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| 1 | Single-center study comparing computed tomography colonography with conventional colonoscopy显示文摘AIM:To compare the results from computed tomography (CT) colonography with conventional colonoscopy in symptomatic patients referred for colonoscopy. METHODS: The study included 227 adult outpatients, mean age 60 years, with appropriate indications for colonoscopy. CT colonography and colonoscopy were performed on the same day in a metropolitan teaching hospital. Colonoscopists were initially blinded to the results of CT colonography but there was segmental unblinding during the procedure. The primary outcome measures were the sensitivity and specificity of CT colonography for the identification of polyps seen at colonoscopy (i.e. analysis by polyp). Secondary outcome measures included an analysis by patient, extracolonic findings at CT colonography, adverse events with both procedures and patient acceptance and preference. RESULTS: Twenty-five patients (11%) were excluded from the analysis because of incomplete colonoscopy or poor bowel preparation that affected either CT colonography, colonoscopy or both procedures. Polyps and masses (usually cancers) were detected at colonoscopy and CT colonography in 35% and 42% of patients, respectively. Of nine patients with a finaldiagnosis of cancer, eight (89%) were identified by CT colonography as masses (5) or polyps (3). For polyps analyzed according to polyp, the overall sensitivity of CT colonography was 50% (95% CI, 39%-61%) but this increased to 71% (95% CI, 52%-85%) for polyps ≥ 6 mm in size. Similarly, specificity for all polyps was 48% (95% CI, 39%-58%) increasing to 67% (95% CI, 56%-76%) for polyps ≥ 6 mm. Adverse events were uncommon but included one colonic perforation at colonoscopy. Patient acceptance was high for both procedures but preference favoured CT colonography. CONCLUSION: Although CT colonography was more sensitive in this study than in some previous studies, the procedure is not yet sensitive enough for widespread application in symptomatic patients. | Ian C Roberts-Thomson Graeme R Tucker Peter J Hewett Peter Cheung Ruben A Sebben EE Win Khoo Julie D Marker Wayne K Clapton | 2008 | World Journal of Gastroenterology2008，14，3： | 4 |
| 2 | Functions encoded by pyrrolnitrin biosynthetic genes from Pseudomonas fluorescens显示文摘 | Kirner S Hammer P E Hill D S Altmann A Fischer I Weislo L J Lanahan M van P_e ee K-H Ligon J M | 1998 | J Bacteriol1998，180，： | 1 |
| 3 | Morphologic cytogenetic and enzymatic variations in Saccharum species hybrid clones drived from callus culture显示文摘 | Heinz D J M ee G W G | 1971 | Amer J Bet1971，，58： | 1 |
| 4 | Needle puncture injury causes acute and long-term mechanical deficiency in a mouse model of inter- vertebral discdegeneration显示文摘 | Martin JT Gorth D J Beattie EE | 2013 | J Orthop Res2013，4，1： | 1 |
| 5 | Four genes from Pseudomonas fluorescens that encode the biosynthesis of pyrrolnitrin显示文摘 | Hammer P E Hill D S Lam S T van P_e ee K-H Ligon M J | 1997 | Appl Environ Microbiol1997，63，： | 1 |
| 6 | Design and manufacture of a carbon fiber epoxy rotating boring bar 显示文摘 | I EE D G YUN HWANG H KOOK KIM J | 2003 | Composite Structures2003，60，1： | 1 |
| 7 | Recombinant CYtA*17 is detective in metabolizing the hypertensive drug nifedipine,and the CYP3A4 * 17 allele may occur on the same chromosome as CY P3 A5 * 3, representing a new putative detective C YIr3 A haplo- type显示文摘 | l ee S J Bell D A Couher S J | 2005 | J Pharmacol Exp Ther2005，313，1： | 1 |
| 8 | Primary hypothy- roidism mimickhn4g a pituitary macroadenoma: regression after thy- roid hormone replacement therapy显示文摘 | Eom K S S ee - Sung C Kim J D | 2009 | Pediatr Radiol2009，39，2： | 1 |
| 9 | Management of renal tumors by image-guided radiofrequency ablation : Experience in105 tumors 显示文摘 | Breen D J Rutherford EE StedmanB | 2007 | Cardiovase Intervent Radio12007，30，5： | 1 |
| 10 | The role of the lung in postinjury multiple organ failure显示文摘 | Ciesla D J Moore EE Johnson JL | 2005 | Surgery2005，138，4： | 1 |
| 11 | Effect of particle size on the room temperature crystal structure of barium titanate显示文摘 | BEGG B D VANCE Ee R NOWOTNY J | 1994 | J Am Ceram Soc1994，77，12： | 1 |
| 12 | Development of ZigBee-based street light control system 显示文摘 | l ee J D | 2006 | Power Systems Conference and Exposition2006，，： | 1 |
| 13 | Third attempt to place implants in sites where previous surgeries have failed 显示文摘 | Maehtei EE Horwitz J Mahler D | 2011 | J Clin Periodontol2011，38，2： | 1 |
| 14 | Outcomes of patients with transient ischemic attack after hospital admission or discharge from the emergency department 显示文摘 | Kehdi EE Cordato D J nonuts PR | 2008 | MedJAust2008，189，1： | 1 |
| 15 | Phase I study of bevacizumab added to fluorouracil-and hydroxyurea-based concomitant chemoradiotherapy for poor-prognosis head and neck cancer显示文摘 | Seiwert TY Haraf D J Cohen EE | 2008 | J Clin Oncol2008，26，10： | 1 |
| 16 | Energy, water, and broad-scale geographic patterns of species richness显示文摘 | Hawkins BA Field R Comell HV Currie D J Guegan JF Kaufman DM Kerr JT Mittelbach GG Oberdorff T O'Brien EM Porter EE Turner JRG 2003a | 2003 | Ecology2003，84，12： | 1 |
| 17 | A systematic approachto the large scale production of protein crystals显示文摘 | EE T S VAGHJIANI J D LYE G J | 2000 | EnzymeMicrob Technol2000，26，： | 1 |
| 18 | Early treatment of congenital unilateral cataract minimizes unequal competition显示文摘 | Birch EE Stager D Leffler J Weakley D | 1998 | Invest Ophthalmol Vis Sci1998，39，： | 1 |
| 19 | The Effectiveness of Early Head Start for 3-Year-old Children and Their Families : Lessons for Policy and Programs显示文摘 | Love JM Kisker EE Ross C Raikes H Constantine J Boiler K Brooks-Gunn J Chazan-Cohen R Tarullo LB Brady-Smith C Fuligni AS Schochet PZ Paulsell D Vogel C | 2005 | Developmental Psychology2005，41，6： | 1 |
| 20 | An- ficorrosive behavior of hydroxyapatite as all environ- mentally friendly pigment 显示文摘 | PARK J H I EE G D NISHIKATA A el al | 2002 | Corrosion Science2002，44，： | 1 |
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