2篇
您的检索式：作者名="Zhixing Niu"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Hydrogel platform with tunable stiffness based on magnetic nanoparticles cross-linked GelMA for cartilage regeneration and its intrinsic biomechanism显示文摘Cartilage injury affects numerous individuals,but the efficient repair of damaged cartilage is still a problem in clinic.Hydrogel is a potent scaffold candidate for tissue regeneration,but it remains a big challenge to improve its mechanical property and figure out the interaction of chondrocytes and stiffness.Herein,a novel hybrid hydrogel with tunable stiffness was fabricated based on methacrylated gelatin(GelMA)and iron oxide nanoparticles(Fe_(2)O_(3))through chemical bonding.The stiffness of Fe_(2)O_(3)/GelMA hybrid hydrogel was controlled by adjusting the concentration of magnetic nanoparticles.The hydrogel platform with tunable stiffness modulated its cellular properties including cell morphology,microfilaments and Young’s modulus of chondrocytes.Interestingly,Fe_(2)O_(3)/GelMA hybrid hydrogel promoted oxidative phosphorylation of mitochondria and facilitated catabolism of lipids in chondrocytes.As a result,more ATP and metabolic materials generated for cellular physiological activities and organelle component replacements in hybrid hydrogel group compared to pure GelMA hydrogel.Furthermore,implantation of Fe_(2)O_(3)/GelMA hybrid hydrogel in the cartilage defect rat model verified its remodeling potential.This study provides a deep understanding of the bio-mechanism of Fe_(2)O_(3)/GelMA hybrid hydrogel interaction with chondrocytes and indicates the hydrogel platform for further application in tissue engineering. | Chenchen Zhou Chunli Wang Kang Xu Zhixing Niu Shujuan Zou Demao Zhang Zhiyong Qian Jinfeng Liao Jing Xie | 2023 | Bioactive Materials2023，，7： | 1 |
| 2 | The Impact of Key Factors on Flow Characteristics of 14 MW Reverse-Swirl Pulverized Coal Burner显示文摘Reverse-swirl(RS)burner which has been industrialized couples reverses jet and swirl flow for the stabilization of flame.Using Dantec multichannel constant-temperature anemometer,experiments on airflow characteristics were implemented on a 1:2 scaled burner model with different values in terms of reverse primary air(RPA)ratio and swirl inner secondary air(SISA)ratio.It was found that the shape of annular coupled recirculation zone(ACRZ)had stayed symmetrical all the time.The RPA ratio was the main factor that had an impact on the values of axial and RMS velocity as well as the radial velocity direction of ACRZ.Both RPA ratio and SISA ratio had a great impact on the area of ACRZ,relative reverse flow rate,mixing between SISA and outer secondary air(OSA)as well as swirling ability of the airflow.The area of ACRZ reached its peak when the RPA ratio was 11.92%or SISA ratio was 17.03%;however,when the RPA ratio and SISA ratio reached 14.86%and 28.41%respectively,the combination of RPA and SISA became relatively favorable;besides,ACRZ area,relative reverse flow and swirling ability became suitable and the mixing between SISA and OSA was relatively delayed.The research was of great practical and theoretical importance to the design and operation of RS burner. | JIA Nan NIU Fang LIU Pengzhong WANG Zhixing WANG Naiji ZHOU Jianming | 2021 | Journal of Thermal Science2021，30，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员