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| 1 | Long noncoding RNA UC.98 stabilizes atherosclerotic plaques by promoting the proliferation and adhesive capacity in murine aortic endothelial cells显示文摘Pathological studies have shown that the vulnerability of plaques affects outcomes in patients with atherosclerosis(AS),a chronic inflammatory disease and common cause of morbidity and mortality worldwide.Although emerging technologies have enabled early diagnosis of AS with high-risk vulnerable plaques,more accurate and noninvasive diagnostic methods are urgently required.To this end,molecules involved in genetic or epigenetic regulation of the vulnerability of atherosclerotic plaques have been extensively studied.Here,we evaluated long noncoding RNA(IncRNA)variability by microarray assay in murine aortic endothelial cells(MAECs)bearing wulnerable plaques and identified the novel functional IncRNA UC.98,whose expression pattern was associated with the vulnerability of atherosclerotic plaques.Consisient with this,clinical statistics comparing the peripheral blood specimens from sets of patients with AS with or without vulnerable plaques confirmed the linear relationship between the expression pattern of UC.98 and plaque instabilty.Moreover,MTT assays and western blot analysis showed that silencing of intrinsic UC 98 in MAECs not only suppressed cell proliferation but also decreased the expressions of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1,thereby inactivating the nuclear factorkB pathway.In conclusion,our results highlighted the pivotal role of UC.98 in regulating the vulnerability of plaques during AS progression and suggested that UC.98 may be a biomarker of the early diagnosis and prognosis of AS with vulnerable plaques and a potential therapeutic target for slowing AS progression. | Zixu Fan Ying Zhang Danrui Xiao Jianwei Ma Hua Liu Linghong Shen Min Zhang Ben He | 2020 | Acta Biochimica et Biophysica Sinica2020，52，2： | 3 |
| 2 | Ni3S2 nanorods growing directly on Ni foam for all-solid-state asymmetric supercapacitor and efficient overall water splitting显示文摘Transition metal compounds are attractive for their significant applications in supercapacitors and as non-noble metal catalysts for electrochemical water splitting.Herein,we develop Ni3 S2 nanorods growing directly on Ni foam,which act as multifunctional additive-free Ni3 S2@Ni electrode for supercapacitor and overall water splitting.Based on PVA-KOH gel electrolyte,the assembled all-solid-state Ni3 S2@Ni//AC asymmetric supercapacitor delivers a high areal energy density of 0.52 mWh cm^-2 at an areal power density of 9.02 MW cm^-2,and exhibits an excellent cycling stability with a capacitance retention ratio of 89%after 10000 GCD cycles at a current density of 30 mA cm^-2.For hydrogen evolution reaction and oxygen evolution reaction in 1 M KOH,Ni3 S2@Ni electrode achieves a benchmark of 10 mA cm^-2at overpotentials of 82 mV and 310 mV,respectively.Furthermore,the assembled Ni3 S2@Ni‖Ni3 S2@Ni electrolyzer for overall water splitting attains a current density of 10 mA cm^-2 at 1.61 V.The in-situ synthesis of Ni3 S2@Ni electrode enriches the applications of additive-free transition metal compounds in high-performance energy storage devices and efficient electrocatalysis. | Baoxin Wu Hao Qian Zhongwu Nie Zhongping Luo Zixu Wu Peng Liu Hao He Jianghong Wu Shuguang Chen Feifei Zhang | 2020 | Journal of Energy Chemistry2020，29，7： | 2 |
| 3 | Lithium-storage properties of SiO_(2)nanotubes@C using carbon nanotubes as templates显示文摘Silica-based anode material is the most concerned material at present,which has the advantages of good cycle stability,high theoretical specific capacity and abundant reserves.However,silica suffers from inherent low conductivity,severe volume expansion effect and low initial coulombic efficiency,which limits its application in lithium-ion batteries.Nanotubes structure can mitigate the volume expansion during lithiation/delithiation.In this article,silica nanotubes(SNTs)were prepared using carbon nanotubes(CNTs)as a template,and then the uniform carbon layer was coated on their surface by carbonization of citric acid.The hollow structure of nanotubes provides more sites for the insertion of Li+during lithiation and additional channels for Li+migration in the cycles,which improves the electrochemical performance.Conductivity can be enhanced by coating carbon layer.The specific capacity of the composite material is about 650 mAh g^(-1)at 0.1 A g^(-1)after 100 cycles.With a specific capacity of 400 mAh g^(-1)even at 1 A g^(-1)after 100 cycles.The silica-based material is a competitive anode material for lithium-ion batteries. | Zixu Shi Chaoyun Shi Huili Shi Binfang He Guoqiang Qin Ao Li Jing Zhu Jingbo Chen | 2023 | Particuology2023，，12： | 0 |
| 4 | Durable semi-crystalline interphase engineering to stabilize high voltage Ni-rich cathode in dilute ether electrolyte显示文摘Ethers are promising electrolyte solvents for secondary Li metal batteries because of their excellent reduction stability.However,their oxidation stability has been mostly relying on the high concentration approach,and limited progress has been made on building effective interphase to protect the cathode from the corrosion of the electrolyte.In this work,we construct a semi-crystalline interfacial layer on the surface of Li(Ni_(0.8)Co_(0.1)Mn_(0.1))O_(2)cathode that can achieve improved electrochemical stability in the highly corrosive chemical environment formed by the decomposition of ether molecules.Different from traditional brittle crystalline interphases,the optimized semi-crystalline layer with low modulus and high ionic conductivity can effectively relieve electrode strain and maintain the integrity of the interface layer.Due to this design,the continuous oxidation decomposition of ether-based electrolytes could be significantly suppressed and the battery shows outstanding cycling stability(84%capacity retention after 300 cycles).This article provides a solution to address the oxidation instability issue of ether-based electrolytes. | Zhuangzhuang Cui Shunqiang Chen Qingshun Nian Yecheng Li Yawei Chen Bing-Qing Xiong Zihong Wang Zixu He Shuhong Jiao Xiaodi Ren | 2023 | Journal of Energy Chemistry2023，，4： | 0 |
| 5 | Optimizing electronic structure of NiFe LDH with Mn-doping and Fe_(0.64)Ni_(0.36)alloy for alkaline water oxidation under industrial current density显示文摘Alkaline electrolyzers for water splitting under the industrial current densities are always burdened with huge energy consumption due to the high overpotential and poor stability of the anode nanocatalysts for oxygen evolution reaction(OER).Inspired by the interfacial charge transfer for enhancing the performance,a series of in-situ grown interfacial Mn-NiFe lactate dehydrogenase(LDH)was designed on the Fe_(0.64)Ni_(0.36)/NM(nickel mesh)alloy layer.The optimized Mn_(0.15)-NiFe LDH/Fe_(0.64)Ni_(0.36)/NM exhibited an ultralow overpotential of 295 mV to drive 500 mA·cm^(-2)and an incredible stability under large current density.The interfacial space and heteroatom doping synergistically triggered the electronic structure optimization to promote electron transfer and ensure the durability of the high-current reaction.Notably,the designed Mn_(0.15)-NiFe LDH/Fe_(0.64)Ni_(0.36)/NM as an anode in an integral alkaline electrolyzer exhibited a cell voltage of 1.78 V at 500 mA·cm^(-2) with a stability of 366 h.Density functional theory(DFT)calculations further demonstrated the synergistic effect of alloy layer introduction and Mn doping could accelerate electron transfer and stabilize the charged active center to activate the NiFe LDH and reduce the OER energy barrier.Our work offers new insights into developing efficient self-supported catalysts for high-current alkaline water oxidation. | Yang Qian Fan Zhang Lingshu Qiu Weiwei Han Zixu Zeng Lecheng Lei Yi He Ping Li Xingwang Zhang | 2023 | Nano Research2023，16，7： | 0 |
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