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| 1 | 门静脉高压并非肝细胞癌肝切除术的绝对禁忌证显示文摘在肝细胞癌(hepatocellular carcinoma,HCC)的各种临床分期系统中,Bruix J团队领衔的巴塞罗那肝癌临床分期标准(Barcelona Clinic Liver Cancer,BCLC)最受推崇,美国和欧洲肝病协会指南的制定亦基于该分期系统。BCLC认为门静脉高压显著增加HCC肝切除术后患者发生肝功能衰竭的风险, | Zhong JH Li H Xiao N Ye XP Ke Y Wang YY Ma L Chen J You XM Zhang ZY Lu SD Li LQ 钟鉴宏 齐鲁楠 | 2014 | 中国癌症防治杂志2014，6，4： | 18 |
| 2 | Pulmonary infection control window in treatment of severe respiratory failure of chronic obstructive pulmonary diseases: a prospective, randomized controlled, multi-centred study显示文摘Background Early withdraw from invasive mechanical ventilation (MV) followed by noninvasive MV is a new strategy for changing modes of treatment. This study was conducted to estimate the feasibility and the efficacy of early extubation and sequential noninvasive MV commenced at beginning of pulmonary infection control window in patients with exacerbated hypercapnic respiratory failure caused by chronic obstructive pulmonary diseases (COPD). Methods A prospective, randomized controlled study was conducted in eleven teaching hospitals' respiratory or medical intensive care units in China. Ninety intubated COPD patients with severe hypercapnic respiratory failure triggered by pulmonary infection (pneumonia or purulent bronchitis) were involved in the study. When the pulmonary infection had been controlled by antibiotics and comprehensive therapy, the 'pulmonary infection control window (PIC window)' has been reached. Each case was randomly assigned to study group (extubation and noninvasive MV via facial mask immediately) or control group (invasive MV was received continuously after PIC window by using conventional weaning technique).Results Study group (n=47) and control group (n=43) had similar clinical characteristics initially and at the time of PIC window. Compared with control group, study group had shorter duration of invasive MV [(6.4±4.4) days vs (11.3±6.2) days, P=0.000], lower rate of ventilator associated pneumonia (VAP) (3/47 vs 12/43, P=0.014), fewer days in ICU [(12±8) days vs (16±11) days, P=0.047] and lower hospital mortality (1/47 vs 7/43, P=0.025).Conclusions In COPD patients requiring intubation and invasive MV for hypercapnic respiratory failure, which is exacerbated by pulmonary infection, early extubation followed by noninvasive MV initiated at the start of PIC window may decrease significantly the duration of invasive MV, the risk of VAP and hospital mortality. | Wang, C Zhan, QY Cao, ZX Wei, LQ Cheng, ZZ Liu, S Zhang, JL Chen, RC Luo, Q Niu, SF Zhu, L Wu, DW Fang, BM Wu, TH Wang, CZ Liu, YN | 2005 | Chinese Medical Journal2005，，19： | 6 |
| 3 | Diterpenoid Alkaloids from Aconitum Pendulum显示文摘A new diterpenoid 12 -epiacetyldehydrolucidusculline (1) and a new norditerpenoid alkaloid 2-hydroxydeoxyaconitine (2) were isolated from the roots of Aconitum pendulum, together with eight known alkaloids aconitine (3), deoxyaconitine (4), 3-acetylaconitine (5), 12-epiacetyldehydronapelline (6), dehydrolucidusculline (7), dehydronapelline (8), 12 -epidehydrnapelline (9), and noeline (10). The structures of the new alkaloids (1-2) were determined on the basis of spectral method. | Zhang, SM Tan, LQ Ou, QY | 1997 | Chinese Chemical Letters1997，8，11： | 5 |
| 4 | An easy model for prediction of human renal clear cell carcinoma:curve fitting for three kidney tumors observed for over 10 years显示文摘 | Yao L Li XS Zhang L He ZS Zhou LQ | 2014 | Chinese Medical Journal2014，，4： | 3 |
| 5 | Regulation of gene expression with double-stranded phosphorothioate oligonucleotides显示文摘 | Bielinska A Shivdasani RA Zhang LQ | 1990 | Science1990，250，4983： | 1 |
| 6 | The effect of PF-127 on the rheology properties of monoolein/water mixtures 显示文摘 | Zhang J Zheng LQ Li GZ | 2006 | J Dispersion Sci Technol2006，27，： | 1 |
| 7 | MicroRNA-19b downregulatesinsulin 1 through targeting transcription factor NeuroDl 显示文摘 | Zhang ZW Zhang LQ Ding L | 2011 | FEBSLett2011，585，16： | 1 |
| 8 | Normal and hypertrophic scars: quantification and localization of messenger RNAs for type Ⅰ,Ⅲ and VI collagens显示文摘 | Zhang LQ Laato M Muona P | 1994 | Bri J Dermatol1994，130，4： | 1 |
| 9 | Pre-B-cell-colony-enhancing factor is critically involved in thrombin-induced lung endothelial cell barrier dysregulation显示文摘 | Ye SQ Zhang LQ Adyshev D | | 0，，： | 1 |
| 10 | Nicotinamide phosphoribosyltransferase in Human Diseases显示文摘 | Zhang LQ Hemth DP Ye SQ | 2011 | J Bioanal Biomed2011，3，： | 1 |
| 11 | Timing and dose regimens of mar- row mesenchymal stem cell transplantation affect the outcomes and neuroinflammatory response after ischemic stroke 显示文摘 | Wang LQ Lin ZZ Zhang HX | 2014 | CNS Neurosci Ther2014，20，4： | 1 |
| 12 | Adiponectin inhibits tissue factor expression and enhances tissue factor pathway inhibitor expression in human endothelial cells显示文摘 | Chen YJ Zhang LQ Wang GP | 2008 | Thromb Haemost2008，100，2： | 1 |
| 13 | Expression of a novel thermo- stable Cu, Zn - superexide dismutase from Chaetomium thermophilum in Pichia pastoris and its antioxidant properties 显示文摘 | Zhang LQ Guo FX Xian HQ | 2011 | Biotechnol Lett2011，33，6： | 1 |
| 14 | An Hphl polymorphism in the Eselectin gene is assoeia*ted with premature eoronary artery disease 显示文摘 | Zheng F Chevalier JA Zhang LQ | 2001 | Clin Genet2001，59，： | 1 |
| 15 | Comparison of later-al locking plate and antiglide plate for fixation of distal fibular fracturesin osteoporotic bone:a biomechanical study显示文摘 | Minihane KP Chulhyun Ahn CL Zhang LQ | 2006 | J Othop Trauma2006，8，： | 1 |
| 16 | Suture-button versus scre- w fixation of the syndesmosis: a biomechanical analysis显示文摘 | Klitzman R Zhao H Zhang LQ | 2010 | Foot Ankle Int2010，31，1： | 1 |
| 17 | 15th international symposium on the biology of the Actinomycetes; Shanghai 2009显示文摘 | Jones AL Zhang LX Bai LQ | 2010 | Antonie van Leeuwenhoek2010，98，： | 1 |
| 18 | The mechanism of mimecan transcription induced by glueocorticoid in pituitary corticotroph ceils 显示文摘 | Zhang XN Xue LQ Jiang H | 2012 | Molecular & Cellular Bochemstry2012，360，12： | 1 |
| 19 | Ionic liquid microemul-sions:A newmedium for electropolymerization显示文摘 | Dong B Zhang SH Zheng LQ | | 0，，07： | 1 |
| 20 | Normal and hyperstrophic scar:qualification and localization of messenger RNAs for type Ⅰ ,Ⅲ, Ⅵand collagens 显示文摘 | Loato M Munona P | 1994 | Br J Dermartol1994，130，： | 1 |
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