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| 1 | Sporadic versus hereditary gastrinomas of the duodenum and pancreas: Distinct clinico-pathological and epidemiological features显示文摘Gastrinomas are defined as gastrin secreting tumors that are associated with Zollinger-Ellison syndrome (ZES). ZES is characterized by elevated fasting gastrin serum levels, positive secretin stimulation test and clinical symptoms such as recurrent peptic ulcer disease, gastroesophageal re?ux disease and occasional diarrhea. Genetically, nonhereditary (sporadic) gastrinomas are distinguished from hereditary gastrinomas, which are associated with multiple endocrine neoplasia type 1 (MEN1) syndrome. In general, duodenal gastrinomas are small and solitary if they are sporadic and multiple as well as hereditary. The sporadic gastrinomas occur in the duodenum or in the pancreas while the hereditary gastrinomas almost all occur in the duodenum. Our series of 77 sporadic duodenal neuroendocrine tumors (NETs) includes 18 patients (23.4%) with gastrinomas and ZES. Of 535 sporadic NETs in the pancreas collected from the NET archives of the departments of pathology in Zürich, Switzerland, and Kiel, Germany, 24 patients (4.5%) suffered from sporadic pancreatic gastrinomas and ZES. These NETs have to be distinguished fromtumors with immunohistochemical positivity for gastrin but without evidence of ZES. An additional 19 patients suffered from MEN1 and ZES. These patients showed exclusively duodenal gastrinomas, but not pancreatic gastrinomas. The prognosis of sporadic and MEN1- associated duodenal gastrinomas is better than that of pancreatic gastrinomas, since they progress slowly to liver metastasis. In summary, sporadic and MEN1- associated gastrinomas in the duodenum and pancreas show different clinico-pathological and genetic features. The incidence of sporadic duodenal gastrin-producing tumors is increasing, possibly due to optimized diagnostic procedures. In contrast, pancreatic MEN1- associated gastrinomas seem to be extremely rare. A considerable subset of tumors with immunohistochemical expression of gastrin but without evidence of ZES should be designated as functionally inactive NETs expressing gastrin, but not as gastrinomas. | Martin Anlauf Nele Garbrecht Tobias Henopp Anja Schmitt Regina Schlenger Andreas Raffel Markus Krausch Oliver Gimm Claus F Eisenberger Wolfram T Knoefel Henning Dralle Paul Komminoth Philipp U Heitz Aurel Perren Günter Klppel | 2006 | World Journal of Gastroenterology2006，12，34： | 7 |
| 2 | 健康领域的文化能力显示文摘1背景
尽管人类对其他社会的兴趣纵贯历史的各个阶段,但是检验不同文化概念对人类健康实践的影响从20世纪才开始,当时是伴随着长期的人类学田野调查产生的,这些田野调查揭露了不同文化之间相关卫生实践的多样性、复杂性和连续性。 | Napier A D Ancarno C Butler B Calabrese j Chater A Chatterjee H Guesnet F Home R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams AC Willott C Wilson J Woolf K | 2016 | 中国卫生政策研究2016，9，2： | 5 |
| 3 | 欧洲和中国的心脏与肾脏远程缺血预适应研究:一项随机对照试验显示文摘远程缺血预适应(remote ischemic preconditioning,RIPC)对经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂肾病(contrast-induced nephropathy,CIN)的潜在保护作用尚待确定。该研究为双盲、随机、安慰剂对照的多中心研究,纳入年龄〈85岁,肾清除率为30~60mL/(min·1.73m^2)的有临床适应证的患者,除了直接PCI外均按1∶1给予RIPC或标准治疗。主要终点是CIN的发生率。次要终点是围手术期心肌梗死(peri-procedural myocardial infarction,PMI)的发生率。 | 刘青 叶鹏 Moretti C Cerrato E Cavallero E Lin S Rossi ML Picchi A Sanguineti F Ugo F Palazzuoli A Bertaina M Presbitero P Shao-Liang C Pozzi R Giammaria M Limbruno U Lefèvre T Gasparetto V Garbo R OmedèP Sheiban I Escaned J Biondi-Zoccai G Gaita F Perl L D'Ascenzo F | 2018 | 中华高血压杂志2018，26，4： | 3 |
| 4 | 文化、不平等性与卫生服务提供显示文摘1动态不平等性对基层医疗卫生人力的影响
政治、社会、文化、专业群体皆建立在一致且常规的人类行为之上。当遭受巨大变革和内外压力时,这些群体会变得十分脆弱。尤其在动荡时期,这些群体往往更关注社会和文化的差异性,而非二者的一致性。尽管社会中的个体思维和行为会呈现较大的差异,但对健康的感知具有统一性,并在更广范围人群内尤为突出,这主要归因于文化价值观的作用。广义的文化心态会随着时间和地理位置的不同而不同,就像健康的社会决定因素也会因文化类型的不同而产生差异。 | Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson J Woolf K | 2016 | 中国卫生政策研究2016，9，3： | 2 |
| 5 | Kontrastmittelsonografie bei B-Bild-morphologisch unklaren Leberraumforderungen – Diagnostische Treffsicherheit im klinischen Alltag (DEGUM-Multicenter – Studie)显示文摘 | D Strobel K Seitz W Blank A Schuler C Dietrich A Herbay M Friedrich-Rust G Kunze D Becker U Will W Kratzer F Albert C Pachmann K Dirks H Strunk C Greis T Bernatik | 2008 | Ultraschall in Med2008，，05： | 2 |
| 6 | The effect corrosion defects on the burst pressure of Pipelines显示文摘 | Netto T A Ferraz U S Esterfen S F | 2005 | Journal of Constructional Steel Research2005，，61： | 1 |
| 7 | Reconfiguable manufacturing systems显示文摘 | Koren Y Heisel U Jovane F Mofiwaki T Pritchow G Ulsoy G Van Brussel H | 1999 | Annals of the CIRP1999，48，2： | 1 |
| 8 | Murine Monoclonal Antibodies Directed to the Human Histo-blood Group A Transferase and the Presence Therein of N- Linked Histo-Blood Group A Determinant 显示文摘 | White T Mandel U Orntoft T F | 1990 | Biochemistsy1990，29，11： | 1 |
| 9 | Immunohistological detection of Parvovirus B19 capsid proteins in endomyocardial biopsies from dilated cardiomyopathy patients显示文摘 | Escher F Kuhl U Sabi T | 2008 | Medl Sci Monitor2008，14，6： | 1 |
| 10 | Medical prevention and treatmerit of acute and chronic radiation induced enteritis is there any proven therapy显示文摘 | Zimmerer T Btieker U Wenz F | 2008 | Gastroenteml2008，46，5： | 1 |
| 11 | Arterial stiffness and risk of cor onary heart disease and stroke: the Rotter-dam Study 显示文摘 | MATTACE RASO F U VAN DER CAMMEN T J HOFMAN A | 2006 | Circulation2006，113，： | 1 |
| 12 | Lipid-binding proteins in membrane digestion, antigen presentation, and antimicrobial defense 显示文摘 | KOLTER T WINAU F SCHAIBLE U E | 2005 | J Biol Chem2005，280，41： | 1 |
| 13 | Re-equilibration of zircon in aqueous fluids and melts 显示文摘 | Geisler T Sehaltegger U Tomaschek F | 2007 | Elements2007，3，： | 1 |
| 14 | Symmetrically arranged quartz tuning fork with soft cantilever for intermittent contact mode atomic force microscopy显示文摘 | Akiyama T Staufer U Rooij N F | 2003 | Review of Scientific Instruments2003，74，1： | 1 |
| 15 | Revised recommenda- tions on screening for chloroquine and hydroxychloroquine reti- nopathy显示文摘 | Marmor M F Kenner U Lai T Y | 2011 | Ophthalmology2011，118，2： | 1 |
| 16 | Percutaneous ethanol injection therapy in the treatment ofthyroid and parathyroid diseases显示文摘 | B E N N E D B A E K F N K A R S T R U P S HE G E D U S L | 1997 | Eur J Endocrinol1997，136，3： | 1 |
| 17 | Towards high-capa- city HTS flywheel systems 显示文摘 | WERFEL F N DELOR U F RIEDEL T | 2010 | IEEE Transactions on Applied Superconductivity2010，20，4： | 1 |
| 18 | Vulvovaginal candidiasis:species distribution,fluconazole resistance and drug efflux pump geneoverexpression显示文摘 | Z H A N G J Y L I U J H L I U F D e t a l | 2014 | Mycoses2014，57，10： | 1 |
| 19 | 医疗卫生保健文化的反思及促进健康与文化融合的建议显示文摘1医疗卫生保健文化的反思1.1健康文化与医学知识如果医务人员有充足的时间对患者进行诊断并帮助患者进行社区护理,就可在节省卫生费用的同时改善健康结果。整合型社区护理能缩小不同文化背景和群体健康需求的差异。然而,全球范围内对整合型社区护理的投入较少,原因之一就是20世纪对临床服务的重视弱化了卫生服务提供过程中的同情心理。当然,患者也对医学知识存在显性和隐性的影响(特别是当其因不遵医嘱而受到指责时)。 | Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson JWoolf K | 2016 | 中国卫生政策研究2016，9，4： | 1 |
| 20 | Fluorine-18 fluorodeoxyglucose positron emission tomography in thyroid cancer: results of a multicenter study显示文摘 | Grunwald F Kalicke T Feine U et al | 1999 | Eur J Nucl Med1999，26，： | 1 |
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