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| 1 | High doses of α-galactosylceramide potentiate experimental autoimmune encephalomyelitis by directly enhancing Th17 response显示文摘伪 - Galactosylceramide (伪 - GC ) 广泛地被知道激活不变的自然漂亮 T (iNKT ) 压制髓磷脂的房间抗原特定的 Th1 回答,保护易受影响的老鼠免于试验性的自体免疫的脑脊髓炎(EAE ) 。这里,我们表明那高加重,而非改善的伪 - GC 开 EAE 的意外发现。当与高剂量的伪 - GC 对待的 MOG35-55-specific T 房间被变成 na 时,类似的结果被观察 ? ve syngeneic 接受者老鼠。进一步的学习证明伪 - GC 的高剂量直接通过 STAT3 的 phosphorylation 和 NF-魏 B 的激活由 CD4+CD44+ 记忆 T 房间的激活提高 Th17 和 Th1 反应。不同于由伪 - GC 的低剂量的 iNKT 房间的激活,伪 - GC 的高剂量直接交往了, CD1d 在 T 房间上表示了并且激活 Th17 和 Th1 房间。而且,介绍抗原的房间(APC ) 主要表示 CD1d1,而 CD4+ T 房间快车 CD1d2 的多数。由 RNAi 的 CD1d1 或 CD1d2 基因表示击倒分别地防碍 iNKT 或 Th17/Th1 房间的激活。因此,伪 - GC 处理能改善或变得更坏由雇佣取决于剂量的 APC 或 Th17/Th1 房间的 EAE 使用了。 | Gaochao Qian Xia Qin Ying Qin Zang Baoxue Ge Taylor B Guo Bing Wan Lei Fang Jingwu Z Zhang | 2010 | Cell Research2010，20，4： | 3 |
| 2 | Bovine serum albumin loaded poly (lactide-co-glycolide) microspheres, the influence of polymer purity on particle charaeteristies显示文摘 | BITTNER B RONNEBERGER B ZANGE R etal | 1998 | J Microencapsul1998，15，4： | 1 |
| 3 | Unexpected effect of concomitantly administered cureumin on the pharmacokinetics of talinolol in healthy Chinese volunteers 显示文摘 | He Juan Terhaag B Zang Cong | 2007 | Eur J Clin Phar- macol2007，63，7： | 1 |
| 4 | New and improved approaches for shared-path protection in WDM mesh networks显示文摘 | OU C ZHANG J ZANG H SHASRABUDDHE L H MUKHERJEE B | 2004 | IEEE/OSA Journal of Lightwave Technology2004，22，5： | 1 |
| 5 | A novel 'targetconstituent knock-out' strategy coupled with TLC, UPLC-ELSD and microcalorimetry for preliminary screening of antibacterial constituents in Calculus bovis 显示文摘 | Kong W J Wang J B Zang Q C | 2011 | J Chromatogr B2011，879，30： | 1 |
| 6 | Zirconia-toughened Si3N4 bond- ing polycrystalline cubic boron nitride (PCBN') 显示文摘 | Zang J B Han W Wang M I | 2001 | Key Enqineering Materials2001，，： | 1 |
| 7 | Matrix metalloproteinase production by bone marrow mononuclear cells from normal individuals and patients with acute and chronic myeloid leukemia or myelodysplastic syndromes显示文摘 | Ries C Loher F Zang C B | 1999 | Clin Cancer Res1999，5，5： | 1 |
| 8 | Do abnormally high auditfees impair audit quality 显示文摘 | Choi J H Kim J B Zang Y | 2010 | Auditing : A Journal ofPractice and Theory2010，29，2： | 1 |
| 9 | Critical role for c-FLIPL on Fas resistance in colon carcinoma cell line HT-29显示文摘 | Zang F Sun B Zhao X | 2008 | Cell Biol Int2008，32，3： | 1 |
| 10 | Construetion of Fingerprinting and Genetic Diversity of Mulberry Cuhivars in China by ISSR Markers 显示文摘 | ZHAO W G MIAO X X ZANG B | 2006 | Aeta Genetica Siniea2006，33，9： | 1 |
| 11 | Research joint ventures and R&d Cartels显示文摘 | Kamien M I Muller B Zang I | 1992 | AER1992，62，5： | 1 |
| 12 | Artificial immune pattern recogni-tion for structure damage classification 显示文摘 | CHEN B ZANG C | 2009 | Computers & Structures2009，87，21： | 1 |
| 13 | The application of 120 -W high -per- formance system GreenLight laser vaporization of the prostate in high - risk patients显示文摘 | Tao W Xue B Zang Y | 2013 | Lasers Med Sci2013，28，4： | 1 |
| 14 | Asymmetric mating interactions drive widespread invasion and displacement in a whitefly显示文摘 | Liu S S De Barro P J Xu J Luan J B Zang L S Ruan Y M Wan F H | | 0，，： | 1 |
| 15 | Plant regeneration of turf -type common bermudagrass (Cynoclon dactylon )via somatic em- bryogenesis from seed -derived callus显示文摘 | Zang Y X Hong S B Murugesan D J | 2006 | Hortic Environ Biotech2006，47，： | 1 |
| 16 | A novel “target constituent knock-out” strategy coupled with TLC, UPLC-ELSD and microcalorimetry for preliminary screening of antibacterial constituents in Calculus bovis显示文摘 | Kong W J Wang J B Zang Q C | 2011 | J Chromatogr B2011，879，30： | 1 |
| 17 | Construction of fingerprinting and genetic diversity of mulberry cuhivars in china by ISSR markers显示文摘 | ZHAO W G MIAO X X ZANG B | 2006 | Acta Gen Sin2006，33，9： | 1 |
| 18 | A review of routing and wavelength assignment approaches for wavelength- routed optical WDM networks 显示文摘 | ZANG H JUE J P MUKHERJEE B | 2000 | Optical Network Magazine2000，1，1： | 1 |
| 19 | Effect of coating on the microstructure and thermal conductivities of diamond-Cu composites pre- pared by powder metallurgy 显示文摘 | Ren S B Shen X Y Guo C Y Liu N Zang J B He X B Qu X H | 2011 | Composites Science and Technology2011，71，13： | 1 |
| 20 | Construction of fingerprinting and genetic diversity of mulberry cultivars in China by ISSR markers显示文摘 | Zhao W G Miao X X Zang B | 2006 | Acta Genet Sin2006，33，9： | 1 |
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