,Scintillation Detector,Cherenkov Detector,Transition Radiation Detector,and Readout Techniques.By explaining the principle and using examples,we hope to help the interested reader underst and this research field and bring exciting information to the community. | Rui He Xiao‑Yang Niu Yi Wang Hong‑Wei Liang Hong‑Bang Liu Ye Tian Hong‑Lin Zhang Chao‑Jie Zou Zhi‑Yi Liu Yun‑Long Zhang Hai‑Bo Yang Ju Huang Hong‑Kai Wang Wei‑Jia Han Bei Cao Gang Chen Cong Dai Li‑Min Duan Rui‑Rui Fan Fang‑Fa Fu Jian‑Hua Guo Dong Han Wei Jiang Xian‑Qin Li Xin Li Zhuo‑Dai Li Yu‑Tie Liang Shun Liao De‑Xu Lin Cheng‑Ming Liu Guo‑Rui Liu Jun‑Tao Liu Ze Long Meng‑Chen Niu Hao Qiu Hu Ran Xiang‑Ming Sun Bo‑Tan Wang Jia Wang Jin‑Xiang Wang Qi‑Lin Wang Yong‑Sheng Wang Xiao‑Chuan Xia Hao‑Qing Xie He‑Run Yang Hong Yin Hong Yuan Chun‑Hui Zhang Rui‑Guang Zhao Ran Zheng Cheng‑Xin Zhao | 2023 | Nuclear Science and Techniques2023，34，12： | 0 |
| 12 | Chemical recycling of polyolefins:a closed-loop cycle of waste to olefins显示文摘The unsuitable disposal of plastic wastes has caused serious environmental pollution,and finding a green manner to address this problem has aroused wide concern.Plastic wastes,especially polyolefin wastes,are rich in carbon and hydrogen,and chemical recycling shows distinct advantages in their conversion into olefins and realizes a closed-loop cycling of plastic wastes.Plastic wastes should be labeled before disposal.The necessity for,and methods of,pretreatment are introduced in this paper and the whole recycling process of polyolefin wastes is also summarized.As the core technology pyrolysis,including thermal,catalytic and solvolysis processes,is introduced in detail due to its potential for future development.We also briefly describe the feasible strategies of pyrolytic oil refining and life cycle assessment of the chemical recycling process.In addition,suggestions and perspectives concerning the industrial improvement of polyolefin chemical recycling are proposed. | Liang Zou Run Xu Hui Wang Zhiqiang Wang Yuhan Sun Mingfeng Li | 2023 | National Science Review2023，10，9： | 0 |
| 13 | Cytotoxic sesquiterpene aryl esters from Armillaria gallica 012m显示文摘Objective:To study the chemical constituents of the EtOAc extract of Armillaria gallica 012m.Methods:The chemical constituents of the EtOAc extract of A.gallica 012m were isolated and purified by various column chromatography and their structures were elucidated on the basis of the 1D and 2D NMR spectroscopic and HRESIMS data.Cytotoxicity of all isolates against A549,HCT-116,M231 and W256 human tumor cells was determined by the MTT method.Results:A new sesquiterpene aryl ester,armimelleolide C(1),and eight known ones including armillarivin(2),melleolide F(3),6'-chloromelleolide F(4),melleolide(5),melleolide K(6),melledonol(7),13-hydroxydihydromelleolide(8),and armillane(9),were isolated from the EtOAc extract of A.gallica 012m.All isolates showed potential cytotoxic activities against at least one of the human cancer cell lines with IC_(50) values ranging from(3.17±0.54)to(17.57±0.47)μmol/L.Compound 1 showed significant inhibitory activity against M231 with an IC_(50) value of(7.54±0.24)μmol/L compared with paclitaxel as the positive control.Compounds 2,3,and 7,9 showed obvious inhibitory activity against HCT-116 and were better than that of the positive control.Conclusion:The chemical constituents including a new sesquiterpene aryl ester armimelleolide C(1)from the EtOAc extract of A.gallica 012m have a variety of structures and potential antitumor activities. | Yanping Li Shuizhu Lou Run Yang Ling Zhang Qiuping Zou Shanzhai Shang Lu Gao Weiguang Wang | 2023 | Chinese Herbal Medicines2023，15，2： | 0 |
| 14 | Projection-based High-dimensional Sign Test显示文摘This article is concerned with the high-dimensional location testing problem.For highdimensional settings,traditional multivariate-sign-based tests perform poorly or become infeasible since their Type I error rates are far away from nominal levels.Several modifications have been proposed to address this challenging issue and shown to perform well.However,most of modified sign-based tests abandon all the correlation information,and this results in power loss in certain cases.We propose a projection weighted sign test to utilize the correlation information.Under mild conditions,we derive the optimal direction and weights with which the proposed projection test possesses asymptotically and locally best power under alternatives.Benefiting from using the sample-splitting idea for estimating the optimal direction,the proposed test is able to retain type-I error rates pretty well with asymptotic distributions,while it can be also highly competitive in terms of robustness.Its advantage relative to existing methods is demonstrated in numerical simulations and a real data example. | Hui CHEN Chang Liang ZOU Run Ze LI | 2022 | Acta Mathematica Sinica,English Series2022，38，4： | 0 |
| 15 | Neonatal Staphylococcal Scalded Skin Syndrome:A Case Report显示文摘Objective:To summarize the clinical features,diagnosis,and treatment of neonatal staphylococcal scalded skin syndrome(SSSS).Methods:The clinical data with SSSS was analyzed,and the related literature was reviewed.Results:The acute onset of the disease was characterized by generalized erythema,epidermis exfoliation,skin non-touch,radial chapping around the mouth,and positive Nissl sign.The culture of binocular secretions and neck exudates showed Staphylococcus aureus and was diagnosed as SSSS.According to the results of drug sensitivity of secretions and exudates,vancomycin was selected for anti-infective treatment,and skincare and symptomatic support were given simultaneously.The child was cured and discharged after ten days of treatment.Conclusion:SSSS belongs to neonatal acute and critical illness.Improving etiological examination and timely targeted anti-infective treatment is the key to correct diagnosis and recovery. | Yuan-Xia Zou Jia-Yu Zhang Xiao-Xiu Ye Hui Zhou Run Li Gui-Ping Li | 2021 | TMR Integrative Nursing2021，5，3： | 0 |
| 16 | An FPGA‑based trigger system for CSHINE显示文摘A trigger system of the general function was designed using the commercial module of CAEN V2495 for heavy-ion nuclear reaction experiments at Fermi energies.The system was applied and verified on the compact spectrometer for heavy IoN experiment(CSHINE).Based on the field-programmable logic gate array technology of the command register access and remote computer control operation,trigger functions can be flexibly configured according to experimental physical goals.Using the trigger system on CSHINE,we conducted a beam experiment at 25 MeV/u^(86)Kr+^(124)Sn on the Radioactive Ion Beam Line 1 in Lanzhou,China.The online results demonstrated that the trigger system worked normally and correctly.This system can be extended to other experiments as well. | Dong Guo Yu‑Hao Qin Sheng Xiao Zhi Qin Yi‑Jie Wang Fen‑Hai Guan Xin‑Yue Diao Bo‑Yuan Zhang Yao‑Peng Zhang Da‑Wei Si Shi‑Wei Xu Xiang‑Lun Wei He‑Run Yang Peng Ma Tian‑Li Qiu Hai‑Chuan Zou Li‑Min Duan Zhi‑Gang Xiao | 2022 | Nuclear Science and Techniques2022，33，12： | 0 |
| 17 | Effects of cosolvents on CO_(2) displacement of shale oil and carbon storage显示文摘Molecular dynamics method was used to establish composite wall/inorganic nanopores of three pore sizes, three shale oil systems, five CO_(2)-cosolvent systems, and pure CO_(2) system. The process of CO_(2)-cosolvent displacement of crude oil in shale nanopores and carbon storage was simulated and the influencing factors of displacement and storage were analyzed. It is shown that the attraction of the quartz wall to shale oil increases with the degree of hydroxylation. The higher the degree of quartz hydroxylation, the more difficult it is to extract the polar components of shale oil. Nanopore size also has a great impact on shale oil displacement efficiency. The larger the pore size, the higher the shale oil displacement efficiency. The closer the cosolvent molecules are to the polarity of the shale oil, the higher the mutual solubility of CO_(2) and shale oil. The more the non-polar components of shale oil, the lower the mutual solubility of CO_(2) and shale oil with highly polar cosolvent. Ethyl acetate is more effective in stripping relatively high polar shale oil, while dimethyl ether is more effective in stripping relatively low polar shale oil. Kerogen is highly adsorptive, especially to CO_(2). The CO_(2) inside the kerogen is not easy to diffuse and leak, thus allowing for a stable carbon storage. The highest CO_(2) storage rate is observed when dimethyl ether is used as a cosolvent, and the best storage stability is observed when ethyl acetate is used as a cosolvent. | ZHANG Yifan WANG Lu ZOU Rui ZOU Run MENG Zhan HUANG Liang LIU Yisheng LEI Hao | 2023 | Petroleum Exploration and Development2023，50，6： | 0 |
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