| 1 | Issues in the Reconstruction of Gene Order Evolution显示文摘As genomes evolve over hundreds of millions years, the chromosomes become rearranged, with segments of some chromosomes inverted, while other chromosomes reciprocally exchange chunks from their ends. These rearrangements lead to the scrambling of the elements of one genome with respect to another descended from a common ancestor. Multidisciplinary work undertakes to mathematically model these processes and to develop statistical analyses and mathematical algorithms to understand the scrambling in the chromosomes of two or more related genomes. A major focus is the reconstruction of the gene order of the ancestral genomes. | David Sankoff 郑春芳 Adriana Muoz 杨振宇 Zaky Adam Robert Warren 蔡维仁 祝谦 | 2010 | Journal of Computer Science & Technology2010，25，1： | 0 |
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