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| 1 | In vivo radiometric analysis of glucose uptake and distribution in mouse bone显示文摘Bone formation and remodeling occurs throughout life and requires the sustained activity of osteoblasts and osteoclasts,particularly during periods of rapid bone growth.Despite increasing evidence linking bone cell activity to global energy homeostasis,little is known about the relative energy requirements or substrate utilization of bone cells.In these studies,we measured the uptake and distribution of glucose in the skeleton in vivo using positron-emitting^(18)F-fluorodeoxyglucose([^(18)F]-FDG) and non-invasive,high-resolution positron emission tomography/computed tomography(PET/CT) imaging and ex vivo autoradiography.Assessment of [^(18)F]-FDG uptake demonstrated that relative to other tissues bone accumulated a significant fraction of the total dose of the glucose analog.Skeletal accumulation was greatest in young mice undergoing the rapid bone formation that characterizes early development.PET/CT imaging revealed that [^(18)F]-FDG uptake was greatest in the epiphyseal and metaphyseal regions of long bones,which accords with the increased osteoblast numbers and activity at this skeletal site.Insulin administration significantly increased skeletal accumulation of [^(18)F]-FDG,while uptake was reduced in mice lacking the insulin receptor specifically in osteoblasts or fed a high-fat diet.Our results indicated that the skeleton is a site of significant glucose uptake and that its consumption by bone cells is subject to regulation by insulin and disturbances in whole-body metabolism. | Meredith L Zoch Diane S Abou Thomas L Clemens Daniel LJ Thorek Ryan C Riddle | 2016 | Bone Research2016,4,1: | 9 |
| 2 | 高速水冷淬火过程中残余压应力的形成显示文摘据文献报道,快速水冷淬火可在试样表面形成残余压应力(RSs)从而显著提高其疲劳极限,这种技术被称为'强烈淬火'。德国热处理协会'淬火'技术委员会发起了一个旨在精确研究上述问题的研究项目。本文重点介绍马氏体相变对残余应力形成的影响。为了在圆柱试样表面得到残余压应力,需要确定合适的工艺窗口。在此窗口中,淬火冷却速度要求足够快,以致于在圆柱体内达到最大温度梯度之前,表面温度已经低于Ms。 | J Rath T Liibben F Hoffmann H-W Zoch 顾剑锋 | 2013 | 热处理2013,28,2: | 3 |
| 3 | Shortening the Duration of Heat Treatment in the Lower Bainitic Range显示文摘In many cases an isothermal treatment of throughhardening bearing grades in the lower bainitic range allows to adjust the mechanical properties of machine components to the later application, similar to those of martensitic hardening. The achieved microstructure contains only a negligible amount of retained austenite, so a dimensional change of components during application can be reduced. One disadvantage of the isothermal bainitic treatment in salt bath is that the duration of the treatment is much longer than that of the martensitic hardening and this causes higher costs. Therefore it would be desirable to be able to shorten the transformation duration in the lower bainitic range. The aim of the present work is to determine the parameters, by which the process could be greatly shortened in comparison with the conventional transformation process in the lower bainitic range. Therefore the bainitic transformation behavior of the steel 100 Cr6 (SAE 52100) and the relevant influence factors were investigated by means of dilatometry, in which the heat treatments were carried out with different process variants including pre-quenching or post-quenching. The amount of retained austenite in the microstructure and the hardness of the steel after the shortened heat treatments were measured. Finally the possibility to use these processes in industrial production is discussed. | H. Vetters H.-W. Zoch | 2004 | 材料热处理学报2004,25,5: | 2 |
| 4 | Deformation behavior of spray-formed hypereutectic Al–Si alloys显示文摘 | C. Cui A. Schulz J. Epp H. W. Zoch | 2010 | Journal of Materials Science2010,,10: | 2 |
| 5 | Spray forming of hypereuteetic A1-Si alloys显示文摘 | CUI C SCHULZ A SCHIMANSKI K ZOCH H W | 2009 | Journal of Materials Processing Technology2009,209,3: | 1 |
| 6 | Infection by Borrelia burgdorferi and cutaneous B-cell lymphoma显示文摘 | CERRONI L ZOCHING N PUTZ B | 1997 | J Cutan Pathol1997,24,: | 1 |
| 7 | Thermoregulation and rheological properties of blood in primary Raynaud' s phenomenonand the vibration-induced white-finger syndrome显示文摘 | Ziegler S Zoch C Gschwandtner M | 2005 | Int Arch Occup Envion Heaith2005,78,3: | 1 |
| 8 | Predisposing factors and clinical features of eczema herpeticum:a retrospective analysis of 100 cases显示文摘 | Wollenberg A Zoch C Wetzel S | 2003 | J Am Acad Dermatol2003,49,2: | 1 |
| 9 | Expression of glucocorticoid receptors in nephrotic children depending on total prednisone dose 显示文摘 | Wasilewska A Zoch - Zwierz W | 2005 | J Pediatr Endocrinol Metab2005,18,8: | 1 |
| 10 | Response to prednisone in relation to NR3C1 intron B polymorphisms in childhood nephrotic syndrome显示文摘 | ZALEWSKI G WASILEWSKA A ZOCH ZWIERZ W | 2008 | Pediatr Nephrol2008,23,7: | 1 |
| 11 | Lymphocyte subpopulations of peripheral blood in children with Schonlein - Henoeh purpura and lgA nephropathy 显示文摘 | Wiereinski R Zoch - Zwierz W Wasilewska A | 2001 | Pol Merkuriusz Lek2001,10,58: | 1 |
| 12 | Phase diagram of degenerate exciton systems显示文摘 | LAI C W ZOCH J GOSSARD A C | 2004 | Science2004,303,5657: | 1 |
| 13 | Serum and urine leptin concentration in children with nephrotic syndrome 显示文摘 | Wasilewaka A Tomaszewska B Zoch - Zwierz W | 2005 | Pediatr Nephrol2005,20,5: | 1 |
| 14 | Phase diagram of degenerate exciton systems 显示文摘 | Lai C W Zoch J Gossaxd A C | 2004 | Science2004,303,: | 1 |
| 15 | Response to prednisone in relation to NR3C1 intron B polymorphisms in childhood nephrotic syndrome 显示文摘 | ZALEWSKI G WASILEWSKA A ZOCH ZW | 2008 | Pediatr Nephrol2008,23,7: | 1 |
| 16 | Predisposing factors and clinical features of eczema herpeticum: a retrospective analysis of 100 cases显示文摘 | Wollenberg A Zoch C Wetzel S | 2003 | J Am Acad Dermatol2003,49,2: | 1 |
| 17 | Lymphocyte subpopulations of peripheral blood in children with Henoch - Schonlein purpura and IgA nephropathy 显示文摘 | Wiercinski R Zoch -Zwierz W Wasilewska A | 2001 | Pol Merkuriusz Lek2001,10,58: | 1 |
| 18 | Lymphocyte Subpopulations of peipher',~ blood in children with Schonleln - Henoch Purpura and IgA nephropathy 显示文摘 | Wiercinski R Zoch - Zwierz W Wasile Nska A | 2001 | Pol Merkuriusz Lek2001,10,58: | 1 |
| 19 | Long-term results of rtoeopic value open colorectal resections for cancerin235 patient with aminimum follow-up of 5 years显示文摘 | Zoche E Gucrrieri M De Sanctis A | 2006 | Surg Endosc2006,20,4: | 1 |
| 20 | Evaluation of S-N curves with more than one failure mode 显示文摘 | Bomas H Burkart K Zoch H W | 2011 | International Journal of Fatigue2011,33,3: | 1 |