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| 1 | FIGL1 coordinates with dosage-sensitive BRCA2 in modulating meiotic recombination in maize显示文摘Meiotic crossover(CO)formation between homologous chromosomes ensures their subsequent proper segregation and generates genetic diversity among offspring.In maize,however,the mechanisms that modulate CO formation remain poorly characterized.Here,we found that both maize BREAST CANCER SUSCEPTIBILITY PROTEIN 2(BRCA2)and AAA-ATPase FIDGETIN-LIKE-1(FIGL1)act as positive factors of CO formation by controlling the assembly or/and stability of two conserved DNA recombinases RAD51 and DMC1 filaments.Our results revealed that Zm BRCA2 is not only involved in the repair of DNA double-stranded breaks(DSBs),but also regulates CO formation in a dosage-dependent manner.In addition,Zm FIGL1interacts with RAD51 and DMC1,and Zmfigl1 mutants had a significantly reduced number of RAD51/DMC1 foci and COs.Further,simultaneous loss of Zm FIGL1 and Zm BRCA2 abolished RAD51/DMC1foci and exacerbated meiotic defects compared with the single mutant Zmbrca2 or Zmfigl1.Together,our data demonstrate that Zm BRCA2 and Zm FIGL1 act coordinately to regulate the dynamics of RAD51/DMC1-dependent DSB repair to promote CO formation in maize.This conclusion is surprisingly different from the antagonistic roles of BRCA2and FIGL1 in Arabidopsis,implying that,although key factors that control CO formation are evolutionarily conserved,specific characteristics have been adopted in diverse plant species. | Ting Zhang Shuang‐Hui Zhao Yan Wang Yan He | 2023 | Journal of Integrative Plant Biology2023，65，9： | 0 |
| 2 | Survival and recurrence free benefits with different lymphadenectomy for resectable gastric cancer: A meta‐analysis显示文摘 | Lei Jiang Ke‐Hu Yang Quan‐Lin Guan Peng Zhao Yan Chen Jin‐Hui Tian | 2013 | J Surg Oncol2013，，8： | 3 |
| 3 | Brain‐derived neurotrophic factor stimulates proliferation and differentiation of neural stem cells, possibly by triggering the Wnt/β‐catenin signaling pathway显示文摘 | Bei‐Yu Chen Xi Wang Zhao‐Yan Wang Ya‐Zhou Wang Liang‐Wei Chen Zhuo‐Jing Luo | 2012 | J. Neurosci. Res2012，，1： | 2 |
| 4 | Survival and recurrence free benefits with different lymphadenectomy for resectable gastric cancer: A meta‐analysis显示文摘 | Lei Jiang Ke‐Hu Yang Quan‐Lin Guan Peng Zhao Yan Chen Jin‐Hui Tian | 2013 | J. Surg. Oncol2013，，： | 1 |
| 5 | Effect of a H ealth B elief M odel‐based nursing intervention on C hinese patients with moderate to severe chronic obstructive pulmonary disease: a randomised controlled trial显示文摘 | Ying Wang Xiao‐Ying Zang Jinbing Bai Su‐Yan Liu Yue Zhao Qing Zhang | 2014 | J Clin Nurs . 2014 (9-10)2014，，9： | 1 |
| 6 | Theoretical Prediction and Experimental Investigation on the Thermal and Mechanical Properties of Bulk β‐ Yb 2 Si 2 O 7显示文摘 | Yan‐Chun Zhou Cen Zhao Feng Wang Yin‐Jie Sun Li‐Ya Zheng Xiao‐Hui Wang | 2013 | J. Am. Ceram. Soc2013，，12： | 1 |
| 7 | Brain‐derived neurotrophic factor stimulates proliferation and differentiation of neural stem cells, possibly by triggering the Wnt/β‐catenin signaling pathway显示文摘 | Bei‐Yu Chen Xi Wang Zhao‐Yan Wang Ya‐Zhou Wang Liang‐Wei Chen Zhuo‐Jing Luo | 2012 | J Neurosci Res2012，，1： | 1 |
| 8 | EGR 1 is critical for gastrin‐dependent upregulation of anion exchanger 2 in gastric cancer cells显示文摘 | Ting Wang Lei Zhao Ye Yang Hua Tian Wen‐Hao Suo Min Yan Guo‐Hui Fu | 2012 | FEBS J2012，，1： | 1 |
| 9 | Nitrogen‐Containing Microporous Conjugated Polymers via Carbazole‐Based Oxidative Coupling Polymerization: Preparation, Porosity, and Gas Uptake显示文摘 | Qi Chen De‐Peng Liu Min Luo Li‐Juan Feng Yan‐Chao Zhao Bao‐Hang Han | 2014 | Small2014，，2： | 3 |
| 10 | Epidemiological survey and risk factor analysis of fatty liver disease of adult residents, B eijing, C hina显示文摘 | Jie Yan Wen Xie Wei‐ni Ou Hong Zhao Su‐yun Wang Jian‐hui Wang Qi Wang Yu‐ying Yang Xin Feng Jun Cheng | 2013 | J Gastroenterol Hepatol2013，，10： | 3 |
| 11 | Preparation of doxycycline‐imprinted magnetic microspheres by inverse‐emulsion suspension polymerization for magnetic dispersion extraction of tetracyclines from milk samples显示文摘 | Yun‐Kai Lv Chen‐Xi Zhao Pan Li Yan‐Dong He Zhong‐Rui Yang Han‐Wen Sun | 2013 | J Sep Science2013，，16： | 1 |
| 12 | Ischemic Postconditioning Diminishes Matrix Metalloproteinase 9 Expression and Attenuates Loss of the Extracellular Matrix Proteins in Rats Following Middle Cerebral Artery Occlusion and Reperfusion显示文摘 | Xiang‐Rong Liu Mei Luo Feng Yan Chen‐Cheng Zhang Si‐Jie Li Hai‐Ping Zhao Xun‐Ming Ji Yu‐Min Luo | 2012 | CNS Neurosci Ther2012，，10： | 1 |
| 13 | TNF ‐α Upregulates Fgl2 Expression in Rat Myocardial Ischemia/Reperfusion Injury显示文摘 | Peng Jia Jue Wang Li Wang Xin Chen Yu Chen Wen‐Zhu Li Rui Long Jian Chen Yan‐Wen Shu Kun Liu Zhao‐Hui Wang | 2013 | Microcirculation2013，，6： | 1 |
| 14 | Transplantation of H uman R etinal P igment E pithelium C ells in the T reatment for P arkinson D isease显示文摘 | Feng Yin Zeng‐Min Tian Shuang Liu Quan‐Jun Zhao Rui‐Min Wang Li Shen Jeffery Wieman Ying Yan | 2012 | CNS Neurosci Ther2012，，12： | 1 |
| 15 | Integrin β3 and its ligand regulate the expression of uPA through p38 MAPK in breast cancer显示文摘 | RUIWANG ZHAO‐QINGLI XUHAN BAI‐LINLI XIAO‐YIMI LI‐MEISUN MINSONG YAN‐CHUNHAN YANZHAO EN‐HUAWANG | 2010 | APMIS2010，，12： | 1 |
| 16 | The correlations between the expression of FGFR4 protein and clinicopathological parameters as well as prognosis of gastric cancer patients显示文摘 | Yan‐Wei Ye Xiefu Zhang Ye Zhou Jianghong Wu Chunlin Zhao Lin Yuan Guojun Wang Chunyan Du Chunmeng Wang Yingqiang Shi | 2012 | Oncol2012，，7： | 1 |
| 17 | Nitrous Oxide‐Oxygen Mixture During Burn Wound Dressing: A Double‐Blind Randomized Controlled Study显示文摘 | Yu‐Xiang Li Wen‐Jun Han Hong‐Tai Tang Yin‐Sheng Wu Lu Tang Jian‐Qiang Yu Yan‐Cang Li Zhao‐Fan Xia Ji‐Jun Zhao | 2013 | CNS Neurosci Ther2013，，： | 1 |
| 18 | Transplantation of Adipose‐Derived Stem Cells is Associated with Neural Differentiation and Functional Improvement in a Rat Model of Intracerebral Hemorrhage显示文摘 | Juan Chen Ying‐Xin Tang Yong‐Ming Liu Ji Chen Xiao‐Qing Hu Na Liu Shu‐Xin Wang Yu Zhang Wen‐Gao Zeng Hou‐Jie Ni Bin Zhao Yan‐Fang Chen Zhou‐Ping Tang | 2012 | CNS Neurosci Ther2012，，10： | 1 |
| 19 | Prevalence and extent of subclinical atherosclerosis in patients with psoriasis显示文摘 | K.‐H. Yiu C.‐K. Yeung C.‐T. Zhao J. C. Chan C.‐W. Siu S. Tam C.‐S. Wong G. H. Yan W. S. Yue P.‐L. Khong H. H. Chan H.‐F. Tse | 2012 | J Intern Med2012，，： | 1 |
| 20 | Downregulation and altered function of natural killer cells in hepatitis B virus patients treated with entecavir显示文摘 | Ping‐Wei Zhao Fei‐Yong Jia Yu‐Xing Shan Hui‐Fan Ji Jun‐Yan Feng Jun‐Qi Niu Desalegn A Ayana Yan‐Fang Jiang | 2013 | Clin Exp Pharmacol Physiol2013，，3： | 1 |
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