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您的检索式：作者名="Zeying Yan"
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| 1 | Chaotic laser synchronization and its application in optical fiber secure communication显示文摘In this paper, optical fiber chaotic secure communication is proposed by coupling chaotic laser synchronous system with optical fiber propagation channel. Feedback synchronous system of chaotic semiconductor lasers is presented and synchronous error and decoding formulae are demonstrated. Synchronization between two chaotic laser systems with distributed feedback semiconductor lasers at wavelength of 1.31 μm is simulatively achieved with almost zero synchronous error. Parameter mismatch, synchronous transient response and noise effect on the system are studied. Robustness of synchronization and anti-perturbation can increase by increasing the feedback coefficient of the system. Influence of group-velocity-dispersion and self-phase modulation of optical fiber on chaotic laser signal and synchronization are analyzed, and it is found that group-velocity-dispersion affects pulse shape, synchronization and decodin gand limits optical fiber propagation distances, and self-phase modulation does not affect pulse shape, while its product of nonlinear phase shift can affect synchronization and decoding, and restrict propagation distances of optical fiber chaotic communication system and hence the maximum optical power formula is educed. Injecting parameter modulation and amplitude modulation are numerically simulated in long-haul optical fiber secure communication systems. | YAN Senlin CHI Zeying CHEN Wenjian Schoof of Electronic Engineering and Photoelectronic Technology, Nanjing University of Science and Technology, Nanjing 210094, China | 2004 | Science in China(Series F)2004，47，3： | 10 |
| 2 | Efficacy and safety of combined decitabine and ruxolitinib in the treatment of chronic myelomonocytic leukemia显示文摘Objective The aim of the study was to evaluate the clinical efficacy of decitabine(DEC)combined with ruxolitinib(RUX)in the treatment of chronic myelomonocytic leukemia(CMML).Methods The clinical characteristics of 12 patients with CMML were analyzed retrospectively and subsequent target sequencing was performed to investigate the efficacy of the combined treatment with DEC and RUX and the molecular signatures therein.Results Among the 12 cases,clinical improvement was observed in all patients(100%),spleen reduction was observed in six patients(67%),and hematologic improvement was observed in four patients(33%).In the CMML-1 group,the overall response was 50%(3/6),one case achieved complete response,one achieved bone marrow remission,and one achieved hematological improvement.In the CMML-2 group,the overall response was 17%(1/6),one case achieved complete response,four showed disease progression(PD),and one exhibited no response.As expected,ASXL1 mutation was predictive for the outcome of CMML(hazard ratio of 2.97,95%confidence interval of 1.21–7.06;P=0.02).Conclusion The use of DEC combined with RUX in the treatment of CMML effectively improved the clinical response and quality of life,especially for CMML-1 patients.Ongoing clinical trials will further evaluate the safety and efficacy of this novel therapeutic approach. | Jiaming Li Sujiang Zhang Yubao Chen Zeying Yan Ying Wang Zhiyin Liu Haimin Sun Yu Chen | 2019 | Oncology and Translational Medicine2019，5，5： | 0 |
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