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| 1 | 旅游目的地体验价值:维度辨识、量表开发与验证显示文摘旅游目的地并未须同时具备观赏价值、科学考察价值、历史文化价值等,对于旅游者来说,只要有一种价值非常突出,就足以吸引他们前来旅游。目前,虽然众多学者纷纷赞同体验价值的重要性,但研究成果多关注于'态度-行为'的必然联系,片面地聚焦于体验价值对旅游者行为,特别是游后行为产生的影响,由此对旅游者满意度和忠诚度进行判断,这些研究忽略了目的地体验价值本身所富含的时间规律、空间尺度及体验主体的实践性表达。文章采用质性研究与定量研究相结合的方法,探析旅游目的地体验价值的结构与内涵。研究结果表明,旅游目的地体验价值是以功能价值、享乐价值与符号价值为核心,包含放松、复愈、交流、社会声望等8个子范畴,该量表具有良好的信度与效度。该研究有利于目的地管理者更全面、深刻地理解体验价值的内涵,并为构建基于体验价值的目的地深度旅游体验提供必要的理论基础和技术支持。 | 那梦帆 谢彦君 Dogan Gursoy | 2019 | 旅游学刊2019，34，12： | 36 |
| 2 | 景区规范类标识牌劝说效果研究——基于语言风格与颜色效价的匹配影响显示文摘文章基于情绪启动效应和规范焦点理论,研究了景区规范类标识牌语言风格对旅游者不文明行为的劝说效果,探索标识牌颜色效价与语言风格匹配方式对旅游者行为意愿的影响。研究结果表明:(1)景区标识牌语言风格(理性诉求vs.感性诉求)对旅游者劝说效果影响显著。(2)颜色在中国游客的认知经验中具有积极和消极的心理效价,当标识牌语言风格与标识牌颜色效价(积极vs.消极)达成匹配时,劝说效果更好。(3)概念流畅性是语言风格与颜色效价匹配影响劝说效果的中介变量。文章为提高旅游景区标识牌对旅游不文明行为的道德教育和干预效果提供了理论和方法指导。 | 张梦 潘莉 Dogan GURSOY | 2016 | 旅游学刊2016，31，3： | 15 |
| 3 | Circulating microRNAs in patients with non-alcoholic fatty liver disease显示文摘AIM: To identify novel non-invasive biomarkers for non-alcoholic fatty liver disease(NAFLD). METHODS: Twenty patients with histologically proven NAFLD and 20 controls were included. All NAFLD cases were scored using the NAFLD activity score. The rela-tive expressions of miR-197, miR-146 b, miR-10 b, miR-181d, miR-34 a, miR-122, miR-99 a and miR-29 a were analyzed using real-time polymerase chain reaction. RESULTS: Serum levels of miR-181 d, miR-99 a, miR-197 and miR-146 b were significantly lower in biopsy-proven NAFLD patients than in the healthy controls. Serum lev-els of miR-197 and miR-10 b were inversely correlated with degree of inflammation and miR-181 d and miR-99 a were inversely correlated with serum gamma glu-tamyl transferase levels in non-alcoholic steatohepatitis patients. CONCLUSION: NAFLD is associated with altered se-rum miRNA expression pattern. This study provides clues for defining the non-invasive diagnosis of NAFLD. | Serkan Dogan Gokmen Zararsiz Sebnem Gursoy Kadri Guven Omer Ozbakir Munis Dundar Mehmet Yucesoy | 2014 | World Journal of Hepatology2014，6，8： | 13 |
| 4 | Altered spontaneous contractions of the ileum by anesthetic agents in rats exposed to peritonitis显示文摘AIM:To investigate in vitro effects of propofol,midazolam and dexmedetomidine,which are commonly used anaesthesic or sedatives,on spontaneous contractions of the ileum both in normal rats and those exposed to hyperdynamic peritonitis.METHODS:Spontaneous contractions of isolated ileum muscle segments from sham operated rats and those exposed to peritonitis,were studied in vitro.The amplitude and the frequency of spontaneous contractions of ileum muscle segments were studied after adding dexmetetomidine,propofol,and midazolam to the organ bath in a cumulative manner.RESULTS:Both amplitude(85.2±6.6 vs 47.4±7.1)and frequency(32.8±4.6 vs 20.2±3.9)of spontaneous contractions in ileum smooth muscle segments were decreased significantly in the peritonitis group compared to the control group(P<0.05).Dexmedetomidine significantly increased the amplitude of spontaneous contractions(85.2±6.6 vs 152.0±5.4,P<0.05)whereas,propofol(85.2±6.6 vs 49.6±4.8,P<0.05)and midazolam(85.2±6.6 vs 39.2±4.5,P<0.05)decreased it in both control and peritonitis groups.The frequency of spontaneous contractions were significantly decreased by propofol in both control(32.8±4.6 vs 18.2±3.4,P<0.05)and peritonitis groups 20.2±3.9 vs 11.6±3.2,P<0.05).Dexmedetomidine and midazolam did not cause significant changes in the number of spontaneous contractions in both control and the peritonitis groups(P>0.05).CONCLUSION:Propofol,midazolam and dexmedetomidine have various in vitro effects on spontaneous contractions of the rat ileum.While dexmedetomidine augments the spontaneous contraction of the rat ileum,propofol attenuates it.However,the effects of these compounds were parallel in both control and peritonitis groups. | Cengiz Aydin Ihsan Bagcivan Sinan Gursoy Ahmet Altun Omer Topcu Ayhan Koyuncu | 2009 | World Journal of Gastroenterology2009，15，13： | 6 |
| 5 | Noninvasive assessment of liver damage in chronic hepatitis B显示文摘AIM:To evaluate the efficacy of the aspartate aminotransferase/platelet ratio index(APRI)and neutrophillymphocyte(N/L)ratio to predict liver damage in chronic hepatitis B(CHB).METHODS:We analyzed 89 patients diagnosed with CHB by percutaneous liver biopsy and 43 healthy subjects.Liver biopsy materials were stained with hematoxylin-eosin and Masson’s trichrome.Patients’fibrosis scores and histological activity index(HAI)were calculated according to the Ishak scoring system.Fibrosis score was recognized as follows:F0-1 No/early-stage fibrosis,F2-6 significant fibrosis,F0-4 non-cirrhotic and F5-6 cirrhotic.Significant liver fibrosis was defined as an Ishak score of≥2.APRI and N/L ratio calculation was made by blood test results.RESULTS:The hepatitis B and control group showed no difference in N/L ratios while there was a significant difference in terms of APRI scores(P<0.001).Multiple logistic regression analysis revealed that the only independent predictive factor for liver fibrosis in CHB was platelet count.APRI score was significantly higher in cirrhotic patients than in non-cirrhotic patients.However,this significance was not confirmed by multiple logistic regression analysis.The optimum APRI score cut-off point to identify patients with cirrhosis was 1.01with sensitivity,specificity,positive predictive value and negative predictive value of 62%(36%-86%),74%(62%-83%),29%(13%-49%)and 92%(82%-97%),respectively.In addition,correlation analyses revealed that N/L ratio has a negative and significant relationship with HAI(r=-0.218,P=0.041).CONCLUSION:N/L ratio was negatively correlated with HAI.APRI score may be useful to exclude cirrhosis in CHB patients. | Mehmet Celikbilek Serkan Dogan Sebnem Gursoy Gokmen Zararsιz Alper Yurci Omer Ozbakιr Kadri Guven Mehmet Yucesoy | 2013 | World Journal of Hepatology2013，5，8： | 5 |
| 6 | Epinephrine plus argon plasma or heater probe coagulation in ulcer bleeding显示文摘AIM:To compare the effectiveness of argon plasma coagulation (APC) and heater probe coagulation (HPC) in non-variceal upper gastrointestinal bleeding.METHODS:Eighty-five (18 female,67 male) patients admitted for acute gastrointestinal bleeding due to gastric or duodenal ulcer were included in the study.Upper endoscopy was performed and HPC or APC were chosen randomly to stop the bleeding.Initial hemostasis and rebleeding rates were primary and secondary end-points of the study.RESULTS:Initial hemostasis was achieved in 97.7% (42/43) and 81% (36/42) of the APC and HPC groups,respectively (P < 0.05).Rebleeding rates were 2.4% (1/42) and 8.3% (3/36) in the APC and HPC groups,respectively,at 4 wk (P > 0.05).CONCLUSION:APC is an effective hemostatic method in bleeding peptic ulcers.Larger multicenter trials are necessary to confirm these results. | Ahmet Karaman Mevlut Baskol Sebnem Gursoy Edip Torun Alper Yurci Banu Demet Ozel Kadri Guven Omer Ozbakir Mehmet Yucesoy | 2011 | World Journal of Gastroenterology2011，17，36： | 4 |
| 7 | Low eradication rate of Helicobacterpyloriwith triple 7-14 days and quadriple therapy in Turkey显示文摘AIM:The eradication rate of Helicobacter pylori (H pylon) shows variation among countries and regimens of treatment.We aimed to study the eradication rates of different regimens in our region and some factors affecting the rate of eradication.METHODS:One hundred and sixty-four Hpylori positivepatients (68 males, 96 females; mean age:48±12 years)with duodenal or gastric ulcer without a smoking history were included in the study. The patients were divided into three groups according to the treatment regimens. Omeprazole 20mg, clarithromycin 500mg, amoxicillin 1g were given twice daily for 1 week (Group I) and 2 weeks (Group Ⅱ).Patients in Group Ⅲ received bismuth subsitrate 300mg,tetracyline 500 mg and metronidazole 500mg four times daily in addition to Omeprazole 20mg twice daily.Two biopsies each before and after treatment were obtained from antrum and corpus, and histopathologically evaluated.Eradication was assumed to be successful if no Hpylorus was detected from four biopsy specimens taken after treatment. The effects of factors like age, sex, Hpyloridensity on antrum and corpus before treatment, the total Hpylori density, and the inflammation scores on the rate of Hpylori eradication were evaluated.RESULTS:The overall eradication rate was 42%. The rates in groups Ⅱ and Ⅲ were statistically higher than that in group I (P<0.05). The rates of eradication were 24.5%,40.7% and 61.5% in groups Ⅰ, Ⅱ and Ⅲ, respectively. The eradication rate was negatively related to either corpus Hpylori density or total Hpyloridensity (P<0.05).The median age was older in the group in which the eradication failed in comparison to that with successful eradication (55yr vs 39yr, P<0.001). No correlation between sex and Hpylori eradication was found.CONCLUSION: Our rates of eradication were significantly lower when compared to those reported in literature.We believe that advanced age and high Hpyloridensity are negative predictive factors for the rate of Hpylorieradication. | Yuksel Gumurdulu Ender Serin Birol zer Fazilet Kayaselcuk Kursat Ozsahin Arif Mansur Cosar Murat Gursoy Gurden Gur Ugur Yilmaz Sedat Boyacioglu | 2004 | World Journal of Gastroenterology2004，10，5： | 4 |
| 8 | N M Automated interrogation and adoptive subdivision of shape using medial axis transform显示文摘 | Gursoy H N Patrikalakis | 1991 | Advances in Engineering Software1991，13，56： | 2 |
| 9 | Antioxidant activities, metal contents, total phenolics and flavonoids of seven Morchella species显示文摘 | Nevcihan Gursoy Cengiz Sarikurkcu Mustafa Cengiz M. Halil Solak | 2009 | Food and Chemical Toxicology2009，，9： | 2 |
| 10 | Resident attitudes显示文摘 | Dogan Gursoy Claudia Jurowski Muzaffer Uysal | 2001 | Annals of Tourism Research2001，，1： | 2 |
| 11 | Brucellosis of the spine : evaluation of the clinical, laboratory, and radiological findings of ld patients 显示文摘 | Namiduru M Karaoglan I Gursoy S | 2004 | Rhemnatol Int2004，24，3： | 1 |
| 12 | Comparison of in-sulin monotherapy and combination therapy with insulinand metformin or insulin and rosiglitazone or insulin andacarbose in type 2 diabetes显示文摘 | Yilmaz H Gursoy A Sahin M | 2007 | Acta Diabetol2007，44，4： | 1 |
| 13 | An integrative model of tourists' infornation search behavior 显示文摘 | Gursoy D McCleary K W | 2004 | Annals of Tourism Research2004，31，2： | 1 |
| 14 | Brucellosis of the spine:evaluation of the clinical,laboratory,and radiological findings of 14 patients显示文摘 | Namiduru M Karaoglan I Gursoy S | | 0，，3： | 1 |
| 15 | Residents' support for tourism: An identity perspective显示文摘 | Nunkoo R Gursoy D | 2012 | Annals of Tourism Research2012，39，1： | 1 |
| 16 | Photodynamic therapy in dentistry : a literature review 显示文摘 | Gursoy H Ozcakir-Tommk C Tanalp J | 2012 | Clin Oral Invest2012，17，4： | 1 |
| 17 | Self-emulsifying drug delivery systems for improved oral delivery of lipophilic drugs显示文摘 | Gursoy RN Benita S | 2004 | Biomedicine Pharmacotherapy2004，58，： | 1 |
| 18 | Self-emulsifying drug delivery systems(SEDDS)for improved oral delivery of lipophilic drugs显示文摘 | Gursoy R N Benita S | 2004 | Bi-omed Pharmacother2004，58，3： | 1 |
| 19 | An investigation of tourists' destination loyalty and preferences 显示文摘 | CHEN J S GURSOY D | 2001 | International Journal of Con- temporary Hospitality Management2001，13，2： | 1 |
| 20 | A nanomedicine transports a peptide caspase - 3 inhibitor across the blood - brain barrier and provides neuroproteetion 显示文摘 | Karatas H Aktas Y Gursoy - Ozdemir Y | 2009 | J Neurosci2009，29，13： | 1 |
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