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| 1 | High-density circulating fluidized bed gasifier for advanced IGCC/IGFC-Advantages and challenges显示文摘Coal-fired Integrated Gasification Combined Cycle(IGCC)and Integrated coal Gasification Fuel-cell Combined cycle(IGFC)are being developed as high-efficiency electric power generation technology.However,the highest theoretical gross thermal efficiency of the conventional IGCC/IGFC is still below 52%.In order to obtain higher power generation efficiency,an advanced IGCC(A-IGCC)or advanced IGFC(A-IGFC)system making use of the exergy recuperation concept by recycling waste heat from gas turbine or fuel cells for steam gasification of coal and biomass was proposed in our laboratory.Corresponding to this system,a novel high-density triple-bed combined circulating fluidized bed(TBCFB)gasifier,composed of a downer pyrolyzer,a bubbling fluidized bed char gasifier,and a riser combustor,was proposed to replace traditional gasifiers such as the entrained flow bed gasifier.The new system is expected to more effectively utilize the waste heat from gas turbines or fuel cells and the heat produced by the combustion of the unreacted char in the riser combustor for pyrolysis and gasification of coal and biomass.In this short review,the advantages and future challenges in the development of high-density TBCFB gasifier are presented and discussed. | Guoqing Guan Chihiro Fushimi Atsushi Tsutsumi Masanori Ishizuka Satoru Matsuda Hiroyuki Hatano Yoshizo Suzuki | 2010 | Particuology2010，8，6： | 17 |
| 2 | Current status and challenges in sentinel node navigation surgery for early gastric cancer显示文摘As an optimal surgical procedure to accurately evaluate lymph node(LN)metastasis during surgery with minimal surgical resection,we have been developing sentinel node(SN)biopsy for early gastric cancer since the 1990s.Twelve institutions from the Japanese Society of Sentinel Node Navigation Surgery(SNNS),including Keio University Hospital,conducted a multicenter prospective trial to validate the SN concept using the dual-tracer method with blue dye and a radioisotope.According to the results,397 patients were included in the final analysis,and the overall accuracy in detecting LN metastasis using SN biopsy was 99%(383 of 387).Based on the validation study,we are targeting cT1N0 with a primary tumor of≤4 cm in diameter as an indication for SN biopsy for gastric cancer.We are currently running a multicenter nonrandomized phaseⅢtrial to assess the safety and efficacy of SN navigation surgery.The Korean group has reported the result of a multicenter randomized phaseⅢtrial.Since meticulous gastric cancer in the remnant stomach was rescued by subsequent gastrectomy,the disease-specific survival was comparable between the two techniques,implying that SN navigation surgery can be an alternative to standard gastrectomy.With the development of SN biopsy procedure and treatment modalities,the application of SN biopsy will be expanded to achieve an individualized minimally invasive surgery. | Satoru Matsuda Tomoyuki Irino Hirofumi Kawakubo Hiroya Takeuchi Yuko Kitagawa | 2021 | Chinese Journal of Cancer Research2021，33，2： | 3 |
| 3 | CXCL12 secreted from glioma stem cells regulates their proliferation显示文摘 | Youji Uemae Eiichi Ishikawa Satoru Osuka Masahide Matsuda Noriaki Sakamoto Shingo Takano Kei Nakai Tetsuya Yamamoto Akira Matsumura | 2014 | Journal of Neuro-Oncology2014，，1： | 1 |
| 4 | Syntheses and third- order nonli near optical properties of the polydiacetyl enes with sulfur atoms directly bound to the main chain 显示文摘 | Shimada Satoru Matsuda Hiro Masaki Atsushi | 1994 | Molecular Crystals and Liquid Crystals Science and Technology Section B: Nonlinear Optics1994，13，13： | 1 |
| 5 | Impact of endoscopic submucosal dissection knife on risk of perforation with an animal model‐monopolar needle knife and with a bipolar needle knife显示文摘 | Satoru Nonaka Yutaka Saito Shusei Fukunaga Taku Sakamoto Takeshi Nakajima Takahisa Matsuda | 2012 | Digestive Endoscopy2012，，5： | 1 |
| 6 | Association of anastomotic leakage with long-term oncologic outcomes of patients with esophagogastric junction cancer显示文摘BACKGROUND Despite improvements in surgical procedures and peri-operative patients management,the postoperative complications in esophagogastric junction(EGJ)cancer remain high because of technical aspects.Several studies have indicated the negative influence of postoperative infectious complications on long-term survival after gastrointestinal surgery.However,no study has shown the association between postoperative complications and long-term survival of patients with EGJ cancer.AIM To elucidate influence of postoperative complications on the long-term outcomes of patients with EGJ cancer.METHODS A total of 122 patients who underwent surgery for EGJ cancer at the Keio University were included in this study.We examined the association between complications and long-term oncologic outcomes.RESULTS In all patients,the 3-year overall survival(OS)rate was 71.9%,and the recurrencefree survival(RFS)rate was 67.5%.Compared with patients without anastomotic leakage,those with anastomotic leakage had poor median OS(8 mo vs not reached,P=0.028)and median RFS(5 mo vs not reached,P=0.055).Among patients with cervical anastomosis,there were not significant differences between patients with and without anastomotic leakage.However,among patients who underwent intrathoracic anastomosis,patients with anastomotic leakage had significantly worse OS(P=0.002)and RFS(P=0.005).CONCLUSION Anastomotic leakage was significantly associated with long-term oncologic outcomes of patients with EGJ cancer,especially those who underwent intrathoracic anastomosis.Cervical anastomosis with subtotal esophagectomy may be an option for the patients who are at high risk for anastomotic leakage. | Masashi Takeuchi Hirofumi Kawakubo Satoru Matsuda Shuhei Mayanagi Tomoyuki Irino Jun Okui Kazumasa Fukuda Rieko Nakamura Norihito Wada Hiroya Takeuchi Yuko Kitagawa | 2022 | World Journal of Gastrointestinal Surgery2022，14，1： | 1 |
| 7 | Ultrafine particle fluidization and its application to photocatalytc NOx treatment显示文摘 | Hiroyuki Hatano Atsushi Tsutsumi | 2001 | Chemical Engineering Journal2001，82，： | 1 |
| 8 | PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis显示文摘 | Naoko Okumura Hitomi Yoshida Yasuko Kitagishi Mutsumi Murakami Yuri Nishimura Satoru Matsuda Michael L. Grossbard | 2012 | Advances in Hematology2012，，： | 1 |
| 9 | Neuroprotection by dipeptidyl-peptidase-4 inhibitors and glucagonlike peptide-1 analogs via the modulation of AKT-signaling pathway in Alzheimer’s disease显示文摘Alzheimer’s disease(AD)is the most common reason for progressive dementia in the elderly.It has been shown that disorders of the mammalian/mechanistic target of rapamycin(mTOR)signaling pathways are related to the AD.On the other hand,diabetes mellitus(DM)is a risk factor for the cognitive dysfunction.The pathogenesis of the neuronal impairment caused by diabetic hyperglycemia is intricate,which contains neuro-inflammation and/or neurodegeneration and dementia.Glucagon-like peptide-1(GLP1)is interesting as a possible link between metabolism and brain impairment.Modulation of GLP1 activity can influence amyloid-beta peptide aggregation via the phosphoinositide-3 kinase/AKT/mTOR signaling pathway in AD.The GLP1 receptor agonists have been shown to have favorable actions on the brain such as the improvement of neurological deficit.They might also exert a beneficial effect with refining learning and memory on the cognitive impairment induced by diabetes.Recent experimental and clinical evidence indicates that dipeptidyl-peptidase-4(DPP4)inhibitors,being currently used for DM therapy,may also be effective for AD treatment.The DPP-4 inhibitors have demonstrated neuroprotection and cognitive improvements in animal models.Although further studies for mTOR,GLP1,and DPP4 signaling pathways in humans would be intensively required,they seem to be a promising approach for innovative AD-treatments.We would like to review the characteristics of AD pathogenesis,the key roles of mTOR in AD and the preventive and/or therapeutic suggestions of directing the mTOR signaling pathway. | Yuka Ikeda Nozomi Nagase Ai Tsuji Yasuko Kitagishi Satoru Matsuda | 2021 | World Journal of Biological Chemistry2021，12，6： | 1 |
| 10 | Photocatalytic removal of NO x in a circulating fluidized bed system显示文摘 | Satoru Matsuda Hiroyuki Hatano | 2004 | Powder Technology2004，，1： | 1 |
| 11 | Mesoscopic spatial designs of nano-and microfiber meshes for tissue-engineering matrix and scaffold based on newly devised multilayering and mixing electrospinning techniques 显示文摘 | Kidoaki Satoru Kwon Il Kuen Matsuda Takehisa | 2005 | Biomaterials2005，26，： | 1 |
| 12 | Simultaneous determination of six adenyl purines in human plasma by high-performance liquid chromatography with fluorescence derivatization显示文摘 | Masatoki Katayama Yoshifumi Matsuda Ken-ichi Shimokawa Shinzo Tanabe Satoru Kaneko Izumi Hara Hirohisa Sato | 2001 | Journal of Chromatography B: Biomedical Sciences and Applications2001，，1： | 1 |
| 13 | In search of a function for the TIS21/PC3/BTG1/TOB family显示文摘 | Satoru Matsuda Jean-Pierre Rouault Jean-Pierre Magaud Cyril Berthet | 2001 | FEBS Letters2001，，2： | 1 |
| 14 | Ultrafine particle fluidization and its application to photocatalytic NOx treatment显示文摘 | Satoru Matsuda Hiroyuki Hatano Atsushi Tsutsumi | 2001 | Chemical Engineering Journal2001，82，13： | 1 |
| 15 | Ultratine perticle fluldization and its application to photocatalytic NOx treatment显示文摘 | Satoru Matsuda Hiroyuke Hatano Atsushi Tsutsumi | 2001 | Chemical Engineeding Journal2001，82，： | 1 |
| 16 | Mesoscopic spatial designs of nano-and micro, ber meshes for tissue-engineering matrix and scaffold based on newly devised multilayering and mixing electrospinning techniques 显示文摘 | Satoru Kidoaki Il Kuen Kwon Takehisa Matsuda | 2005 | Biomaterials2005，，26： | 1 |
| 17 | Clinical outcome of endoscopic resection for nonampullary duodenal tumors显示文摘 | Satoru Nonaka Ichiro Oda Kazuhiro Tada Genki Mori Yoshinori Sato Seiichiro Abe Haruhisa Suzuki Shigetaka Yoshinaga Takeshi Nakajima Takahisa Matsuda Hirokazu Taniguchi Yutaka Saito Iruru Maetani | 2014 | Endoscopy2014，，： | 1 |
| 18 | By using either endogenous or transplanted stem cells,which could you prefer for neural regeneration?显示文摘Neural regeneration by stem cells transplantation:Tissue regeneration and homeostasis are principally dependent on tissue stem cells which possess abilities of self-renewal and differentiation into multidirectional specialized cell types.In general,stem cells are critical for normal tissue renewal as well as repair after tissue injury.For example,mesenchymal stromal cells and endothelial progenitor cells identified in bone marrow | satoru matsuda yukie nakagawa kumi amano yuka ikeda ai tsuji yasuko kitagishi | 2018 | Neural Regeneration Research2018，13，10： | 1 |
| 19 | Genistein downregulates presenilin 1 and ubiquilin 1 expression显示文摘 | Naoko Okumura Hitomi Yoshida Yuri Nishimura Mutsumi Murakami Yasuko Kitagishi Satoru Matsuda | 2012 | Molecular Medicine Reports2012，，： | 1 |
| 20 | Freehand Sketch System for 3D Geometric Modeling显示文摘 | Koichi Matsuda Satoru Sugishita Zheng Xu | 1997 | IEEE1997，，： | 1 |
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