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| 1 | On modeling with multiplicative differential equations显示文摘This work is aimed to show that various problems from different fields can be modeled more effciently using multiplicative calculus,in place of Newtonian calculus.Since multiplicative calculus is still in its infancy,some effort is put to explain its basic principles such as exponential arithmetic,multiplicative calculus,and multiplicative differential equations.Examples from finance,actuarial science,economics,and social sciences are presented with solutions using multiplicative calculus concepts.Based on the encouraging results obtained it is recommended that further research into this field be vested to exploit the applicability of multiplicative calculus in different fields as well as the development of multiplicative calculus concepts. | Agamirza E.Bashirov Emine Misirli Ycel Tandogdu Ali zyapici | 2011 | Applied Mathematics(A Journal of Chinese Universities)2011，26，4： | 9 |
| 2 | Inhibitory effects of regorafenib, a multiple tyrosine kinase inhibitor, on corneal neovascularization显示文摘AIM:To evaluate the inhibitory effects of regorafenib(BAY 73-4506),a multikinase inhibitor,on corneal neovascularization(NV).METHODS:Thirty adult male Sprague-Dawley rats weighing 250-300 g,were used.Corneal NV was induced by NaOH in the left eyes of each rat.Following the establishment of alkali burn,the animals were randomized into five groups according to topical treatment.Group 1(n=6)received 0.9%NaCl,Group 2(n=6)received dimethyl sulfoxide,Group 3(n=6)received regorafenib 1 mg/mL,Group 4(n=6)received bevacizumab 5 mg/mL and Group 5(n=6)received 0.1%dexamethasone phosphate.On the 7d,the corneal surface covered with neovascular vessels was measured on photographs as the percentage of the cornea's total area using computer-imaging analysis.The corneas obtained from rats were semiquantitatively evaluated for caspase-3 and vascular endothelial growth factor by immunostaining.RESULTS:A statistically significant difference in the percent area of corneal NV was found among the groups(P<0.001).Although the Group 5 had the smallest percent area of corneal NV,there was no difference among Groups 3,4 and 5(P>0.005).There was a statistically significant difference among the groups in apoptotic cell density(P=0.002).The staining intensity of vascular endothelial growth factor in the epithelial and endothelial layers of cornea was significantly different among the groups(P<0.05).The staining intensity of epithelial and endothelial vascular endothelial growth factor was significantly weaker in Groups 3,4 and 5 thanin Groups 1 and 2.CONCLUSION:Topical administration of regorafenib 1mg/mL is partly effective for preventing alkali-induced corneal NV in rats. | Halil Ibrahim Onder Mesut Erdurmus Yasin Yücel Bucak Hüseyin Simavli Murat Oktay Ahmet Sahap Kukner | 2014 | International Journal of Ophthalmology(English edition)2014，7，2： | 4 |
| 3 | Factors Associated With Response to Therapy and Outcome of Patients With Primary Biliary Cirrhosis With Features of Autoimmune Hepatitis显示文摘 | Ersan Ozaslan Cumali Efe Alexandra Heurgué–Berlot Taylan Kav Chiara Masi Tugrul Purnak Luigi Muratori Yücel Ustündag Solange Bresson–Hadni Gérard Thiéfin Thomas D. Schiano Staffan Wahlin Paolo Muratori | 2014 | Clinical Gastroenterology and Hepatology2014，，： | 3 |
| 4 | Protective effects of Rutin against methanol induced acute toxic optic neuropathy:an experimental study显示文摘AIM:To determine the effects of Rutin on methanol induced optic neuropathy and compare the results with the effects of ethanol.METHODS:Totally 30 rats were divided into 5 groups,with 6 rats in each group as follows:healthy controls(C),methotrexate(MTX),methotrexate+methanol(MTM),methotrexate+methanol+ethanol(MTME) and methotrexate+ methanol+Rutin(MTMR).In all rabbits except those of the control group,MTX,diluted in sterile serum physiologic,0.3 mg/kg per oral was applied for 7 d by the aid of a tube.After this procedure to the rats of MTM,MTME and MTMR groups,20% methanol with a dose of 3 g/kg per oral was given by the aid of a tube.In MTME group,4 h after the application of methanol,20% ethanol was applied by the same way with a dose of 0.5 g/kg.On the other hand,in MTMR group 4 h after the application of methanol,Rutin,which was dissolved in distilled water,was applied by the same way with a dose of 50 mg/kg.RESULTS:There were statistically significant differences in tissue 8-hydroxy-2 deoxyguanine(8-OHdG),interleukin-1β(IL-1β),tumor necrosis factor-alpha(TNF-α),malondialdehyde(MDA),myeloperoxidase(MPO).glutathione peroxidase(t GSH) and superoxide dismutase(SOD) levels between groups(P<0.001).In MTMR group tissue 8-OHdG,IL-1β,MDA,and MPO levels were similar with the healthy controls but significantly different than the other groups.In histopathological evaluations,in MTX group there was moderate focal destruction,hemorrhage and decrease innumber of astrocytes and oligodendrocytes;in MTM group there was severe destruction and edema with decrease in number of astrocytes and oligodendrocytes;in MTME group there was mild hemorrhage,mild edema,mildly dilated blood vessels with congestion while in MTMR group,optic nerve tissue was resembling the healthy controls.CONCLUSION:Rutin may prevent methanol-induced optic neuropathy via anti-inflammatory effects and decreasing the oxidative stress.New treatment options are warranted in this disease to avoid loss of vision in patients. | Nurdan Gamze Tasli Ferda Keskin Cimen Yücel Karakurt Turgay Ucak Renad Mammadov Bahadir Suleyman Nezahat Kurt Halis Suleyman | 2018 | International Journal of Ophthalmology(English edition)2018，11，5： | 2 |
| 5 | Prevalence of large cavum septi pellucidi in ultra high-risk individuals and patients with psychotic disorders显示文摘 | Takahashi T Yung AR Yücel M | 2008 | Schizophr Res2008，105，13： | 1 |
| 6 | Simvastatin preserves myocardial perfusion and coronary microvascular permeability in experimental hypercholesterolemia independent of lipid lowering显示文摘 | BONETTI P O WILSON S H RODRIGUEZ-POR- CEL M | 2002 | J Am Coll Cardiol2002，40，： | 1 |
| 7 | Nonoperative manage-ment of post-traumatic pulmonary pseudocyst after severe thoracictrauma and hemorrhage by coagulation management,kinetic thera-py,and control of secondary infection:a case report显示文摘 | Steinhausen E Bouillon B Yücel N | 2007 | J Trauma2007，63，6： | 1 |
| 8 | Effect of fly ash and PVA fiber on microstructural damage and residual properties of engineered cementitious composites exposed to high temperatures 显示文摘 | YAHMARAN M ?ZBAY E YüCEL H | 2011 | J Mater Civ Eng2011，23，17： | 1 |
| 9 | Complications of endoscopic surgery of the pituitary adenomas:analysis of 570patients and review of the literature显示文摘 | BERKER M HAZER D B YCEL T | 2012 | Pituitary2012，15，： | 1 |
| 10 | A 4-year trial of tiotropium in chron-ic obstructive pulmonary disease显示文摘 | Tashkin D Cel i B Senn S | | 0，，15： | 1 |
| 11 | Environmental strategies and organizational competitiveness in the hotel industry: The role of learning and innovation as determinants of environmental success显示文摘 | Elena Fraj Jorge Matute Iguácel Melero | 2015 | Tourism Management2015，，： | 1 |
| 12 | Interpretation of genotype x environment interactions for early maize hybrids over 12 years 显示文摘 | Signor CEL Dousse S Lorgeon J | 2001 | Crop Sci2001，41，： | 1 |
| 13 | Histological evaluation of changes in the temporomandibular joint after direct and indirect trauma:an experimental study显示文摘 | Yücel E B(o)rkan U Mollaoglu N | | 0，，4： | 1 |
| 14 | Juvenile nasopharyngeal angiofibroma:a revised staging system显示文摘 | NERCI M OGRETMENOGLU O YCEL T | 2006 | Rhinology2006，44，： | 1 |
| 15 | Identification of lymphatics in the ciliary body of the human eye:A novel uveolymphatic outflow pathway显示文摘 | Y(U)Cel YH JOHNSTON MG LY T | 2009 | Exp Eye Res2009，89，5： | 1 |
| 16 | Usefulness of Somatosensory and Motor Evoked Potentials for Lesion Localization显示文摘 | Hakan Akgün Mehmet Yücel O?uzhan ?z ?eref Demirkaya | 2013 | Clinical Neurology and Neurosurgery2013，，： | 1 |
| 17 | Stress intensity factor equa-tions for mixed-mode surface and corner cracks in fi-nite-thickness plates subjected to tension loads显示文摘 | AYHAN A O YüCEL U | 2011 | In-ternational Journal of Pressure Vessels and Piping2011，88，5： | 1 |
| 18 | The effect of laparoscopic cho- lecystectomy on the development of alkaline reflux gastritis and intestinal metaplasia显示文摘 | A tak I Ozdil K Y cel M | 2012 | Hepatogastroenterology2012，113，59： | 1 |
| 19 | Degradation ofpicloram by the electro-Fenton process显示文摘 | Aliozcan Yu cel Sahin | 2007 | Journal of Hazardous Materials2007，，： | 1 |
| 20 | Glenohumeral joint subluxation and reflex sympathetic dystrophy in hemiplegia patients显示文摘 | Dursun E Dursun N Ura CEL | 1999 | Arch Phys Med Rehabil1999，81，7： | 1 |
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