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| 1 | Nuclear Aurora kinase A switches m^(6)A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4显示文摘Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression,yet how this process is regulated by oncogenic signal remains largely unknown.Here,we unveil that non-canonical activation of nuclear AURKA promotes an oncogenic RNA splicing of tumor suppressor RBM4 directed by m^(6)A reader YTHDC1 in lung cancer.Nuclear translocation of AURKA is a prerequisite for RNA aberrant splicing,specifically triggering RBM4 splicing from the full isoform(RBM4-FL)to the short isoform(RBM4-S)in a kinase-independent manner. | SiSi Li YangFan Qi JiaChuan Yu YuChao Hao Bin He MengJuan Zhang ZhenWei Dai TongHui Jiang SuYi Li Fang Huang Ning Chen Jing Wang MengYing Yang DaPeng Liang Fan An JinYao Zhao WenJun Fan YuJia Pan ZiQian Deng YuanYuan Luo Tao Guo Fei Peng ZhiJie Hou ChunLi Wang FeiMeng Zheng LingZhi Xu Jie Xu QingPing Wen BiLian Jin Yang Wang Quentin Liu | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 4 |
| 2 | Route strategy of satellite network in GNSS based on topology evolution law显示文摘As each type of satellite network has different link features, its data transmission must be designed based on its link features to improve the efficiency of data transferring. The transmission of navigation integrated services information(NISI)in a global navigation satellite system(GNSS) with inter-satellite links(ISLs) is studied by taking the real situation of inter-satellite communication links into account. An on-demand computing and buffering centralized route strategy is proposed based on dynamic grouping and the topology evolution law of the GNSS network within which the satellite nodes are operated in the manner of dynamic grouping. Dynamic grouping is based on satellites spatial relationships and the group role of the satellite node changes by turns due to its spatial relationships. The route strategy provides significant advantages of high efficiency, low complexity, and flexible configuration, by which the established GNSS can possess the features and capabilities of feasible deployment, efficient transmission, convenient management, structural invulnerability and flexible expansion. | Xianqing Yi Zhenwei Hou Tao Zhong Yaohong Zhang Zhili Sun | 2014 | Journal of Systems Engineering and Electronics2014，25，4： | 2 |
| 3 | Analysis of Propagation and Polarization Characteristics of Electromagnetic Waves Through Nonuniform Magnetized Plasma Slab Using Propagator Matrix Method显示文摘 | Yin X Zhang Hou Zhao Zhenwei | 2013 | Progress in Electromagnetics Research2013，137，： | 1 |
| 4 | Study of Optical-electrical Conversion Interface for Power Supply’s of Ion Source显示文摘The quality of the beam produced by the ion source directly affects the superiority of the cyclotron beam.The 14MeV high dencity cyclotron uses an external multi-cusp ion source.Ion source power supply composes of filament power supply,arc voltage power supply,plasma power supply and puller power supply,which are | WANG Jingfeng HOU Shigang JIA Xianlu LI Pengzhan ZHANG He LIU Zhenwei | 2017 | Annual Report of China Institute of Atomic Energy2017，，1： | 0 |
| 5 | Design and Implementation of Safety Interlock System for Medical Small Cyclotron显示文摘Serial No.101room of the serial upgrade engineering Department 201is used as a test site for medical small cyclotrons and central area test benches.In the future,accelerator commissioning and beaming time will gradually increase.The original door interlock system was | LIU Zhenwei HOU Shigang LI Zhenguo GE Tao WANG Feng | 2017 | Annual Report of China Institute of Atomic Energy2017，，1： | 0 |
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