|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Deciphering the superior thermoelectric property of posttreatment-free PEDOT:PSS/IL hybrid by X-ray and neutron scattering characterization显示文摘In this work,a polymer and ionic liquid(IL)hybrid with superior thermoelectric performance is prepared via a system design of the chemical composition,molar ratio of the constituent molecules and manipulating the structure in solution and dried films.The solution-casted hybrid film,consisting of poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)and 1-ethyl-3-methylimidazolium tricyanomethanide(EMIM:TCM),shows the highest power factor of 175μW m^(−1) K^(−2) in the polymer hybrid prepared by a post-treatment-free method.With a set of complementary structure characterization methods,it is found that EMIM:TCM can induce the structure reorganization of PEDOT:PSS in solution from a core-shell model to a rod-like model,during which PEDOT partially separates from PSS that eases the conductive network formation.In addition,the oxidation level of PEDOT:PSS is reduced by adding EMIM:TCM.Based on which,the PEDOT:PSS/IL hybrid shows the best performance in optimizing the conductivity(1163 S cm^(−1))and Seebeck coefficient(38.8μV K^(−1))simultaneously. | Xin Li Ruike Zou Zhen Liu Jitendra Mata Ben Storer Yu Chen Weiheng Qi Zekun Zhou Peng Zhang | 2022 | npj Flexible Electronics2022，6，1： | 2 |
| 2 | A high-precision compensated CMOS bandgap voltage reference without resistors显示文摘 | Ming Xin Ma Yingqian Zhou Zekun | 2010 | IEEE Transactions on Circuit and System Ⅱ2010，57，10： | 1 |
| 3 | Amorphous carbon-linked TiO_(2)/carbon nanotube film composite with enhanced photocatalytic performance:The effect of interface contact and hydrophilicity显示文摘Carbon nanotube film(CNTF)can be used for photocatalysis and water treatment due to its porous structure,good stability and excellent electrical properties.In this work,TiO_(2)/amorphous carbon/carbon nanotube film(TCC)composite with uniform structure was prepared by a simple atomization spraying method.Rhodamine B(RhB)was used to test the photocatalytic activity of TCC.TCC composite exhibits good photocatalytic activity under ultraviolet light.In particular,the degradation efficiency of rhodamine B(RhB)by TCC sprayed with 9 layers of TiO_(2)(9 TCC)increased by 1.45 times than of TiO_(2) under ultraviolet light.The enhanced photocatalytic activity of TCC is attributed to the CNTF,which can broaden the light response range of TCC and improve the migration efficiency of electrons.The existence of amorphous carbon will promote these advances.Moreover,the better hydrophilic properties would enhance the catalytic performance happened on the solid-liquid interface.Finally,the photocatalytic mechanism and degradation intermediates of the TCC composite were proposed. | Zekun Xin Xiaodong Zhao Huiming Ji Tianyi Ma Hui Li Shuhui Zhong Zhurui Shen | 2021 | Chinese Chemical Letters2021，32，7： | 1 |
| 4 | Modification of alternative splicing in bovine somatic cell nuclear transfer embryos using engineered CRISPR-Cas13d显示文摘Animal cloning can be achieved by somatic cell nuclear transfer(SCNT),but the resulting live birth rate is relatively low.We previously improved the efficiency of bovine SCNT by exogenous melatonin treatment or by overexpression of lysine-specific demethylase 4D(KDM4D)and 4E(KDM4E).In this study,we revealed abundant alternative splicing(AS)transitions during fertilization and embryonic genome activation,and demonstrated abnormal AS in bovine SCNT embryos compared with in vitro fertilized embryos.We used the CRISPR-Cas13d RNA-targeting system to target cis-elements of ABI2 and ZNF106 pre-m RNA to modify AS,thus reducing the ratio of abnormal-isoform SCNT embryos by nearly 50%and achieving a high survival rate(11%–19%).These results indicate that this system may provide an efficient method for bovine cloning,while also paving the way for further improvements in the efficiency of SCNT. | Rui Cheng Xiaoman Zheng Yingmei Wang Xing Ma Xin Liu Wenjun Xu Mengyun Wang Yuanpeng Gao Xupeng Xing Chuan Zhou Hongzheng Sun Zekun Guo Fusheng Quan Jun Liu Song Hua Yongsheng Wang Yong Zhang Xu Liu | 2022 | Science China(Life Sciences)2022，65，11： | 1 |
| 5 | Tumor-microenvironment activated duplex genome-editing nanoprodrug for sensitized near-infrared titania phototherapy显示文摘Near-infrared(NIR)-light-triggered nanomedicine, including photodynamic therapy(PDT)and photothermal therapy(PTT), is growing an attractive approach for cancer therapy due to its high spatiotemporal controllability and minimal invasion, but the tumor eradication is limited by the intrinsic anti-stress response of tumor cells. Herein, we fabricate a tumor-microenvironment responsive CRISPR nanoplatform based on oxygen-deficient titania(TiO_(2-x)) for mild NIR-phototherapy. In tumor microenvironment, the overexpressed hyaluronidase(HAase) and glutathione(GSH) can readily destroy hyaluronic acid(HA) and disulfide bond and releases the Cas9/sgRNA from TiO_(2-x) to target the stress alleviating regulators, i.e., nuclear factor E2-related factor 2(NRF2) and heat shock protein 90a(HSP90a), thereby reducing the stress tolerance of tumor cells. Under subsequent NIR light illumination, the TiO_(2-x) demonstrates a higher anticancer effect both in vitro and in vivo. This strategy not only provides a promising modality to kills cancer cells in a minimal side-effects manner by interrupting anti-stress pathways but also proposes a general approach to achieve controllable gene editing in tumor region without unwanted genetic mutation in normal environments. | Zekun Li Yongchun Pan Shiyu Du Yayao Li Chao Chen Hongxiu Song Yueyao Wu Xiaowei Luan Qin Xu Xiaoxiang Guan Yujun Song Xin Han | 2022 | Acta Pharmaceutica Sinica B2022，12，11： | 0 |
| 6 | Discussion on wind factor influencing the distribution of biological soil crusts on surface of sand dunes显示文摘Biological soil crusts are widely distributed in arid and semi-arid regions,whose formation and development have an important impact on the restoration process of the desert ecosystem.In order to explore the relationship between surface airflow and development characteristics of biological soil crusts,we studied surface airflow pattern and development characteristics of biological soil crusts on the fixed dune profile through field observation.Results indicate that the speed of near-surface airflow is the lowest at the foot of windward slope and the highest at the crest,showing an increasing trend from the foot to the crest.At the leeward side,although near-surface airflow increases slightly at the lower part of the slope after an initial sudden decrease at upper part of the slope,its overall trend decreases from the crest.Wind velocity variation coefficient varied at different heights over each observation site.The thickness,shear strength of biological soil crusts and percentage of fine particles at crusts layer decreased from the slope foot to the upper part,showing that biological soil crusts are less developed in high wind speed areas and well developed in low wind speed areas.It can be seen that there is a close relationship between the distribution of biological soil crusts in different parts of the dunes and changes in airflow due to geomorphologic variation. | YongSheng Wu Hasi Erdun RuiPing Yin Xin Zhang Jie Ren Jian Wang XiuMin Tian ZeKun Li HengLu Miao | 2013 | Research in Cold and Arid Regions2013，5，6： | 0 |
| 7 | Optimal confrontation position selecting games model and its application to one-on-one air combat显示文摘In the air combat process,confrontation position is the critical factor to determine the confrontation situation,attack effect and escape probability of UAVs.Therefore,selecting the optimal confrontation position becomes the primary goal of maneuver decision-making.By taking the position as the UAV’s maneuver strategy,this paper constructs the optimal confrontation position selecting games(OCPSGs)model.In the OCPSGs model,the payoff function of each UAV is defined by the difference between the comprehensive advantages of both sides,and the strategy space of each UAV at every step is defined by its accessible space determined by the maneuverability.Then we design the limit approximation of mixed strategy Nash equilibrium(LAMSNQ)algorithm,which provides a method to determine the optimal probability distribution of positions in the strategy space.In the simulation phase,we assume the motions on three directions are independent and the strategy space is a cuboid to simplify the model.Several simulations are performed to verify the feasibility,effectiveness and stability of the algorithm. | Zekun Duan Genjiu Xu Xin Liu Jiayuan Ma Liying Wang | 2024 | Defence Technology(防务技术)2024，31，1： | 0 |
| 8 | Author correction to “Tumor-microenvironment activated duplex genome-editing nanoprodrug for sensitized near-infrared titania phototherapy” [Acta Pharm Sin B (2022) 4224-4234]显示文摘The authors regret that there is an error in the article Fig.5E due to the mistake of copying and pasting in the process of assembling figures and negligence in the proofreading.Although it does not affect the conclusion,it is an obvious error.The authors have now modified as below.The authors apologize for any inconvenience caused to the journal and readers. | Zekun Li Yongchun Pan Shiyu Du Yayao Li Chao Chen Hongxiu Song Yueyao Wu Xiaowei Luan Qin Xu Xiaoxiang Guan Yujun Song Xin Han | 2024 | Acta Pharmaceutica Sinica B2024，14，2： | 0 |
| 9 | A developed ant colony algorithm for cancer molecular subtype classification to reveal the predictive biomarker in the renal cell carcinoma显示文摘Background:Recently,researchers have been attracted in identifying the crucial genes related to cancer,which plays important role in cancer diagnosis and treatment.However,in performing the cancer molecular subtype classification task from cancer gene expression data,it is challenging to obtain those significant genes due to the high dimensionality and high noise of data.Moreover,the existing methods always suffer from some issues such as premature convergence.Methods:To address those problems,we propose a new ant colony optimization(ACO)algorithm called DACO to classify the cancer gene expression datasets,identifying the essential genes of different diseases.In DACO,first,we propose the initial pheromone concentration based on the weight ranking vector to accelerate the convergence speed;then,a dynamic pheromone volatility factor is designed to prevent the algorithm from getting stuck in the local optimal solution;finally,the pheromone update rule in the Ant Colony System is employed to update the pheromone globally and locally.To demonstrate the performance of the proposed algorithm in classification,different existing approaches are compared with the proposed algorithm on eight high-dimensional cancer gene expression datasets.Results:The experiment results show that the proposed algorithm performs better than other effective methods in terms of classification accuracy and the number of feature sets.It can be used to address the classification problem effectively.Moreover,a renal cell carcinoma dataset is employed to reveal the biological significance of the proposed algorithm from a number of biological analyses.Conclusion:The results demonstrate that CAPS may play a crucial role in the occurrence and development of renal clear cell carcinoma. | ZEKUN XIN YUDAN MA WEIQIANG SONG HAO GAO LIJUN DONG BAO ZHANG ZHILONG REN | 2023 | BIOCELL2023，47，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员