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您的检索式：作者名="ZUO Fengli"
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| 1 | Determination of the Observation Area for Metallographic Microstructure of GH4033 Superalloy in a Uniaxially Thermo-Mechanical Compression Experiment显示文摘Based on two-dimensional(2D) rigid-plastic finite element(FE) method, the optimum observation area for metallographic microstructure and the influence of the height–diameter ratio on which were analyzed for the cylindrical samples with the diameter of 8 mm and different heights from 8 to 16 mm in nonuniform compressive experiments. It is shown that the representative metallographic observation area relevant to the applied deformation condition is located at about 0.835 of the radius from the center of the sample to the solder joint between the sample and the thermocouples. At the same time, the microstructure in that area is more appropriate as the height of the sample is 12 mm. The related parameters of GH4033 superalloy were adopted in the FE analysis, and the validity of this analysis was verified by the compressive experiments. | Fengli Sui Yue Zuo Jun Zhao Baoguo Ma | 2014 | Acta Metallurgica Sinica(English Letters)2014，27，3： | 4 |
| 2 | ParaUel difference schemes for heat conduction equations 显示文摘 | YUAN Guangwei ZUO Fengli | 2003 | Intern J Computer Math2003，80，8： | 1 |
| 3 | Parallel Differences Schemes for Heat Conduction Equation显示文摘 | Guangwei Yuan~ Fengli Zuo | 2003 | In- ternational Journal of Computer Mathematics2003，80，8： | 1 |
| 4 | Aberrant NF-κB activation in odontoblasts orchestrates inflammatory matrix degradation and mineral resorption显示文摘Inflammation-associated proteinase functions are key determinants of inflammatory stromal tissues deconstruction.As a specialized inflammatory pathological process,dental internal resorption(IR)includes both soft and hard tissues deconstruction within the dentin-pulp complex,which has been one of the main reasons for inflammatory tooth loss.Mechanisms of inflammatory matrix degradation and tissue resorption in IR are largely unclear.In this study,we used a combination of Cre-loxP reporter,flow cytometry,cell transplantation,and enzyme activities assay to mechanistically investigate the role of regenerative cells,odontoblasts(ODs),in inflammatory mineral resorption and matrices degradation.We report that inflamed ODs have strong capabilities of matrix degradation and tissue resorption.Traditionally,ODs are regarded as hard-tissue regenerative cells;however,our data unexpectedly present ODs as a crucial population that participates in IR-associated tissue deconstruction.Specifically,we uncovered that nuclear factor-kappa b(NF-κB)signaling orchestrated Tumor necrosis factorα(TNF-α)-induced matrix metalloproteinases(Mmps)and Cathepsin K(Ctsk)functions in ODs to enhance matrix degradation and tissue resorption.Furthermore,TNF-αincreases Rankl/Opg ratio in ODs via NF-κB signaling by impairing Opg expression but increasing Rankl level,which utterly makes ODs cell line 17IIA11(A11)become Trap^(+) and Ctsk^(+) multinucleated cells to perform resorptive actions.Blocking of NF-κB signaling significantly rescues matrix degradation and resorptive functions of inflamed ODs via repressing vital inflammatory proteinases Mmps and Ctsk.Utterly,via utilizing NF-κB specific small molecule inhibitors we satisfactorily attenuated inflammatory ODs-associated human dental IR in vivo.Our data reveal the underlying mechanisms of inflammatory matrix degradation and resorption via proteinase activities in IR-related pathological conditions. | Fanyuan Yu Fengli Huo Feifei Li Yanqin Zuo Chenglin Wang Ling Ye | 2022 | International Journal of Oral Science2022，14，1： | 1 |
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