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| 1 | Assessment of the current intensity for preventing ice accretion on overhead conductors显示文摘 | Zsolt P Farzaneh Masoud Kiss Laszlo I | 2007 | IEEE Trans on Power Delivery2007，22，1： | 1 |
| 2 | Laser processing for microelectronics packaging applications显示文摘 | Zsolt I V | 2001 | Microeletronics Reliability2001，41，4： | 1 |
| 3 | Assessment of the current intensity for preventing ice accretion on overhead conductors显示文摘 | Zsolt P Masoud F Laszlo I K | 2007 | IEEE Trans on Power Delivery2007，22，1： | 1 |
| 4 | Assessment of the current intensity for preventing ice accretion on overhead conductors显示文摘 | Zsolt Peter Masoud Farzaneh Laszlo I Kiss | 2007 | IEEETransonPowerDel2007，22，1： | 1 |
| 5 | Comparison of propofol and etomidate regarding impact on seizure threshold during electroconvulsive ther- apy in patients with schizophrenia 显示文摘 | Gabor G Judit T Zsolt I | 2007 | Neuropsychopharrnacol Hung2007，9，3： | 1 |
| 6 | Gene Network Polymorphism Is the Raw Material of Natural Selection: The Selfish Gene Network Hypothesis显示文摘 | Zsolt Boldogk?i | 2004 | Journal of Molecular Evolution2004，，3： | 1 |
| 7 | Laser processing for microelectronics packaging applications显示文摘 | Zsolt I V | 2001 | Microeletronics Reliability2001，41，4： | 1 |
| 8 | Analysis of paraoxonase activity and lipid profile in lupus patients 显示文摘 | Kiss E Seres I Zsolt K | 2005 | Orv HetiL2005，146，47： | 1 |
| 9 | Genetic background of phenotypic variation显示文摘A noteworthy feature of the living world is its bewildering variability. A key issue in several biological disciplines is the achievement of an understanding of the hereditary basis of this variability. Two opposing, but not necessarily irreconcilable conceptions attempt to explain the underlying mechanism. The gene function paradigm postulates that phenotypic variance is generated by the polymorphism in the coding sequences of genes. However, comparisons of a great number of homologous gene and protein sequences have revealed that they predominantly remained functionally conserved even across distantly related phylogenic taxa. Alternatively, the gene regulation paradigm assumes that differences in the cis-regulatory region of genes do account for phenotype variation within species. An extension of this latter concept is that phenotypic variability is generated by the polymorphism in the overall gene expression profiles of gene networks. In other words, the activity of a particular gene is a system property determined both by the cis-regulatory sequences of the given genes and by the other genes of a gene network, whose expressions vary among individuals, too. Novel proponents of gene function paradigm claim that functional genetic variance within the coding sequences of regulatory genes is critical for the generation of morphological polymorphism. Note, however, that these developmental genes play direct regulatory roles in the control of gene expression. | Zsolt Boldogki | 2007 | Progress in Natural Science:Materials International2007，17，10： | 0 |
| 10 | Effect of herpesvirus infection on pancreatic duct cell secretion显示文摘AIM: To examine the effect of acute infection caused by herpesvirus (pseudorabies virus, PRV) on pancreatic ductal secretion.METHODS: The virulent Ba-DupGreen (BDG) and nonvirulent Ka-RREpOlacgfp (KEG) genetically modified strains of PRV were used in this study and both of them contain the gene for green fluorescent protein (GFP). Small intra/interlobular ducts were infected with BDG virus (107 PFU/mL for 6 h) or with KEG virus (1010 PFU/mL for 6 h), while non-infected ducts were incubated only with the culture media. The ducts were then cultured for a further 18 h.The rate of HCO3- secretion [base efflux -J(B-)] was determined from the buffering capacity of the cells and the initial rate of intracellular acidification (1) after sudden blockage of basolateral base loaders with dihydro-4,4,-diisothiocyanatostilbene-2,2,-disulfonic acid (500 μmol/L)and amiloride (200 μmol/L), and (2) after alkali loading the ducts by exposure to NH4Cl. All the experiments were performed in HCO3--buffered Ringer solution at 37 ℃ (n = 5ducts for each experimental condition). Viral structural proteins were visualized by immunohistochemistry. Virallyencoded GFP and immunofluorescence signals were recorded by a confocal laser scanning microscope.RESULTS: The BDG virus infected the majority of accessible cells of the duct as judged by the appearance of GFP and viral antigens in the ductal cells. KEG virus caused a similarly high efficiency of infection. After blockage of basolateral base loaders, BDG infection significantly elevated -J(B-) 24 h after the infection, compared to the non-infected group. However, KEG infection did not modify -J(B-). After alkali loading the ducts, -J(B-) was significantly elevated in the BDG group compared to the control group 24 h after the infection. As we found with the inhibitor stop method, no change was observed in the group KEG compared to the non-infected group.CONCLUSION: Incubation with the BDG or KEG strains of PRV results in an effective infection of ductal epithelial cells. The BDG strain of PRV, which is able to initiate a lytic viral cycle, stimulates HcO3- secretion in guinea pig pancreatic duct by about four- to fivefold, 24 h after the infection. However, the KEG strain of PRV, which can infect,but fails to replicate, has no effect on HCO3- secretion.We suggest that this response of pancreatic ducts to virulent PRV infection may represent a defense mechanism against invasive pathogens to avoid pancreatic injury. | Péter Hegyi Balázs rdg Zoltán Rakonczai Jr Tamás Takács János Lonovics Annamária Szabolcs Réka Sári András Tóth Julius G Papp András Varró Mária K Kovács Mike A Gray Barry E Argent Zsolt Boldogki | 2005 | World Journal of Gastroenterology2005，11，38： | 0 |
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